Prof. W.J. Wiersinga MD PhD publications

Publications Prof. MD PhD W.J. Wiersinga

Position

Full Professor

Main activities

Patient care, Research

Specialisation

Internal medicine, infectious diseases

Focus of research

Professor Joost Wiersinga, MD, PhD, Amsterdam, the Netherlands is chair of the Division of Infectious Diseases of the Academic Medical Center, University of Amsterdam. He received his medical training at the University of Amsterdam with additional courses at the Mayo Clinic (Rochester, Minnesota) and the National Institutes of Health (NIH, Bethesda, MD).

He received his PhD thesis entitled “On Toll-like receptors and the innate immune response in melioidosis”, cum laude (Professor Tom van der Poll and professor Sharon Peacock); during this period he worked in Bangkok at the Wellcome Trust Overseas Programme. Previous awards included the O'Callaghan PhD award, the Andreas Bonn medallion, the GSK ICAAC award, the ESCMID Young Investigator Award and the ANZICS Global Rising Star Award 2015.

He divides his time between patient care, teaching and research in the Center for Experimental Molecular Medicine (CEMM) all at the Academic Medical Center, Amsterdam. He investigates innate immune responses in sepsis, caused by Streptoccus pneumonia, Klebsiella pneumonia, Burkholderia pseudomallei and Salmonella typhi. Recent interests include the role of the gut microbiota during severe bacterial infections. His work has been published in among others Nat Rev Microbiol, Gut, JAMA Internal Medicine, PLoS Medicine and N Engl J Med.

Focus of research:

Host-pathogen interactions and innate immune responses in infectious diseases
Special interest in: sepsis, pneumonia, cellulitis, typhoid fever, melioidosis, gut microbiota

Amsterdam UMC Research Institutes

AII - Infectious diseases

AMC departments

All publications

2021

Smit Colette, Boyd Anders, Rijnders Bart J. A., van de Laar Thijs J. W., Leyten Eliane M., Bierman Wouter F., Newsum Astrid M., Schinkel Janke, Prins Maria, van der Valk Marc, Reiss Peter, van der Valk M., Geerlings S. E., Goorhuis A., Hovius J. W., Nellen F. J. B., van der Poll T., Prins J. M., van Vugt M., Wiersinga W. J., Wit F. W. M. N., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Wolthers K. C., Sigaloff K. C. E., Ang C. W., Reuwer A., Nellen J., van Nood E., Renckens R., Kok M., Hoogerwerf J., Richel O., Stelma F. F., Langebeek N., Lauw F. N., van Wijk M., Bakker M., Stienstra Y., Reiss P., Bezemer D. O., van Sighem A. I., Smit C., van de Sande L., Groters M., Schoorl M. HCV micro-elimination in individuals with HIV in the Netherlands 4 years after universal access to direct-acting antivirals: a retrospective cohort study Lancet HIV 2021;8 (2):e96-e105 [PubMed]
Sieswerda Elske, de Boer Mark G. J., Bonten Marc M. J., Boersma Wim G., Jonkers René E., Aleva Roel M., Kullberg Bart-Jan, Schouten Jeroen A., van de Garde Ewoudt M. W., Verheij Theo J., van der Eerden Menno M., Prins Jan M., Wiersinga W. Joost Recommendations for antibacterial therapy in adults with COVID-19 – an evidence based guideline Clinical microbiology and infection 2021;27 (1):61-66 [PubMed]
Joost Wiersinga W., de Bree Godelieve J. Re-infectie met SARS-CoV-2 Nederlands tijdschrift voor geneeskunde 2021;165 (2)
Schinkel Michiel, Virk Harjeet S., Nanayakkara Prabath W.B., Wiersinga W. Joost, van der Poll Tom What Sepsis Researchers Can Learn from COVID-19 American journal of respiratory and critical care medicine 2021;203 (1):125-127 [PubMed]

2020

van Mourik Niels, Geerts Bart F, Binnekade Jan M, Veelo Denise P, Bos Lieuwe D J, Wiersinga W Joost, van der Poll Tom, Cremer Olaf L, Schultz Marcus J, Vlaar Alexander P J A Higher Fluid Balance in the Days After Septic Shock Reversal Is Associated With Increased Mortality: An Observational Cohort Study Critical Care Explorations 2020;2 (10):e0219 [PubMed]
Haak Bastiaan W., de Jong Hanna K., Kostidis Sarantos, Giera Martin, Maude Rapeephan R., Samad Rasheda, Wijedoru Lalith, Ghose Aniruddha, Faiz Mohammed Abul, Parry Christopher M., Wiersinga W. Joost Altered patterns of compositional and functional disruption of the gut microbiota in typhoid fever and nontyphoidal febrile Illness Open forum infectious diseases 2020;7 (7) [PubMed]
Cranendonk D. R., Opmeer B. C., van Agtmael M. A., Branger J., Brinkman K., Hoepelman A. I. M., Lauw F. N., Oosterheert J. J., Pijlman A. H., Sankatsing S. U. C., Soetekouw R., Veenstra J., de Vries P. J., Prins J. M., Wiersinga W. J. Antibiotic treatment for 6 days versus 12 days in patients with severe cellulitis: a multicentre randomized, double-blind, placebo-controlled, non-inferiority trial Clinical microbiology and infection 2020;26 (5):606-612 [PubMed]
Cranendonk D. R., Prins J. M., Wiersinga W. J. 'Antibiotic treatment for 6 days versus 12 days in patients with severe cellulitis' - Author's reply Clinical microbiology and infection 2020;26 (5):656-657 [PubMed]
Vlaar Alexander P. J., de Bruin Sanne, Busch Matthias, Timmermans Sjoerd A. M. E. G., van Zeggeren Ingeborg E., Koning Rutger, ter Horst Liora, Bulle Esther B., van Baarle Frank E. H. P., van de Poll Marcel C. G., Kemper E. Marleen, van der Horst Iwan C. C., Schultz Marcus J., Horn Janneke, Paulus Frederique, Bos Lieuwe D., Wiersinga W. Joost, Witzenrath Martin, Rueckinger Simon, Pilz Korinna, Brouwer Matthijs C., Guo Ren-Feng, Heunks Leo, van Paassen Pieter, Riedemann Niels C., van de Beek Diederik Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial The Lancet Rheumatology 2020;2 (12):e764-e773
Haak Bastiaan W., Wiersinga W. Joost Author Correction: Uncovering hidden antimicrobial resistance patterns within the hospital microbiome (Nature Medicine, (2020), 26, 6, (826-828), 10.1038/s41591-020-0919-z) Nature medicine 2020;26 (12):1950 [PubMed]
Tawfik Dina M., Lankelma Jacqueline M., Vachot Laurence, Cerrato Elisabeth, Pachot Alexandre, Wiersinga W. Joost, Textoris Julien Comparison of host immune responses to LPS in human using an immune profiling panel, in vivo endotoxemia versus ex vivo stimulation Scientific reports 2020;10 (1):9918 [PubMed]
Brands Xanthe, Haak Bastiaan W., Klarenbeek Augustijn M., Otto Natasja A., Faber Daniël R., Lutter René, Scicluna Brendon P., Wiersinga W. Joost, van der Poll Tom Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia Frontiers in immunology 2020;11 [PubMed]
Birnie Emma, Koh Gavin C. K. W., Löwenberg Ester C., Meijers Joost C. M., Maude Rapeephan R., Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga W. Joost Correction: Increased von willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis (PLoS Negl Trop Dis 11(3), e0005468, 10.1371/journal.pntd.0005468 PMID: 28296884) PLoS neglected tropical diseases 2020;14 (9) [PubMed]
Brands Xanthe, Haak Bastiaan W., Klarenbeek Augustijn M., Otto Natasja A., Faber Daniël R., Lutter René, Scicluna Brendon P., Wiersinga W. Joost, van der Poll Tom Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia (Front. Immunol, (2020), 11, (796), 10.3389/fimmu.2020.00796) Frontiers in immunology 2020;11 [PubMed]
Haak Bastiaan W., Westendorp Willeke F., van Engelen Tjitske S. R., Brands Xanthe, Brouwer Matthijs C., Vermeij Jan-Dirk, Hugenholtz Floor, Verhoeven Aswin, Derks Rico J., Giera Martin, Nederkoorn Paul J., de Vos Willem M., van de Beek Diederik, Wiersinga W. Joost Disruptions of Anaerobic Gut Bacteria Are Associated with Stroke and Post-stroke Infection: a Prospective Case–Control Study TRANSLATIONAL STROKE RESEARCH 2020 [PubMed]
Jacobs Max C., Lankelma Jacqueline M., Wolff Nora S., Hugenholtz Floor, de Vos Alex F., van der Poll Tom, Wiersinga W. Joost Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation PLoS ONE 2020;15 (11 November) [PubMed]
Hoornenborg Elske, Coyer Liza, Boyd Anders, Achterbergh Roel Christiaan Alfons, Schim van der Loeff Maarten Franciscus, Bruisten Sylvia, de Vries Henry John Christiaan, Koopsen Jelle, van de Laar Thijs J. W., Prins Maria, van Bergen J. E. A. M., de Bree G. J., Brokx P., Deug F., Heidenrijk M., Prins M., Reiss P., van der Valk M., Davidovich U., Geerlings S. E., Hoornenborg E., Oomen A., Sighem A. van, Zuilhof W., Bruinderink M. L. Groot, Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Bezemer D., van Bijnen A., Dijkstra M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., Hankins C. A., Hogewoning A., Hovius J. W., Kootstra N. A., Lauw F., van der Meer J. T., Mulder B. J., Nellen F. J., van der Poll T., van Rooijen M. S., Sonder G. J., de Vries H. J., Wiersinga W. J., Wit F. W. High incidence of HCV in HIV-negative men who have sex with men using pre-exposure prophylaxis Journal of hepatology 2020;72 (5):855-864 [PubMed]
Alban Andres, Chick Stephen E., Dongelmans Dave A., Vlaar Alexander P. J., Sent Danielle, van der Sluijs Alexander F., Wiersinga W. Joost ICU capacity management during the COVID-19 pandemic using a process simulation Intensive care medicine 2020;46 (8):1624-1626 [PubMed]
Haak Bastiaan W. Intestinal microbiota and host defense in systemic infectious diseases: Translational studies in the healthy and the ill 2020. 373p. ISBN 9789463759045. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga Willem J., Levi Marcel M.; Co-supervisor: van der Poll Tom)
Virk Harjeet Singh, Mukhopadhyay Chiranjay, Wiersinga W. Joost Melioidosis: A Neglected Cause of Community-Acquired Pneumonia Seminars in respiratory and critical care medicine 2020;41 (4):496-508 [PubMed]
Wiersinga W. Joost, Rhodes Andrew, Cheng Allen C., Peacock Sharon J., Prescott Hallie C. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review JAMA 2020;324 (8):782-793 [PubMed]
Prescott Hallie C., Sussman Jeremy B., Wiersinga W. Joost Postcritical illness vulnerability Current opinion in critical care 2020;26 (5):500-507 [PubMed]
Brouwer Philip J.M., Caniels Tom G., van der Straten Karlijn, Snitselaar Jonne L., Aldon Yoann, Bangaru Sandhya, Torres Jonathan L., Okba Nisreen M.A., Claireaux Mathieu, Kerster Gius, Bentlage Arthur E.H., van Haaren Marlies M., Guerra Denise, Burger Judith A., Schermer Edith E., Verheul Kirsten D., van der Velde Niels, van der Kooi Alex, van Schooten Jelle, van Breemen Mariëlle J., Bijl Tom P.L., Sliepen Kwinten, Aartse Aafke, Derking Ronald, Bontjer Ilja, Kootstra Neeltje A., Joost Wiersinga W., Vidarsson Gestur, Haagmans Bart L., Ward Andrew B., de Bree Godelieve J., Sanders Rogier W., van Gils Marit J. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability Science 2020;369 (6504):643-650 [PubMed]
Wiersinga W. J., de Bree G. J. Re-infectie met SARS-CoV-2 Nederlands tijdschrift voor geneeskunde 2020;164 [PubMed]
Joost Wiersinga W. SARS-CoV-2 in Nederland: de kliniek van een nieuw virus Nederlands tijdschrift voor geneeskunde 2020;164 (16) [PubMed]
Schinkel Michiel, Nannan Panday Rishi S., Joost Wiersinga W., Nanayakkara Prabath W. B. Timeliness of antibiotics for patients with sepsis and septic shock Journal of thoracic disease 2020;2:S66-S71 [PubMed]
Haak Bastiaan W., Wiersinga W. Joost Uncovering hidden antimicrobial resistance patterns within the hospital microbiome Nature medicine 2020;26 (6):826-828 [PubMed]
van den Berg Fons F., van Dalen Demi, Hyoju Sanjiv K., van Santvoort Hjalmar C., Besselink Marc G., Wiersinga Willem Joost, Zaborina Olga, Boermeester Marja A., Alverdy John Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate Gut 2020 [PubMed]
Wiersinga W. Joost, Prescott Hallie C. What Is COVID-19? JAMA 2020;324 (8):816 [PubMed]

2019

Rubio Ignacio, Osuchowski Marcin F., Shankar-Hari Manu, Skirecki Tomasz, Winkler Martin Sebastian, Lachmann Gunnar, la Rosée Paul, Monneret Guillaume, Venet Fabienne, Bauer Michael, Brunkhorst Frank M., Kox Matthijs, Cavaillon Jean-Marc, Uhle Florian, Weigand Markus A., Flohé Stefanie B., Wiersinga W. Joost, Martin-Fernandez Marta, Almansa Raquel, Martin-Loeches Ignacio, Torres Antoni, Giamarellos-Bourboulis Evangelos J., Girardis Massimo, Cossarizza Andrea, Netea Mihai G., van der Poll Tom, Scherag André, Meisel Christian, Schefold Joerg C., Bermejo-Martín Jesús F. Current gaps in sepsis immunology: new opportunities for translational research Lancet infectious diseases 2019;19 (12):e422-e436 [PubMed]
Virk Harjeet Singh, Wiersinga W. Joost Current place of probiotics for VAP Critical care (London, England) 2019;23 (1):46 [PubMed]
Birnie Emma Digging for melioidosis: New insights into the epidemiology and pathophysiology 2019. 403p. ISBN 9789402815450. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga W. J. , Grobusch M. P.)
Birnie Emma, Virk Harjeet S., Savelkoel Jelmer, Spijker Rene, Bertherat Eric, Dance David A. B., Limmathurotsakul Direk, Devleesschauwer Brecht, Haagsma Juanita A., Wiersinga W. Joost Global burden of melioidosis in 2015: a systematic review and data synthesis Lancet infectious diseases 2019;19 (8):892-902 [PubMed]
Birnie Emma, van’t Hof Senne, Bijnsdorp Anne, Mansaray Yembeh, Huizenga Erdi, van der Ende Arie, Hugenholtz Floor, Grobusch Martin P., Joost Wiersinga W. Identification of burkholderia Thailandensis with novel genotypes in the soil of central Sierra Leone PLoS neglected tropical diseases 2019;13 (6) [PubMed]
Bhalodi Amira A., van Engelen Tjitske S. R., Virk Harjeet S., Wiersinga W. Joost Impact of antimicrobial therapy on the gut microbiome Journal of antimicrobial chemotherapy 2019;74 (1):i6-i15 [PubMed]
Haak Bastiaan W., Lankelma Jacqueline M., Hugenholtz Floor, Belzer Clara, de Vos Willem M., Wiersinga W. Joost Long-term impact of oral vancomycin, ciprofloxacin and metronidazole on the gut microbiota in healthy humans Journal of antimicrobial chemotherapy 2019;74 (3):782-786 [PubMed]
Birnie Emma, Savelkoel Jelmer, Reubsaet F., Roelofs Joris J. T. H., Soetekouw R., Kolkman Saskia, Cremers Anne Lia, Grobusch Martin P., Notermans Daan W., Wiersinga W. Joost, Rozemeijer Wouter, Rijkeboer Annemieke, Scholing Maarten, van Dijk K., Mascini Ellen M., van der Veen Henk, van den Bijllaardt Wouter, de Vries Maaike, Smeets Leonard C., Ott Alewijn, van Krimpen Kees, Herpers Bjorn L., Watttel-Louis G. Hanke, Waar Karola, Schwandt Noortje L. Q., Maat Ianthe, Dofferhoff Anthonius S. M., Vermeulen Joost N., van Westreenen Mireille, de Man P., Hofland Regina W., van Gorp J., Thijsen Steven, van der Velden Lieven B., Verduin Cornelis M. Melioidosis in travelers: An analysis of Dutch melioidosis registry data 1985–2018 Travel medicine and infectious disease 2019;32 [PubMed]
Limmathurotsakul Direk, Daily Frances, Bory Sotharith, Khim Gaetan, Wiersinga W. Joost, Torres Alfredo G., Dance David A. B., Currie Bart J. Melioidosis: The hazards of incomplete peer-review PLoS neglected tropical diseases 2019;13 (3):e0007123 [PubMed]
Idelevich E. A., Seifert H., Sundqvist M., Scudeller L., Amit S., Balode A., Bilozor A., Drevinek P., Kocak Tufan Z., Koraqi A., Lamy B., Mareković I., Miciuleviciene J., Müller Premru M., Pascual A., Pournaras S., Saegeman V., Schønheyder H. C., Schrenzel J., Strateva T., Tilley R., Wiersinga W. J., Zabicka D., Carmeli Y., Becker K. Microbiological diagnostics of bloodstream infections in Europe—an ESGBIES survey Clinical microbiology and infection 2019;25 (11):1399-1407 [PubMed]
Lemkes Bregtje A., Richel Olivier, Bonten Marc J., Van Der Linden Paul D., Wiersinga W. Joost Nieuwe antibiotica: Een overzicht Nederlands tijdschrift voor geneeskunde 2019;163 (9) [PubMed]
Cranendonk Duncan R. On the pathophysiology and management of cellulitis 2019. 204p. ISBN 9789463802871. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga W. J. , Prins J. M.)
Wiersinga W. J., Koopmans M. P. G., van Dissel J. T. Opkomst en dreiging van infectieziekten Nederlands tijdschrift voor geneeskunde 2019;163 (51) [PubMed]
Zingarelli Basilia, Coopersmith Craig M., Drechsler Susanne, Efron Philip, Marshall John C., Moldawer Lyle, Wiersinga W. Joost, Xiao Xianzhong, Osuchowski Marcin F., Thiemermann Christoph Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints Shock (Augusta, Ga.) 2019;51 (1):10-22 [PubMed]
Birnie Emma, Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., Budding Andries E., de Vos Alex F., van der Poll Tom, Wiersinga W. Joost Role of Toll-Like Receptor 5 (TLR5) in Experimental Melioidosis Infection and immunity 2019;87 (8) [PubMed]
Haak Bastiaan W., Wiersinga W. Joost The differing roles of lactobacilli in critical illness Nature medicine 2019;25 (11):1651-1653 [PubMed]
Cranendonk Duncan R., Hugenholtz Floor, Prins Jan M., Savelkoul Paul H. M., Budding Andries E., Wiersinga W. Joost, Hoepelman Andy I. M., Oosterheert Jan Jelrik, van Agtmael Michiel A., Branger Judith, Brinkman Kees, Lauw Fanny N., Pijlman Annemarie H., Sankatsing Sanjay U. C., Soetekouw Robin, Veenstra Jan, de Vries Peter J. The skin microbiota in patients hospitalized for cellulitis and association with outcome Clinical infectious diseases 2019;68 (8):1292-1299 [PubMed]
Birnie Emma, Claushuis Theodora A. M., Koh Gavin C. K. W., Limmathurotsakul Direk, Day Nicholas P. J., Roelofs Joris J. T. H., Ware Jerry, Hou Baidong, de Vos Alex F., van der Poll Tom, van't Veer Cornelis, Wiersinga W. Joost Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis) Journal of infectious diseases 2019;219 (4):648-659 [PubMed]

2018

de Jong Hanna K., Parry Chris M., van der Vaart Thomas W., Kager Liesbeth M., van den Ende Stannie J., Maude Rapeephan R., Wijedoru Lalith, Ghose Aniruddha, Hassan Mohammed U., Hossain Mohammed A., Dondorp Arjan M., Baker Steve, Faiz M. Abul, Meijers Joost C. M., Wiersinga W. Joost Activation of coagulation and endothelium with concurrent impairment of anticoagulant mechanisms in patients with typhoid fever Journal of infection 2018;77 (1):60-67 [PubMed]
van Engelen Tjitske S. R., Wiersinga Willem Joost, Scicluna Brendon P., van der Poll Tom Biomarkers in Sepsis Critical care clinics 2018;34 (1):139-+ [PubMed]
Osuchowski Marcin F., Ayala Alfred, Bahrami Soheyl, Bauer Michael, Boros Mihaly, Cavaillon Jean-Marc, Chaudry Irshad H., Coopersmith Craig M., Deutschman Clifford, Drechsler Susanne, Efron Philip, Frostell Claes, Fritsch Gerhard, Gozdzik Waldemar, Hellman Judith, Huber-Lang Markus, Inoue Shigeaki, Knapp Sylvia, Kozlov Andrey V., Libert Claude, Marshall John C., Moldawer Lyle L., Radermacher Peter, Redl Heinz, Remick Daniel G., Singer Mervyn, Thiemermann Christoph, Wang Ping, Wiersinga W. Joost, Xiao Xianzhong, Zingarelli Basilia Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis (Infection, (2018), 46, 5, (687-691), 10.1007/s15010-018-1183-8) Infection 2018;46 (5):745-747 [PubMed]
Schuurman A. R., Bos S. A., de Wit K., de Graaf R., Wiersinga W. J. Een dag uit het leven van de zaalarts interne geneeskunde Nederlands tijdschrift voor geneeskunde 2018;161:D2480 [PubMed]
Harris Vanessa C., Haak Bastiaan W., Handley Scott A., Jiang Baoming, Velasquez Daniel E., Hykes Barry L., Droit Lindsay, Berbers Guy A. M., Kemper Elles Marleen, van Leeuwen Ester M. M., Boele van Hensbroek Michael, Wiersinga Willem Joost Effect of Antibiotic-Mediated Microbiome Modulation on Rotavirus Vaccine Immunogenicity: A Human, Randomized-Control Proof-of-Concept Trial Cell host & microbe 2018;24 (2):197-207.e4 [PubMed]
Hatleberg Camilla I., Ryom Lene, el-Sadr Wafaa, Mocroft Amanda, Reiss Peter, de Wit Stephane, Dabis Francois, Pradier Christian, D’Arminio Monforte Antonella, Kovari Helen, Law Matthew, Lundgren Jens D., Sabin Caroline A., Calvo G., Bonnet F., Kirk O., Morfeldt L., Weber R., Lind-Thomsen A., Salbøl Brandt R., Hillebreght M., Zaheri S., Wit Fwnm, Scherrer A., Schöni-Affolter F., Rickenbach M., Tavelli A., Fanti I., Leleux O., Mourali J., le Marec F., Boerg E., Thulin E., Sundström A., Bartsch G., Thompsen G., Necsoi C., Delforge M., Prins J. M., Kuijpers T. W., Scherpbier H. J., Godfried M. H., Geerlings S. E., Bos J. C., Wiersinga W. J., Hovius J. W., Zaaijer H. L., Schinkel C. J., Stelma F. F., Ang C. W. Gender differences in the use of cardiovascular interventions in HIV-positive persons; the D:A:D study Journal of the International AIDS Society 2018;21 (3) [PubMed]
Savelkoel Jelmer, Claushuis Theodora A. M., van Engelen Tjitske S. R., Scheres Luuk J. J., Wiersinga W. Joost Global impact of World Sepsis Day on digital awareness of sepsis: An evaluation using Google Trends Critical care (London, England) 2018;22 (1) [PubMed]
Wiersinga W. Joost, Seymour Christopher W. Handbook of sepsis Springer International Publishing AG; 2018. 253p. ISBN 9783319735054
Boerekamps Anne, Newsum Astrid M., Smit Colette, Arends Joop E., Richter Clemens, Reiss Peter, Rijnders Bart J. A., Brinkman Kees, van der Valk Marc, Study group members AMC , Geerlings Suzanne E., Godfried Mieke H., Goorhuis Abraham, Hovius Joppe W. R., van der Meer Johannes T. M., Kuijpers Taco W., Nellen Francisca J. B., van der Poll Tom, Prins Jan M., van Vugt H. J. M. , Wiersinga Willem J., Wit Ferdinand W. N. M. High treatment uptake in HIV/HCV-coinfected patients after unrestricted access to direct-acting antivirals in the Netherlands Clinical infectious diseases 2018;66 (9):1352-1359 [PubMed]
Jacobs Max C, Wiersinga W Joost Interleukin-34: A New Player in the Sepsis Arena Critical care medicine 2018;46 (6):1032-1033 [PubMed]
Wiersinga W. J., Bonten M. J., Boersma W. G., Jonkers R. E., Aleva R. M., Kullberg B. J., Schouten J. A., Degener J. E., van de Garde E. M. W., Verheij T. J., Sachs A. P. E., Prins J. M. Management of community-acquired pneumonia in adults: 2016 guideline update from the Dutch Working Party on Antibiotic Policy (SWAB) and Dutch Association of Chest Physicians (NVALT) Netherlands journal of medicine 2018;76 (1):4-13 [PubMed]
Smolders E. J., Smit C., de Kanter C. T. M. M., Dofferhoff A. S. M., Arends J. E., Brinkman K., Rijnders B., van der Valk M., Reiss P., Burger D. M., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Wiersinga W. J., Goorhuis A., Hovius J. W., Bijsterveld M. A. H., van Eden J., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Weijsenfeld A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., Hage de Looff L., Wintermans B., Veenemans J., Pronk M. J. H., Ammerlaan H. S. M., de Munnik E. S., Langebeek N., van Wijk M., Vandenbroucke-Grauls C. M. J. E. Management of drug interactions with direct-acting antivirals in Dutch HIV/hepatitis C virus-coinfected patients: adequate but not perfect HIV medicine 2018;19 (3):216-226 [PubMed]
Wiersinga W. Joost, Virk Harjeet S., Torres Alfredo G., Currie Bart J., Peacock Sharon J., Dance David A. B., Limmathurotsakul Direk Melioidosis Nature reviews. Disease primers 2018;4:17107 [PubMed]
Osuchowski Marcin F, Ayala Alfred, Bahrami Soheyl, Bauer Michael, Boros Mihaly, Cavaillon Jean-Marc, Chaudry Irshad H, Coopersmith Craig M, Deutschman Clifford, Drechsler Susanne, Efron Philip, Frostell Claes, Fritsch Gerhard, Gozdzik Waldemar, Hellman Judith, Huber-Lang Markus, Inoue Shigeaki, Knapp Sylvia, Kozlov Andrey V, Libert Claude, Marshall John C, Moldawer Lyle L, Radermacher Peter, Redl Heinz, Remick Daniel G, Singer Mervyn, Thiemermann Christoph, Wang Ping, Wiersinga Willem Joost, Xiao Xianzhong, Zingarelli Basilia Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis Intensive Care Medicine Experimental 2018;6 (1):26 [PubMed]
Osuchowski Marcin F., Ayala Alfred, Bahrami Soheyl, Bauer Michael, Boros Mihaly, Cavaillon Jean-Marc, Chaudry Irshad H., Coopersmith Craig M., Deutschman Clifford, Drechsler Susanne, Efron Philip, Frostell Claes, Fritsch Gerhard, Gozdzik Waldemar, Hellman Judith, Huber-Lang Markus, Inoue Shigeaki, Knapp Sylvia, Kozlov Andrey V., Libert Claude, Marshall John C., Moldawer Lyle L., Radermacher Peter, Redl Heinz, Remick Daniel G., Singer Mervyn, Thiemermann Christoph, Wang Ping, Wiersinga W. Joost, Xiao Xianzhong, Zingarelli Basilia Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis Infection 2018;46 (5):687-691 [PubMed]
Osuchowski Marcin F., Ayala Alfred, Bahrami Soheyl, Bauer Michael, Boros Mihaly, Cavaillon Jean-Marc, Chaudry Irshad H., Coopersmith Craig M., Deutschman Clifford S., Drechsler Susanne, Efron Philip, Frostell Claes, Fritsch Gerhard, Gozdzik Waldemar, Hellman Judith, Huber-Lang Markus, Inoue Shigeaki, Knapp Sylvia, Kozlov Andrey V., Libert Claude, Marshall John C., Moldawer Lyle L., Radermacher Peter, Redl Heinz, Remick Daniel G., Singer Mervyn, Thiemermann Christoph, Wang Ping, Wiersinga W. Joost, Xiao Xianzhong, Zingarelli Basilia Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis Shock (Augusta, Ga.) 2018;50 (4):377-380 [PubMed]
van Engelen Tjitske S. R., Wiersinga W. Joost, van der Poll Tom Pathogenesis of sepsisin: Handbook of Sepsis. Springer International Publishing; 2018. p. 31-43, ISBN 9783319735054
De Francesco Davide, Verboeket Sebastiaan O, Underwood Jonathan, Bagkeris Emmanouil , Wit Ferdinand W, Mallon Patrick W G, Winston Alan, Reiss Peter, Sabin Caroline A, Study group members AMC , Reiss P. , Wit F. W. N. M., Kooij K. W., van Zoest R. A. , Verheij E. , Verboeket Sebastiaan O., Prins M. , Kootstra N. A., Harskamp-Holwerda A. M. , Maurer Irma, Mangas Ruiz M. M., Boeser-Nunnink B. D. M. , Geerlings S. E. , Goorhuis A. , Hovius J. W. R. , Nellen F. J. B. , van der Poll Tom, Prins J. M. , Wiersinga W. J. , van Vugt M. , de Bree G. J. , Postema P. G. , Bisschop P. H. L. T., Serlie M. J. M. , Dekker E. , van der Velde N. , Willemsen J. M. R., Vogt L. , Portegies P. , Schmand B. A. , Geurtsen G. J. , Verbraak F. D. , Visser I. , Nieuwkerk P. T. , Majoie C. B. L. M. , Caan M. W. A. , van Lunsen H. W. , van den Born B. J. H. , Stroes E. S. G. Patterns of co-occurring comorbidities in people living with HIV Open forum infectious diseases 2018;5 (11):ofy272 [PubMed]
Wiersinga W. Joost, Seymour Christopher W. Preface Handbook of Sepsis 2018:v
Wiersinga W. Joost, Seymour Christopher W. Preface Handbook of Sepsis 2018:v
Wiersinga W. Joost, Seymour Christopher W. Preface Handbook of Sepsis 2018:v
Harris Vanessa, Ali Asad, Fuentes Susana, Korpela Katri, Kazi Momin, Tate Jacqueline, Parashar Umesh, Wiersinga W. Joost, Giaquinto Carlo, de Weerth Carolina, de Vos Willem M. Rotavirus Vaccine Response Correlates with the Infant Gut Microbiota Composition in Pakistan Gut microbes 2018;9 (2):93-101 [PubMed]
Wolff Nora Suzanne, Hugenholtz Floor, Wiersinga Willem Joost The emerging role of the microbiota in the ICU Critical care (London, England) 2018;22 (1) [PubMed]
Haak Bastiaan W., Prescott Hallie C., Wiersinga W. Joost Therapeutic potential of the gut microbiota in the prevention and treatment of sepsis Frontiers in immunology 2018;9 (SEP) [PubMed]
Harris Vanessa C. The role of the intestinal microbiome in rotavirus vaccine immunogenicity: exploration from correlation to causation 2018. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga W. J., Boele van Hensbroek M.; Co-supervisors: van der Poll T., Giaquinto C.)
Rello J., van Engelen T. S. R., Alp E., Calandra T., Cattoir V., Kern W. V., Netea M. G., Nseir S., Opal S. M., van de Veerdonk F. L., Wilcox M. H., Wiersinga W. J. Towards precision medicine in sepsis: a position paper from the European Society of Clinical Microbiology and Infectious Diseases Clinical microbiology and infection 2018;24 (12):1264-1272 [PubMed]

2017

Lankelma Jacqueline M., Cranendonk Duncan R., Belzer Clara, de Vos Alex F., de Vos Willem M., van der Poll Tom, Wiersinga W. Joost Antibiotic-induced gut microbiota disruption during human endotoxemia: a randomised controlled study Gut 2017;66 (9):1623-1630 [PubMed]
Cranendonk D. R., Lavrijsen A. P. M., Prins J. M., Wiersinga W. J. Cellulitis: current insights into pathophysiology and clinical management Netherlands journal of medicine 2017;75 (9):366-378 [PubMed]
Cranendonk Duncan R., van Vught Lonneke A., Wiewel Maryse A., Cremer Olaf L., Horn Janneke, Bonten Marc J., Schultz Marcus J., van der Poll Tom, Wiersinga W. Joost Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care JAMA dermatology 2017;153 (6):578-582 [PubMed]
Lankelma Jacqueline M., van Vught Lonneke A., Belzer Clara, Schultz Marcus J., van der Poll Tom, de Vos Willem M., Wiersinga W. Joost Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study Intensive care medicine 2017;43 (1):59-68 [PubMed]
Malotaux J., Wiersinga W. J., Geerlings S. E. De optimale duur van antibiotische therapie Nederlands tijdschrift voor geneeskunde 2017;161:D1891 [PubMed]
Weehuizen Tassili A. F., Birnie Emma, Ferwerda Bart, Roelofs Joris J. T. H., de Vos Alex F., Grobusch Martin P., Wiersinga W. Joost Differences in Inflammation Patterns Induced by African and Asian Burkholderia pseudomallei Isolates in Mice American journal of tropical medicine and hygiene 2017;96 (6):1365-1369 [PubMed]
Helbok Raimund, Wiersinga W. Joost Editorial introductions Current opinion in critical care 2017;23 (2):v
de Jong Hanna K., Garcia-Laorden Maria Isabel, Hoogendijk Arie J., Parry Christopher M., Maude Rapeephan R., Dondorp Arjen M., Faiz Mohammed Abul, van der Poll Tom, Wiersinga Willem Joost Expression of intra- and extracellular granzymes in patients with typhoid fever PLoS neglected tropical diseases 2017;11 (7):e0005823 [PubMed]
Jacobs Max C., Haak Bastiaan W., Hugenholtz Floor, Wiersinga W. Joost Gut microbiota and host defense in critical illness Current opinion in critical care 2017;23 (4):257-263 [PubMed]
Iapichino Gaetano, Lankelma Jacqueline M., Wiersinga W. Joost Gut microbiota disruption in critically ill patients : Discussion on "Critically ill patients demonstrate large interpersonal variation of intestinal microbiota dysregulation: a pilot study" Intensive care medicine 2017;43 (5):718-719 [PubMed]
Bartelsman M., Joore I. K., van Bergen J. E., Hogewoning A. A., Zuure F. R., van Veen M. G., Deug F., Heidenrijk M., Prins J. M., Prins M. [= Maria], Smit P. J., van der Valk M., Reiss P., de Bree G. J., Hoornenborg E., Davidovich U., Geerlings S. E., Oomen A., van sighem A., Zuilhof W., Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Berkhout B., Berretty B., Bezemer D., Blok W. L., Bomers M., Boucher C. A. B., Brokking W., Burger D., Brinkman K., de Bruin M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., van der Helm J. J., Hovius J. W., Kootstra N. A., van der Meer J. T., Nellen F. J., Pasternak A. O., van der Poll T., van Rooijen M. S., de Vries H. J., van Vugt M., Wiersinga W. J., Wit F. W. HIV testing week 2015: lowering barriers for HIV testing among high-risk groups in Amsterdam BMC infectious diseases 2017;17 (1):529 [PubMed]
Birnie Emma, Koh Gavin C. K. W., Löwenberg Ester C., Meijers Joost C. M., Maude Rapeephan R., Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga W. Joost Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis PLoS neglected tropical diseases 2017;11 (3) [PubMed]
Haak Bastiaan W., Levi Marcel, Wiersinga W. Joost Microbiota-targeted therapies on the intensive care unit Current opinion in critical care 2017;23 (2):167-174 [PubMed]
Lankelma Jacqueline M., Wagemakers Alex, Birnie Emma, Haak Bastiaan W., Trentelman Jos J. A., Weehuizen Tassili A. F., Ersöz Jasmin, Roelofs Joris J. T. H., Hovius Joppe W., Wiersinga W. Joost, Bins Adriaan D. Rapid DNA vaccination against Burkholderia pseudomallei flagellin by tattoo or intranasal application Virulence 2017;8 (8):1683-1694 [PubMed]
Lankelma Jacqueline M., Schuijt Tim J., Wiersinga W. Joost Reply to letter to the editor of Gut by Dickson and Cox Gut 2017;66 (3):556 [PubMed]
Wiersinga W. J., van Zanten A. R. H., Kaasjager K. A., van der Poll T. Sepsis: nieuwe inzichten, nieuwe definitie Nederlands tijdschrift voor geneeskunde 2017;161:D1551 [PubMed]
Harmon Matthew B. A., Wiewel Maryse A., Wiersinga W. Joost, Juffermans Nicole P. Should we assume that hypothermia is a dysfunction in sepsis? Authors' Response Critical care medicine 2017;21 [PubMed]
Harris Vanessa C., Armah George, Fuentes Susana, Korpela Katri E., Parashar Umesh, Victor John C., Tate Jacqueline, de Weerth Carolina, Giaquinto Carlo, Wiersinga Willem Joost, Lewis Kristen D. C., de Vos Willem M. Significant Correlation Between the Infant Gut Microbiome and Rotavirus Vaccine Response in Rural Ghana Journal of infectious diseases 2017;215 (1):34-41 [PubMed]
Rhodes Andrew, Evans Laura E., Alhazzani Waleed, Levy Mitchell M., Antonelli Massimo, Ferrer Ricard, Kumar Anand, Sevransky Jonathan E., Sprung Charles L., Nunnally Mark E., Rochwerg Bram, Rubenfeld Gordon D., Angus Derek C., Annane Djillali, Beale Richard J., Bellinghan Geoffrey J., Bernard Gordon R., Chiche Jean-Daniel, Coopersmith Craig, de Backer Daniel P., French Craig J., Fujishima Seitaro, Gerlach Herwig, Hidalgo Jorge Luis, Hollenberg Steven M., Jones Alan E., Karnad Dilip R., Kleinpell Ruth M., Koh Younsuk, Lisboa Thiago Costa, Machado Flavia R., Marini John J., Marshall John C., Mazuski John E., McIntyre Lauralyn A., McLean Anthony S., Mehta Sangeeta, Moreno Rui P., Myburgh John, Navalesi Paolo, Nishida Osamu, Osborn Tiffany M., Perner Anders, Plunkett Colleen M., Ranieri Marco, Schorr Christa A., Seckel Maureen A., Seymour Christopher W., Shieh Lisa, Shukri Khalid A., Simpson Steven Q., Singer Mervyn, Thompson B. Taylor, Townsend Sean R., van der Poll Thomas, Vincent Jean-Louis, Wiersinga W. Joost, Zimmerman Janice L., Dellinger R. Phillip Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Intensive care medicine 2017;43 (3):304-377 [PubMed]
Rhodes Andrew, Evans Laura E., Alhazzani Waleed, Levy Mitchell M., Antonelli Massimo, Ferrer Ricard, Kumar Anand, Sevransky Jonathan E., Sprung Charles L., Nunnally Mark E., Rochwerg Bram, Rubenfeld Gordon D., Angus Derek C., Annane Djillali, Beale Richard J., Bellinghan Geoffrey J., Bernard Gordon R., Chiche Jean-Daniel, Coopersmith Craig, de Backer Daniel P., French Craig J., Fujishima Seitaro, Gerlach Herwig, Hidalgo Jorge Luis, Hollenberg Steven M., Jones Alan E., Karnad Dilip R., Kleinpell Ruth M., Koh Younsuck, Lisboa Thiago Costa, Machado Flavia R., Marini John J., Marshall John C., Mazuski John E., McIntyre Lauralyn A., McLean Anthony S., Mehta Sangeeta, Moreno Rui P., Myburgh John, Navalesi Paolo, Nishida Osamu, Osborn Tiffany M., Perner Anders, Plunkett Colleen M., Ranieri Marco, Schorr Christa A., Seckel Maureen A., Seymour Christopher W., Shieh Lisa, Shukri Khalid A., Simpson Steven Q., Singer Mervyn, Thompson B. Taylor, Townsend Sean R., van der Poll Thomas, Vincent Jean-Louis, Wiersinga W. Joost, Zimmerman Janice L., Dellinger R. Phillip Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Critical care medicine 2017;45 (3):486-552 [PubMed]
Wiersinga W. Joost The gut microbiome takes center stage in critical care Current opinion in critical care 2017;23 (2):140-142 [PubMed]
Lankelma Jacqueline M., Birnie Emma, Weehuizen Tassili A. F., Scicluna Brendon P., Belzer Clara, Houtkooper Riekelt H., Roelofs Joris J. T. H., de Vos Alex F., van der Poll Tom, Budding Andries E., Wiersinga W. Joost The gut microbiota as a modulator of innate immunity during melioidosis PLoS neglected tropical diseases 2017;11 (4):e0005548 [PubMed]
Harris Vanessa C., Haak Bastiaan W., Boele van Hensbroek Michaël, Wiersinga Willem J. The Intestinal Microbiome in Infectious Diseases: The Clinical Relevance of a Rapidly Emerging Field Open forum infectious diseases 2017;4 (3):ofx144 [PubMed]
Haak Bastiaan W., Wiersinga W. Joost The role of the gut microbiota in sepsis lancet. Gastroenterology & hepatology 2017;2 (2):135-143 [PubMed]
Lankelma Jacqueline M. The role of the intestinal microbiota in pneumonia and sepsis 2017. 242p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Wiersinga W. J.)
Peters Anna L., van Hezel Maike E., Klanderman Robert B., Tuip-de Boer Anita M., Wiersinga W. Joost, van der Spek Anne H., van Bruggen Robin, de Korte Dirk, Juffermans Nicole P., Vlaar Alexander P. J. Transfusion of 35-day-stored red blood cells does not alter lipopolysaccharide tolerance during human endotoxemia Transfusion 2017;57 (6):1359-1368 [PubMed]

2016

Lankelma Jacqueline M., Belzer Clara, Hoogendijk Arie J., de Vos Alex F., de Vos Willem M., van der Poll Tom, Wiersinga W. Joost Antibiotic-Induced Gut Microbiota Disruption Decreases TNF-alpha Release by Mononuclear Cells in Healthy Adults Clinical and translational gastroenterology 2016;7 (8):e186 [PubMed]
Maude Rapeephan R., Ghose Aniruddha, Samad Rasheda, de Jong Hanna K., Fukushima Masako, Wijedoru Lalith, Hassan Mahtab Uddin, Hossain Md Amir, Karim Md Rezaul, Sayeed Abdullah Abu, van den Ende Stannie, Pal Sujat, Zahed A. S. M., Rahman Wahid, Karnain Rifat, Islam Rezina, Tran Dung Thi Ngoc, Ha Tuyen Thanh, Pham Anh Hong, Campbell James I., van Doorn H. Rogier, Maude Richard J., van der Poll Tom, Wiersinga W. Joost, Day Nicholas P. J., Baker Stephen, Dondorp Arjen M., Parry Christopher M., Faiz Md Abul A prospective study of the importance of enteric fever as a cause of non-malarial febrile illness in patients admitted to Chittagong Medical College Hospital, Bangladesh BMC infectious diseases 2016;16 (1):567 [PubMed]
Kooij Katherine W., Wit Ferdinand W. N. M., Booiman Thijs, van der Valk Marc, Schim van der Loeff Maarten F., Kootstra Neeltje A., Reiss Peter, Schouten J., van Zoest R. A., Verheij E., Elsenga B. C., Prins M., Martens M., Moll S., Berkel J., Totté M., Visser G. R., May L., Kovalev S., Newsum A., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Vugt M., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., van der Velde N., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., Verbraak F. D., Demirkaya N., Nieuwkerk P. T., Langebeek N., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cigarette Smoking and Inflammation, Monocyte Activation, and Coagulation in HIV-Infected Individuals Receiving Antiretroviral Therapy, Compared With Uninfected Individuals Journal of infectious diseases 2016;214 (12):1817-1821 [PubMed]
Mocroft Amanda, Lundgren Jens D., Ross Michael, Fux Christoph A., Reiss Peter, Moranne Olivier, Morlat Philippe, Monforte Antonella d'Arminio, Kirk Ole, Ryom Lene, Steering D., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Ryom L., Hatleberg C. I., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Bojesen A., Grevsen A. L., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E. Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study Lancet HIV 2016;3 (1):e23-e32 [PubMed]
Schouten Judith, Su Tanja, Wit Ferdinand W., Kootstra Neeltje A., Caan Matthan W. A., Geurtsen Gert J., Schmand Ben A., Stolte Ineke G., Prins Maria, Majoie Charles B., Portegies Peter, Reiss Peter, van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Gras L. A. J., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Determinants of reduced cognitive performance in HIV-1-infected middle-aged men on combination antiretroviral therapy AIDS (London, England) 2016;30 (7):1027-1038 [PubMed]
Op de Coul Eline L. M., van Sighem Ard, Brinkman Kees, van Benthem Birgit H., van der Ende Marchina E., Geerlings Suzanne, Reiss Peter, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Westerman A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., Hage de Looff L., Versteeg D., Pronk M. J. H., Ammerlaan H. S. M., Korsten-Vorstermans E. M. H. M., de Munnik E. S., Jansz A. R., Tjhie J., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E. Factors associated with presenting late or with advanced HIV disease in the Netherlands, 1996-2014: results from a national observational cohort BMJ open 2016;6 (1):e009688 [PubMed]
Harris Vanessa C., Wiersinga W. J. Joost Het microbioom: hype of écht belangrijk? Nederlands tijdschrift voor geneeskunde 2016;160:D110 [PubMed]
van Zoest Rosan A., Wit Ferdinand W., Kooij Katherine W., van der Valk Marc, Schouten Judith, Kootstra Neeltje A., Wiersinga W. Joost, Prins Maria, van den Born Bert-Jan H., Reiss Peter Higher Prevalence of Hypertension in HIV-1-Infected Patients on Combination Antiretroviral Therapy Is Associated With Changes in Body Composition and Prior Stavudine Exposure Clinical infectious diseases 2016;63 (2):205-213 [PubMed]
Demirkaya Nazli, Wit Ferdinand W. N. M., van den Berg Thomas J. T. P., Kooij Katherine W., Prins Maria, Schlingemann Reinier O., Abramoff Michael D., Reiss Peter, Verbraak Frank D., van der Valk M., Schouten J. [=Judith], van Zoest R. A., Elsenga B. C., Martens M., Moll S., Berkel J., Totté M., Visser G. R., Kovalev S., Kootstra N. A., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study Investigative ophthalmology & visual science 2016;57 (3):1388-1397 [PubMed]
Kooij Katherine W., Wit Ferdinand W. N. M., Schouten Judith, van der Valk Marc, Godfried Mieke H., Stolte Ineke G., Prins Maria, Falutz Julian, Reiss Peter, van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Hillebregt M. M. J., Gras L. A. J., Ruijs Y. M. C., Benschop D. P., Kootstra N. A., Harskamp-Holwerda A. M., Maurer I., Ruiz M. M. Mangas, Girigorie A. F., van Leeuwen E., Janssen F. R., Heidenrijk M., Schrijver J. H. N., Zikkenheiner W., Wezel M., Jansen-Kok C. S. M., Geerlings S. E., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J. HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls AIDS (London, England) 2016;30 (2):241-250 [PubMed]
Weehuizen Tassili A. F. Host-pathogen interactions during melioidosis. When the bug meets its host 2016. 303p. ISBN 9789461698865. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Wiersinga W. J.)
Wiewel Maryse A., Harmon Matthew B., van Vught Lonneke A., Scicluna Brendon P., Hoogendijk Arie J., Horn Janneke, Zwinderman Aeilko H., Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom, Juffermans Nicole P., Wiersinga W. Joost Risk factors, host response and outcome of hypothermic sepsis Critical care (London, England) 2016;20 (1):328 [PubMed]
Achhra A. C., Mocroft A., Reiss P., Sabin C., Ryom L., de Wit S., Smith C. J., d'Arminio Monforte A., Phillips A., Weber R., Lundgren J., Law M. G., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Hatleberg C. I., Sabin C. A., Kamara D., Smith C., Bojesen A., Nielsen J., Raben D., Lundgren J. D., Salbøl Brandt R., Rickenbach M., Fanti I., Krum E., Hillebregt M., Geffard S., Sundström A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Short-term weight gain after antiretroviral therapy initiation and subsequent risk of cardiovascular disease and diabetes: the D:A:D study HIV medicine 2016;17 (4):255-268 [PubMed]
Cobos Jiménez Viviana, Wit Ferdinand W. N. M., Joerink Maaike, Maurer Irma, Harskamp Agnes M., Schouten Judith, Prins Maria, van Leeuwen Ester M. M., Booiman Thijs, Deeks Steven G., Reiss Peter, Kootstra Neeltje A., van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Martens M., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., Nellen F. J. B., van der Meer J. T. M., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment Journal of infectious diseases 2016;214 (2):216-225 [PubMed]
Schuijt Tim J., Lankelma Jacqueline M., Scicluna Brendon P., de Sousa E Melo Felipe, Roelofs Joris J. T. H., de Boer J. Daan, Hoogendijk Arjan J., de Beer Regina, de Vos Alex, Belzer Clara, de Vos Willem M., van der Poll Tom, Wiersinga W. Joost The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia Gut 2016;65 (4):575-583 [PubMed]
Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., de Boer Onno J., Roelofs Joris J. T. H., Day Nicholas P., Gram Hermann, de Vos Alex F., Wiersinga W. Joost Therapeutic Administration of a Monoclonal Anti-Il-1β Antibody Protects Against Experimental Melioidosis Shock (Augusta, Ga.) 2016;46 (5):566-574 [PubMed]
Weehuizen Tassili A. F., Hommes Tijmen J., Lankelma Jacqueline M., de Jong Hanna K., Roelofs Joris J. T. H., de Vos Alex F., Colonna Marco, van der Poll Tom, Wiersinga W. Joost Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis PLoS neglected tropical diseases 2016;10 (6):e0004747 [PubMed]
Rokx C., Gras L., van de Vijver Damc, Verbon A., Rijnders Bja, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Lowe S., Oude Lashof A., Posthouwer D., Pronk M. J. H., Ammerlaan H. S. M., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., van Gorp E. C. M., van der Feltz M., Driessen G. J. A., van Rossum A. M. C., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Bouwhuis J. W., Soetekouw R., ten Kate R. W., Kroon F. P., van Dissel J. T., Arend S. M., de Boer M. G. J., Jolink H., Vollaard A. M. Virological responses to lamivudine or emtricitabine when combined with tenofovir and a protease inhibitor in treatment-naïve HIV-1-infected patients in the Dutch AIDS Therapy Evaluation in the Netherlands (ATHENA) cohort HIV medicine 2016;17 (8):571-580 [PubMed]
Wiersinga W. Joost, Levi Marcel What Other Industries Can Learn From Health Care JAMA internal medicine 2016;176 (4):425-426 [PubMed]

2015

Cain Lauren E., Phillips Andrew, Olson Ashley, Sabin Caroline, Jose Sophie, Justice Amy, Tate Janet, Logan Roger, Robins James M., Sterne Jonathan A. C., van Sighem Ard, Reiss Peter, Young James, Fehr Jan, Touloumi Giota, Paparizos Vasilis, Esteve Anna, Casabona Jordi, Monge Susana, Moreno Santiago, Seng Rémonie, Meyer Laurence, Pérez-Hoyos Santiago, Muga Roberto, Dabis François, Vandenhende Marie-Anne, Abgrall Sophie, Costagliola Dominique, Hernán Miguel A., Ainsworth Jonathan, Anderson Jane, Babiker Abdel, Delpech Valerie, Gras L. A. J., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J. Boosted Lopinavir- Versus Boosted Atazanavir-Containing Regimens and Immunologic, Virologic, and Clinical Outcomes: A Prospective Study of HIV-Infected Individuals in High-Income Countries Clinical infectious diseases 2015;60 (8):1262-1268 [PubMed]
Bruyand Mathias, Ryom Lene, Shepherd Leah, Fatkenheuer Gerd, Grulich Andrew, Reiss Peter, de Wit Stéphane, D Arminio Monforte Antonella, Furrer Hansjakob, Pradier Christian, Lundgren Jens, Sabin Caroline, Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Ryom L., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Mansfeld M., Nielsen J., Raben D., Lundgren J. D., Salbøl Brandt R., Rickenbach M., Fanti I., Krum E., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Cancer risk and use of protease inhibitor or nonnucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy: the D: A: D study JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2015;68 (5):568-577 [PubMed]
Gras Luuk, de Wolf Frank, Smit Colette, Prins Maria, van der Meer Jan T. M., Vanhommerig Joost W., Zwinderman Aeilko H., Schinkel Janke, Geskus Ronald B., Kuijpers T. W., Scherpbier H. J., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Lowe S., Oude Lashof A., Posthouwer D., Pronk M. J. H., Ammerlaan H. S. M., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., Verbon A., Rijnders B. J. A., van Gorp E. C. M., van der Feltz M., Driessen G. J. A., van Rossum A. M. C., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld H. P., Bouwhuis J. W., Soetekouw R., ten Kate R. W., Kroon F. P., van Dissel J. T., Arend S. M. Changes in HIV RNA and CD4 cell count after acute HCV infection in chronically HIV-infected individuals JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2015;68 (5):536-542 [PubMed]
Wiersinga W. Joost, Birnie Emma, Weehuizen Tassili A. F., Alabi Abraham S., Huson Michaëla A. M., Huis In 't Veld Robert A. G., Mabala Harry K., Adzoda Gregoire K., Raczynski-Henk Yannick, Esen Meral, Lell Bertrand, Kremsner Peter G., Visser Caroline E., Wuthiekanun Vanaporn, Peacock Sharon J., van der Ende Arie, Limmathurotsakul Direk, Grobusch Martin P. Clinical, environmental, and serologic surveillance studies of melioidosis in Gabon, 2012-2013 Emerging infectious diseases 2015;21 (1):40-47 [PubMed]
Lodi Sara, Phillips Andrew, Logan Roger, Olson Ashley, Costagliola Dominique, Abgrall Sophie, van Sighem Ard, Reiss Peter, Miró José M., Ferrer Elena, Justice Amy, Gandhi Neel, Bucher Heiner C., Furrer Hansjakob, Moreno Santiago, Monge Susana, Touloumi Giota, Pantazis Nikos, Sterne Jonathan, Young Jessica G., Meyer Laurence, Seng Rémonie, Dabis Francois, Vandehende Marie-Anne, Pérez-Hoyos Santiago, Jarrín Inma, Jose Sophie, Sabin Caroline, Hernán Miguel A., Ainsworth J., Anderson J., Babiker A., Delpech V., Prins J. M., Kuijpers T. W., Godfried M. H., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Gras L. A. J., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M. Comparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study Lancet HIV 2015;2 (8):e335-e343 [PubMed]
Mocroft Amanda, Lundgren Jens D., Ross Michael, Law Matthew, Reiss Peter, Kirk Ole, Smith Colette, Wentworth Deborah, Neuhaus Jacqueline, Fux Christoph A., Moranne Olivier, Morlat Phillipe, Johnson Margaret A., Ryom Lene, Lundgren J. D., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Sabin C. A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E., Grijsen M., Lange J., van der Horst C., Frank M. Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study PLoS medicine 2015;12 (3):e1001809 [PubMed]
de Jong H. K., Koh G. C. K. W., Bulder I., Stephan F., Wiersinga W. J., Zeerleder S. S. Diabetes-independent increase of factor VII-activating protease activation in patients with Gram-negative sepsis (melioidosis) Journal of thrombosis and haemostasis 2015;13 (1):41-46 [PubMed]
Weehuizen Tassili A. F., Prior Joann L., van der Vaart Thomas W., Ngugi Sarah A., Nepogodiev Sergey A., Field Robert A., Kager Liesbeth M., van 't Veer Cornelis, de Vos Alex F., Wiersinga W. Joost Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models PLoS ONE 2015;10 (12):e0145397 [PubMed]
Schoffelen Annelot F., Smit Colette, van Lelyveld Steven F. L., Vogt Liffert, Bauer Martijn P., Reiss Peter, Hoepelman Andy I. M., Barth Roos E., Prins J. M., Kuijpsers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Westerman A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., Sabbe L., Goudswaard J., Pronk M. J. H., Ammerlaan H. S. M., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E., Gras L. A. J. Diminished impact of ethnicity as a risk factor for chronic kidney disease in the current HIV treatment era Journal of infectious diseases 2015;212 (2):264-274 [PubMed]
Bezemer Daniela, Cori Anne, Ratmann Oliver, van Sighem Ard, Hermanides Hillegonda S., Dutilh Bas E., Gras Luuk, Rodrigues Faria Nuno, van den Hengel Rob, Duits Ashley J., Reiss Peter, de Wolf Frank, Fraser Christophe, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Westerman A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., de Looff L. Hage, Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E. Dispersion of the HIV-1 Epidemic in Men Who Have Sex with Men in the Netherlands: A Combined Mathematical Model and Phylogenetic Analysis PLoS medicine 2015;12 (11):e1001898; discussion e1001898 [PubMed]
Tauran Patricia M., Sennang Nurhayana, Rusli Benny, Wiersinga W. Joost, Dance David, Arif Mansyur, Limmathurotsakul Direk Emergence of Melioidosis in Indonesia American journal of tropical medicine and hygiene 2015;93 (6):1160-1163 [PubMed]
Birnie Emma, Wiersinga Willem J., Limmathurotsakul Direk, Grobusch Martin P. Erratum: Melioidosis in Africa: Should we be looking more closely? (Future Microbiology (2015) 10:2 (273-281)) Future microbiology 2015;10 (6):1101
de Jong Hanna K., Achouiti Ahmed, Koh Gavin C. K. W., Parry Christopher M., Baker Stephen, Faiz Mohammed Abul, van Dissel Jaap T., Vollaard Albert M., van Leeuwen Ester M. M., Roelofs Joris J. T. H., de Vos Alex F., Roth Johannes, van der Poll Tom, Vogl Thomas, Wiersinga Willem Joost Expression and function of S100A8/A9 (calprotectin) in human typhoid fever and the murine Salmonella model PLoS neglected tropical diseases 2015;9 (4):e0003663 [PubMed]
de Jong Hanna Katrien Host-pathogen interactions in typhoid fever 2015. 269p. ISBN 9789462951419. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: Parry C. M., Wiersinga W. J.)
Rokx Casper, Fibriani Azzania, van de Vijver David A. M. C., Verbon Annelies, Schutten Martin, Gras Luuk, Rijnders Bart J. A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Lowe S., Oude Lashof A., Posthouwer D., Pronk J. H., Ammerlaan H. S. M., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., Verbon A., Rijnders B. J. A., van Gorp E. C. M., van der Feltz M., Driessen G. J. A., van Rossum A. M. C., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Bouwhuis J. W., Soetekouw R., ten Kate R. W., Kroon F. P., van Dissel J. T. Increased Virological Failure in Naive HIV-1-Infected Patients Taking Lamivudine Compared With Emtricitabine in Combination With Tenofovir and Efavirenz or Nevirapine in the Dutch Nationwide ATHENA Cohort Clinical infectious diseases 2015;60 (1):143-153 [PubMed]
Birnie Emma, Wiersinga Willem J., Limmathurotsakul Direk, Grobusch Martin P. Melioidosis in Africa: should we be looking more closely? Future microbiology 2015;10 (2):273-281 [PubMed]
Zhang S., van sighem A., Kesselring A., Gras L., Prins J. M., Hassink E., Kauffmann R., Richter C., de Wolf F., Reiss P., Bezemer D. O., Gras L. A. J., Kesselring A. M., van Sighem A. I., Smit C., Zaheri S., van Twillert G., Kortmann W., Cohen Stuart J. W. T., Diederen B. M. W., Branger J., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Brinkman K., Blok W. L., Frissen P. H. J., Schouten W. E. M., van den Berk G. E. L., Veenstra J., Lettinga K. D., Mulder J. W., Vrouenraets S. M. E., Lauw F. N., van Goyen Jan, van Eeden A. Risk of non-AIDS-defining events among HIV-infected patients not yet on antiretroviral therapy HIV medicine 2015;16 (5):265-272 [PubMed]
Wessel H., Wiersinga W. J., Biemond B. J., Goorhuis A., Baars P. A., Krediet C. T. P. The best fit: do not discard AL amyloidosis too easily Acta clinica Belgica 2015;70 (1):73-75 [PubMed]
Maude Rapeephan R., de Jong Hanna K., Wijedoru Lalith, Fukushima Masako, Ghose Aniruddha, Samad Rasheda, Hossain Mohammed Amir, Karim Mohammed Rezaul, Faiz Mohammed Abul, Parry Christopher M., Sayeed Abdullah Abu, Hasan Uddin, Pan-Ngum Wirichada, van der Vaart Thomas W., Dutta Asok Kumar, Mahmud Nasir Uddin, Hero Murad, Iqbal Nafiz, Chaudhury Zabeen, Nga Tran Vu Thieu, Duy Pham Thanh, Phat Voong Vinh, Maude Richard J., Baker Stephen, Wiersinga W. Joost, van der Poll Tom, Day Nicholas P., Dondorp Arjen M. The diagnostic accuracy of three rapid diagnostic tests for typhoid fever at Chittagong Medical College Hospital, Chittagong, Bangladesh Tropical medicine & international health 2015;20 (10):1376-1384 [PubMed]
Lankelma J. M., Nieuwdorp M., de Vos W. M., Wiersinga W. J. The gut microbiota in internal medicine: implications for health and disease Netherlands journal of medicine 2015;73 (2):61-68 [PubMed]
Van Mens Thijs E., Wiersinga Willem Joost Therapieduur bij tweede veneuze trombo-embolie Nederlands tijdschrift voor geneeskunde 2015;159 (1)

2014

Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., de Boer Onno J., Weiler Hartmut, van 't Veer Cornelis, van der Poll Tom A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis) PLoS neglected tropical diseases 2014;8 (4):e2819 [PubMed]
Kager Liesbeth M. Coagulation and fibrinolysis in tuberculosis, melioidosis and beyond 2014. 329p. ISBN 9789462034792. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., Wiersinga W. J.)
Cranendonk Duncan R., Opmeer Brent C., Prins Jan M., Wiersinga W. Joost Comparing short to standard duration of antibiotic therapy for patients hospitalized with cellulitis (DANCE): study protocol for a randomized controlled trial BMC infectious diseases 2014;14 (1):235 [PubMed]
Schouten Judith, Wit Ferdinand W., Stolte Ineke G., Kootstra Neeltje A., van der Valk Marc, Geerlings Suzanne E., Prins Maria, Reiss Peter, Kooij K. W., van Zoest R. A., Elsenga B. C., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Gras L. A. J., van Leeuwen E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study Clinical infectious diseases 2014;59 (12):1787-1797 [PubMed]
Lankelma Jacqueline M., Nieuwdorp Max, de Vos Willem M., Wiersinga W. Joost De darmmicrobiota in gezondheid en ziekte Nederlands tijdschrift voor geneeskunde 2014;157:A5901 [PubMed]
Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., van 't Veer Cornelis, van der Poll Tom Deficiency of protease-activated receptor-1 limits bacterial dissemination during severe Gram-negative sepsis (melioidosis) Microbes and infection / Institut Pasteur 2014;16 (2):171-174 [PubMed]
Kamara David A., Ryom Lene, Ross Michael, Kirk Ole, Reiss Peter, Morlat Philippe, Moranne Olivier, Fux Christoph A., Mocroft Amanda, Sabin Caroline, Lundgren Jens D., Smith Colette J., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Ryom L., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Mansfeld M., Nielsen J., Raben D., Lundgren J. D., Brandt R. Salbøl, Rickenbach M., Fanti I., Krum E., Hillebregt M., Geffard S., Sundström A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study BMC nephrology 2014;15 (1):51 [PubMed]
Wiersinga Willem Joost, Leopold Stije J., Cranendonk Duncan R., van der Poll Tom Host innate immune responses to sepsis Virulence 2014;5 (1):36-44 [PubMed]
Petoumenos K., Reiss P., Ryom L., Rickenbach M., Sabin C. A., El-Sadr W., d'Arminio Monforte A., Phillips A. N., de Wit S., Kirk O., Dabis F., Pradier C., Lundgren J. D., Law M. G., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Mansfeld M., Nielsen J., Raben D., Brandt R. Salbøl, Fanti I., Krum E., Hillebregt M., Geffard S., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Increased risk of cardiovascular disease (CVD) with age in HIV-positive men: a comparison of the D:A:D CVD risk equation and general population CVD risk equations HIV medicine 2014;15 (10):595-603 [PubMed]
de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., van Dissel Jaap T., van der Poll Tom, Wiersinga W. Joost Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection BMC immunology 2014;15 (1):30 [PubMed]
Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., Stroo Ingrid, Achouiti Ahmed, van 't Veer Cornelis, Conway Edward M., van der Poll Tom Mice Lacking the Lectin-Like Domain of Thrombomodulin Are Protected Against Melioidosis Critical care medicine 2014;42 (3):E221-E230 [PubMed]
de Jong Hanna K., Koh Gavin C. K. W., Achouiti Ahmed, van der Meer Anne J., Bulder Ingrid, Stephan Femke, Roelofs Joris J. T. H., Day Nick P. J., Peacock Sharon J., Zeerleder Sacha, Wiersinga W. Joost Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis) Intensive Care Medicine Experimental 2014;2 (1):21 [PubMed]
Lodi Sara, Del Amo Julia, Moreno Santiago, Bucher Heiner C., Furrer Hansjakob, Logan Roger, Sterne Jonathan, Pérez-Hoyos Santiago, Jarrín Inma, Phillips Andrew, Olson Ashley, Van Sighem Ard, Reiss Peter, Sabin Caroline, Jose Sophie, Justice Amy, Goulet Joseph, Miró José M., Ferrer Elena, Meyer Laurence, Seng Rémonie, Vourli Georgia, Antoniadou Anastasia, Dabis Francois, Vandenhede Mari Anne, Costagliola Dominique, Abgrall Sophie, Hernán Miguel A., Hernan Miguel, Bansi L., Hill T., Sabin C., Dunn D., Porter K., Glabay A., Gras L. A.J., Kuijpers T. W., Scherpbier H. J., Van Der Meer J. T.M., Wit F. W.M.N., Van Der Poll T., Nellen F. J.B., Geerlings S. E., Van Vugt M., Pajkrt D., Bos J. C., Van Der Valk M., Grijsen M. L., Wiersinga W. J., Lauw F. N. Opportunistic infections and AIDS malignancies early after initiating combination antiretroviral therapy in high-income countries AIDS (London, England) 2014;28 (16):2461-2473 [PubMed]
Kager Liesbeth Martine, van der Poll Tom, Wiersinga Willem Joost The coagulation system in melioidosis: from pathogenesis to new treatment strategies Expert review of anti-infective therapy 2014;12 (8):993-1002 [PubMed]

2013

Smit Mikaela, Smit Colette, Geerlings Suzanne, Gras Luuk, Brinkman Kees, Hallett Timothy B., de Wolf Frank, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Lowe S., Schreij G., Oude Lashof A., Posthouwer D., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., tot Pannerden M. H. Nispen, Verbon A., Rijnders B. J. A., van Gorp E. C. M., Hassing R. J., Smeulders A. W. M., Hartwig N. G., Driessen G. J. A., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., Soetekouw R., ten Kate R. W. Changes in first-line cART regimens and short-term clinical outcome between 1996 and 2010 in The Netherlands PLoS ONE 2013;8 (9):e76071 [PubMed]
Kager L. M., Wiersinga W. J., Roelofs J. J., Meijers J. C. M., Zeerleder S. S., Esmon C. T., van't Veer C., van der Poll T. Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis) Journal of thrombosis and haemostasis 2013;11 (2):282-292 [PubMed]
Kager Liesbeth M., Weehuizen Tassili A., Wiersinga W. Joost, Roelofs Joris J. T. H., Meijers Joost C. M., Dondorp Arjen M., van 't Veer Cornelis, van der Poll Tom Endogenous α2-antiplasmin is protective during severe gram-negative sepsis (melioidosis) American journal of respiratory and critical care medicine 2013;188 (8):967-975 [PubMed]
Koh Gavin C. K. W., Weehuizen Tassili A., Breitbach Katrin, Krause Kathrin, de Jong Hanna K., Kager Liesbeth M., Hoogendijk Arjan J., Bast Antje, Peacock Sharon J., van der Poll Tom, Steinmetz Ivo, Wiersinga W. Joost Glyburide reduces bacterial dissemination in a mouse model of melioidosis PLoS neglected tropical diseases 2013;7 (10):e2500 [PubMed]
Wiersinga W. J., Schimmer B., Levi M. [=Marcel M.] Handboek voor de coassistent (4e dr.)Houten: Bohn Stafleu; 2013. ISBN 9789031398027
Schoffelen Annelot F., van Lelyveld Steven F. L., Barth Roos E., Gras Luuk, de Wolf Frank, Netea Mihai G., Hoepelman Andy I. M., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Lowe S., Schreij G., Oude Lashof A., Posthouwer D., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., Nispen tot Pannerden M. H., Verbon A., Rijnders B. J. A., van Gorp E. C. M., Hassing R. J., Smeulders A. W. M., Hartwig N. G., Driessen G. J. A., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., Soetekouw R. Lower incidence of Pneumocystis jirovecii pneumonia among Africans in the Netherlands host or environmental factors? AIDS (London, England) 2013;27 (7):1179-1184 [PubMed]
Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., de Boer Onno J., Meijers Joost C. M., Isermann Berend, van't Veer Cornelis, van der Poll Tom Overexpression of activated protein C is detrimental during severe experimental gram-negative sepsis (melioidosis) Critical care medicine 2013;41 (10):e266-e274 [PubMed]
Kager Liesbeth M., Schouten Marcel, Wiersinga W. Joost, de Boer J. Daan, Lattenist Lionel C. W., Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, Dondorp Arjen M., Esmon Charles T., van 't Veer Cornelis, van der Poll Tom Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis) PLoS neglected tropical diseases 2013;7 (7):e2306 [PubMed]
Schuijt Tim J., van der Poll Tom, de Vos Willem M., Wiersinga W. Joost The intestinal microbiota and host immune interactions in the critically ill Trends in microbiology 2013;21 (5):221-229 [PubMed]

2012

Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, van't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator impairs host defense during severe experimental gram-negative sepsis (melioidosis) Critical care medicine 2012;40 (7):2168-2175 [PubMed]
Weehuizen Tassili A. F., Wieland Catharina W., van der Windt Gerritje J. W., Duitman Jan-Willem, Boon Louis, Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga W. Joost Expression and Function of Transforming Growth Factor beta in Melioidosis Infection and immunity 2012;80 (5):1853-1857 [PubMed]
de Jong Hanna K., Parry Chris M., van der Poll Tom, Wiersinga W. Joost Host-Pathogen Interaction in Invasive Salmonellosis PLoS pathogens 2012;8 (10):e1002933 [PubMed]
Wiersinga Willem J., van der Poll Tom Infectie en onstekingin: A. B. J. Groeneveld, M. J. Schultz, M. B. Vroom, editors. Handboek multiorgaanfalen. Utrecht: De Tijdstroom; 2012., ISBN 9789058981912
Koh Gavin C. K. W., Vlaar Alexander P. J., Hofstra Jorrit J., de Jong H. Katrien, van Nierop Samuel, Peacock Sharon J., Wiersinga W. Joost, Schultz Marcus J., Juffermans Nicole P. In the critically ill patient, diabetes predicts mortality independent of statin therapy but is not associated with acute lung injury: A cohort study Critical care medicine 2012;40 (6):1835-1843 [PubMed]
van Lelyveld Steven F. L., Gras Luuk, Kesselring Anouk, Zhang Shuangjie, de Wolf Frank, Wensing Annemarie M. J., Hoepelman Andy I. M., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Schreij G., Lowe S., Oude Lashof A., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., van der Feltz M., Nouwen J. L., Gelinck L. B. S., Verbon A., Rijnders B. J. A., Slobbe L., van Gorp E. C. M., Hartwig N. G., Driessen G. J. A., Branger J., Schippers E. F., van Nieuwkoop C., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., ten Kate R. W., Soetekouw R. Long-term complications in patients with poor immunological recovery despite virological successful HAART in Dutch ATHENA cohort AIDS (London, England) 2012;26 (4):465-474 [PubMed]
Wiersinga W. Joost, Currie Bart J., Peacock Sharon J. Melioidosis New England journal of medicine 2012;367 (11):1035-1044 [PubMed]
Wiersinga W. J., Bonten M. J., Boersma W. G., Jonkers R. E., Aleva R. M., Kullberg B. J., Schouten J. A., Degener J. E., Janknegt R., Verheij T. J., Sachs A. P. E., Prins J. M. SWAB/NVALT (Dutch Working Party on Antibiotic Policy and Dutch Association of Chest Physicians) Guidelines on the Management of Community-Acquired Pneumonia in Adults Netherlands journal of medicine 2012;70 (2):90-101 [PubMed]
Koh G. C. K. W., Peacock S. J., van der Poll T., Wiersinga W. J. The impact of diabetes on the pathogenesis of sepsis European journal of clinical microbiology & infectious diseases 2012;31 (4):379-388 [PubMed]
Wiersinga Willem Joost, Prins Jan M., van de Beek Diederik Therapy-Resistant Opsoclonus-Myoclonus Syndrome Secondary to HIV-1 Infection Clinical infectious diseases 2012;54 (3):447-448 [PubMed]
Lipsitz Rebecca, Garges Susan, Aurigemma Rosemarie, Baccam Prasith, Blaney David D., Cheng Allen C., Currie Bart J., Dance David, Gee Jay E., Larsen Joseph, Limmathurotsakul Direk, Morrow Meredith G., Norton Robert, O'Mara Elizabeth, Peacock Sharon J., Pesik Nicki, Rogers L. Paige, Schweizer Herbert P., Steinmetz Ivo, Tan Gladys, Tan Patrick, Wiersinga W. Joost, Wuthiekanun Vanaporn, Smith Theresa L. Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 Emerging infectious diseases 2012;18 (12):e2 [PubMed]

2011

Wiersinga W. Joost Current insights in sepsis: from pathogenesis to new treatment targets Current opinion in critical care 2011;17 (5):480-486 [PubMed]
Koh Gavin C. K. W., Meijers Joost C. M., Maude Rapeephan R., Limmathurotsakul Direk, Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga Willem J. Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis) Thrombosis and haemostasis 2011;106 (6):1139-1148 [PubMed]
Koh Gavin C. K. W., Maude Rapeephan R., Schreiber M. Fernanda, Limmathurotsakul Direk, Wiersinga W. Joost, Wuthiekanun Vanaporn, Lee Sue J., Mahavanakul Weera, Chaowagul Wipada, Chierakul Wirongrong, White Nicholas J., van der Poll Tom, Day Nicholas P. J., Dougan Gordon, Peacock Sharon J. Glyburide Is Anti-inflammatory and Associated with Reduced Mortality in Melioidosis Clinical infectious diseases 2011;52 (6):717-725 [PubMed]
Kager L. M., Wiersinga W. J., Roelofs J. J. T. H., Meijers J. C. M., Levi M. [=Marcel M.], van't Veer C., van der Poll T. Plasminogen activator inhibitor type I contributes to protective immunity during experimental Gram-negative sepsis (melioidosis) Journal of thrombosis and haemostasis 2011;9 (10):2020-2028 [PubMed]
van der Poll Tom, van Zoelen Marieke A. D., Wiersinga W. Joost Regulation of pro- and anti-inflammatory host responses Contributions to microbiology 2011;17:125-136 [PubMed]

2010

Wiersinga W. Joost Beyond Antibiotics: New Horizons in Treating Burkholderia Species Infections Journal of infectious diseases 2010;201 (12):1786-1787 [PubMed]
van Munster Barbara C., Bisschop Peter H., Zwinderman Aeilko H., Korevaar Johanna C., Endert Erik, Wiersinga W. Joost, van Oosten Hannah E., Goslings J. Carel, de Rooij Sophia E. J. A. Cortisol, interleukins and S100B in delirium in the elderly Brain and cognition 2010;74 (1):18-23 [PubMed]
Wiersinga W. Joost, Calandra Thierry, Kager Liesbeth M., van der Windt Gerritje J. W., Roger Thierry, le Roy Didier, Florquin Sandrine, Peacock Sharon J., Sweep Fred C. G. J., van der Poll Tom Expression and Function of Macrophage Migration Inhibitory Factor (MIF) in Melioidosis PLoS neglected tropical diseases 2010;4 (2):e605 [PubMed]
Hoogerwerf Jacobien J., van Zoelen Marieke A., Wiersinga W. Joost, van 't Veer Cornelis, de Vos Alex F., de Boer Anita, Schultz Marcus J., Hooibrink Berend, de Jonge Evert, van der Poll Tom Gene Expression Profiling of Apoptosis Regulators in Patients with Sepsis Journal of innate immunity 2010;2 (5):461-468 [PubMed]
van der Windt Gerritje J. W., Wiersinga W. Joost, Wieland Catharina W., Tjia Ivo C. S. I., Day Nicholas P., Peacock Sharon J., Florquin Sandrine, van der Poll Tom Osteopontin Impairs Host Defense during Established Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis) PLoS neglected tropical diseases 2010;4 (8):e806 [PubMed]
Anas A. A., Wiersinga W. J., de Vos A. F., van der Poll T. Recent insights into the pathogenesis of bacterial sepsis Netherlands journal of medicine 2010;68 (4):147-152 [PubMed]
Wiersinga W. Joost, Van Der Poll Tom Sepsis: Nieuwe inzichten in de pathogenese en behandeling Nederlands tijdschrift voor geneeskunde 2010;154 (6):268-275
Wiersinga W. J., van der Poll T. Sepsis: nieuwe inzichten in de pathogenese en behandeling Nederlands tijdschrift voor geneeskunde 2010;154 (6):A1130 [PubMed]
de Jong Hanna Katrien, van der Poll Tom, Wiersinga Willem Joost The Systemic Pro-Inflammatory Response in Sepsis Journal of innate immunity 2010;2 (5):422-430 [PubMed]
Wiersinga W. Joost, Kager Liesbeth M., Hovius Joppe W. R., van der Windt Gerritje J. W., de Vos Alex F., Meijers Joost C. M., Roelofs Joris J., Dondorp Arjen, Levi Marcel, Day Nicholas P., Peacock Sharon J., van der Poll Tom Urokinase Receptor Is Necessary for Bacterial Defense against Pneumonia-Derived Septic Melioidosis by Facilitating Phagocytosis Journal of immunology (Baltimore, Md. 2010;184 (6):3079-3086 [PubMed]

2009

Wiersinga W. Joost, van der Poll Tom Burkholderia pseudomallei Tropism and the Melioidosis Road Map Journal of infectious diseases 2009;199 (12):1720-1722 [PubMed]
Wiersinga W. J., de Haes J. C. J. M. Communicatievaardighedenin: W. J. Wiersinga, B. Schimmer, M. [=Marcel M.] Levi, editors. Handboek voor de coassistent. Houten: Bohn Stafleu Van Loghum; 2009. p. 33-40, ISBN 9789031355655
Wiersinga W. J., Schimmer B., Levi M. [=Marcel M.] Handboek voor de coassistent (3e herz. dr.)Houten: Bohn Stafleu Van Loghum; 2009. ISBN 9789031355655
Wiersinga Willem J., van der Poll Tom Immunity to Burkholderia pseudomallei Current opinion in infectious diseases 2009;22 (2):102-108 [PubMed]
Wiersinga Willem Joost, van't Veer Cornelis, van den Pangaart Petra S., Dondorp Arjen M., Day Nicholas P., Peacock Sharon J., van der Poll Tom Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis) Critical care medicine 2009;37 (2):569-576 [PubMed]
van der Windt Gerritje J. W., Wieland Catharina W., Wiersinga Willem J., Florquin Sandrine, van der Poll Tom Osteopontin is not crucial to protective immunity during murine tuberculosis Immunology 2009;128 (1 Suppl):e766-e776 [PubMed]
Hovius Joppe W. R., Bijlsma Maarten F., van der Windt Gerritje J. W., Wiersinga W. Joost, Boukens Bastiaan J. D., Coumou Jeroen, Oei Anneke, de Beer Regina, de Vos Alex F., van 't Veer Cornelis, van Dam Alje P., Wang Penghua, Fikrig Erol, Levi Marcel M., Roelofs Joris J. T. H., van der Poll Tom The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi PLoS pathogens 2009;5 (5):e1000447 [PubMed]
Wiersinga W. J., Limmathurotsakul D., Cheng A. C. Turning green with shock Netherlands journal of medicine 2009;67 (7):291-+ [PubMed]

2008

Wiersinga W. J., Meijers J. C. M., Levi M. [=Marcel M.], van 't Veer C., Day N. P., Peacock S. J., van der Poll T. Activation of coagulation with concurrent impairment of anticoagulant mechanisms correlates with a poor outcome in severe melioidosis Journal of thrombosis and haemostasis 2008;6 (1):32-39 [PubMed]
Wieland Catharina W., van der Windt Gerritje J. W., Wiersinga W. Joost, Florquin Sandrine, van der Poll Tom CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis Immunology 2008;125 (2):272-279 [PubMed]
Wiersinga W. Joost, de Vos Alex F., Wieland Catharina W., Leendertse Masja, Roelofs Joris J. T. H., van der Poll Tom CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice Journal of infectious diseases 2008;198 (9):1388-1397 [PubMed]
Wiersinga W. Joost, Dessing Mark C., van der Poll Tom Gene-expression profiles in murine melioidosis Microbes and infection / Institut Pasteur 2008;10 (8):868-877 [PubMed]
Schouten Marcel, Wiersinga Willem Joost, Levi Marcel, van der Poll Tom Inflammation, endothelium, and coagulation in sepsis Journal of leukocyte biology 2008;83 (3):536-545 [PubMed]
Wiersinga W. Joost, de Vos Alex F., de Beer Regina, Wieland Catharina W., Roelofs Joris J. T. H., Woods Donald E., van der Poll Tom Inflammation patterns induced by different Burkholderia species in mice Cellular microbiology 2008;10 (1):81-87 [PubMed]
Wiersinga W. Joost, Wieland Catharina W., Roelofs Joris J. T. H., van der Poll Tom MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei PLoS ONE 2008;3 (10):e3494 [PubMed]
Wiersinga W. J. On Toll-like receptors and the innate immune response in sepsis caused by Burkholderia pseudomallei (melioidosis) 2008. 295p. ISBN 9789064642890. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Peacock S. J.)
van Munster Barbara C., Korevaar Johanna C., Zwinderman Aeilko H., Levi Marcel, Wiersinga W. Joost, de Rooij Sophia E. Time-course of cytokines during delirium in elderly patients with hip fractures Journal of the American Geriatrics Society 2008;56 (9):1704-1709 [PubMed]
Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., van den Pangaart Petra S., Wiersinga W. Joost, de Vos Alex F., Florquin Sandrine, Bonten Marc J. M., van der Poll Tom TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis Journal of immunology (Baltimore, Md. 2008;180 (7):4865-4874 [PubMed]

2007

Wiersinga W. J., Levi M. [=Marcel M.], van der Poll T. Coagulation in Sepsisin: E. Abraham, M. Singer, editors. Mechanisms of sepsis induced organ dysfunction and recovery. S.l.: Springer; 2007. p. 273-285, ISBN 9783540301585; 9783540301578
Wiersinga W. Joost, Wieland Catharina W., van der Windt Gerritje J. W., de Boer Anita, Florquin Sandrine, Dondorp Arjen, Day Nicholas P., Peacock Sharon J., van der Poll Tom Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis Infection and immunity 2007;75 (8):3739-3746 [PubMed]
Wiersinga W. Joost, Veer Cees van T., Wieland Catharina W., Gibot Sebastien, Hooibrink Berend, Day Nicholas P., Peacock Sharon J., van der Poll Tom Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis Journal of infectious diseases 2007;196 (11):1707-1716 [PubMed]
Wiersinga W. Joost, Dessing Mark C., Kager Piet A., Cheng Allen C., Limmathurotsakul Direk, Day Nicholas P., Dondorp Arjen M., van der Poll Tom, Peacock Sharon J. High-throughput mRNA profiling characterizes the expression of inflammatory molecules in sepsis caused by Burkholderia pseudomallei Infection and immunity 2007;75 (6):3074-3079 [PubMed]
Wiersinga Willem Joost, van der Poll Tom Is the septic response good or bad? Current infectious disease reports 2007;9 (5):366-373 [PubMed]
Hommes T. J., Wiersinga W. J., Van Der Poll T. The host response to sepsisin: Yearbook of Intensive Care and Emergency Medicine 2009. Springer New York; 2007. p. 39-50, ISBN 9780387922775
Wiersinga W. Joost, Wieland Catharina W., Dessing Mark C., Chantratita Narisara, Cheng Allen C., Limmathurotsakul Direk, Chierakul Wirongrong, Leendertse Masja, Florquin Sandrine, de Vos Alex F., White Nicholas, Dondorp Arjen M., Day Nicholas P., Peacock Sharon J., van der Poll Tom Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis) PLoS medicine 2007;4 (7):1268-1280 [PubMed]
Wiersinga W. J., van der Poll T. Toll-like receptors and sepsisin: M. J. Schultz, P. E. Spronk, editors. Immunology in Intensive Care Medicine. S.l.: Research Signpost; 2007. p. 75-89, ISBN 9788130800448

2006

Wiersinga W. J., De Rooij S. E.J.A., Huijmans J. G.M., Fischer J. C., Hoekstra J. B.L. De diagnostiek van vitamine B₁₂-deficiëntie herzien Nederlands tijdschrift voor geneeskunde 2006;150 (8):461
Wiersinga Willem Joost, Scheepstra Cornelis G., Kasanardjo Jocelyn S., de Vries Peter J., Zaaijer Hans, Geerlings Suzanne E. Dengue fever-induced hemolytic uremic syndrome Clinical infectious diseases 2006;43 (6):800-801 [PubMed]
Bousema J. T., Schimmer B., Wiersinga W. J., Boeree M. J., Borgdorff M. W., Sauerwein R. W. Leidraad intenational health voor een coschap of stage in ontwikkelingslandenHouten: Bohn Stafleu Van Loghum; 2006. ISBN 9789031341825
Wiersinga W. Joost, van der Poll Tom, White Nicholas J., Day Nicholas P., Peacock Sharon J. Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei Nature reviews. Microbiology 2006;4 (4):272-282 [PubMed]
Wiersinga W. J., van der Poll T. The role of Toll-like receptors in sepsisin: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2006. S.l.: Springer-Verlag; 2006. p. 3-13

2005

Wiersinga W. J., de Rooij S. E. J. A., Huijmans J. G. M., Fischer C., Hoekstra J. B. L. De diagnostiek van vitamine-B12-deficiëntie herzien Nederlands tijdschrift voor geneeskunde 2005;149 (50):2789-2794 [PubMed]
Wiersinga W. J., van der Poll T. 'Toll-like' receptoren en de betekenis voor de kliniek Nederlands tijdschrift voor geneeskunde 2005;149 (21):1150-1155 [PubMed]

2004

Wiersinga W. J., de Haes J. C. J. M. Communicatievaardighedenin: W. J. Wiersinga, B. Schimmer, M. [=Marcel M.] Levi, editors. Handboek voor de coassistent. Houten / Antwerpen: Bohn Stafleu Van Loghum; 2004. p. 28-ev., ISBN 9789031342594
Wiersinga W. J., Schimmer B., Levi M. [=Marcel M.] Handboek voor de coassistent (2e druk)Houten / Antwerpen: Bohn Stafleu Van Loghum; 2004. ISBN 9789031342594
Wiersinga W. J., van Dellen Q. M., Spanjaard L., van Kan H. J. M., Groen A. L., Wetsteyn J. C. F. M. High mortality among patients with bacterial meningitis in a rural hospital in Tanzania Annals of tropical medicine and parasitology 2004;98 (3):271-278 [PubMed]
Wiersinga W. J., de Jonge M. C., Bergman J. J., Busch O. R., Schipper H. G. Reuzendivertikel van het sigmoïd Nederlands tijdschrift voor geneeskunde 2004;148 (3):143-147 [PubMed]

2003

Wiersinga W. J., Jansen M. C., Straatsburg I. H., Davids P. H., Klaase J. M., Gouma D. J., van Gulik T. M. Lesion progression with time and the effect of vascular occlusion following radiofrequency ablation of the liver British journal of surgery 2003;90 (3):306-312 [PubMed]

2002

Wiersinga W. J., de Haes J. C. J. M. Communicatietechnieken. Waarom zijn communicatietechnieken nodig?in: W. J. Wiersinga, B. Schimmer, M. [=Marcel M.] Levi, editors. Handboek voor de coassistent. Houten: Bohn Stafleu Van Loghum; 2002. p. 28-34
Wiersinga W. J., Schimmer B., Levi M. [=Marcel M.] Handboek voor de coassistentHouten: Bohn Stafleu Van Loghum; 2002.

2001

Wiersinga W. J., de Reijke T. M., Blank L. E. Local tract metastasis of prostatic adenocarcinoma 8 years after (125)iodine brachytherapy Journal of urology 2001;166 (3):995 [PubMed]

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