Folate and neurotransmitter metabolites

Description / Indication

Neurotransmitter defects, pterin synthesis and regeneration defects, phenylketonuria, cerebral folate deficiency, folate transport defects.

In plasma, only the pterins (total neopterin and total bopterin) are determined.

In CSF, the pterins (total neopterin and total bopterin), phenolic acids (5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol (MHPG), 3-O-Methyldopa (3-OMD ), VLA (vanillactic acid)) and 5-hydroxytryptophan (5-HTP) and 5-methyltetrahydrofolate (5-MTHF) are determined.

Method

LC-MS/MS

TAT

4 weeks

Price

€ 216

Materials:


CSF

Plasma

  • Amount: 500 µl.
  • Conditions: Dry ice.
  • Specifics: EDTA plasma (preferred material), heparin plasma also suitable.