Prof. T. van der Poll PhD publications

foto

Publications Prof. PhD T. van der Poll

Position
Full Professor
Main activities
Patient care, Research, Other
Specialisation
Internal Medicine & Infectious Diseases
Focus of research

The research headed by Van der Poll has a strong translational character with sepsis (and its major cause pneumonia) as the main topic. Focus lies on the innate immune response, in particular pattern recognition receptors, and on the regulation of the procoagulant response. The Key objective is to determine the mechanisms by which the innate immune and procoagulant responses to infection are initiated and subsequently regulated. This research makes use of both observational studies in patients with clinical disease (in particular sepsis and pneumonia) and mechanistic investigations in healthy volunteers (who are exposed to bacterial products via the intravenous or intrabronchial route) and genetically modified mice lacking or over-expressing proteins implicated in innate immunity or coagulation (in which clinically relevant models of sepsis have been established).

Contained within this research, Van der Poll is the leading scientist in biomarker discovery and validation in 3 large European projects on pneumonia, peritonitis and sepsis (COMBACTE-CARE, COMBACTE-MAGNET and SEPCELL), which provides unique opportunities to further expand the translational research by his group

Amsterdam UMC Research Institutes
AMC departments
All publications

2021

  • Otto Natasja A., Butler Joe M., Ramirez-Moral Ivan, van Weeghel Michel, van Heijst Jeroen W. J., Scicluna Brendon P., Houtkooper Riekelt H., de Vos Alex F., van der Poll Tom Adherence affects monocyte innate immune function and metabolic reprogramming after lipopolysaccharide stimulation in vitro Journal of immunology (Baltimore, Md. 2021;206 (4):827-838 [PubMed]
  • Netea Mihai G., Balkwill Frances, Chonchol Michel, Cominelli Fabio, Donath Marc Y., Giamarellos-Bourboulis Evangelos J., Golenbock Douglas, Gresnigt Mark S., Heneka Michael T., Hoffman Hal M., Hotchkiss Richard, Joosten Leo A. B., Kastner Daniel L., Korte Martin, Latz Eicke, Libby Peter, Mandrup-Poulsen Thomas, Mantovani Alberto, Mills Kingston H. G., Nowak Kristen L., O’Neill Luke A., Pickkers Peter, van der Poll Tom, Ridker Paul M., Schalkwijk Joost, Schwartz David A., Siegmund Britta, Steer Clifford J., Tilg Herbert, van der Meer Jos W. M., van de Veerdonk Frank L., Dinarello Charles A. Author Correction: A guiding map for inflammation (Nature Immunology, (2017), 18, 8, (826-831), 10.1038/ni.3790) Nature immunology 2021;22 (2):254 [PubMed]
  • Qin Wanhai, Brands Xanthe, van't Veer Cornelis, de Vos Alex F., Scicluna Brendon P., van der Poll Tom Bronchial Epithelial Tet2 Maintains Epithelial Integrity during Acute Pseudomonas aeruginosa Pneumonia Infection and immunity 2021;89 (1) [PubMed]
  • Smit Colette, Boyd Anders, Rijnders Bart J. A., van de Laar Thijs J. W., Leyten Eliane M., Bierman Wouter F., Newsum Astrid M., Schinkel Janke, Prins Maria, van der Valk Marc, Reiss Peter, van der Valk M., Geerlings S. E., Goorhuis A., Hovius J. W., Nellen F. J. B., van der Poll T., Prins J. M., van Vugt M., Wiersinga W. J., Wit F. W. M. N., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Wolthers K. C., Sigaloff K. C. E., Ang C. W., Reuwer A., Nellen J., van Nood E., Renckens R., Kok M., Hoogerwerf J., Richel O., Stelma F. F., Langebeek N., Lauw F. N., van Wijk M., Bakker M., Stienstra Y., Reiss P., Bezemer D. O., van Sighem A. I., Smit C., van de Sande L., Groters M., Schoorl M. HCV micro-elimination in individuals with HIV in the Netherlands 4 years after universal access to direct-acting antivirals: a retrospective cohort study Lancet HIV 2021;8 (2):e96-e105 [PubMed]
  • Ramirez-Moral I., Yu X., Butler J. M., van Weeghel M., Otto N. A., Ferreira B. Lima, Maele L. Van, Sirard J. C., de Vos A. F., de Jong M. D., Houtkooper R. H., van der Poll T. mTOR-driven glycolysis governs induction of innate immune responses by bronchial epithelial cells exposed to the bacterial component flagellin Mucosal immunology 2021 [PubMed]

2020

  • van Mourik Niels, Geerts Bart F, Binnekade Jan M, Veelo Denise P, Bos Lieuwe D J, Wiersinga W Joost, van der Poll Tom, Cremer Olaf L, Schultz Marcus J, Vlaar Alexander P J A Higher Fluid Balance in the Days After Septic Shock Reversal Is Associated With Increased Mortality: An Observational Cohort Study Critical Care Explorations 2020;2 (10):e0219 [PubMed]
  • Juschten Jenny, Ingelse Sarah A, Bos Lieuwe D J, Girbes Armand R J, Juffermans Nicole P, van der Poll Tom, Schultz Marcus J, Tuinman Pieter Roel, Study group members AMC , Lagrand Wim K., Horn Johanna Alkaline phosphatase in pulmonary inflammation-a translational study in ventilated critically ill patients and rats Intensive Care Medicine Experimental 2020;8 (Suppl 1):46 [PubMed]
  • Laterre Pierre-François, Sánchez-García Miguel, van der Poll Tom, de la Rosa Olga, Cadogan Kathy-Ann, Lombardo Eleuterio, François Bruno A phase Ib/IIa, randomised, double-blind, multicentre trial to assess the safety and efficacy of expanded Cx611 allogeneic adipose-derived stem cells (eASCs) for the treatment of patients with community-acquired bacterial pneumonia admitted to the intensive care unit BMC pulmonary medicine 2020;20 (1) [PubMed]
  • Yang Jack, van’t Veer Cornelis, ten Brink Marieke S., de Vos Alex F., van der Poll Tom C3a signaling is not involved in eosinophil migration during experimental allergic lung inflammation in mice Allergy 2020;75 (4):934-936 [PubMed]
  • Perlee Desiree, de Beer Regina, Florquin Sandrine, van der Poll Tom, van 't Veer Cornelis, de Vos Alex F. Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation American journal of physiology. Lung cellular and molecular physiology 2020;319 (1):L105-L114 [PubMed]
  • Brands Xanthe, Haak Bastiaan W., Klarenbeek Augustijn M., Otto Natasja A., Faber Daniël R., Lutter René, Scicluna Brendon P., Wiersinga W. Joost, van der Poll Tom Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia Frontiers in immunology 2020;11 [PubMed]
  • Birnie Emma, Koh Gavin C. K. W., Löwenberg Ester C., Meijers Joost C. M., Maude Rapeephan R., Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga W. Joost Correction: Increased von willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis (PLoS Negl Trop Dis 11(3), e0005468, 10.1371/journal.pntd.0005468 PMID: 28296884) PLoS neglected tropical diseases 2020;14 (9) [PubMed]
  • Brands Xanthe, Haak Bastiaan W., Klarenbeek Augustijn M., Otto Natasja A., Faber Daniël R., Lutter René, Scicluna Brendon P., Wiersinga W. Joost, van der Poll Tom Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia (Front. Immunol, (2020), 11, (796), 10.3389/fimmu.2020.00796) Frontiers in immunology 2020;11 [PubMed]
  • Jacobs Max C., Lankelma Jacqueline M., Wolff Nora S., Hugenholtz Floor, de Vos Alex F., van der Poll Tom, Wiersinga W. Joost Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation PLoS ONE 2020;15 (11 November) [PubMed]
  • Yang Jack, van Engelen Tjitske S. R., Haak Bastiaan W., Bonta Peter I., Majoor Christof J., van 't Veer Cornelis, de Vos Alex F., Kemper E. Marleen, Lutter René, van Mierlo Gerard, Zeerleder Sacha S., Bel Elisabeth H., van der Poll Tom Effect of C1-inhibitor in adults with mild asthma: A randomized controlled trial Allergy 2020;75 (4):953-955 [PubMed]
  • Meijer Mariska T., Uhel Fabrice, Cremer Olaf L., Scicluna Brendon P., Schultz Marcus J., van der Poll Tom Elevated trefoil factor 3 plasma levels in critically ill patients with abdominal sepsis or non-infectious abdominal illness Cytokine 2020;133 [PubMed]
  • Klein Klouwenberg Peter M. C., Spitoni Cristian, van der Poll Tom, Bonten Marc J., Cremer Olaf L., Schultz Marcus J., Horn Janneke, Scicluna Brendon, Wiewel Maryse A., Frencken Jos F., Groep Kirsten Van De, Koster-Brouwer Marlies E., Ong David S. Y., Verboom Diana, de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk, Hoogendijk Arie J., Huson Mischa A., van Vught Lonneke A. Erratum: Predicting the clinical trajectory in critically ill patients with sepsis: A cohort study (Critical Care (2019) 2 (408) DOI: 10.1186/s13054-019-2687-z) Critical care (London, England) 2020;24 (1) [PubMed]
  • Hoornenborg Elske, Coyer Liza, Boyd Anders, Achterbergh Roel Christiaan Alfons, Schim van der Loeff Maarten Franciscus, Bruisten Sylvia, de Vries Henry John Christiaan, Koopsen Jelle, van de Laar Thijs J. W., Prins Maria, van Bergen J. E. A. M., de Bree G. J., Brokx P., Deug F., Heidenrijk M., Prins M., Reiss P., van der Valk M., Davidovich U., Geerlings S. E., Hoornenborg E., Oomen A., Sighem A. van, Zuilhof W., Bruinderink M. L. Groot, Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Bezemer D., van Bijnen A., Dijkstra M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., Hankins C. A., Hogewoning A., Hovius J. W., Kootstra N. A., Lauw F., van der Meer J. T., Mulder B. J., Nellen F. J., van der Poll T., van Rooijen M. S., Sonder G. J., de Vries H. J., Wiersinga W. J., Wit F. W. High incidence of HCV in HIV-negative men who have sex with men using pre-exposure prophylaxis Journal of hepatology 2020;72 (5):855-864 [PubMed]
  • Reijnders Tom D. Y., Saris Anno, Schultz Marcus J., van der Poll Tom Immunomodulation by macrolides: therapeutic potential for critical care lancet. Respiratory medicine 2020;8 (6):619-630
  • Ramirez-Moral Ivan, Blok Dana C., Bernink Jochem H., Garcia-Laorden M. Isabel, Florquin Sandrine, Boon Louis, van't Veer Cornelis, Mack Matthias, Saluzzo Simona, Knapp Sylvia, Spits Hergen, de Vos Alex F., van der Poll Tom Interleukin-33 improves local immunity during Gram-negative pneumonia by a combined effect on neutrophils and inflammatory monocytes Journal of pathology 2020 [PubMed]
  • Haak Bastiaan W. Intestinal microbiota and host defense in systemic infectious diseases: Translational studies in the healthy and the ill 2020. 373p. ISBN 9789463759045. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga Willem J., Levi Marcel M.; Co-supervisor: van der Poll Tom)
  • Dickson Robert P., Schultz Marcus J., van der Poll Tom, Schouten Laura R., Falkowski Nicole R., Luth Jenna E., Sjoding Michael W., Brown Christopher A., Chanderraj Rishi, Huffnagle Gary B., Bos Lieuwe D. J., Study group members AMC , Lagrand Wim K., Horn Johanna Lung microbiota predict clinical outcomes in critically ill patients American journal of respiratory and critical care medicine 2020;201 (5):555-563 [PubMed]
  • Otto Natasja A., Butler Joe M., Ramirez-Moral Ivan, Hoogerwerf Jacobien J., Houtkooper Riekelt H., de Vos Alex F., van der Poll Tom Metabolic adaptations of human alveolar macrophages upon activation by lipopolysaccharide in vivo Scandinavian journal of immunology 2020 [PubMed]
  • Uhel Fabrice, Peters-Sengers Hessel, Falahi Fahimeh, Scicluna Brendon P., van Vught Lonneke A., Bonten Marc J., Cremer Olaf L., Schultz Marcus J., van der Poll Tom Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study Intensive care medicine 2020;46 (8):1576-1589 [PubMed]
  • Uhel Fabrice, van der Poll Tom Norepinephrine in Septic Shock: A Mixed Blessing American journal of respiratory and critical care medicine 2020;202 (6):788-789 [PubMed]
  • van der Poll Tom, Parker Robert I. Platelet Activation and Endothelial Cell Dysfunction Critical care clinics 2020;36 (2):233-253 [PubMed]
  • Ding Chao, Scicluna Brendon P., Stroo Ingrid, Yang Jack, Roelofs Joris J. TH, de Boer Onno J., de Vos Alex F., Nürnberg Peter, Revenko Alexey S., Crosby Jeff, van't Veer Cornelis, van der Poll Tom Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice Journal of pathology 2020;250 (1):95-106 [PubMed]
  • Iba Toshiaki, Levy Jerrold H., Warkentin Theodore E., Thachil Jecko, van der Poll Tom, Levi Marcel RE: The prothrombin time ratio is not a more effective marker for evaluating sepsis-induced coagulopathy than fibrin-related markers: Response to the Letter-to-the-Editor by Dr Wada Journal of thrombosis and haemostasis 2020;18 (6):1507-1509 [PubMed]
  • de Vos Alex F., van der Poll Tom SIRP-α instructs alveolar macrophages to stop eating after pneumonia Nature immunology 2020;21 (6):601-603 [PubMed]
  • Meijer Mariska T, Uhel Fabrice, Cremer Olaf L, Schultz Marcus J, van der Poll Tom Tenascin C Plasma Levels in Critically Ill Patients with or Without Sepsis: A Multicenter Observational Study Shock (Augusta, Ga.) 2020;54 (1):62-69 [PubMed]
  • Khan Hina N., Brands Xanthe, Aufiero Simona, Hoogendijk Arie J., Klarenbeek Augustijn M., van Engelen Tjitske S. R., Haak Bastiaan W., van Vught Lonneke A., Horn Janneke, Schultz Marcus J., Zwinderman Aeilko H., van der Poll Tom, Scicluna Brendon P. The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis Critical care (London, England) 2020;24 (1) [PubMed]
  • de Beer Friso M, Wieske Luuk, van Mierlo Gerard, Wouters Diana, Zeerleder Sacha, Bos Lieuwe D, Juffermans Nicole P, Schultz Marcus J, van der Poll Tom, Lagrand Wim K, Horn Janneke The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients Intensive Care Medicine Experimental 2020;8 (Suppl 1):74 [PubMed]
  • Scicluna Brendon P, Uhel Fabrice, van Vught Lonneke A, Wiewel Maryse A, Hoogendijk Arie J, Baessman Ingelore, Franitza Marek, Nürnberg Peter, Horn Janneke, Cremer Olaf L, Bonten Marc J, Schultz Marcus J, van der Poll Tom The leukocyte non-coding RNA landscape in critically ill patients with sepsis eLife 2020;9:1-23 [PubMed]
  • van Meenen David M P, Serpa Neto Ary, Paulus Frederique, Merkies Coen, Schouten Laura R, Bos Lieuwe D, Horn Janneke, Juffermans Nicole P, Cremer Olaf L, van der Poll Tom, Schultz Marcus J The predictive validity for mortality of the driving pressure and the mechanical power of ventilation Intensive Care Medicine Experimental 2020;8 (Suppl 1):60 [PubMed]
  • Yang Junjie The role of the complement and contact systems in asthma 2020. 200p. ISBN 9789493184411. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll Tom, Bel Elisabeth H. D.; Co-supervisor: van t Veer C.)
  • Yang Jack, Scicluna Brendon P, van Engelen Tjitske S R, Bonta Peter I, Majoor Christof J, van 't Veer Cornelis, de Vos Alex F, Bel Elisabeth H, van der Poll Tom Transcriptional changes in alveolar macrophages from adults with asthma after allergen challenge Allergy 2020 [PubMed]

2019

  • Schouten Laura R., van Kaam Anton H., Kohse Franziska, Veltkamp Floor, Bos Lieuwe D., de Beer Friso M., van Hooijdonk Roosmarijn T., Horn Janneke, Straat Marleen, Witteveen Esther, Glas Gerie J., Wieske Luuk, van Vught Lonneke A., Wiewel Maryse A., Ingelse Sarah A., Cortjens Bart, van Woensel Job B., Bos Albert P., Walther Thomas, Schultz Marcus J., Wösten-van Asperen Roelie M., de Beer Friso M., Bos Lieuwe D., Glas Gerie J., Horn Janneke, Hoogendijk Arie J., van Hooijdonk Roosmarijn T., Huson Mischa A., van der Poll Tom, Scicluna Brendon, Schouten Laura R., Schultz Marcus J., Straat Marleen, van Vught Lonneke A., Wieske Luuk, Wiewel Maryse A., Witteveen Esther, Bonten Marc J., Cremer Olaf L., Frencken Jos F., van de Groep Kirsten, Klein Klouwenberg Peter M., Koster-Brouwer Maria E., Ong David S., Verboom Diana M. Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study Annals of intensive care 2019;9 (1):55 [PubMed]
  • Opal Steven, File Thomas M., van der Poll Tom, Tzanis Evan, Chitra Surya, McGovern Paul C. An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic Clinical infectious diseases 2019;69 (1):S40-S47 [PubMed]
  • de Porto Alexander P., Liu Zhe, de Beer Regina, Florquin Sandrine, de Boer Onno J., Hendriks Rudi W., van der Poll Tom, de Vos Alex F. Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia Molecular medicine (Cambridge, Mass.) 2019;25 (1):3 [PubMed]
  • Yang Jack, Ramirez Moral Ivan, van 't Veer Cornelis, de Vos Alex F., de Beer Regina, Roelofs Joris J. T. H., Morgan B. Paul, van der Poll Tom Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model Respiratory research 2019;20 (1):165 [PubMed]
  • Rubio Ignacio, Osuchowski Marcin F., Shankar-Hari Manu, Skirecki Tomasz, Winkler Martin Sebastian, Lachmann Gunnar, la Rosée Paul, Monneret Guillaume, Venet Fabienne, Bauer Michael, Brunkhorst Frank M., Kox Matthijs, Cavaillon Jean-Marc, Uhle Florian, Weigand Markus A., Flohé Stefanie B., Wiersinga W. Joost, Martin-Fernandez Marta, Almansa Raquel, Martin-Loeches Ignacio, Torres Antoni, Giamarellos-Bourboulis Evangelos J., Girardis Massimo, Cossarizza Andrea, Netea Mihai G., van der Poll Tom, Scherag André, Meisel Christian, Schefold Joerg C., Bermejo-Martín Jesús F. Current gaps in sepsis immunology: new opportunities for translational research Lancet infectious diseases 2019;19 (12):e422-e436 [PubMed]
  • Seymour Christopher W., Kennedy Jason N., Wang Shu, Chang Chung-Chou H., Elliott Corrine F., Xu Zhongying, Berry Scott, Clermont Gilles, Cooper Gregory, Gomez Hernando, Huang David T., Kellum John A., Mi Qi, Opal Steven M., Talisa Victor, van der Poll Tom, Visweswaran Shyam, Vodovotz Yoram, Weiss Jeremy C., Yealy Donald M., Yende Sachin, Angus Derek C. Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis JAMA 2019 [PubMed]
  • van de Groep Kirsten, Verboom Diana M., van de Veerdonk Frank L., Haas Pieter-Jan A., van der Poll Tom, Schultz Marcus J., Bonten Marc J. M., Cremer Olaf L. Detection of invasive aspergillosis in critically ill patients with influenza: The role of plasma galactomannan American journal of respiratory and critical care medicine 2019;200 (5):636-638 [PubMed]
  • Iba Toshiaki, Levy Jerrold H., Warkentin Theodore E., Thachil Jecko, van der Poll Tom, Levi Marcel Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation Journal of thrombosis and haemostasis 2019;17 (11):1989-1994 [PubMed]
  • Pickkers Peter, van der Poll Tom Erratum: Correction to: What's new in immunostimulating strategies in the ICU (Intensive care medicine (2019) 45 1 (110-112)) Intensive care medicine 2019;45 (1):137 [PubMed]
  • Morales-Quinteros Luis, Schultz Marcus J., Bringué Josep, Calfee Carolyn S., Camprubí Marta, Cremer Olaf L., Horn Janneke, van der Poll Tom, Sinha Pratik, Artigas Antonio, Bos Lieuwe D., de Beer Friso M., Glas Gerie J., Hoogendijk Arie J., van Hooijdonk Roosmarijn T., Huson Mischa A., Scicluna Brendon, Schouten Laura R., Straat Marleen, van Vught Lonneke A., Wieske Luuk, Wiewel Maryse A., Witteveen Esther, Bonten Marc J., Frencken Jos F., van de Groep Kirsten, Klein Klouwenberg Peter M., Koster-Brouwer Maria E., Ong David S., Varkila Meri R., Verboom Diana M. Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS Annals of intensive care 2019;9 (1) [PubMed]
  • Leite Giuseppe Gianini Figuerêido, Scicluna Brendon P., van der Poll Tom, Salomão Reinaldo Genetic signature related to heme-hemoglobin metabolism pathway in sepsis secondary to pneumonia NPJ systems biology and applications 2019;5:26 [PubMed]
  • Perlee Desiree, de Vos Alex F., Scicluna Brendon P., Mancheño Pablo, de la Rosa Olga, Dalemans Wilfried, Nürnberg Peter, Lombardo Eleuterio, van der Poll Tom Human Adipose-Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae Stem cells translational medicine 2019;8 (8):785-796 [PubMed]
  • Schouten Laura R A, Bos Lieuwe D J, Serpa Neto A, van Vught Lonneke A, Wiewel Maryse A, Hoogendijk Arie J, Bonten Marc J M, Cremer Olaf L, Horn Janneke, van der Poll Tom, Schultz Marcus J, Wösten-van Asperen Roelie M Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response Intensive Care Medicine Experimental 2019;7 (1):58 [PubMed]
  • Hoogendijk Arie J., van Vught Lonneke A., Wiewel Maryse A., Fuhler Gwenny M., Belkasim-Bohoudi Hakima, Horn Janneke, Schultz Marcus J., Scicluna Brendon P., Peppelenbosch Maikel P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Kinase activity is impaired in neutrophils of sepsis patients Haematologica 2019;104 (6):e233-e235 [PubMed]
  • Yang Jack, van 't Veer Cornelis, Roelofs Joris J. T. H., van Heijst Jeroen W. J., de Vos Alex F., McCrae Keith R., Revenko Alexey S., Crosby Jeff, van der Poll Tom Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model American journal of physiology. Lung cellular and molecular physiology 2019;316 (1):L187-L196 [PubMed]
  • Khan Hina N., Perlee Desiree, Schoenmaker Lieke, van der Meer Anne-Jan, Franitza Marek, Toliat Mohammad Reza, Nürnberg Peter, Zwinderman Aeilko H., van der Poll Tom, Scicluna Brendon P. Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemia Journal of leukocyte biology 2019;106 (5):1153-1160 [PubMed]
  • Uhel Fabrice, Scicluna Brendon P., van Vught Lonneke A., Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom Matrix metalloproteinase-8: A useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission? Critical care (London, England) 2019;23 (1) [PubMed]
  • van de Groep Kirsten, Bos Martine P., Varkila Meri R. J., Savelkoul Paul H. M., Ong David S. Y., Derde Lennie P. G., Juffermans Nicole P., van der Poll Tom, Bonten Marc J. M., Cremer Olaf L., Schultz Marcus Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis European journal of clinical microbiology & infectious diseases 2019;38 (10):1829-1836 [PubMed]
  • Perlee Desiree Modulation of innate immunity during endotoxemia and gram-negative infection 2019. 212p. ISBN 9789463755115. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)
  • Frencken Jos F., van Baal Lottie, Kappen Teus H., Donker Dirk W., Horn Janneke, van der Poll Tom, van Klei Wilton A., Bonten Marc J. M., Cremer Olaf L., de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk, van Vught Lonneke A., Wiewel Maryse, Hoogendijk Arie J., Huson Mischa A., Scicluna Brendon, Schultz Marcus J., Ong David S. Y., Klein Klouwenberg Peter M. C., van de Groep Kirsten, Verboom Diana, Koster-Brouwer Maria E. Myocardial injury in critically Ill patients with community-acquired pneumonia a cohort study Annals of the American Thoracic Society 2019;16 (5):606-612 [PubMed]
  • van der Meer Anne Jan, Ding Chao, Hoogendijk Arie Johan, de Vos Alex F., Boon Louis, Zeerleder Sacha S., van der Poll Tom Neutrophils mitigate the systemic host response during endotoxemia in mice Immunology 2019;156 (3):277-281 [PubMed]
  • de Porto Alexander P. N. A., Claushuis Theodora A. M., van der Donk Lieve E. H., de Beer Regina, de Boer Onno J., Florquin Sandrine, Roelofs Joris J. T. H., Hendriks Rudi W., van der Poll Tom, van't Veer Cornelis, de Vos Alex F. Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis Thrombosis and haemostasis 2019;119 (6):930-940 [PubMed]
  • Claushuis Theodora A. M., de Vos Alex F., Roelofs Joris J. T. H., de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis Journal of innate immunity 2019;11 (2):168-180 [PubMed]
  • Claushuis Theodora A. M., van der Veen Annelou I. P., Horn Janneke, Schultz Marcus J., Houtkooper Riekelt H., van ’t Veer Cornelis, van der Poll Tom Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis Platelets 2019;30 (3):296-304 [PubMed]
  • Klein Klouwenberg Peter M. C., Spitoni Cristian, van der Poll Tom, Bonten Marc J., Cremer Olaf L., Frencken Jos F., van de Groep Kirsten, Koster-Brouwer Marlies E., Ong David S. Y., Verboom Diana, de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk, Hoogendijk Arie J., Huson Mischa A., van Vught Lonneke A., Schultz Marcus Predicting the clinical trajectory in critically ill patients with sepsis: A cohort study Critical care (London, England) 2019;23 (1) [PubMed]
  • van der Poll Tom Recombinant Human Soluble Thrombomodulin in Patients with Sepsis-Associated Coagulopathy: Another Negative Sepsis Trial? JAMA 2019;321 (20):1978-1980 [PubMed]
  • Verboom Diana M., Frencken Jos F., Ong David S. Y., Horn Janneke, van der Poll Tom, Bonten Marc J. M., Cremer Olaf L., Klein Klouwenberg Peter M. C. Robustness of sepsis-3 criteria in critically ill patients Journal of intensive care 2019;7 (1) [PubMed]
  • Perlee Desirée, de Vos Alex F., Scicluna Brendon P., Maag Anja, Mancheño Pablo, de la Rosa Olga, Dalemans Wilfried, Florquin Sandrine, van't Veer Cornelis, Lombardo Eleuterio, van der Poll Tom Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice STEM CELL RESEARCH & THERAPY 2019;10 (1) [PubMed]
  • Birnie Emma, Weehuizen Tassili A. F., Lankelma Jacqueline M., de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., Budding Andries E., de Vos Alex F., van der Poll Tom, Wiersinga W. Joost Role of Toll-Like Receptor 5 (TLR5) in Experimental Melioidosis Infection and immunity 2019;87 (8) [PubMed]
  • van der Meer Anne Jan, Kroeze Anna, Hoogendijk Arie J., Soussan Aicha Ait, Ellen van der Schoot C., Wuillemin Walter A., Voermans Carlijn, van der Poll Tom, Zeerleder Sacha Systemic inflammation induces release of cell-free DNA from hematopoietic and parenchymal cells in mice and humans Blood advances 2019;3 (5):724-728 [PubMed]
  • Domínguez-Andrés Jorge, Novakovic Boris, Li Yang, Scicluna Brendon P., Gresnigt Mark S., Arts Rob J.W., Oosting Marije, Moorlag Simone J.C.F.M., Groh Laszlo A., Zwaag Jelle, Koch Rebecca M., ter Horst Rob, Joosten Leo A.B., Wijmenga Cisca, Michelucci Alessandro, van der Poll Tom, Kox Matthijs, Pickkers Peter, Kumar Vinod, Stunnenberg Henk, Netea Mihai G. The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity Cell metabolism 2019;29 (1):211-220.e5 [PubMed]
  • de Porto Alexander P. N. A. The role of Bruton’s tyrosine kinase and the spleen in host defense against bacterial pathogens: Two essential gears in the immune clockwork 2019. 253p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: de Vos A. F. , van 't Veer C.)
  • Birnie Emma, Claushuis Theodora A. M., Koh Gavin C. K. W., Limmathurotsakul Direk, Day Nicholas P. J., Roelofs Joris J. T. H., Ware Jerry, Hou Baidong, de Vos Alex F., van der Poll Tom, van't Veer Cornelis, Wiersinga W. Joost Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis) Journal of infectious diseases 2019;219 (4):648-659 [PubMed]
  • Bos Lieuwe D J, Scicluna Brendon P, Ong David S Y, Cremer Olaf, van der Poll Tom, Schultz Marcus J Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles American journal of respiratory and critical care medicine 2019;200 (1):42-50 [PubMed]
  • Pickkers Peter, van der Poll Tom “What’s new?”: Immunostimulating strategies in the ICU Intensive care medicine 2019;45 (1):110-112 [PubMed]

2018

  • Scicluna Brendon P., Wiewel Maryse A., van Vught Lonneke A., Hoogendijk Arie J., Klarenbeek Augustijn M., Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Horn Janneke, Bonten Marc J., Schultz Marcus J., Cremer Olaf L., van der Poll Tom A Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis Upon Intensive Care Unit Admission American journal of respiratory and critical care medicine 2018;197 (8):1070-1073 [PubMed]
  • van der Poll Tom, van de Veerdonk Frank L., Scicluna Brendon P., Netea Mihai G. Are histones real pathogenic agents in sepsis? Nature reviews. Immunology 2018;18 (2):148 [PubMed]
  • van Lieshout Miriam H. P., de Vos Alex F., Dessing Mark C., de Porto Alexander P. N. A., de Boer Onno J., de Beer Regina, Terpstra Sanne, Florquin Sandrine, van't Veer Cornelis, van der Poll Tom ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice European journal of immunology 2018;48 (1):66-79 [PubMed]
  • van Engelen Tjitske S. R., Wiersinga Willem Joost, Scicluna Brendon P., van der Poll Tom Biomarkers in Sepsis Critical care clinics 2018;34 (1):139-+ [PubMed]
  • van de Groep Kirsten, Bos Martine P., Savelkoul Paul H. M., Rubenjan Anna, Gazenbeek Christel, Melchers Willem J. G., van der Poll Tom, Juffermans Nicole P., Ong David S. Y., Bonten Marc J. M., Cremer Olaf L. Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis European journal of clinical microbiology & infectious diseases 2018;37 (7):1333-1344 [PubMed]
  • van de Groep Kirsten, Nierkens Stefan, Cremer Olaf L, Peelen Linda M, Klein Klouwenberg Peter M C, Schultz Marcus J, Hack C Erik, van der Poll Tom, Bonten Marc J M, Ong David S Y Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study Critical care (London, England) 2018;22 (1):348 [PubMed]
  • Boerekamps Anne, Newsum Astrid M., Smit Colette, Arends Joop E., Richter Clemens, Reiss Peter, Rijnders Bart J. A., Brinkman Kees, van der Valk Marc, Study group members AMC , Geerlings Suzanne E., Godfried Mieke H., Goorhuis Abraham, Hovius Joppe W. R., van der Meer Johannes T. M., Kuijpers Taco W., Nellen Francisca J. B., van der Poll Tom, Prins Jan M., van Vugt H. J. M. , Wiersinga Willem J., Wit Ferdinand W. N. M. High treatment uptake in HIV/HCV-coinfected patients after unrestricted access to direct-acting antivirals in the Netherlands Clinical infectious diseases 2018;66 (9):1352-1359 [PubMed]
  • Stroo Ingrid, Ding Chao, Novak Andreja, Yang Jack, Roelofs Joris J. T. H., Meijers Joost C. M., Revenko Alexey S., van ’t Veer Cornelis, Zeerleder Sacha, Crosby Jeff R., van der Poll Tom Inhibition of the extrinsic or intrinsic coagulation pathway during pneumonia-derived sepsis American journal of physiology. Lung cellular and molecular physiology 2018;315 (5):L799-L809 [PubMed]
  • Uhel Fabrice, Peters-Sengers Hessel, van der Poll Tom Initiation of renal replacement therapy in patients with sepsis: more to it than meets the eye Annals of translational medicine 2018;6 (Suppl 2):S130 [PubMed]
  • Perlee Desiree, van Vught Lonneke A., Scicluna Brendon P., Maag Anja, Lutter René, Kemper Elles M., van ‘t Veer Cornelis, Punchard Marie A., González Jesús, Richard Marie Paule, Dalemans Wilfried, Lombardo Eleuterio, de Vos Alex F., van der Poll Tom Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single-Blind, Parallel Group, Placebo Controlled Trial Stem cells (Dayton, Ohio) 2018;36 (11):1778-1788 [PubMed]
  • Boshuizen Margit, Binnekade Jan M., Nota Benjamin, van de Groep Kirsten, Cremer Olaf L., Tuinman Pieter R., Horn Janneke, Schultz Marcus J., van Bruggen Robin, Juffermans Nicole P., de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk, Hoogendijk Arie J., Huson Mischa A., Scicluna Brendon P., van der Poll Tom, van Vught Lonneke A., Wiewel Maryse A., Bonten Marc J. M., Frencken Jos F., Klein Klouwenberg Peter M. C., Koster-Brouwer Maria E., Ong David S. Y., Verboom Diana M. Iron metabolism in critically ill patients developing anemia of inflammation: a case control study Annals of intensive care 2018;8 (1) [PubMed]
  • Ding Chao, van 't Veer Cornelis, Roelofs Joris J. T. H., Shukla Meenal, McCrae Keith R., Revenko Alexey S., Crosby Jeff, van der Poll Tom Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis American journal of physiology. Lung cellular and molecular physiology 2018;314 (3):L397-L405 [PubMed]
  • Simonis Fabienne D., de Iudicibus Gianfranco, Cremer Olaf L., Ong David S. Y., van der Poll Tom, Bos Lieuwe D., Schultz Marcus J. Macrolide therapy is associated with reduced mortality in acute respiratory distress syndrome (ARDS) patients Annals of translational medicine 2018;6 (2):24 [PubMed]
  • Smolders E. J., Smit C., de Kanter C. T. M. M., Dofferhoff A. S. M., Arends J. E., Brinkman K., Rijnders B., van der Valk M., Reiss P., Burger D. M., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Wiersinga W. J., Goorhuis A., Hovius J. W., Bijsterveld M. A. H., van Eden J., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Weijsenfeld A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., Hage de Looff L., Wintermans B., Veenemans J., Pronk M. J. H., Ammerlaan H. S. M., de Munnik E. S., Langebeek N., van Wijk M., Vandenbroucke-Grauls C. M. J. E. Management of drug interactions with direct-acting antivirals in Dutch HIV/hepatitis C virus-coinfected patients: adequate but not perfect HIV medicine 2018;19 (3):216-226 [PubMed]
  • Hoogland Inge C. M., Westhoff Dunja, Engelen-Lee Joo-Yeon, Melief Jeroen, Valls Serón Mercedes, Houben-Weerts Judith H. M. P., Huitinga Inge, van Westerloo David J., van der Poll Tom, van Gool Willem A., van de Beek Diederik Microglial activation after systemic stimulation with lipopolysaccharide and Escherichia coli Frontiers in cellular neuroscience 2018;12 [PubMed]
  • Mason Lauren M. K., Coumou Jeroen, Ersöz Jasmin I., Oei Anneke, Roelofs Joris J. T. H., Vogl Thomas, van der Poll Tom, Hovius Joppe W. R. MRP8/14 does not contribute to dissemination or inflammation in a murine model of Lyme borreliosis Immunobiology 2018;223 (11):694-698 [PubMed]
  • Frencken Jos F., Donker Dirk W., Spitoni Cristian, Koster-Brouwer Marlies E., Soliman Ivo W., Ong David S. Y., Horn Janneke, van der Poll Tom, van Klei Wilton A., Bonten Marc J. M., Cremer Olaf L. Myocardial Injury in Patients With Sepsis and Its Association With Long-Term Outcome Circulation. Cardiovascular quality and outcomes 2018;11 (2):UNSP e004040 [PubMed]
  • Claushuis Theodora A. M., de Stoppelaar Sacha F., de Vos Alex F., Grootemaat Anita E., van der Wel Nicole N., Roelofs Joris J. T. H., Ware Jerry, van't Veer Cornelis, van der Poll Tom Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis Arteriosclerosis, thrombosis, and vascular biology 2018;38 (8):1772-1784 [PubMed]
  • Tumlin James A, Murugan Raghavan, Deane Adam M, Ostermann Marlies, Busse Laurence W, Ham Kealy R, Kashani Kianoush, Szerlip Harold M, Prowle John R, Bihorac Azra, Finkel Kevin W, Zarbock Alexander, Forni Lui G, Lynch Shannan J, Jensen Jeff, Kroll Stew, Chawla Lakhmir S, Tidmarsh George F, Bellomo Rinaldo, Study group members AMC , van der Poll Tom Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II Critical care medicine 2018;46 (6):949-957 [PubMed]
  • van Engelen Tjitske S. R., Wiersinga W. Joost, van der Poll Tom Pathogenesis of sepsisin: Handbook of Sepsis. Springer International Publishing; 2018. p. 31-43, ISBN 9783319735054
  • De Francesco Davide, Verboeket Sebastiaan O, Underwood Jonathan, Bagkeris Emmanouil , Wit Ferdinand W, Mallon Patrick W G, Winston Alan, Reiss Peter, Sabin Caroline A, Study group members AMC , Reiss P. , Wit F. W. N. M., Kooij K. W., van Zoest R. A. , Verheij E. , Verboeket Sebastiaan O., Prins M. , Kootstra N. A., Harskamp-Holwerda A. M. , Maurer Irma, Mangas Ruiz M. M., Boeser-Nunnink B. D. M. , Geerlings S. E. , Goorhuis A. , Hovius J. W. R. , Nellen F. J. B. , van der Poll Tom, Prins J. M. , Wiersinga W. J. , van Vugt M. , de Bree G. J. , Postema P. G. , Bisschop P. H. L. T., Serlie M. J. M. , Dekker E. , van der Velde N. , Willemsen J. M. R., Vogt L. , Portegies P. , Schmand B. A. , Geurtsen G. J. , Verbraak F. D. , Visser I. , Nieuwkerk P. T. , Majoie C. B. L. M. , Caan M. W. A. , van Lunsen H. W. , van den Born B. J. H. , Stroes E. S. G. Patterns of co-occurring comorbidities in people living with HIV Open forum infectious diseases 2018;5 (11):ofy272 [PubMed]
  • Claushuis Theodora A. M., de Vos Alex F., Nieswandt Bernard, Boon Louis, Roelofs Joris J. T. H., de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria Blood 2018;131 (8):864-876 [PubMed]
  • van den Boogaard Florry E., Brands Xanthe, Duitman JanWillem, de Stoppelaar Sacha F., Borensztajn Keren S., Roelofs Joris J. T. H., Hollenberg Morley D., Spek C. Arnold, Schultz Marcus J., van ‘t Veer Cornelis, van der Poll Tom Protease-activated receptor 2 facilitates bacterial dissemination in pneumococcal pneumonia Journal of infectious diseases 2018;217 (9):1462-1471 [PubMed]
  • Waasdorp Maaike Protease-activated receptors in diabetic nephropathy and renal fibrosis 2018. ISBN 9789463800709. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Florquin S.; Co-supervisors: Spek C. A., Duitman J. W.)
  • Claushuis Theodora A. M., van der Donk Lieve E. H., Luitse Anna L., van Veen Henk A., van der Wel Nicole N., van Vught Lonneke A., Roelofs Joris J. T. H., de Boer Onno J., Lankelma Jacqueline M., Boon Louis, de Vos Alex F., van't Veer Cornelis, van der Poll Tom Role of peptidylarginine deiminase 4 in neutrophil extracellular trap formation and host defense during klebsiella pneumoniae-induced pneumonia-derived sepsis Journal of immunology (Baltimore, Md. 2018;201 (4):1241-1252 [PubMed]
  • Wiewel Maryse A., Scicluna Brendon P., van Vught Lonneke A., Hoogendijk Arie J., Zwinderman Aeilko H., Lutter René, Horn Janneke, Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom The host response in critically ill sepsis patients on statin therapy: a prospective observational study Annals of intensive care 2018;8 (1):9 [PubMed]
  • Claushuis Theodora A. M. The role of platelets in sepsis 2018. ISBN 9789090309743. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., de Vos A. F.)
  • Harris Vanessa C. The role of the intestinal microbiome in rotavirus vaccine immunogenicity: exploration from correlation to causation 2018. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wiersinga W. J., Boele van Hensbroek M.; Co-supervisors: van der Poll T., Giaquinto C.)
  • Miller Russell R., Lopansri Bert K., Burke John P., Levy Mitchell, Opal Steven, Rothman Richard E., D'Alessio Franco R., Sidhaye Venkataramana K., Aggarwal Neil R., Balk Robert, Greenberg Jared A., Yoder Mark, Patel Gourang, Gilbert Emily, Afshar Majid, Parada Jorge P., Martin Greg S., Esper Annette M., Kempker Jordan A., Narasimhan Mangala, Tsegaye Adey, Hahn Stella, Mayo Paul, van der Poll Tom, Schultz Marcus J., Scicluna Brendon P., Klouwenberg Peter Klein, Rapisarda Antony, Seldon Therese A., McHugh Leo C., Yager Thomas D., Cermelli Silvia, Sampson Dayle, Rothwell Victoria, Newman Richard, Bhide Shruti, Fox Brian A., Kirk James T., Navalkar Krupa, Davis Roy F., Brandon Roslyn A., Brandon Richard B. Validation of a host response assay, SeptiCyte LAB, for discriminating sepsis from systemic inflammatory response syndrome in the ICU American journal of respiratory and critical care medicine 2018;198 (7):903-913 [PubMed]
  • Koster-Brouwer Maria E., Verboom Diana M., Scicluna Brendon P., van de Groep Kirsten, Frencken Jos F., Janssen Davy, Schuurman Rob, Schultz Marcus J., van der Poll Tom, Bonten Marc J. M., Cremer Olaf L., de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., Hoogendijk Arie J., van Hooijdonk Roosmarijn T. M., Horn Janneke, Huson Mischa A., Klein Klouwenberg Peter M. C., Ong David S. Y., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wieske Luuk, Wiewel Maryse A., Witteveen Esther Validation of a Novel Molecular Host Response Assay to Diagnose Infection in Hospitalized Patients Admitted to the ICU With Acute Respiratory Failure Critical care medicine 2018;46 (3):368-374 [PubMed]

2017

  • Netea Mihai G., Balkwill Frances, Chonchol Michel, Cominelli Fabio, Donath Marc Y., Giamarellos-Bourboulis Evangelos J., Golenbock Douglas, Gresnigt Mark S., Heneka Michael T., Hoffman Hal M., Hotchkiss Richard, Joosten Leo A. B., Kastner Daniel L., Korte Martin, Latz Eicke, Libby Peter, Mandrup-Poulsen Thomas, Mantovani Alberto, Mills Kingston H. G., Nowak Kristen L., O'Neill Luke A., Pickkers Peter, van der Poll Tom, Ridker Paul M., Schalkwijk Joost, Schwartz David A., Siegmund Britta, Steer Clifford J., Tilg Herbert, van der Meer Jos W. M., van de Veerdonk Frank L., Dinarello Charles A. A guiding map for inflammation Nature immunology 2017;18 (8):826-831 [PubMed]
  • Lankelma Jacqueline M., Cranendonk Duncan R., Belzer Clara, de Vos Alex F., de Vos Willem M., van der Poll Tom, Wiersinga W. Joost Antibiotic-induced gut microbiota disruption during human endotoxemia: a randomised controlled study Gut 2017;66 (9):1623-1630 [PubMed]
  • Frencken Jos F., van Vught Lonneke A., Peelen Linda M., Ong David S. Y., Klein Klouwenberg Peter M. C., Horn Janneke, Bonten Marc J. M., van der Poll Tom, Cremer Olaf L., de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Hoogendijk Arie J., Huson Mischa A., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk An Unbalanced Inflammatory Cytokine Response Is Not Associated With Mortality Following Sepsis: A Prospective Cohort Study Critical care medicine 2017;45 (5):e493-e499 [PubMed]
  • Huson Michaëla A. M., Katete Chawezi, Chunda Lilian, Ngoma Jonathan, Wallrauch Claudia, Heller Tom, van der Poll Tom, Grobusch Martin P. Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi Infection 2017;45 (6):893-896 [PubMed]
  • van Vught Lonneke A., Scicluna Brendon P., Wiewel Maryse A., Hoogendijk Arie J., Klein Klouwenberg Peter M. C., Ong David S. Y., Cremer Olaf L., Horn Janneke, Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Bonten Marc M. J., Schultz Marcus J., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Frencken Jos F., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Huson Michaëla A. M., Schouten Laura R. A., Straat Marleen, Wieske Luuk, Witteveen Esther Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients Critical care medicine 2017;45 (11):1854-1862 [PubMed]
  • Anas Adam A. Cell-specific innate immunity in lung infection and inflammation 2017. 152p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: de Vos A. F., van 't Veer C.)
  • Scicluna Brendon P., van Vught Lonneke A., Zwinderman Aeilko H., Wiewel Maryse A., Davenport Emma E., Burnham Katie L., Nürnberg Peter, Schultz Marcus J., Horn Janneke, Cremer Olaf L., Bonten Marc J., Hinds Charles J., Wong Hector R., Knight Julian C., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Frencken Jos F., Koster-Brouwer Maria E., van de Groep Kirsten, Verboom Diana M., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Hoogendijk Arie J., Huson Mischa A., Klouwenberg Peter M. Klein, Ong David S. Y., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study lancet. Respiratory medicine 2017;5 (10):816-826 [PubMed]
  • Cranendonk Duncan R., van Vught Lonneke A., Wiewel Maryse A., Cremer Olaf L., Horn Janneke, Bonten Marc J., Schultz Marcus J., van der Poll Tom, Wiersinga W. Joost Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care JAMA dermatology 2017;153 (6):578-582 [PubMed]
  • Levi Marcel, van der Poll Tom Coagulation and sepsis Thrombosis research 2017;149:38-44 [PubMed]
  • Stroo Ingrid, Zeerleder Sacha, Ding Chao, Luken Brenda M., Roelofs Joris J. T. H., de Boer Onno J., Meijers Joost C. M., Castellino Francis J., van 't Veer Cornelis, van der Poll Tom Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation Thrombosis and haemostasis 2017;117 (8):1601-1614 [PubMed]
  • Lankelma Jacqueline M., van Vught Lonneke A., Belzer Clara, Schultz Marcus J., van der Poll Tom, de Vos Willem M., Wiersinga W. Joost Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study Intensive care medicine 2017;43 (1):59-68 [PubMed]
  • van Vught Lonneke A., Holman Rebecca, de Jonge Evert, de Keizer Nicolette F., van der Poll Tom Diabetes Is Not Associated With Increased 90-Day Mortality Risk in Critically Ill Patients With Sepsis Critical care medicine 2017;45 (10):E1026-E1035 [PubMed]
  • Ong David S. Y., Bonten Marc J. M., Spitoni Cristian, Verduyn Lunel Frans M., Frencken Jos F., Horn Janneke, Schultz Marcus J., van der Poll Tom, Klein Klouwenberg Peter M. C., Cremer Olaf L. Epidemiology of Multiple Herpes Viremia in Previously Immunocompetent Patients With Septic Shock Clinical infectious diseases 2017;64 (9):1204-1210 [PubMed]
  • Anas Adam A., Claushuis Theodora A. M., Mohan Rajiv A., Christoffels Vincent M., Aidinis Vassilis, Florquin Sandrine, van't Veer Cornelis, Hou Baidong, de Vos Alex F., van der Poll Tom Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia American journal of respiratory cell and molecular biology 2017;56 (5):648-656 [PubMed]
  • García-Laorden M. Isabel, Stroo Ingrid, Terpstra Sanne, Florquin Sandrine, Medema Jan Paul, van T Veer Cornelis, de Vos Alex F., van der Poll Tom Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis Mediators of inflammation 2017;2017:4137563 [PubMed]
  • de Jong Hanna K., Garcia-Laorden Maria Isabel, Hoogendijk Arie J., Parry Christopher M., Maude Rapeephan R., Dondorp Arjen M., Faiz Mohammed Abul, van der Poll Tom, Wiersinga Willem Joost Expression of intra- and extracellular granzymes in patients with typhoid fever PLoS neglected tropical diseases 2017;11 (7):e0005823 [PubMed]
  • Stroo Ingrid, Yang Jack, de Boer Johannes Daan, Roelofs Joris J. T. H., van 't Veer Cornelis, Castellino Francis J., Zeerleder Sacha, van der Poll Tom Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII American journal of physiology. Lung cellular and molecular physiology 2017;312 (2):L163-L171 [PubMed]
  • Anas A. A., Yang J., Daan de Boer J., Roelofs J. J. T. H., Hou B., de Vos A. F., van der Poll T. General, but not myeloid or type II lung epithelial cell, myeloid differentiation factor 88 deficiency abrogates house dust mite induced allergic lung inflammation Clinical and experimental immunology 2017;187 (2):204-212 [PubMed]
  • Janssen Saskia, Schutz Charlotte, Ward Amy M., Huson Mischa A. M., Wilkinson Robert J., Burton Rosie, Maartens Gary, Wilkinson Katalin A., Meijers Joost C. M., Lutter René, Grobusch Martin P., Meintjes Graeme, van der Poll Tom Hemostatic Changes Associated With Increased Mortality Rates in Hospitalized Patients With HIV-Associated Tuberculosis: A Prospective Cohort Study Journal of infectious diseases 2017;215 (2):247-258 [PubMed]
  • Janssen Saskia, Huson Michaela Am, Osbak Kara K., Rossatanga Elie-Gide, Alabi Abraham, Lutter René, Grobusch Martin P., van der Poll Tom HIV infection rather than concurrent opportunistic infections drives most systemic procoagulant, vascular and damage responses - a prospective cohort study in central Africa Antiviral therapy 2017;22 (2):153-161 [PubMed]
  • Bartelsman M., Joore I. K., van Bergen J. E., Hogewoning A. A., Zuure F. R., van Veen M. G., Deug F., Heidenrijk M., Prins J. M., Prins M. [= Maria], Smit P. J., van der Valk M., Reiss P., de Bree G. J., Hoornenborg E., Davidovich U., Geerlings S. E., Oomen A., van sighem A., Zuilhof W., Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Berkhout B., Berretty B., Bezemer D., Blok W. L., Bomers M., Boucher C. A. B., Brokking W., Burger D., Brinkman K., de Bruin M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., van der Helm J. J., Hovius J. W., Kootstra N. A., van der Meer J. T., Nellen F. J., Pasternak A. O., van der Poll T., van Rooijen M. S., de Vries H. J., van Vugt M., Wiersinga W. J., Wit F. W. HIV testing week 2015: lowering barriers for HIV testing among high-risk groups in Amsterdam BMC infectious diseases 2017;17 (1):529 [PubMed]
  • Wiewel Maryse A. Host response and outcome of sepsis in the critically ill 2017. 209p. ISBN 9789462955585. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Schultz M. J.)
  • Stroo Ingrid, Yang Jack, Anas Adam A., de Boer J. Daan, van Mierlo Gerard, Roem Dorina, Wouters Diana, Engel Ruchira, Roelofs Joris J. T. H., van 't Veer Cornelis, van der Poll Tom, Zeerleder Sacha Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice PLoS ONE 2017;12 (10):e0186652 [PubMed]
  • Bos L. D., Schouten L. R., van Vught L. A., Wiewel M. A., Ong D. S. Y., Cremer O., Artigas A., Martin-Loeches I., Hoogendijk A. J., van der Poll T., Horn J., Juffermans N., Calfee C. S., Schultz M. J., Frencken Jos F., Bonten Marc, Klein Klouwenberg Peter M. C., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Straat Marleen, Witteveen Esther, Glas Gerie J., Wieske Luuk, Scicluna Brendon P., Belkasim-Bohoudi H. Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis Thorax 2017;72 (10):876-883 [PubMed]
  • Janssen Saskia Improving management of HIV-infected patients in Africa 2017. 263p. ISBN 9789402804843. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Grobusch M., van der Poll T.; Co-supervisors: van Vugt M., Meintjes G.)
  • Klein Klouwenberg Peter M. C., Frencken Jos F., Kuipers Sanne, Ong David S. Y., Peelen Linda M., van Vught Lonneke A., Schultz Marcus J., van der Poll Tom, Bonten Marc J., Cremer Olaf L. Incidence, Predictors, and Outcomes of New-Onset Atrial Fibrillation in Critically Ill Patients with Sepsis. A Cohort Study American journal of respiratory and critical care medicine 2017;195 (2):205-211 [PubMed]
  • Witteveen Esther, Wieske Luuk, van der Poll Tom, van der Schaaf Marike, van Schaik Ivo N., Schultz Marcus J., Verhamme Camiel, Horn Janneke, de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Hoogendijk Arie J., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A. Increased Early Systemic Inflammation in ICU-Acquired Weakness; A Prospective Observational Cohort Study Critical care medicine 2017;45 (6):972-979 [PubMed]
  • Birnie Emma, Koh Gavin C. K. W., Löwenberg Ester C., Meijers Joost C. M., Maude Rapeephan R., Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga W. Joost Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis PLoS neglected tropical diseases 2017;11 (3) [PubMed]
  • Ellenbroek Guilielmus H. J. M., van Puijvelde Gijs H. M., Anas Adam A., Bot Martine, Asbach Miriam, Schoneveld Arjan, van Santbrink Peter J., Foks Amanda C., Timmers Leo, Doevendans Pieter A., Pasterkamp Gerard, Hoefer Imo E., van der Poll Tom, Kuiper Johan, de Jager Saskia C. A. Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness Scientific reports 2017;7:42688 [PubMed]
  • Janssen S., Osbak K., Holman R., Hermans S., Moekotte A., Knap M., Rossatanga E., Massinga-Loembe M., Alabi A., Adegnika A., Meenken C., van Vugt M., Kremsner P. G., Meintjes G., van der Poll T., Grobusch M. P. Low incidence of the immune reconstitution inflammatory syndrome among HIV-infected patients starting antiretroviral therapy in Gabon: a prospective cohort study Infection 2017;45 (5):669-676 [PubMed]
  • Janssen Saskia, Schutz Charlotte, Ward Amy, Nemes Elisa, Wilkinson Katalin A., Scriven James, Huson Mischa A., Aben Nanne, Maartens Gary, Burton Rosie, Wilkinson Robert J., Grobusch Martin P., van der Poll Tom, Meintjes Graeme Mortality in Severe Human Immunodeficiency Virus-Tuberculosis Associates With Innate Immune Activation and Dysfunction of Monocytes Clinical infectious diseases 2017;65 (1):73-82 [PubMed]
  • van der Poll Tom Myeloid-derived Suppressor Cells in Sepsis American journal of respiratory and critical care medicine 2017;196 (3):256-258 [PubMed]
  • van den Boogaard Florry E., Hofstra Jorrit J., Brands Xanthe, Levi Marcel M., Roelofs Joris J. T. H., Zaat Sebastiaan A. J., van't Veer Cornelis, van der Poll Tom, Schultz Marcus J. Nebulized Recombinant Human Tissue Factor Pathway Inhibitor Attenuates Coagulation and Exerts Modest Anti-inflammatory Effects in Rat Models of Lung Injury Journal of aerosol medicine and pulmonary drug delivery 2017;30 (2):91-99 [PubMed]
  • van der Meer Anne Jan, Zeerleder Sacha, Blok Dana C., Kager Liesbeth M., Lede Ivar O., Rahman Wahid, Afroz Rumana, Ghose Aniruddha, Visser Caroline E., Zahed Abu Shahed Md, Husain Md Anwar, Alam Khan Mashrequl, Barua Pravat Chandra, Hassan Mahtabuddin, Tayab Md Abu, Dondorp Arjen M., van der Poll Tom Neutrophil extracellular traps in patients with pulmonary tuberculosis Respiratory research 2017;18 (1):181 [PubMed]
  • Wiewel M. A., van Vught L. A., van der Poll T., Schultz M. J. Patient-related determinants of host response and sepsis outcome Netherlands journal of critical care 2017;25 (5):159-164
  • Huson Michaëla A. M., Kalkman Rachel, Grobusch Martin P., van der Poll Tom Predictive value of the qSOFA score in patients with suspected infection in a resource limited setting in Gabon Travel medicine and infectious disease 2017;15:76-77 [PubMed]
  • Wiewel Maryse A., van Vught Lonneke A., Scicluna Brendon P., Hoogendijk Arie J., Frencken Jos F., Zwinderman Aeilko H., Horn Janneke, Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Klein Klouwenberg Peter M. C., Ong David S. Y., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk Prior Use of Calcium Channel Blockers Is Associated With Decreased Mortality in Critically Ill Patients With Sepsis: A Prospective Observational Study Critical care medicine 2017;45 (3):454-463 [PubMed]
  • Trauer James, Muhi Stephen, McBryde Emma S., Al Harbi Shmeylan A., Arabi Yaseen M., Boyle Andrew J., Cartin-Ceba Rodrigo, Chen Wei, Chen Yung-Tai, Falcone Marco, Gajic Ognjen, Godsell Jack, Gong Michelle Ng, Kor Daryl, Lösche Wolfgang, McAuley Daniel F., O'Neal Hollis R., Osthoff Michael, Otto Gordon P., Sossdorf Maik, Tsai Min-Juei, Valerio-Rojas Juan C., van der Poll Tom, Violi Francesco, Ware Lorraine, Widmer Andreas F., Wiewel Maryse A., Winning Johannes, Eisen Damon P. Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching Critical care medicine 2017;45 (11):1871-1879 [PubMed]
  • Pisani Luigi, Roozeman Jan-Paul, Simonis Fabienne D., Giangregorio Antonio, van der Hoeven Sophia M., Schouten Laura R., Horn Janneke, Serpa Neto Ary, Festic Emir, Dondorp Arjen M., Grasso Salvatore, Bos Lieuwe D., Schultz Marcus J., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., Wieske Luuk, Frencken Jos F., Bonten Marc, Klein Klouwenberg Peter M. C., Ong David, Scicluna Brendon P., Hoogendijk Arjan J., Belkasim-Bohoudi H., van der Poll Tom Risk stratification using SpO2/FiO2 and PEEP at initial ARDS diagnosis and after 24 h in patients with moderate or severe ARDS Annals of intensive care 2017;7 (1) [PubMed]
  • Jaeger Veronika K., Hoffman Hal M., van der Poll Tom, Tilson Hugh, Seibert Julia, Speziale Antonio, Junge Guido, Franke Kristina, Vritzali Eleni, Hawkins Philip N., Kuemmerle-Deschner Jasmin, Walker Ulrich A. Safety of vaccinations in patients with cryopyrin-associated periodic syndromes: a prospective registry based study Rheumatology (Oxford, England) 2017;56 (9):1484-1491 [PubMed]
  • Wiersinga W. J., van Zanten A. R. H., Kaasjager K. A., van der Poll T. Sepsis: nieuwe inzichten, nieuwe definitie Nederlands tijdschrift voor geneeskunde 2017;161:D1551 [PubMed]
  • Hoogendijk Arie J., Garcia-Laorden M. Isabel, van Vught Lonneke A., Wiewel Maryse A., Belkasim-Bohoudi Hakima, Duitman Janwillem, Horn Janneke, Schultz Marcus J., Scicluna Brendon P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Sepsis Patients Display a Reduced Capacity to Activate Nuclear Factor-κB in Multiple Cell Types Critical care medicine 2017;45 (5):e524-e531 [PubMed]
  • Ong David S. Y., Frencken Jos F., Klein Klouwenberg Peter M. C., Juffermans Nicole, van der Poll Tom, Bonten Marc J. M., Cremer Olaf L. Short-Course Adjunctive Gentamicin as Empirical Therapy in Patients With Severe Sepsis and Septic Shock: A Prospective Observational Cohort Study Clinical infectious diseases 2017;64 (12):1731-1736 [PubMed]
  • van der Poll Tom, Opal Steven M. Should all septic patients be given systemic anticoagulation? No Intensive care medicine 2017;43 (3):455-457 [PubMed]
  • Rhodes Andrew, Evans Laura E., Alhazzani Waleed, Levy Mitchell M., Antonelli Massimo, Ferrer Ricard, Kumar Anand, Sevransky Jonathan E., Sprung Charles L., Nunnally Mark E., Rochwerg Bram, Rubenfeld Gordon D., Angus Derek C., Annane Djillali, Beale Richard J., Bellinghan Geoffrey J., Bernard Gordon R., Chiche Jean-Daniel, Coopersmith Craig, de Backer Daniel P., French Craig J., Fujishima Seitaro, Gerlach Herwig, Hidalgo Jorge Luis, Hollenberg Steven M., Jones Alan E., Karnad Dilip R., Kleinpell Ruth M., Koh Younsuk, Lisboa Thiago Costa, Machado Flavia R., Marini John J., Marshall John C., Mazuski John E., McIntyre Lauralyn A., McLean Anthony S., Mehta Sangeeta, Moreno Rui P., Myburgh John, Navalesi Paolo, Nishida Osamu, Osborn Tiffany M., Perner Anders, Plunkett Colleen M., Ranieri Marco, Schorr Christa A., Seckel Maureen A., Seymour Christopher W., Shieh Lisa, Shukri Khalid A., Simpson Steven Q., Singer Mervyn, Thompson B. Taylor, Townsend Sean R., van der Poll Thomas, Vincent Jean-Louis, Wiersinga W. Joost, Zimmerman Janice L., Dellinger R. Phillip Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Intensive care medicine 2017;43 (3):304-377 [PubMed]
  • Rhodes Andrew, Evans Laura E., Alhazzani Waleed, Levy Mitchell M., Antonelli Massimo, Ferrer Ricard, Kumar Anand, Sevransky Jonathan E., Sprung Charles L., Nunnally Mark E., Rochwerg Bram, Rubenfeld Gordon D., Angus Derek C., Annane Djillali, Beale Richard J., Bellinghan Geoffrey J., Bernard Gordon R., Chiche Jean-Daniel, Coopersmith Craig, de Backer Daniel P., French Craig J., Fujishima Seitaro, Gerlach Herwig, Hidalgo Jorge Luis, Hollenberg Steven M., Jones Alan E., Karnad Dilip R., Kleinpell Ruth M., Koh Younsuck, Lisboa Thiago Costa, Machado Flavia R., Marini John J., Marshall John C., Mazuski John E., McIntyre Lauralyn A., McLean Anthony S., Mehta Sangeeta, Moreno Rui P., Myburgh John, Navalesi Paolo, Nishida Osamu, Osborn Tiffany M., Perner Anders, Plunkett Colleen M., Ranieri Marco, Schorr Christa A., Seckel Maureen A., Seymour Christopher W., Shieh Lisa, Shukri Khalid A., Simpson Steven Q., Singer Mervyn, Thompson B. Taylor, Townsend Sean R., van der Poll Thomas, Vincent Jean-Louis, Wiersinga W. Joost, Zimmerman Janice L., Dellinger R. Phillip Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Critical care medicine 2017;45 (3):486-552 [PubMed]
  • Lankelma Jacqueline M., Birnie Emma, Weehuizen Tassili A. F., Scicluna Brendon P., Belzer Clara, Houtkooper Riekelt H., Roelofs Joris J. T. H., de Vos Alex F., van der Poll Tom, Budding Andries E., Wiersinga W. Joost The gut microbiota as a modulator of innate immunity during melioidosis PLoS neglected tropical diseases 2017;11 (4):e0005548 [PubMed]
  • van Vught Lonneke A., Wiewel Maryse A., Hoogendijk Arie J., Frencken Jos F., Scicluna Brendon P., Klein Klouwenberg Peter M. C., Zwinderman Aeilko H., Lutter Rene, Horn Janneke, Schultz Marcus J., Bonten Marc M. J., Cremer Olaf L., van der Poll Tom The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections American journal of respiratory and critical care medicine 2017;196 (4):458-470 [PubMed]
  • van der Poll Tom, van de Veerdonk Frank L., Scicluna Brendon P., Netea Mihai G. The immunopathology of sepsis and potential therapeutic targets Nature reviews. Immunology 2017;17 (7):407-420 [PubMed]
  • Lankelma Jacqueline M. The role of the intestinal microbiota in pneumonia and sepsis 2017. 242p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Wiersinga W. J.)
  • Claushuis T. A. M., de Stoppelaar S. F., Stroo I., Roelofs J. J. T. H., Ottenhoff R., van der Poll T., van't Veer C. Thrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions Journal of thrombosis and haemostasis 2017;15 (4):744-757 [PubMed]
  • Wagemakers Alex Tick-host-Borrelia interaction: Implications for host immunity and vaccination strategies 2017. 208p. ISBN 9789462955608. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: Bins A. D., Hovius J. W. R.)
  • Scicluna Brendon P., van der Poll Tom Turning a New Page in Sepsis Molecular Diagnostics Necessitates Context-Specific Biomarkers Critical care medicine 2017;45 (4):E457 [PubMed]

2016

  • van Vught Lonneke A., Wiewel Maryse A., Klein Klouwenberg Peter M. C., Hoogendijk Arie J., Scicluna Brendon P., Ong David S. Y., Cremer Olaf L., Horn Janneke, Bonten Marc M. J., Schultz Marcus J., van der Poll Tom, de Beer FrisoM, Bos LieuweD J., Frencken JosF, Glas GerieJ, van Hooijdonk RoosmarijnT M., Huson MichaëlaA M., Schouten LauraR A., Straat Marleen, Witteveen Esther, Wieske Luuk Admission Hyperglycemia in Critically Ill Sepsis Patients: Association With Outcome and Host Response Critical care medicine 2016;44 (7):1338-1346 [PubMed]
  • Wagemakers Alex, Coumou Jeroen, Schuijt Tim J., Oei Anneke, Nijhof Ard M., van 't Veer Cornelis, van der Poll Tom, Bins Adriaan D., Hovius Joppe W. R. An Ixodes ricinus Tick Salivary Lectin Pathway Inhibitor Protects Borrelia burgdorferi sensu lato from Human Complement Vector borne and zoonotic diseases (Larchmont, N.Y.) 2016;16 (4):223-228 [PubMed]
  • Lankelma Jacqueline M., Belzer Clara, Hoogendijk Arie J., de Vos Alex F., de Vos Willem M., van der Poll Tom, Wiersinga W. Joost Antibiotic-Induced Gut Microbiota Disruption Decreases TNF-alpha Release by Mononuclear Cells in Healthy Adults Clinical and translational gastroenterology 2016;7 (8):e186 [PubMed]
  • Maude Rapeephan R., Ghose Aniruddha, Samad Rasheda, de Jong Hanna K., Fukushima Masako, Wijedoru Lalith, Hassan Mahtab Uddin, Hossain Md Amir, Karim Md Rezaul, Sayeed Abdullah Abu, van den Ende Stannie, Pal Sujat, Zahed A. S. M., Rahman Wahid, Karnain Rifat, Islam Rezina, Tran Dung Thi Ngoc, Ha Tuyen Thanh, Pham Anh Hong, Campbell James I., van Doorn H. Rogier, Maude Richard J., van der Poll Tom, Wiersinga W. Joost, Day Nicholas P. J., Baker Stephen, Dondorp Arjen M., Parry Christopher M., Faiz Md Abul A prospective study of the importance of enteric fever as a cause of non-malarial febrile illness in patients admitted to Chittagong Medical College Hospital, Bangladesh BMC infectious diseases 2016;16 (1):567 [PubMed]
  • van Vught Lonneke A., Scicluna Brendon P., Hoogendijk Arie J., Wiewel Maryse A., Klein Klouwenberg Peter M. C., Cremer Olaf L., Horn Janneke, Nürnberg Peter, Bonten Marc M. J., Schultz Marcus J., van der Poll Tom Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients Critical care (London, England) 2016;20 (1):252 [PubMed]
  • Mason Lauren M. K., Wagemakers Alex, van 't Veer Cornelis, Oei Anneke, van der Pot Wouter J., Ahmed Kalam, van der Poll Tom, Geijtenbeek Teunis B. H., Hovius Joppe W. R. Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model PLoS ONE 2016;11 (10):e0164040 [PubMed]
  • Cheng Shih-Chin, Scicluna Brendon P., Arts Rob J. W., Gresnigt Mark S., Lachmandas Ekta, Giamarellos-Bourboulis Evangelos J., Kox Matthijs, Manjeri Ganesh R., Wagenaars Jori A. L., Cremer Olaf L., Leentjens Jenneke, van der Meer Anne J., van de Veerdonk Frank L., Bonten Marc J., Schultz Marcus J., Willems Peter H. G. M., Pickkers Peter, Joosten Leo A. B., van der Poll Tom, Netea Mihai G. Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis Nature immunology 2016;17 (4):406-413 [PubMed]
  • Huson Michaëla A., Bakhshi-Raiez Ferishta, Grobusch Martin P., de Jonge Evert, de Keizer Nicolette F., van der Poll Tom Characteristics and Outcome of Patients With AIDS in Dutch ICUs Between 1997 and 2014 Critical care medicine 2016;44 (2):291-299 [PubMed]
  • Wiewel Maryse A., de Stoppelaar Sacha F., van Vught Lonneke A., Frencken Jos F., Hoogendijk Arie J., Klein Klouwenberg Peter M. C., Horn Janneke, Bonten Marc J., Zwinderman Aeilko H., Cremer Olaf L., Schultz Marcus J., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Ong David S. Y., Schouten Laura R. A., Scicluna Brendon P., Straat Marleen, Witteveen Esther, Wieske Luuk Chronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis Intensive care medicine 2016;42 (3):352-360 [PubMed]
  • Koster-Brouwer Maria E., van de Groep Kirsten, Pasma Wietze, Smeets Hugo M., Slooter Arjen J. C., de Lange Dylan W., van Dijk Diederik, van der Poll Tom, Bonten Marc J. M., Cremer Olaf L. Chronic healthcare expenditure in survivors of sepsis in the intensive care unit Intensive care medicine 2016;42 (10):1641-1642 [PubMed]
  • Kooij Katherine W., Wit Ferdinand W. N. M., Booiman Thijs, van der Valk Marc, Schim van der Loeff Maarten F., Kootstra Neeltje A., Reiss Peter, Schouten J., van Zoest R. A., Verheij E., Elsenga B. C., Prins M., Martens M., Moll S., Berkel J., Totté M., Visser G. R., May L., Kovalev S., Newsum A., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Vugt M., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., van der Velde N., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., Verbraak F. D., Demirkaya N., Nieuwkerk P. T., Langebeek N., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cigarette Smoking and Inflammation, Monocyte Activation, and Coagulation in HIV-Infected Individuals Receiving Antiretroviral Therapy, Compared With Uninfected Individuals Journal of infectious diseases 2016;214 (12):1817-1821 [PubMed]
  • van Vught Lonneke A., Scicluna Brendon P., Wiewel Maryse A., Hoogendijk Arie J., Klein Klouwenberg Peter M. C., Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Cremer Olaf L., Horn Janneke, Schultz Marcus J., Bonten Marc M. J., van der Poll Tom Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients American journal of respiratory and critical care medicine 2016;194 (11):1366-1374 [PubMed]
  • Koster-Brouwer M. E., Klein Klouwenberg P. M.C., Pasma W., Bosmans J. E., van der Poll T., Bonten M. J.M., Cremer O. L. Critical care management of severe sepsis and septic shock: A cost-analysis Netherlands journal of critical care 2016;24 (3):12-18
  • Mocroft Amanda, Lundgren Jens D., Ross Michael, Fux Christoph A., Reiss Peter, Moranne Olivier, Morlat Philippe, Monforte Antonella d'Arminio, Kirk Ole, Ryom Lene, Steering D., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Ryom L., Hatleberg C. I., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Bojesen A., Grevsen A. L., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E. Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study Lancet HIV 2016;3 (1):e23-e32 [PubMed]
  • Ong David S. Y., Spitoni Cristian, Klein Klouwenberg Peter M. C., Verduyn Lunel Frans M., Frencken Jos F., Schultz Marcus J., van der Poll Tom, Kesecioglu Jozef, Bonten Marc J. M., Cremer Olaf L. Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome Intensive care medicine 2016;42 (3):333-341 [PubMed]
  • Schouten Judith, Su Tanja, Wit Ferdinand W., Kootstra Neeltje A., Caan Matthan W. A., Geurtsen Gert J., Schmand Ben A., Stolte Ineke G., Prins Maria, Majoie Charles B., Portegies Peter, Reiss Peter, van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Gras L. A. J., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Determinants of reduced cognitive performance in HIV-1-infected middle-aged men on combination antiretroviral therapy AIDS (London, England) 2016;30 (7):1027-1038 [PubMed]
  • Shankar-Hari Manu, Phillips Gary S., Levy Mitchell L., Seymour Christopher W., Liu Vincent X., Deutschman Clifford S., Angus Derek C., Rubenfeld Gordon D., Singer Mervyn, Angus Derek, Annane Djilalli, Bauer Michael, Bellomo Rinaldo, Bernard Gordon, Chiche Jean-Daniel, Coopersmith Craig, Deutschman Cliff, Hotchkiss Richard, Levy Mitchell, Marshall John, Martin Greg, Opal Steve, Rubenfeld Gordon, Seymour Christopher, van der Poll Tom, Vincent Jean-Louis Developing a New Definition and Assessing New Clinical Criteria for Septic Shock For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA 2016;315 (8):775-787 [PubMed]
  • Coumou Jeroen Dissecting Lyme borreliosis; Clinical aspects, pathogenesis and prevention 2016. 242p. ISBN 9789462953505. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Fikrig E.; Co-supervisors: Hovius J. W. R., Narasimhan S.)
  • Anas Adam A., de Vos Alex F., Hoogendijk Arie J., van Lieshout Miriam H. P., van Heijst Jeroen W. J., Florquin Sandrine, Li Zihai, van 't Veer Cornelis, van der Poll Tom Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia Journal of pathology 2016;238 (1):74-84 [PubMed]
  • Bos Lieuwe D., Schouten Laura R., Cremer Olaf L., Ong David S. Y., Schultz Marcus J., Frencken Jos F., Bonten Marc, Klein Klouwenberg Peter M. C., Ong David, van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., Wieske Luuk, van der Poll Tom External validation of the APPS, a new and simple outcome prediction score in patients with the acute respiratory distress syndrome Annals of intensive care 2016;6 (1):89 [PubMed]
  • Op de Coul Eline L. M., van Sighem Ard, Brinkman Kees, van Benthem Birgit H., van der Ende Marchina E., Geerlings Suzanne, Reiss Peter, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Westerman A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., Hage de Looff L., Versteeg D., Pronk M. J. H., Ammerlaan H. S. M., Korsten-Vorstermans E. M. H. M., de Munnik E. S., Jansz A. R., Tjhie J., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E. Factors associated with presenting late or with advanced HIV disease in the Netherlands, 1996-2014: results from a national observational cohort BMJ open 2016;6 (1):e009688 [PubMed]
  • Scicluna Brendon P., van Vught Lonneke A., van der Poll Tom, Klein Klouwenberg Peter M. C., Cremer Olaf L. FAIM3:PLAC8 Ratio Compared with Existing Biomarkers for Diagnosis of Severe Community-acquired Pneumonia: Comparing Apples to Oranges? Reply American journal of respiratory and critical care medicine 2016;193 (1):102-103 [PubMed]
  • van der Poll Tom Future of sepsis therapies Critical care (London, England) 2016;20 (1):106 [PubMed]
  • van den Boogaard Florry E., van Gisbergen Klaas P. J. M., Vernooy Juanita H., Medema Jan P., Roelofs Joris J. T. H., van Zoelen Marieke A. D., Endeman Henrik, Biesma Douwe H., Boon Louis, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Granzyme A impairs host defense during Streptococcus pneumoniae pneumonia American journal of physiology. Lung cellular and molecular physiology 2016;311 (2):L507-L516 [PubMed]
  • Wensink Annette C., Wiewel Maryse A., Jongeneel Lieneke H., Boes Marianne, van der Poll Tom, Hack C. Erik, Bovenschen Niels Granzyme M and K release in human experimental endotoxemia Immunobiology 2016;221 (7):773-777 [PubMed]
  • García-Laorden M. Isabel, Stroo Ingrid, Blok Dana C., Florquin Sandrine, Medema Jan Paul, de Vos Alex F., van der Poll Tom Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia Journal of innate immunity 2016;8 (3):258-268 [PubMed]
  • Lin Cong, von der Thüsen Jan, Isermann Berend, Weiler Hartmut, van der Poll Tom, Borensztajn Keren, Spek Chris A. High endogenous activated protein C levels attenuates bleomycin-induced pulmonary fibrosis Journal of cellular and molecular medicine 2016;20 (11):2029-2035 [PubMed]
  • Demirkaya Nazli, Wit Ferdinand W. N. M., van den Berg Thomas J. T. P., Kooij Katherine W., Prins Maria, Schlingemann Reinier O., Abramoff Michael D., Reiss Peter, Verbraak Frank D., van der Valk M., Schouten J. [=Judith], van Zoest R. A., Elsenga B. C., Martens M., Moll S., Berkel J., Totté M., Visser G. R., Kovalev S., Kootstra N. A., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study Investigative ophthalmology & visual science 2016;57 (3):1388-1397 [PubMed]
  • Kooij Katherine W., Wit Ferdinand W. N. M., Schouten Judith, van der Valk Marc, Godfried Mieke H., Stolte Ineke G., Prins Maria, Falutz Julian, Reiss Peter, van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Hillebregt M. M. J., Gras L. A. J., Ruijs Y. M. C., Benschop D. P., Kootstra N. A., Harskamp-Holwerda A. M., Maurer I., Ruiz M. M. Mangas, Girigorie A. F., van Leeuwen E., Janssen F. R., Heidenrijk M., Schrijver J. H. N., Zikkenheiner W., Wezel M., Jansen-Kok C. S. M., Geerlings S. E., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J. HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls AIDS (London, England) 2016;30 (2):241-250 [PubMed]
  • Weehuizen Tassili A. F. Host-pathogen interactions during melioidosis. When the bug meets its host 2016. 303p. ISBN 9789461698865. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Wiersinga W. J.)
  • Zhang Haibo, Li Yimin, van der Poll Tom Immune Modulation in Sepsis: Is There a Place for Progranulin? American journal of respiratory and critical care medicine 2016;194 (10):1179-1180 [PubMed]
  • Huson Michaëla A. M., Kalkman Rachel, Hoogendijk Arie J., Alabi Abraham S., van 't Veer Cornelis, Grobusch Martin P., Meijers Joost C. M., van der Poll Tom Impact of HIV infection on the haemostatic response during sepsis and malaria British journal of haematology 2016;173 (6):918-926 [PubMed]
  • Wiewel Maryse A., Huson Michaëla A., van Vught Lonneke A., Hoogendijk Arie J., Klein Klouwenberg Peter M. C., Horn Janneke, Lutter René, Cremer Olaf L., Schultz Marcus J., Bonten Marc J., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Frencken Jos F., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Ong David S. Y., Schouten Laura R. A., Scicluna Brendon P., Straat Marleen, Witteveen Esther, Wieske Luuk Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study Critical care (London, England) 2016;20 (1):322 [PubMed]
  • van Vught Lonneke A., Klein Klouwenberg Peter M. C., Spitoni Cristian, Scicluna Brendon P., Wiewel Maryse A., Horn Janneke, Schultz Marcus J., Nürnberg Peter, Bonten Marc J. M., Cremer Olaf L., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Frencken Jos F., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Hoogendijk Arie J., Huson Mischa A., Ong David S. Y., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis JAMA 2016;315 (14):1469-1479 [PubMed]
  • Anas Adam A., van Lieshout Miriam H. P., Claushuis Theodora A. M., de Vos Alex F., Florquin Sandrine, de Boer Onno J., Hou Baidong, van't Veer Cornelis, van der Poll Tom Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism American journal of physiology. Lung cellular and molecular physiology 2016;311 (2):L219-L228 [PubMed]
  • Geldhoff Madelijn Pathophysiology of pneumococcal meningitis 2016. 215p. ISBN 9789463320627. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van de Beek D., van der Poll T.; Co-supervisor: Brouwer M. C.)
  • Stolk Roeland F., van der Poll Tom, Angus Derek C., van der Hoeven Johannes G., Pickkers Peter, Kox Matthijs Potentially Inadvertent Immunomodulation: Norepinephrine Use in Sepsis American journal of respiratory and critical care medicine 2016;194 (5):550-558 [PubMed]
  • Prins J. M., van der Poll T. Procalcitoninebepaling nuttig bij luchtweginfecties? Nederlands tijdschrift voor geneeskunde 2016;160:D957 [PubMed]
  • Sneeboer Marlous M. S., Majoor Christof J., de Kievit Anne, Meijers Joost C. M., van der Poll Tom, Kamphuisen Pieter W., Bel Elisabeth H. Prothrombotic state in patients with severe and prednisolone-dependent asthma Journal of allergy and clinical immunology 2016;137 (6):1727-1732 [PubMed]
  • Achouiti Ahmed, de Vos Alex F., van 't Veer Cornelis, Florquin Sandrine, Tanck Michael W., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom, van Zoelen Marieke A. D. Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia PLoS ONE 2016;11 (1):e0141000 [PubMed]
  • Wiewel Maryse A., Harmon Matthew B., van Vught Lonneke A., Scicluna Brendon P., Hoogendijk Arie J., Horn Janneke, Zwinderman Aeilko H., Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom, Juffermans Nicole P., Wiersinga W. Joost Risk factors, host response and outcome of hypothermic sepsis Critical care (London, England) 2016;20 (1):328 [PubMed]
  • van Vught Lonneke A., Klein Klouwenberg Peter M. C., van der Poll Tom Secondary Infection in Patients With Sepsis Reply JAMA 2016;316 (7):772 [PubMed]
  • Huson Michaëla A. M. Sepsis in HIV-infected patients; epidemiology and host response 2016. 275p. ISBN 9789461698544. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Grobusch M. P.)
  • van Vught Lonneke A. Sepsis in the intensive care unit: epidemiology, outcome and host response 2016. 367p. ISBN 9789462954625. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Scicluna B. P.)
  • Kissoon Niranjan, Daniels Ron, van der Poll Tom, Finfer Simon, Reinhart Konrad Sepsis-The Final Common Pathway to Death From Multiple Organ Failure in Infection Critical care medicine 2016;44 (6):e446 [PubMed]
  • Achhra A. C., Mocroft A., Reiss P., Sabin C., Ryom L., de Wit S., Smith C. J., d'Arminio Monforte A., Phillips A., Weber R., Lundgren J., Law M. G., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Hatleberg C. I., Sabin C. A., Kamara D., Smith C., Bojesen A., Nielsen J., Raben D., Lundgren J. D., Salbøl Brandt R., Rickenbach M., Fanti I., Krum E., Hillebregt M., Geffard S., Sundström A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Short-term weight gain after antiretroviral therapy initiation and subsequent risk of cardiovascular disease and diabetes: the D:A:D study HIV medicine 2016;17 (4):255-268 [PubMed]
  • Cobos Jiménez Viviana, Wit Ferdinand W. N. M., Joerink Maaike, Maurer Irma, Harskamp Agnes M., Schouten Judith, Prins Maria, van Leeuwen Ester M. M., Booiman Thijs, Deeks Steven G., Reiss Peter, Kootstra Neeltje A., van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Martens M., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., Nellen F. J. B., van der Meer J. T. M., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment Journal of infectious diseases 2016;214 (2):216-225 [PubMed]
  • Schuijt Tim J., Lankelma Jacqueline M., Scicluna Brendon P., de Sousa E Melo Felipe, Roelofs Joris J. T. H., de Boer J. Daan, Hoogendijk Arjan J., de Beer Regina, de Vos Alex, Belzer Clara, de Vos Willem M., van der Poll Tom, Wiersinga W. Joost The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia Gut 2016;65 (4):575-583 [PubMed]
  • Huson Michaëla A. M., Scicluna Brendon P., van Vught Lonneke A., Wiewel Maryse A., Hoogendijk Arie J., Cremer Olaf L., Bonten Marc J. M., Schultz Marcus J., Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Grobusch Martin P., van der Poll Tom The Impact of HIV Co-Infection on the Genomic Response to Sepsis PLoS ONE 2016;11 (2):e0148955 [PubMed]
  • Huson Michaëla A. M., Hoogendijk Arie J., de Vos Alex F., Grobusch Martin P., van der Poll Tom The impact of HIV infection on blood leukocyte responsiveness to bacterial stimulation in asymptomatic patients and patients with bloodstream infection Journal of the International AIDS Society 2016;19 (1):20759 [PubMed]
  • Majoor C. J., Sneeboer M. M. S., de Kievit A., Meijers J. C. M., van der Poll T., Lutter R., Bel E. H., Kamphuisen P. W. The influence of corticosteroids on hemostasis in healthy subjects Journal of thrombosis and haemostasis 2016;14 (4):716-723 [PubMed]
  • Singer Mervyn, Deutschman Clifford S., Seymour Christopher Warren, Shankar-Hari Manu, Annane Djillali, Bauer Michael, Bellomo Rinaldo, Bernard Gordon R., Chiche Jean-Daniel, Coopersmith Craig M., Hotchkiss Richard S., Levy Mitchell M., Marshall John C., Martin Greg S., Opal Steven M., Rubenfeld Gordon D., van der Poll Tom, Vincent Jean-Louis, Angus Derek C. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA 2016;315 (8):801-810 [PubMed]
  • Borgdorff Hanneke The vaginal microbiome: Associations with sexually transmitted infections and the mucosal immune response 2016. 226p. ISBN 9789461698193. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van de Wijgert J. H. H. M., van der Poll T.; Co-supervisor: Geerlings S. E.)
  • Claushuis Theodora A. M., van Vught Lonneke A., Scicluna Brendon P., Wiewel Maryse A., Klein Klouwenberg Peter M. C., Hoogendijk Arie J., Ong David S. Y., Cremer Olaf L., Horn Janneke, Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Zwinderman Aeilko H., Bonten Marc J., Schultz Marcus J., van der Poll Tom Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients Blood 2016;127 (24):3062-3072 [PubMed]
  • van der Meer Anne Jan, Achouiti Achmed, van der Ende Arie, Soussan Aicha A., Florquin Sandrine, de Vos Alex, Zeerleder Sacha S., van der Poll Tom Toll-like receptor 9 enhances bacterial clearance and limits lung consolidation in murine pneumonia caused by methicillin resistant Staphylococcus aureus Molecular medicine (Cambridge, Mass.) 2016;22:292-299 [PubMed]
  • de Stoppelaar Sacha F., Claushuis Theodora A. M., Schaap Marianne C. L., Hou Baidong, van der Poll Tom, Nieuwland Rienk, van 't Veer Cornelis Toll-Like Receptor Signalling Is Not Involved in Platelet Response to Streptococcus pneumoniae In Vitro or In Vivo PLoS ONE 2016;11 (6):e0156977 [PubMed]
  • Engele Leo J., Straat Marleen, van Rooijen Ingeborg H. M., de Vooght Karen M. K., Cremer Olaf L., Schultz Marcus J., Bos Lieuwe D. J., Juffermans Nicole P., de Beer Friso M., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., Wieske Luuk, van der Poll Tom, Bonten Marc J. M., Frencken Jos F., Klein Klouwenberg Peter M. C., Ong DavidS Y. Transfusion of platelets, but not of red blood cells, is independently associated with nosocomial infections in the critically ill Annals of intensive care 2016;6 (1):67 [PubMed]
  • Weehuizen Tassili A. F., Hommes Tijmen J., Lankelma Jacqueline M., de Jong Hanna K., Roelofs Joris J. T. H., de Vos Alex F., Colonna Marco, van der Poll Tom, Wiersinga W. Joost Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis PLoS neglected tropical diseases 2016;10 (6):e0004747 [PubMed]
  • Wagemakers Alex, Koetsveld Joris, Narasimhan Sukanya, Wickel Melvin, Deponte Kathleen, Bleijlevens Boris, Jahfari Seta, Sprong Hein, Karan Lyudmila S., Sarksyan Denis S., van der Poll Tom, Bockenstedt Linda K., Bins Adriaan D., Platonov Alexander E., Fikrig Erol, Hovius Joppe W. Variable Major Proteins as Targets for Specific Antibodies against Borrelia miyamotoi Journal of immunology (Baltimore, Md. 2016;196 (10):4185-4195 [PubMed]
  • Rokx C., Gras L., van de Vijver Damc, Verbon A., Rijnders Bja, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Lowe S., Oude Lashof A., Posthouwer D., Pronk M. J. H., Ammerlaan H. S. M., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., van Gorp E. C. M., van der Feltz M., Driessen G. J. A., van Rossum A. M. C., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Bouwhuis J. W., Soetekouw R., ten Kate R. W., Kroon F. P., van Dissel J. T., Arend S. M., de Boer M. G. J., Jolink H., Vollaard A. M. Virological responses to lamivudine or emtricitabine when combined with tenofovir and a protease inhibitor in treatment-naïve HIV-1-infected patients in the Dutch AIDS Therapy Evaluation in the Netherlands (ATHENA) cohort HIV medicine 2016;17 (8):571-580 [PubMed]

2015

  • de Boer J. Daan, Berger Marieke, Majoor Christof J., Kager Liesbeth M., Meijers Joost C. M., Terpstra Sanne, Nieuwland Rienk, Boing Anita N., Lutter René, Wouters Diana, van Mierlo Gerard J., Zeerleder Sacha S., Bel Elisabeth H., van't Veer Cornelis, de Vos Alex F., van der Zee Jaring S., van der Poll Tom Activated protein C inhibits neutrophil migration in allergic asthma: a randomised trial European respiratory journal 2015;46 (6):1636-1644 [PubMed]
  • Scicluna Brendon P., Klein Klouwenberg Peter M. C., van Vught Lonneke A., Wiewel Maryse A., Ong David S. Y., Zwinderman Aeilko H., Franitza Marek, Toliat Mohammad R., Nürnberg Peter, Hoogendijk Arie J., Horn Janneke, Cremer Olaf L., Schultz Marcus J., Bonten Marc J., van der Poll Tom A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission American journal of respiratory and critical care medicine 2015;192 (7):826-835 [PubMed]
  • McHugh Leo, Seldon Therese A., Brandon Roslyn A., Kirk James T., Rapisarda Antony, Sutherland Allison J., Presneill Jeffrey J., Venter Deon J., Lipman Jeffrey, Thomas Mervyn R., Klein Klouwenberg Peter M. C., van Vught Lonneke, Scicluna Brendon, Bonten Marc, Cremer Olaf L., Schultz Marcus J., van der Poll Tom, Yager Thomas D., Brandon Richard B. A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts PLoS medicine 2015;12 (12):e1001916 [PubMed]
  • Cain Lauren E., Phillips Andrew, Olson Ashley, Sabin Caroline, Jose Sophie, Justice Amy, Tate Janet, Logan Roger, Robins James M., Sterne Jonathan A. C., van Sighem Ard, Reiss Peter, Young James, Fehr Jan, Touloumi Giota, Paparizos Vasilis, Esteve Anna, Casabona Jordi, Monge Susana, Moreno Santiago, Seng Rémonie, Meyer Laurence, Pérez-Hoyos Santiago, Muga Roberto, Dabis François, Vandenhende Marie-Anne, Abgrall Sophie, Costagliola Dominique, Hernán Miguel A., Ainsworth Jonathan, Anderson Jane, Babiker Abdel, Delpech Valerie, Gras L. A. J., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J. Boosted Lopinavir- Versus Boosted Atazanavir-Containing Regimens and Immunologic, Virologic, and Clinical Outcomes: A Prospective Study of HIV-Infected Individuals in High-Income Countries Clinical infectious diseases 2015;60 (8):1262-1268 [PubMed]
  • Mason Lauren M. K., Herkes Eduard A., Krupna-Gaylord Michelle A., Oei Anneke, van der Poll Tom, Wormser Gary P., Schwartz Ira, Petzke Mary M., Hovius Joppe W. R. Borrelia burgdorferi clinical isolates induce human innate immune responses that are not dependent on genotype Immunobiology 2015;220 (10):1141-1150 [PubMed]
  • Bruyand Mathias, Ryom Lene, Shepherd Leah, Fatkenheuer Gerd, Grulich Andrew, Reiss Peter, de Wit Stéphane, D Arminio Monforte Antonella, Furrer Hansjakob, Pradier Christian, Lundgren Jens, Sabin Caroline, Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Ryom L., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Mansfeld M., Nielsen J., Raben D., Lundgren J. D., Salbøl Brandt R., Rickenbach M., Fanti I., Krum E., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Cancer risk and use of protease inhibitor or nonnucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy: the D: A: D study JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2015;68 (5):568-577 [PubMed]
  • van Lieshout Miriam Hanneke Petra Cell-specific pattern recognition receptor signaling in antibacterial defense 2015. 264p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., de Vos A. F.)
  • Gras Luuk, de Wolf Frank, Smit Colette, Prins Maria, van der Meer Jan T. M., Vanhommerig Joost W., Zwinderman Aeilko H., Schinkel Janke, Geskus Ronald B., Kuijpers T. W., Scherpbier H. J., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Lowe S., Oude Lashof A., Posthouwer D., Pronk M. J. H., Ammerlaan H. S. M., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., Verbon A., Rijnders B. J. A., van Gorp E. C. M., van der Feltz M., Driessen G. J. A., van Rossum A. M. C., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld H. P., Bouwhuis J. W., Soetekouw R., ten Kate R. W., Kroon F. P., van Dissel J. T., Arend S. M. Changes in HIV RNA and CD4 cell count after acute HCV infection in chronically HIV-infected individuals JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2015;68 (5):536-542 [PubMed]
  • Levi Marcel, Poll Tom van der Coagulation in patients with severe sepsis Seminars in thrombosis and hemostasis 2015;41 (1):9-15 [PubMed]
  • Lodi Sara, Phillips Andrew, Logan Roger, Olson Ashley, Costagliola Dominique, Abgrall Sophie, van Sighem Ard, Reiss Peter, Miró José M., Ferrer Elena, Justice Amy, Gandhi Neel, Bucher Heiner C., Furrer Hansjakob, Moreno Santiago, Monge Susana, Touloumi Giota, Pantazis Nikos, Sterne Jonathan, Young Jessica G., Meyer Laurence, Seng Rémonie, Dabis Francois, Vandehende Marie-Anne, Pérez-Hoyos Santiago, Jarrín Inma, Jose Sophie, Sabin Caroline, Hernán Miguel A., Ainsworth J., Anderson J., Babiker A., Delpech V., Prins J. M., Kuijpers T. W., Godfried M. H., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Gras L. A. J., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M. Comparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study Lancet HIV 2015;2 (8):e335-e343 [PubMed]
  • Scicluna Brendon P., Klein Klouwenberg Peter M. C., van der Poll Tom Comprehensive Validation of the FAIM3:PLAC8 Ratio in Time-matched Public Gene Expression Data Reply American journal of respiratory and critical care medicine 2015;192 (10):1261-1262 [PubMed]
  • Mocroft Amanda, Lundgren Jens D., Ross Michael, Law Matthew, Reiss Peter, Kirk Ole, Smith Colette, Wentworth Deborah, Neuhaus Jacqueline, Fux Christoph A., Moranne Olivier, Morlat Phillipe, Johnson Margaret A., Ryom Lene, Lundgren J. D., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Sabin C. A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E., Grijsen M., Lange J., van der Horst C., Frank M. Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study PLoS medicine 2015;12 (3):e1001809 [PubMed]
  • Schoffelen Annelot F., Smit Colette, van Lelyveld Steven F. L., Vogt Liffert, Bauer Martijn P., Reiss Peter, Hoepelman Andy I. M., Barth Roos E., Prins J. M., Kuijpsers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Westerman A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., Sabbe L., Goudswaard J., Pronk M. J. H., Ammerlaan H. S. M., Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E., Gras L. A. J. Diminished impact of ethnicity as a risk factor for chronic kidney disease in the current HIV treatment era Journal of infectious diseases 2015;212 (2):264-274 [PubMed]
  • Bezemer Daniela, Cori Anne, Ratmann Oliver, van Sighem Ard, Hermanides Hillegonda S., Dutilh Bas E., Gras Luuk, Rodrigues Faria Nuno, van den Hengel Rob, Duits Ashley J., Reiss Peter, de Wolf Frank, Fraser Christophe, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., Wiersinga W. J., van der Valk M., Goorhuis A., Hovius J. W., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J., Westerman A. M., Jurriaans S., Back N. K. T., Zaaijer H. L., Berkhout B., Cornelissen M. T. E., Schinkel C. J., Thomas X. V., van den Berge M., Stegeman A., Baas S., de Looff L. Hage, Stelma F. F., Langebeek N., Vandenbroucke-Grauls C. M. J. E. Dispersion of the HIV-1 Epidemic in Men Who Have Sex with Men in the Netherlands: A Combined Mathematical Model and Phylogenetic Analysis PLoS medicine 2015;12 (11):e1001898; discussion e1001898 [PubMed]
  • de Boer Johannes D., Berkhout Lea C., de Stoppelaar Sacha F., Yang Jack, Ottenhoff Roelof, Meijers Joost C. M., Roelofs Joris J. T. H., van't Veer Cornelis, van der Poll Tom Effect of the oral thrombin inhibitor dabigatran on allergic lung inflammation induced by repeated house dust mite administration in mice American journal of physiology. Lung cellular and molecular physiology 2015;309 (8):L768-L775 [PubMed]
  • Achouiti Ahmed Endogenous danger signals in infectious diseases 2015. 272p. ISBN 9789461697240. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., de Vos A. F.)
  • van den Boogaard Florry E., van 't Veer Cornelis, Roelofs Joris J. T. H., Meijers Joost C. M., Schultz Marcus J., Broze George J., van der Poll Tom Endogenous tissue factor pathway inhibitor has a limited effect on host defence in murine pneumococcal pneumonia Thrombosis and haemostasis 2015;114 (1):115-122 [PubMed]
  • Opal S. M., van der Poll T. Endothelial barrier dysfunction in septic shock Journal of internal medicine 2015;277 (3):277-293 [PubMed]
  • Ong David S. Y., Bonten Marc J. M., Safdari Khatera, Spitoni Cristian, Frencken Jos F., Witteveen Esther, Horn Janneke, Klein Klouwenberg Peter M. C., Cremer Olaf L., de Beer Friso M., Bos Lieuwe D. J., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A., Glas Gerie J., Wieske Luuk, Schultz Marcus J., van der Poll Tom Epidemiology, Management, and Risk-Adjusted Mortality of ICU-Acquired Enterococcal Bacteremia Clinical infectious diseases 2015;61 (9):1413-1420 [PubMed]
  • de Jong Hanna K., Achouiti Ahmed, Koh Gavin C. K. W., Parry Christopher M., Baker Stephen, Faiz Mohammed Abul, van Dissel Jaap T., Vollaard Albert M., van Leeuwen Ester M. M., Roelofs Joris J. T. H., de Vos Alex F., Roth Johannes, van der Poll Tom, Vogl Thomas, Wiersinga Willem Joost Expression and function of S100A8/A9 (calprotectin) in human typhoid fever and the murine Salmonella model PLoS neglected tropical diseases 2015;9 (4):e0003663 [PubMed]
  • Blok Dana C., Kager Liesbeth M., Hoogendijk Arie J., Lede Ivar O., Rahman Wahid, Afroz Rumana, Bresser Paul, van der Zee Jaring S., Ghose Aniruddha, Visser Caroline E., de Jong Menno D., Zahed Abu Shahed Md, Husain Md Anwar, Alam Khan Mashrequl, Barua Pravat Chandra, Hassan Mahtabuddin, Hossain Ahmed, Tayab Md Abu, Lutter Rene, Day Nick, Dondorp Arjen M., de Vos Alex F., van 't Veer Cornelis, van der Poll Tom Expression of inhibitory regulators of innate immunity in patients with active tuberculosis BMC infectious diseases 2015;15 (1):98 [PubMed]
  • Bos Lieuwe D., Cremer Olaf L., Ong David S. Y., Caser Eliana B., Barbas Carmen S. V., Villar Jesus, Kacmarek Robert M., Schultz Marcus J., Frencken Jos F., Bonten Marc, Klein Klouwenberg Peter M. C., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., Wieske Luuk, van der Poll Tom External validation confirms the legitimacy of a new clinical classification of ARDS for predicting outcome Intensive care medicine 2015;41 (11):2004-2005 [PubMed]
  • Wildhagen Karin C. A. A., Wiewel Maryse A., Schultz Marcus J., Horn Janneke, Schrijver Roy, Reutelingsperger Chris P. M., van der Poll Tom, Nicolaes Gerry A. F. Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients Thrombosis research 2015;136 (3):542-547 [PubMed]
  • van den Boogaard Florry E., Hofstra Jorrit J., van 't Veer Cornelis, Levi Marcel M., Roelofs Joris J. T. H., van der Poll Tom, Schultz Marcus J. Feasibility and Safety of Local Treatment with Recombinant Human Tissue Factor Pathway Inhibitor in a Rat Model of Streptococcus pneumoniae Pneumonia PLoS ONE 2015;10 (5):e0127261 [PubMed]
  • Huson Michaëla A. M., Wouters Diana, van Mierlo Gerard, Grobusch Martin P., Zeerleder Sacha S., van der Poll Tom HIV Coinfection Enhances Complement Activation During Sepsis Journal of infectious diseases 2015;212 (3):474-483 [PubMed]
  • Huson Michaëla A. M., Zeerleder Sacha S., van Mierlo Gerard, Wouters Diana, Grobusch Martin P., van der Poll Tom HIV infection is associated with elevated nucleosomes in asymptomatic patients and during sepsis or malaria Journal of infection 2015;71 (2):266-269 [PubMed]
  • de Jong Hanna Katrien Host-pathogen interactions in typhoid fever 2015. 269p. ISBN 9789462951419. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: Parry C. M., Wiersinga W. J.)
  • Garcia-Laorden M. Isabel, Blok Dana C., Kager Liesbeth M., Hoogendijk Arie J., van Mierlo Gerard J., Lede Ivar O., Rahman Wahid, Afroz Rumana, Ghose Aniruddha, Visser Caroline E., Md Zahed Abu Shahed, Husain Md Anwar, Alam Khan Mashrequl, Chandra Barua Pravat, Hassan Mahtabuddin, Hossain Ahmed, Tayab Md Abu, Day Nick, Dondorp Arjen M., de Vos Alex F., van der Poll Tom Increased intra- and extracellular granzyme expression in patients with tuberculosis Tuberculosis (Edinburgh, Scotland) 2015;95 (5):575-580 [PubMed]
  • Lin Cong, von der Thüsen Jan, van der Poll Tom, Borensztajn Keren, Spek C. Arnold Increased Mortality during Bleomycin-induced Pulmonary Fibrosis due to Low Endogenous Activated Protein C Levels American journal of respiratory and critical care medicine 2015;192 (10):1257-1259 [PubMed]
  • Paris Daniel H., Stephan Femke, Bulder Ingrid, Wouters Diana, van der Poll Tom, Newton Paul N., Day Nicholas P. J., Zeerleder Sacha Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos PLoS neglected tropical diseases 2015;9 (8):e0003990 [PubMed]
  • Rokx Casper, Fibriani Azzania, van de Vijver David A. M. C., Verbon Annelies, Schutten Martin, Gras Luuk, Rijnders Bart J. A., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Lowe S., Oude Lashof A., Posthouwer D., Pronk J. H., Ammerlaan H. S. M., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., Verbon A., Rijnders B. J. A., van Gorp E. C. M., van der Feltz M., Driessen G. J. A., van Rossum A. M. C., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Bouwhuis J. W., Soetekouw R., ten Kate R. W., Kroon F. P., van Dissel J. T. Increased Virological Failure in Naive HIV-1-Infected Patients Taking Lamivudine Compared With Emtricitabine in Combination With Tenofovir and Efavirenz or Nevirapine in the Dutch Nationwide ATHENA Cohort Clinical infectious diseases 2015;60 (1):143-153 [PubMed]
  • Boshuizen Margit, Leopold Jan Hendrik, Zakharkina Tetyana, Knobel Hugo H., Weda Hans, Nijsen Tamara M. E., Vink Teunis J., Sterk Peter J., Schultz Marcus J., Bos Lieuwe D. J., Cremer Olaf L., Klein Klouwenberg Peter M. C., Ong David S. Y., Frencken Jos F., Bonten Marc J. M., Horn Janneke, Juffermans Nicole, van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., de Beer Friso M., Wieske Luuk, van der Poll Tom Levels of cytokines in broncho-alveolar lavage fluid, but not in plasma, are associated with levels of markers of lipid peroxidation in breath of ventilated ICU patients Journal of breath research 2015;9 (3):036010 [PubMed]
  • Klein Klouwenberg Peter M. C., Cremer Olaf L., van Vught Lonneke A., Ong David S. Y., Frencken Jos F., Schultz Marcus J., Bonten Marc J., van der Poll Tom Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study Critical care (London, England) 2015;19 (1):319 [PubMed]
  • Berger M., de Boer J. D., Bresser P., van der Poll T., Lutter R., Sterk P. J., van der Zee J. S. Lipopolysaccharide amplifies eosinophilic inflammation after segmental challenge with house dust mite in asthmatics Allergy 2015;70 (3):257-264 [PubMed]
  • Kuemmerle-Deschner J., Hoffman H., Hawkins P. N., van der Poll T., Walker U. A., Speziale A., Tilson H. H. Long-term safety and efficacy of Canakinumab in cryopyrin-associated periodic syndrome (CAPS) patients: Results from beta-confident registry Pediatric rheumatology online journal 2015;13 (1)
  • Lombardo Eleuterio, van der Poll Tom, DelaRosa Olga, Dalemans Wilfried Mesenchymal stem cells as a therapeutic tool to treat sepsis World journal of stem cells 2015;7 (2):368-379 [PubMed]
  • Scicluna Brendon P., van Lieshout Miriam H., Blok Dana C., Florquin Sandrine, van der Poll Tom Modular Transcriptional Networks of the Host Pulmonary Response during Early and Late Pneumococcal Pneumonia Molecular medicine (Cambridge, Mass.) 2015;21 (1):430-441 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, van der Meer Anne J., Stroo Ingrid, Florquin Sandrine, de Boer Onno J., Roth Johannes, Zeerleder Sacha, van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia European respiratory journal 2015;46 (2):464-473 [PubMed]
  • Lin Cong, von der Thüsen Jan, Daalhuisen Joost, ten Brink Marieke, Crestani Bruno, van der Poll Tom, Borensztajn Keren, Spek C. Arnold Pharmacological Targeting of Protease-Activated Receptor 2 Affords Protection from Bleomycin-Induced Pulmonary Fibrosis Molecular medicine (Cambridge, Mass.) 2015;21 (1):576-583 [PubMed]
  • Hoogendijk Arie J., Wiewel Maryse A., van Vught Lonneke A., Scicluna Brendon P., Belkasim-Bohoudi Hakima, Horn Janneke, Zwinderman Aeilko H., Klein Klouwenberg Peter M. C., Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom, de Beer Friso M., Bos Lieuwe D. J., Frencken Jos F., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Ong David S. Y., Schouten Laura R. A., Straat Marleen, Witteveen Esther Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients Critical care (London, England) 2015;19 (1):412 [PubMed]
  • Geboers Diederik G. P. J., de Beer Friso M., Tuip-de Boer Anita M., van der Poll Tom, Horn Janneke, Cremer Olaf L., Bonten Marc J. M., Ong David S. Y., Schultz Marcus J., Bos Lieuwe D. J. Plasma suPAR as a prognostic biological marker for ICU mortality in ARDS patients Intensive care medicine 2015;41 (7):1281-1290 [PubMed]
  • de Stoppelaar S. F., van't Veer C., Roelofs J. J. T. H., Claushuis T. A. M., de Boer O. J., Tanck M. W. T., Hoogendijk A. J., van der Poll T. Platelet and endothelial cell P-selectin are required for host defense against Klebsiella pneumoniae-induced pneumosepsis Journal of thrombosis and haemostasis 2015;13 (6):1128-1138 [PubMed]
  • de Stoppelaar Sacha Francien Platelets: versatile effector cells in pneumonia and sepsis 2015. 201p. ISBN 9789462951181. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: van 't Veer C.)
  • Lin Cong Potential novel targets: Protease-activated receptors in idiopathic pulmonary fibrosis 2015. 147p. ISBN 9789462991293. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: Spek C. A., Borensztajn K.)
  • Lin Cong, Rezaee Farhad, Waasdorp Maaike, Shi Kun, van der Poll Tom, Borensztajn Keren, Spek C. Arnold Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis Oncotarget 2015;6 (34):35304-35314 [PubMed]
  • Lin Cong, von der Thüsen Jan, Daalhuisen Joost, ten Brink Marieke, Crestani Bruno, van der Poll Tom, Borensztajn Keren, Spek C. Arnold Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis Journal of cellular and molecular medicine 2015;19 (6):1346-1356 [PubMed]
  • Kager Liesbeth M., Blok Dana C., Lede Ivar O., Rahman Wahid, Afroz Rumana, Bresser Paul, van der Zee Jaring S., Ghose Aniruddha, Visser Caroline E., de Jong Menno D., Tanck Michael W., Zahed Abu Shahed M., Alam Khan Mashrequl, Hassan Mahtabuddin, Hossain Ahmed, Lutter Rene, Veer Cornelis Van't, Dondorp Arjen M., Meijers Joost C. M., van der Poll Tom Pulmonary tuberculosis induces a systemic hypercoagulable state Journal of infection 2015;70 (4):324-334 [PubMed]
  • van Vught Lonneke A., Wiewel Maryse A., Hoogendijk Arie J., Scicluna Brendon P., Belkasim-Bohoudi Hakima, Horn Janneke, Schultz Marcus J., van der Poll Tom Reduced Responsiveness of Blood Leukocytes to Lipopolysaccharide Does not Predict Nosocomial Infections in Critically Ill Patients Shock (Augusta, Ga.) 2015;44 (2):110-114 [PubMed]
  • Zhang S., van sighem A., Kesselring A., Gras L., Prins J. M., Hassink E., Kauffmann R., Richter C., de Wolf F., Reiss P., Bezemer D. O., Gras L. A. J., Kesselring A. M., van Sighem A. I., Smit C., Zaheri S., van Twillert G., Kortmann W., Cohen Stuart J. W. T., Diederen B. M. W., Branger J., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R., Brinkman K., Blok W. L., Frissen P. H. J., Schouten W. E. M., van den Berk G. E. L., Veenstra J., Lettinga K. D., Mulder J. W., Vrouenraets S. M. E., Lauw F. N., van Goyen Jan, van Eeden A. Risk of non-AIDS-defining events among HIV-infected patients not yet on antiretroviral therapy HIV medicine 2015;16 (5):265-272 [PubMed]
  • Hommes Tijmen J., van Lieshout Miriam H., van 't Veer Cornelis, Florquin Sandrine, Bootsma Hester J., Hermans Peter W., de Vos Alex F., van der Poll Tom Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia PLoS ONE 2015;10 (12):e0145138 [PubMed]
  • Hommes Tijmen J., Dessing Mark C., Veer Cornelis van 't, Florquin Sandrine, Colonna Marco, de Vos Alex F., van der Poll Tom Role of Triggering Receptor Expressed on Myeloid Cells-1/3 in Klebsiella-Derived Pneumosepsis American journal of respiratory cell and molecular biology 2015;53 (5):647-655 [PubMed]
  • Cohen Jonathan, Vincent Jean-Louis, Adhikari Neill K. J., Machado Flavia R., Angus Derek C., Calandra Thierry, Jaton Katia, Giulieri Stefano, Delaloye Julie, Opal Steven, Tracey Kevin, van der Poll Tom, Pelfrene Eric Sepsis: a roadmap for future research Lancet infectious diseases 2015;15 (5):581-614 [PubMed]
  • Hoogendijk Arie J., Blok Dana C., Garcia Laorden M. Isabel, Kager Liesbeth M., Lede Ivar O., Rahman Wahid, Afroz Rumana, Bresser Paul, van der Zee Jaring S., Ghose Aniruddha, Visser Caroline E., de Jong Menno D., Zahed Abu Shahed Md, Husain Md Anwar, Alam Khan Mashrequl, Barua Pravat Chandra, Hassan Mahtabuddin, Hossain Ahmed, Tayab Md Abu, Lutter Rene, Day Nick, Dondorp Arjen M., van't Veer Cornelis, de Vos Alex F., van der Poll Tom Soluble and cell-associated triggering receptor expressed on myeloid cells-1 and -2 in patients with pulmonary tuberculosis Journal of infection 2015;71 (6):706-709 [PubMed]
  • Dessing Mark C., Tammaro Alessandra, Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., Claessen Nike, van Eijk Marco, van der Poll Tom, Vogl Thomas, Roth Johannes, Florquin Sandrine, Leemans Jaklien C. The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion Kidney international 2015;87 (1):85-94 [PubMed]
  • Schouten Marcel, van 't Veer Cornelis, Poulussen Nadia, Meijers Joost C. M., Levi Marcel, Esmon Charles T., van der Poll Tom The cytoprotective effects of endogenous activated protein C reduce activation of coagulation during murine pneumococcal pneumonia and sepsis Thrombosis research 2015;135 (3):537-543 [PubMed]
  • Maude Rapeephan R., de Jong Hanna K., Wijedoru Lalith, Fukushima Masako, Ghose Aniruddha, Samad Rasheda, Hossain Mohammed Amir, Karim Mohammed Rezaul, Faiz Mohammed Abul, Parry Christopher M., Sayeed Abdullah Abu, Hasan Uddin, Pan-Ngum Wirichada, van der Vaart Thomas W., Dutta Asok Kumar, Mahmud Nasir Uddin, Hero Murad, Iqbal Nafiz, Chaudhury Zabeen, Nga Tran Vu Thieu, Duy Pham Thanh, Phat Voong Vinh, Maude Richard J., Baker Stephen, Wiersinga W. Joost, van der Poll Tom, Day Nicholas P., Dondorp Arjen M. The diagnostic accuracy of three rapid diagnostic tests for typhoid fever at Chittagong Medical College Hospital, Chittagong, Bangladesh Tropical medicine & international health 2015;20 (10):1376-1384 [PubMed]
  • Huson Michaëla A. M., Grobusch Martin P., van der Poll Tom The effect of HIV infection on the host response to bacterial sepsis Lancet infectious diseases 2015;15 (1):95-108 [PubMed]
  • Huson Michaëla A. M., Kalkman Rachel, Stolp Sebastiaan M., Janssen Saskia, Alabi Abraham S., Beyeme Justin O., van der Poll Tom, Grobusch Martin P. The impact of HIV on presentation and outcome of bacterial sepsis and other causes of acute febrile illness in Gabon Infection 2015;43 (4):443-451 [PubMed]
  • de Vos Alex F., Dessing Mark C., Lammers Adriana J. J., de Porto Alexander P. N. A., Florquin Sandrine, de Boer Onno J., de Beer Regina, Terpstra Sanne, Bootsma Hester J., Hermans Peter W., van 't Veer Cornelis, van der Poll Tom The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice PLoS ONE 2015;10 (2):e0118181 [PubMed]
  • Westendorp Willeke F., Vermeij Jan-Dirk, Zock Elles, Hooijenga Imke J., Kruyt Nyika D., Bosboom Hans J. L. W., Kwa Vincent I. H., Weisfelt Martijn, Remmers Michel J. M., ten Houten Robert, Schreuder A. H. C. M. Tobien, Vermeer Sarah E., van Dijk Ewout J., Dippel Diederik W. J., Dijkgraaf Marcel G. W., Spanjaard Lodewijk, Vermeulen Marinus, van der Poll Tom, Prins Jan M., Vermeij Frederique H., Roos Yvo B. W. E. M., Kleyweg Ruud P., Kerkhoff Henk, Brouwer Matthijs C., Zwinderman Aeilko H., van de Beek Diederik, Nederkoorn Paul J., Vermeij J.-D., Kerkhoff H., Bosboom J. L. W., Kwa V. I. H., Weisfelt M., Remmers M. J. M., van Dijk E. J., Vermeij F., Schreuder A., Vermeer S. E., ten Houten R., Dippel D. W. J., Kappelle L. J., van der Worp H. B., Merkies I. S. J., de Bruijn S. F. T. M., de Laat K. F., Haag Den, Jellema K., Keizer K., de Rijk M. C., Vermeij A. J., de Gans K. The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial Lancet 2015;385 (9977):1519-1526 [PubMed]
  • Achouiti Ahmed, van't Veer Cornelis, de Vos Alex F., van der Poll Tom The receptor for advanced glycation end products promotes bacterial growth at distant body sites in Staphylococcus aureus skin infection Microbes and infection / Institut Pasteur 2015;17 (9):622-627 [PubMed]
  • de Stoppelaar S. F., Claushuis T. A. M., Jansen M. P. B., Hou B., Roelofs J. J. T. H., van 't Veer C., van der Poll T. The role of platelet MyD88 in host response during gram-negative sepsis Journal of thrombosis and haemostasis 2015;13 (9):1709-1720 [PubMed]
  • de Boer Johannes Daan The role of the Protein C system in allergic and non-allergic lung inflammation 2015. 304p. ISBN 9789462038042. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van der Zee J. S., van 't Veer C.)
  • van der Meer Anne J., Scicluna Brendon P., Moerland Perry D., Lin Jiang, Jacobson Eric W., Vlasuk George P., van der Poll Tom The Selective Sirtuin 1 Activator SRT2104 Reduces Endotoxin-Induced Cytokine Release and Coagulation Activation in Humans Critical care medicine 2015;43 (6):e199-e202 [PubMed]
  • van den Boogaard Florry Engelina The tissue factor pathway in pneumonia 2015. 261p. ISBN 9789461696564. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Schultz M. J.; Co-supervisor: van 't Veer C.)
  • Mook-Kanamori B. B., Valls Serón M., Geldhoff M., Havik S. R., van der Ende A., Baas F., van der Poll T., Meijers J. C. M., P Morgan B., Brouwer M. C., van de Beek D. Thrombin-activatable fibrinolysis inhibitor influences disease severity in humans and mice with pneumococcal meningitis Journal of thrombosis and haemostasis 2015;13 (11):2076-2086 [PubMed]
  • van den Boogaard Florry E., Schouten Marcel, de Stoppelaar Sacha F., Roelofs Joris J. T. H., Brands Xanthe, Schultz Marcus J., van't Veer Cornelis, van der Poll Tom Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia Critical care medicine 2015;43 (3):e75-e83 [PubMed]
  • van Lieshout Miriam H. P., Florquin Sandrine, Vanʼt Veer Cornelis, de Vos Alex F., van der Poll Tom TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-x03B3 Journal of innate immunity 2015;7 (6):637-646 [PubMed]
  • Bakker Pieter J., Scantlebery Angelique M., Butter Loes M., Claessen Nike, Teske Gwendoline J. D., van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion PLoS ONE 2015;10 (9):e0137511 [PubMed]
  • Blok Dana Christa Toll-like receptor and associated regulators in pneumonia and sepsis 2015. 164p. ISBN 9789461696823. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)
  • Hommes Tijmen Johannes TREM receptors in infection and inflammation 2015. 182p. ISBN 9789461697660. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)

2014

  • Kager Liesbeth M., Runge Jurgen H., Nederveen Aart J., Roelofs Joris J. T. H., Stoker Jaap, Maas Mario, van der Poll Tom A new murine model to study musculoskeletal tuberculosis (short communication) Tuberculosis (Edinburgh, Scotland) 2014;94 (3):306-310 [PubMed]
  • Levi Marcel, van der Poll Tom A short contemporary history of disseminated intravascular coagulation Seminars in thrombosis and hemostasis 2014;40 (8):874-880 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., de Boer Onno J., Weiler Hartmut, van 't Veer Cornelis, van der Poll Tom A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis) PLoS neglected tropical diseases 2014;8 (4):e2819 [PubMed]
  • Kager Liesbeth M. Coagulation and fibrinolysis in tuberculosis, melioidosis and beyond 2014. 329p. ISBN 9789462034792. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van 't Veer C., Wiersinga W. J.)
  • Huson Michaëla A. M., Stolp Sebastiaan M., van der Poll Tom, Grobusch Martin P. Community-acquired bacterial bloodstream infections in HIV-infected patients: a systematic review Clinical infectious diseases 2014;58 (1):79-92 [PubMed]
  • Schouten Judith, Wit Ferdinand W., Stolte Ineke G., Kootstra Neeltje A., van der Valk Marc, Geerlings Suzanne E., Prins Maria, Reiss Peter, Kooij K. W., van Zoest R. A., Elsenga B. C., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Gras L. A. J., van Leeuwen E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study Clinical infectious diseases 2014;59 (12):1787-1797 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., van 't Veer Cornelis, van der Poll Tom Deficiency of protease-activated receptor-1 limits bacterial dissemination during severe Gram-negative sepsis (melioidosis) Microbes and infection / Institut Pasteur 2014;16 (2):171-174 [PubMed]
  • Hommes Tijmen J., Hoogendijk Arie J., Dessing Mark C., van't Veer Cornelis, Florquin Sandrine, de Vos Alex F., van der Poll Tom DNAX-Activating Protein of 12 kDa Impairs Host Defense in Pneumococcal Pneumonia Critical care medicine 2014;42 (12):E783-E790 [PubMed]
  • Majoor Christof J., van de Pol Marianne A., Kamphuisen Pieter Willem, Meijers Joost C. M., Molenkamp Richard, Wolthers Katja C., van der Poll Tom, Nieuwland Rienk, Johnston Sebastian L., Sterk Peter J., Bel Elisabeth H. D., Lutter Rene, van der Sluijs Koenraad F. Evaluation of coagulation activation after rhinovirus infection in patients with asthma and healthy control subjects: an observational study Respiratory research 2014;15 (1):14 [PubMed]
  • Wensink Annette C., Kemp Vera, Fermie Job, García Laorden M. Isabel, van der Poll Tom, Hack C. Erik, Bovenschen Niels Granzyme K synergistically potentiates LPS-induced cytokine responses in human monocytes Proceedings of the National Academy of Sciences of the United States of America 2014;111 (16):5974-5979 [PubMed]
  • van Lieshout Miriam H. P., Anas Adam A., Florquin Sandrine, Hou Baidong, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis PLoS pathogens 2014;10 (9):e1004368 [PubMed]
  • Wiersinga Willem Joost, Leopold Stije J., Cranendonk Duncan R., van der Poll Tom Host innate immune responses to sepsis Virulence 2014;5 (1):36-44 [PubMed]
  • Petoumenos K., Reiss P., Ryom L., Rickenbach M., Sabin C. A., El-Sadr W., d'Arminio Monforte A., Phillips A. N., de Wit S., Kirk O., Dabis F., Pradier C., Lundgren J. D., Law M. G., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Mansfeld M., Nielsen J., Raben D., Brandt R. Salbøl, Fanti I., Krum E., Hillebregt M., Geffard S., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Goorhuis A., Hovius J. W. R. Increased risk of cardiovascular disease (CVD) with age in HIV-positive men: a comparison of the D:A:D CVD risk equation and general population CVD risk equations HIV medicine 2014;15 (10):595-603 [PubMed]
  • Duitman Jan Willem Infectious diseases and fibrotic disorders: potential novel targets 2014. 194p. ISBN 9789088918636. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Florquin Sandrine, van der Poll Tom; Co-supervisors: Spek Arnold, Peppelenbosch M. P.)
  • de Jong Hanna K., Koh Gavin C. K. W., van Lieshout Miriam H. P., Roelofs Joris J. T. H., van Dissel Jaap T., van der Poll Tom, Wiersinga W. Joost Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection BMC immunology 2014;15 (1):30 [PubMed]
  • de Boer J. Daan, Yang Jack, van den Boogaard Florry E., Hoogendijk Arie J., de Beer Regina, van der Zee Jaring S., Roelofs Joris J. T. H., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Mast cell-deficient kit mice develop house dust mite-induced lung inflammation despite impaired eosinophil recruitment Journal of innate immunity 2014;6 (2):219-226 [PubMed]
  • van den Boogaard Florry E., Brands Xanthe, Roelofs Joris J. T. H., de Beer Regina, de Boer Onno J., van 't Veer Cornelis, van der Poll Tom Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia Journal of infectious diseases 2014;210 (9):1376-1384 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., Stroo Ingrid, Achouiti Ahmed, van 't Veer Cornelis, Conway Edward M., van der Poll Tom Mice Lacking the Lectin-Like Domain of Thrombomodulin Are Protected Against Melioidosis Critical care medicine 2014;42 (3):E221-E230 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, Endeman Henrik, Mortensen Brittany L., Laterre Pierre-Francois, Wittebole Xavier, van Zoelen Marieke A. D., Zhang Yaofang, Hoogerwerf Jacobien J., Florquin Sandrine, Schultz Marcus J., Grutters Jan C., Biesma Douwe H., Roth Johannes, Skaar Eric P., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia Thorax 2014;69 (11):1034-1042 [PubMed]
  • van Lieshout Miriam H., Scicluna Brendon P., Florquin Sandrine, van der Poll Tom NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia American journal of respiratory cell and molecular biology 2014;50 (4):699-712 [PubMed]
  • Lodi Sara, Del Amo Julia, Moreno Santiago, Bucher Heiner C., Furrer Hansjakob, Logan Roger, Sterne Jonathan, Pérez-Hoyos Santiago, Jarrín Inma, Phillips Andrew, Olson Ashley, Van Sighem Ard, Reiss Peter, Sabin Caroline, Jose Sophie, Justice Amy, Goulet Joseph, Miró José M., Ferrer Elena, Meyer Laurence, Seng Rémonie, Vourli Georgia, Antoniadou Anastasia, Dabis Francois, Vandenhede Mari Anne, Costagliola Dominique, Abgrall Sophie, Hernán Miguel A., Hernan Miguel, Bansi L., Hill T., Sabin C., Dunn D., Porter K., Glabay A., Gras L. A.J., Kuijpers T. W., Scherpbier H. J., Van Der Meer J. T.M., Wit F. W.M.N., Van Der Poll T., Nellen F. J.B., Geerlings S. E., Van Vugt M., Pajkrt D., Bos J. C., Van Der Valk M., Grijsen M. L., Wiersinga W. J., Lauw F. N. Opportunistic infections and AIDS malignancies early after initiating combination antiretroviral therapy in high-income countries AIDS (London, England) 2014;28 (16):2461-2473 [PubMed]
  • de Boer Johannes Daan, Kager Liesbeth M., Roelofs Joris J. T. H., Meijers Joost C. M., de Boer Onno J., Weiler Hartmut, Isermann Berend, van 't Veer Cornelis, van der Poll Tom Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia BMC infectious diseases 2014;14 (1):559 [PubMed]
  • de Boer J. Daan, van't Veer Cornelis, Stroo Ingrid, van der Meer Anne J., de Vos Alex F., van der Zee Jaring S., Roelofs Joris J. T. H., van der Poll Tom Protease-activated receptor-2 deficient mice have reduced house dust mite-evoked allergic lung inflammation Innate immunity 2014;20 (6):618-625 [PubMed]
  • Wagemakers A., Mason L. M. K., Oei A., de Wever B., van der Poll T., Bins A. D., Hovius J. W. R. Rapid outer-surface protein C DNA tattoo vaccination protects against Borrelia afzelii infection Gene therapy 2014;21 (12):1051-1057 [PubMed]
  • Blok Dana C., van Lieshout Miriam H. P., Hoogendijk Arie J., Florquin Sandrine, de Boer Onno J., Garlanda Cecilia, Mantovani Alberto, van't Veer Cornelis, de Vos Alex F., van der Poll Tom Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae Journal of innate immunity 2014;6 (4):542-552 [PubMed]
  • Piet Jurgen R., Geldhoff Madelijn, van Schaik Barbera D. C., Brouwer Matthijs C., Valls Seron Mercedes, Jakobs Marja E., Schipper Kim, Pannekoek Yvonne, Zwinderman Aeilko H., van der Poll Tom, van Kampen Antoine H. C., Baas Frank, van der Ende Arie, van de Beek Diederik Streptococcus pneumoniae arginine synthesis genes promote growth and virulence in pneumococcal meningitis Journal of infectious diseases 2014;209 (11):1781-1791 [PubMed]
  • van der Meer Jonathan H. M., van der Poll Tom, van 't Veer Cornelis TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis Blood 2014;123 (16):2460-2469 [PubMed]
  • Lin Cong, Duitman Janwillem, Daalhuisen Joost, ten Brink Marieke, von der Thüsen Jan, van der Poll Tom, Borensztajn Keren, Spek C. Arnold Targeting protease activated receptor-1 with P1pal-12 limits bleomycin-induced pulmonary fibrosis Thorax 2014;69 (2):152-160 [PubMed]
  • van der Poll Tom, Herwald Heiko The coagulation system and its function in early immune defense Thrombosis and haemostasis 2014;112 (4):640-648 [PubMed]
  • Kager Liesbeth Martine, van der Poll Tom, Wiersinga Willem Joost The coagulation system in melioidosis: from pathogenesis to new treatment strategies Expert review of anti-infective therapy 2014;12 (8):993-1002 [PubMed]
  • van Vught L. A., Endeman H., Meijvis S. C., Zwinderman A. H., Scicluna B. P., Biesma D. H., van der Poll T. The effect of age on the systemic inflammatory response in patients with community-acquired pneumonia Clinical microbiology and infection 2014;20 (11):1183-1188 [PubMed]
  • Schouten Marcel, de Boer J. Daan, Kager Liesbeth M., Roelofs Joris J. T. H., Meijers Joost C. M., Esmon Charles T., Levi Marcel, van 't Veer Cornelis, van der Poll Tom The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsis Thrombosis and haemostasis 2014;111 (5):970-980 [PubMed]
  • Schouten Marcel The protein C system in severe infection 2014. 307p. ISBN 9789090281155. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Levi M. M.; Co-supervisor: van 't Veer C.)
  • Kuipers Maria T., Aslami Hamid, Tuinman Pieter Roel, Tuip-de Boer Anita M., Jongsma Geartsje, van der Sluijs Koenraad F., Choi Goda, Wolthuis Esther K., Roelofs Joris J. T. H., Bresser Paul, Schultz Marcus J., van der Poll Tom, Wieland Catharina W. The receptor for advanced glycation end products in ventilator-induced lung injury Intensive Care Medicine Experimental 2014;2 (1):22 [PubMed]
  • van der Poll Tom The remarkable career of leptin: from antidote to obesity to mediator of lung inflammation Critical care medicine 2014;42 (2):490-492 [PubMed]
  • de Stoppelaar Sacha F., van 't Veer Cornelis, van der Poll Tom The role of platelets in sepsis Thrombosis and haemostasis 2014;112 (4):666-677 [PubMed]
  • Du Jiangfeng, Nicolaes Gerry Af, Kruijswijk Danielle, Versloot Miranda, van der Poll Tom, van 't Veer Cornelis The structure function of the death domain of human IRAK-M Cell communication and signaling 2014;12 (1):77 [PubMed]
  • Kager Liesbeth M., de Vos Alex F., Roelofs Joris J. T. H., van der Loos Chris M., de Boer Onno J., van't Veer Cornelis, Conway Edward M., van der Poll Tom The thrombomodulin lectin-like domain does not change host responses to tuberculosis Thrombosis and haemostasis 2014;111 (2):345-353 [PubMed]
  • de Stoppelaar Sacha F., van 't Veer Cornelis, Claushuis Theodora A. M., Albersen Bregje J. A., Roelofs Joris J. T. H., van der Poll Tom Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice Blood 2014;124 (25):3781-3790 [PubMed]
  • Kuipers Maria Theresa, Jongsma Geartsje, Hegeman Maria A., Tuip-de Boer Anita M., Wolthuis Esther K., Choi Goda, Bresser Paul, van der Poll Tom, Schultz Marcus J., Wieland Catharina W. TLR2 deficiency aggravates lung injury caused by mechanical ventilation Shock (Augusta, Ga.) 2014;42 (1):60-64 [PubMed]
  • van Lieshout Miriam H. P., van der Poll Tom, van't Veer Cornelis TLR4 inhibition impairs bacterial clearance in a therapeutic setting in murine abdominal sepsis Inflammation research 2014;63 (11):927-933 [PubMed]
  • Smith Colette J., Ryom Lene, Weber Rainer, Morlat Philippe, Pradier Christian, Reiss Peter, Kowalska Justyna D., de Wit Stephane, Law Matthew, El Sadr Wafaa, Kirk Ole, Friis-Moller Nina, Monforte Antonella d'Arminio, Phillips Andrew N., Sabin Caroline A., Lundgren Jens D., Powderly B., Shortman N., Moecklinghoff C., Reilly G., Franquet X., Ryom L., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Mansfeld M., Nielsen J., Raben D., Lundgren J. D., Salbøl Brandt R., Rickenbach M., Fanti I., Krum E., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., van der Valk M. Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration Lancet 2014;384 (9939):241-248 [PubMed]
  • Hommes Tijmen J., Hoogendijk Arie J., Dessing Mark C., van't Veer Cornelis, Florquin Sandrine, Colonna Marco, de Vos Alex F., van der Poll Tom Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia Journal of pathology 2014;233 (4):357-367 [PubMed]
  • van der Poll Tom Tumor Necrosis Factor Inhibition in Severe Sepsis: A Promise Not Fulfilled Critical care medicine 2014;42 (3):724-725 [PubMed]
  • Westendorp Willeke F., Vermeij Jan-Dirk, Dippel Diederik W. J., Dijkgraaf Marcel G. W., van der Poll Tom, Prins Jan M., Vermeij Frederique H., Roos Yvo B. W. E. M., Brouwer Matthijs C., Zwinderman Aeilko H., van de Beek Diederik, Nederkoorn Paul J. Update of the Preventive Antibiotics in Stroke Study (PASS): statistical analysis plan Trials 2014;15 (1):382 [PubMed]
  • Westendorp Willeke F., Vermeij Jan-Dirk, van Geloven Nan, Dippel Diederik W. J., Dijkgraaf Marcel G. W., van der Poll Tom, Prins Jan M., Spanjaard Lodewijk, Vermeij Frederique H., Nederkoorn Paul J., van de Beek Diederik Update on the Preventive Antibiotics in Stroke Study (PASS): a randomised controlled phase 3 clinical trial Trials 2014;15 (1):133 [PubMed]

2013

  • Hoogendijk Arie J., Pinhanços Sandra S., van der Poll Tom, Wieland Catharina W. AMP-activated protein kinase activation by 5-aminoimidazole-4-carbox-amide-1-β-D-ribofuranoside (AICAR) reduces lipoteichoic acid-induced lung inflammation Journal of biological chemistry 2013;288 (10):7047-7052 [PubMed]
  • Ryom Lene, Mocroft Amanda, Kirk Ole, Worm Signe W., Kamara David A., Reiss Peter, Ross Michael, Fux Christoph A., Morlat Philippe, Moranne Olivier, Smith Colette, Lundgren Jens D., Dabis F., El-Sadr W., Pradier C., Kirk O., Weber R., Law M., Morfeldt L., de Wit S., Calvo G., d'Arminio Monforte A., Shortman N., Butcher D., Rode R., Franquet X., Powderly W., Sabin C. A., Phillips A., Lundgren J. D., Ryom L., Kamara D. A., Smith C., Mocroft A., Tverland J., Nielsen J., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., van der Valk M. Association between antiretroviral exposure and renal impairment among HIV-positive persons with normal baseline renal function: the D:A:D study Journal of infectious diseases 2013;207 (9):1359-1369 [PubMed]
  • Sabin Caroline A., Ryom Lene, de Wit Stephane, Mocroft Amanda, Phillips Andrew N., Worm Signe W., Weber Rainer, D'Arminio Monforte Antonella, Reiss Peter, Kamara David, El-Sadr Wafaa, Pradier Christian, Dabis Francois, Law Matthew, Lundgren Jens, Shortman N., Butcher D., Rode R., Franquet X., Powderly W., Ryom L., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Nielsen J., Lundgren J. D., Brandt R. Salbøl, Rickenbach M., Fanti I., Krum E., Hillebregt M., Geffard S., Sundström A., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., van der Valk M. Associations between immune depression and cardiovascular events in HIV infection AIDS (London, England) 2013;27 (17):2735-2748 [PubMed]
  • Glas G. J., van der Sluijs K. F., Schultz M. J., Hofstra J.-J. H., van der Poll T., Levi M. [=Marcel M.] Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome Journal of thrombosis and haemostasis 2013;11 (1):17-25 [PubMed]
  • Duitman Janwillem, Schouten Marcel, Groot Angelique P., Borensztajn Keren S., Daalhuisen Joost B., Florquin Sandrine, van der Poll Tom, Spek C. Arnold CCAAT/enhancer-binding protein delta facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner (vol 109, pg 9113, 2012) Proceedings of the National Academy of Sciences of the United States of America 2013;110 (37):15163 [PubMed]
  • Duitman Jan Willem, Hoogendijk Arie J., van der Poll Tom, Spek C. Arnold CCAAT/enhancer-binding protein δ: multifaceted regulator in respiratory disease American journal of pathology 2013;182 (4):1459-1460 [PubMed]
  • Smit Mikaela, Smit Colette, Geerlings Suzanne, Gras Luuk, Brinkman Kees, Hallett Timothy B., de Wolf Frank, Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Lowe S., Schreij G., Oude Lashof A., Posthouwer D., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., tot Pannerden M. H. Nispen, Verbon A., Rijnders B. J. A., van Gorp E. C. M., Hassing R. J., Smeulders A. W. M., Hartwig N. G., Driessen G. J. A., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., Soetekouw R., ten Kate R. W. Changes in first-line cART regimens and short-term clinical outcome between 1996 and 2010 in The Netherlands PLoS ONE 2013;8 (9):e76071 [PubMed]
  • Rotger Margalida, Glass Tracy R., Junier Thomas, Lundgren Jens, Neaton James D., Poloni Estella S., van 't Wout Angélique B., Lubomirov Rubin, Colombo Sara, Martinez Raquel, Rauch Andri, Günthard Huldrych F., Neuhaus Jacqueline, Wentworth Deborah, van Manen Danielle, Gras Luuk A., Schuitemaker Hanneke, Albini Laura, Torti Carlo, Jacobson Lisa P., Li Xiuhong, Kingsley Lawrence A., Carli Federica, Guaraldi Giovanni, Ford Emily S., Sereti Irini, Hadigan Colleen, Martinez Esteban, Arnedo Mireia, Egaña-Gorroño Lander, Gatell Jose M., Law Matthew, Bendall Courtney, Petoumenos Kathy, Rockstroh Jürgen, Reiss Peter, Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M. Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons Clinical infectious diseases 2013;57 (1):112-121 [PubMed]
  • Levi Marcel, van der Poll Tom Disseminated intravascular coagulation: a review for the internist Internal and emergency medicine 2013;8 (1):23-32 [PubMed]
  • de jager Cornelis P. C., Gemen Eugenie F. A., Leuvenink Jacqueline, Hilbink Mirrian, Laheij Robert J. F., van der Poll Tom, Wever Peter C. Dynamics of peripheral blood lymphocyte subpopulations in the acute and subacute phase of Legionnaires' disease PLoS ONE 2013;8 (4):e62265 [PubMed]
  • Kuipers Maria T. Endogenous danger signals in ventilator-induced lung injury 2013. 223p. ISBN 9789461694607. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schultz M. J., van der Poll T.; Co-supervisor: Wieland C. W.)
  • Kager L. M., Wiersinga W. J., Roelofs J. J., Meijers J. C. M., Zeerleder S. S., Esmon C. T., van't Veer C., van der Poll T. Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis) Journal of thrombosis and haemostasis 2013;11 (2):282-292 [PubMed]
  • Kager Liesbeth M., Weehuizen Tassili A., Wiersinga W. Joost, Roelofs Joris J. T. H., Meijers Joost C. M., Dondorp Arjen M., van 't Veer Cornelis, van der Poll Tom Endogenous α2-antiplasmin is protective during severe gram-negative sepsis (melioidosis) American journal of respiratory and critical care medicine 2013;188 (8):967-975 [PubMed]
  • Levi Marcel, van der Poll Tom Endothelial injury in sepsis Intensive care medicine 2013;39 (10):1839-1842 [PubMed]
  • Schuijt Tim J., Bakhtiari Kamran, Daffre Sirlei, Deponte Kathleen, Wielders Simone J. H., Marquart J. Arnoud, Hovius Joppe W., van der Poll Tom, Fikrig Erol, Bunce Matthew W., Camire Rodney M., Nicolaes Gerry A. F., Meijers Joost C. M., van 't Veer Cornelis Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein Circulation 2013;128 (3):254-266 [PubMed]
  • Koh Gavin C. K. W., Weehuizen Tassili A., Breitbach Katrin, Krause Kathrin, de Jong Hanna K., Kager Liesbeth M., Hoogendijk Arjan J., Bast Antje, Peacock Sharon J., van der Poll Tom, Steinmetz Ivo, Wiersinga W. Joost Glyburide reduces bacterial dissemination in a mouse model of melioidosis PLoS neglected tropical diseases 2013;7 (10):e2500 [PubMed]
  • Gras Luuk, Geskus Ronald B., Jurriaans Suzanne, Bakker Margreet, van Sighem Ard, Bezemer Daniela, Fraser Christophe, Prins Jan M., Berkhout Ben, de Wolf Frank, Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Vrouenraets S. M. E., Pajkrt D., Bos J. C., van der Valk M., Schreij G., Lowe S., Oude Lashof A., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., van der Feltz M., Nouwen J. L., Gelinck L. B. S., Verbon A., Rijnders B. J. A., van de Ven-de Ruiter E. D., Slobbe L., Kauffmann R. H., Schippers E. F., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., ten Kate R. W., Soetekouw R., Kroon F. P., van den Broek P. J. Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM? PLoS ONE 2013;8 (5):e64437 [PubMed]
  • Kuipers Maria T., Vogl Thomas, Aslami Hamid, Jongsma Geartsje, van den Berg Elske, Vlaar Alexander P. J., Roelofs Joris J. T. H., Juffermans Nicole P., Schultz Marcus J., van der Poll Tom, Roth Johannes, Wieland Catharina W. High levels of S100A8/A9 proteins aggravate ventilator-induced lung injury via TLR4 signaling PLoS ONE 2013;8 (7):e68694 [PubMed]
  • Achouiti Ahmed, van der Meer Anne Jan, Florquin Sandrine, Yang Huan, Tracey Kevin J., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia Critical care (London, England) 2013;17 (6):R296 [PubMed]
  • Zhang Xinglin, Top Janetta, de Been Mark, Bierschenk Damien, Rogers Malbert, Leendertse Masja, Bonten Marc J. M., van der Poll Tom, Willems Rob J. L., van Schaik Willem Identification of a genetic determinant in clinical Enterococcus faecium strains that contributes to intestinal colonization during antibiotic treatment Journal of infectious diseases 2013;207 (11):1780-1786 [PubMed]
  • Geldhoff Madelijn, Mook-Kanamori Barry B., Brouwer Matthijs C., Troost Dirk, Leemans Jaklien C., Flavell Richard A., van der Ende Arie, van der Poll Tom, van de Beek Diederik Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis BMC infectious diseases 2013;13 (1):358 [PubMed]
  • Klein Klouwenberg Peter M. C., Ong David S. Y., Bos Lieuwe D. J., de Beer Friso M., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Straat Marleen, van Vught Lonneke A., Wieske Luuk, Horn Janneke, Schultz Marcus J., van der Poll Tom, Bonten Marc J. M., Cremer Olaf L. Interobserver agreement of Centers for Disease Control and Prevention criteria for classifying infections in critically ill patients Critical care medicine 2013;41 (10):2373-2378 [PubMed]
  • Kager Liesbeth M., de Boer J. Daan, Bresser Paul, van der Zee Jaring S., Zeerleder Sacha, Meijers Joost C. M., van 't Veer Cornelis, van der Poll Tom Intrabronchial activated protein C enhances lipopolysaccharide-induced pulmonary responses European respiratory journal 2013;42 (1):188-197 [PubMed]
  • Hoogendijk Arie Johan, Pinhanços Sandra Sofia, van der Poll Tom, Wieland Catharina Wilhelmina Intrapulmonary administration of a p38 mitogen activated protein kinase inhibitor partially prevents pulmonary inflammation Immunobiology 2013;218 (4):435-442 [PubMed]
  • Blok Dana C., van der Sluijs Koenraad F., Florquin Sandrine, de Boer Onno J., van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia PLoS ONE 2013;8 (3):e58191 [PubMed]
  • Achouiti Ahmed, de Vos Alex F., de Beer Regina, Florquin Sandrine, van 't Veer Cornelis, van der Poll Tom Limited role of the receptor for advanced glycation end products during Streptococcus pneumoniae bacteremia Journal of innate immunity 2013;5 (6):603-612 [PubMed]
  • Daan de Boer J., Roelofs Joris J. T. H., de Vos Alex F., de Beer Regina, Schouten Marcel, Hommes Tijmen J., Hoogendijk Arie J., de Boer Onno J., Stroo Ingrid, van der Zee Jaring S., Veer Cornelis Van't, van der Poll Tom Lipopolysaccharide inhibits Th2 lung inflammation induced by house dust mite allergens in mice American journal of respiratory cell and molecular biology 2013;48 (3):382-389 [PubMed]
  • Schoffelen Annelot F., van Lelyveld Steven F. L., Barth Roos E., Gras Luuk, de Wolf Frank, Netea Mihai G., Hoepelman Andy I. M., Prins J. M., Kuijpers T. W., Scherpbier H. J., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Lowe S., Schreij G., Oude Lashof A., Posthouwer D., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., Nouwen J. L., Nispen tot Pannerden M. H., Verbon A., Rijnders B. J. A., van Gorp E. C. M., Hassing R. J., Smeulders A. W. M., Hartwig N. G., Driessen G. J. A., Branger J., Schippers E. F., van Nieuwkoop C., van Elzakker E. P., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., Soetekouw R. Lower incidence of Pneumocystis jirovecii pneumonia among Africans in the Netherlands host or environmental factors? AIDS (London, England) 2013;27 (7):1179-1184 [PubMed]
  • de Jager C. P. C. Markers of infectious disease emergencies. Focus on patients with community-acquired pneumonia 2013. 204p. ISBN 9789090274324. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Wever P. C.)
  • Tilson Hugh, Primatesta Paola, Kim Dennis, Rauer Barbara, Hawkins Philip N., Hoffman Hal M., Kuemmerle-Deschner Jasmin, van der Poll Tom, Walker Ulrich A. Methodological challenges in monitoring new treatments for rare diseases: lessons from the cryopyrin-associated periodic syndrome registry Orphanet journal of rare diseases 2013;8 (1):139 [PubMed]
  • Hofstra Jorrit J., Cornet Alexander D., Declerck Paul J., Dixon Barry, Aslami Hamid, Vlaar Alexander P. J., Roelofs Joris J., van der Poll Tom, Levi Marcel, Schultz Marcus J. Nebulized fibrinolytic agents improve pulmonary fibrinolysis but not inflammation in rat models of direct and indirect acute lung injury PLoS ONE 2013;8 (2):e55262 [PubMed]
  • Worm Signe W., Bower Mark, Reiss Peter, Bonnet Fabrice, Law Matthew, Fätkenheuer Gerd, D'Arminio Monforte Antonella, Abrams Donald I., Grulich Andrew, Fontas Eric, Kirk Ole, Furrer Hansjakob, de Wit Stephane, Phillips Andrew, Lundgren Jens D., Sabin Caroline A., Shortman N., Butcher D., Rode R., Franquet X., Powderly W., Ryom L., Sabin C. A., Kamara D., Smith C., Phillips A., Mocroft A., Tverland J., Nielsen J., Lundgren J. D., Brandt R. Salbøl, Rickenbach M., Fanti I., Krum E., Hillebregt M., Geffard S., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., van der Valk M. Non-AIDS defining cancers in the D:A:D Study--time trends and predictors of survival: a cohort study BMC infectious diseases 2013;13 (1):471 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., de Boer Onno J., Meijers Joost C. M., Isermann Berend, van't Veer Cornelis, van der Poll Tom Overexpression of activated protein C is detrimental during severe experimental gram-negative sepsis (melioidosis) Critical care medicine 2013;41 (10):e266-e274 [PubMed]
  • Kager Liesbeth M., Schouten Marcel, Wiersinga W. Joost, de Boer J. Daan, Lattenist Lionel C. W., Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, Dondorp Arjen M., Esmon Charles T., van 't Veer Cornelis, van der Poll Tom Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis) PLoS neglected tropical diseases 2013;7 (7):e2306 [PubMed]
  • de Stoppelaar S. F., van't Veer C., van den Boogaard F. E., Nieuwland R., Hoogendijk A. J., de Boer O. J., Roelofs J. J. T. H., van der Poll T. Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice Thrombosis and haemostasis 2013;110 (3):582-592 [PubMed]
  • Heijmans J., Büller N. V. J. A., Hoff E., Dihal A. A., van der Poll T., van Zoelen M. A. D., Bierhaus A., Biemond I., Hardwick J. C. H., Hommes D. W., Muncan V., van den Brink G. R. Rage signalling promotes intestinal tumourigenesis Oncogene 2013;32 (9):1202-1206 [PubMed]
  • Blok Dana C., de Vos Alex F., Florquin Sandrine, van der Poll Tom Role of interleukin 1 receptor like 1 (ST2) in gram-negative and gram-positive sepsis in mice Shock (Augusta, Ga.) 2013;40 (4):290-296 [PubMed]
  • Scicluna Brendon P., van 't Veer Cornelis, Nieuwdorp Max, Felsmann Karen, Wlotzka Britta, Stroes Erik S. G., van der Poll Tom Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome PLoS ONE 2013;8 (11):e79051 [PubMed]
  • Achouiti Ahmed, Föll Dirk, Vogl Thomas, van Till Jan W. O., Laterre Pierre-François, Dugernier Thierry, Wittebole Xavier, Boermeester Marja A., Roth Johannes, van der Poll Tom, van Zoelen Marieke A. D. S100A12 and soluble receptor for advanced glycation end products levels during human severe sepsis Shock (Augusta, Ga.) 2013;40 (3):188-194 [PubMed]
  • Levi Marcel, Schultz Marcus, van der Poll Tom Sepsis and thrombosis Seminars in thrombosis and hemostasis 2013;39 (5):559-566 [PubMed]
  • Angus Derek C., van der Poll Tom Severe Sepsis and Septic Shock New England journal of medicine 2013;369 (9):840-851 [PubMed]
  • Angus Derek C., van der Poll Tom Severe sepsis and septic shock [author's reply] New England journal of medicine 2013;369 (21):2063 [PubMed]
  • de Stoppelaar Sacha F., Bootsma Hester J., Zomer Aldert, Roelofs Joris J. T. H., Hermans Peter W. M., van 't Veer Cornelis, van der Poll Tom Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia PLoS ONE 2013;8 (11):e80062 [PubMed]
  • Kager Liesbeth M., Roelofs Joris J. T. H., de Vos Alex F., Wieland Catharina W., Schouten Marcel, Meijers Joost C. M., Isermann Berend, van't Veer Cornelis, Esmon Charles T., van der Poll Tom The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis Thrombosis and haemostasis 2013;109 (4):726-737 [PubMed]
  • van der Poll Tom The endothelial protein C receptor and malaria Blood 2013;122 (5):624-625 [PubMed]
  • Top Janetta, Paganelli Fernanda L., Zhang Xinglin, van Schaik Willem, Leavis Helen L., van Luit-Asbroek Miranda, van der Poll Tom, Leendertse Masja, Bonten Marc J. M., Willems Rob J. L. The Enterococcus faecium enterococcal biofilm regulator, EbrB, regulates the esp operon and is implicated in biofilm formation and intestinal colonization PLoS ONE 2013;8 (5):e65224 [PubMed]
  • Schuijt Tim J., van der Poll Tom, de Vos Willem M., Wiersinga W. Joost The intestinal microbiota and host immune interactions in the critically ill Trends in microbiology 2013;21 (5):221-229 [PubMed]
  • Schouten Marcel, de Boer J. Daan, van 't Veer Cornelis, Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, Conway Edward M., van der Poll Tom The lectin-like domain of thrombomodulin hampers host defence in pneumococcal pneumonia European respiratory journal 2013;41 (4):935-942 [PubMed]
  • Levi M. [=Marcel M.], van der Poll T. Thrombomodulin in sepsis Minerva anestesiologica 2013;79 (3):294-298 [PubMed]

2012

  • de Boer J. Daan, Majoor Christof J., van 't Veer Cornelis, Bel Elisabeth H. D., van der Poll Tom Asthma and coagulation Blood 2012;119 (14):3236-3244 [PubMed]
  • Duitman Janwillem, Hoogendijk Arie J., Groot Angelique P., Ruela de Sousa Roberta R., van der Poll Tom, Florquin Sandrine, Spek C. Arnold CCAAT-Enhancer Binding Protein Delta (C/EBP delta) Protects Against Klebsiella pneumoniae-Induced Pulmonary Infection: Potential Role for Macrophage Migration Journal of infectious diseases 2012;206 (12):1826-1835 [PubMed]
  • Duitman Janwillem, Schouten Marcel, Groot Angelique P., Daalhuisen Joost B., Florquin Sandrine, van der Poll Tom, Spek C. Arnold CCAAT/enhancer-binding protein delta facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner Proceedings of the National Academy of Sciences of the United States of America 2012;109 (23):9113-9118 [PubMed]
  • Mook-Kanamori Barry, Geldhoff Madelijn, Troost Dirk, van der Poll Tom, van de Beek Diederik Characterization of a pneumococcal meningitis mouse model BMC infectious diseases 2012;12 (1):71 [PubMed]
  • Paris D. H., Chansamouth V., Nawtaisong P., Löwenberg E. C., Phetsouvanh R., Blacksell S. D., Lee S. J., Dondorp A. M., van der Poll T., Newton P. N., Levi M. [=Marcel M.], Day N. P. J. Coagulation and inflammation in scrub typhus and murine typhusu-a prospective comparative study from Laos Clinical microbiology and infection 2012;18 (12):1221-1228 [PubMed]
  • van der Poll Tom, Levi Marcel Crosstalk between Inflammation and Coagulation: The Lessons of Sepsis Current vascular pharmacology 2012;10 (5):632-638 [PubMed]
  • Hoogendijk Arie J., Kuipers Maria T., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. CYCLIN-DEPENDENT KINASE INHIBITION REDUCES LUNG DAMAGE IN A MOUSE MODEL OF VENTILATOR-INDUCED LUNG INJURY Shock (Augusta, Ga.) 2012;38 (4):375-380 [PubMed]
  • van Lieshout Miriam H. P., Blok Dana C., Wieland Catharina W., de Vos Alex F., van 't Veer Cornelis, van der Poll Tom Differential Roles of MyD88 and TRIF in Hematopoietic and Resident Cells During Murine Gram-Negative Pneumonia Journal of infectious diseases 2012;206 (9):1415-1423 [PubMed]
  • Schouten M., van 't Veer C., van der Poll T., Levi M. [=Marcel M.] Effect of the factor V Leiden mutation on the incidence and outcome of severe infection and sepsis Netherlands journal of medicine 2012;70 (7):306-310 [PubMed]
  • Kager Liesbeth M., Wiersinga W. Joost, Roelofs Joris J. T. H., Meijers Joost C. M., Levi Marcel, van't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator impairs host defense during severe experimental gram-negative sepsis (melioidosis) Critical care medicine 2012;40 (7):2168-2175 [PubMed]
  • Van Der Poll Tom Experimental human sepsis models Drug Discovery Today: Disease Models 2012;9 (1):e3-e9
  • Weehuizen Tassili A. F., Wieland Catharina W., van der Windt Gerritje J. W., Duitman Jan-Willem, Boon Louis, Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga W. Joost Expression and Function of Transforming Growth Factor beta in Melioidosis Infection and immunity 2012;80 (5):1853-1857 [PubMed]
  • Reynier Frederic, de Vos Alex F., Hoogerwerf Jacobien J., Bresser Paul, van der Zee Jaring S., Paye Malick, Pachot Alexandre, Mougin Bruno, van der Poll Tom Gene Expression Profiles in Alveolar Macrophages Induced by Lipopolysaccharide in Humans Molecular medicine (Cambridge, Mass.) 2012;18 (9):1303-1311 [PubMed]
  • May Margaret T., Hogg Robert S., Justice Amy C., Shepherd Bryan E., Costagliola Dominique, Ledergerber Bruno, Thiébaut Rodolphe, Gill M. John, Kirk Ole, van Sighem Ard, Saag Michael S., Navarro Gemma, Sobrino-Vegas Paz, Lampe Fiona, Ingle Suzanne, Guest Jodie L., Crane Heidi M., D'Arminio Monforte Antonella, Vehreschild Jörg J., Sterne Jonathan A. C., Gras L. A., van Sighem A. I., Smit C., de Wolf F., Prins J. M., Bos J. C., Eeftinck-Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., Olszyna D. P., van der Poll T., Reiss P., Sankatsing S. U. C., van der Valk M., Vermeulen J. N., Vrouenraets S. M. E., van Vugt M., Wit F. W. M. N., Kuijpers T. W., Pajkrt D., Scherpbier H. J., Hoornenborg E., Back N. K. T., Zaaijer H. L., Berkhout B., Jurriaans S., van Kan H. J. M. Heterogeneity in outcomes of treated HIV-positive patients in Europe and North America: relation with patient and cohort characteristics International journal of epidemiology 2012;41 (6):1807-1820 [PubMed]
  • de Jong Hanna K., Parry Chris M., van der Poll Tom, Wiersinga W. Joost Host-Pathogen Interaction in Invasive Salmonellosis PLoS pathogens 2012;8 (10):e1002933 [PubMed]
  • del Amo Julia, Moreno Santiago, Bucher Heiner C., Furrer Hansjakob, Logan Roger, Sterne Jonathan, Pérez-Hoyos Santiago, Jarrín Inma, Phillips Andrew, Lodi Sara, van Sighem Ard, de Wolf Frank, Sabin Caroline, Bansi Loveleen, Justice Amy, Goulet Joseph, Miró José M., Ferrer Elena, Meyer Laurence, Seng Rémonie, Toulomi Giota, Gargalianos Panagiotis, Costagliola Dominique, Abgrall Sophie, Hernán Miguel A., Ainsworth J., Anderson J., Babiker A., Delpech V., Dunn D., Easterbrook P., Fisher M., Gazzard B., Gras L. A. J., Prins J. M., Boer K., Bos J. C., Geerlings S. E., Godfried M. H., Kuijpers T. W., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., Pajkrt D., van der Poll T., Reiss P., Scherpbier H. J., van der Valk M., Wit F. W. M. N., van Vugt M. Impact of antiretroviral therapy on tuberculosis incidence among HIV-positive patients in high-income countries Clinical infectious diseases 2012;54 (9):1364-1372 [PubMed]
  • Wiersinga Willem J., van der Poll Tom Infectie en onstekingin: A. B. J. Groeneveld, M. J. Schultz, M. B. Vroom, editors. Handboek multiorgaanfalen. Utrecht: De Tijdstroom; 2012., ISBN 9789058981912
  • Levi Marcel, van der Poll Tom, Schultz Marcus Infection and Inflammation as Risk Factors for Thrombosis and Atherosclerosis Seminars in thrombosis and hemostasis 2012;38 (5):506-514 [PubMed]
  • Hoogerwerf Jacobien J., van der Windt Gerritje J. W., Blok Dana C., Hoogendijk Arie J., de Vos Alex F., van 't Veer Cornelis, Florquin Sandrine, Kobayashi Koichi S., Flavell Richard A., van der Poll Tom Interleukin-1 Receptor-Associated Kinase M-Deficient Mice Demonstrate an Improved Host Defense during Gram-negative Pneumonia Molecular medicine (Cambridge, Mass.) 2012;18 (7):1067-1075 [PubMed]
  • van der Windt Gerritje J. W., Blok Dana C., Hoogerwerf Jacobien J., Lammers Adriana J. J., de Vos Alex F., van't Veer Cornelis, Florquin Sandrine, Kobayashi Koichi S., Flavell Richard A., van der Poll Tom Interleukin 1 Receptor-Associated Kinase M Impairs Host Defense During Pneumococcal Pneumonia Journal of infectious diseases 2012;205 (12):1849-1857 [PubMed]
  • Scicluna Brendon P., van der Poll Tom Interleukin-27: a potential new sepsis biomarker exposed through genome-wide transcriptional profiling Critical care (London, England) 2012;16 (6):188 [PubMed]
  • Hoogendijk Arie Johan Kinome activity profiling and kinase modulation of pulmonary inflammation 2012. 133p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll Tom; Co-supervisor: Wieland Catharina W.)
  • van Lelyveld Steven F. L., Gras Luuk, Kesselring Anouk, Zhang Shuangjie, de Wolf Frank, Wensing Annemarie M. J., Hoepelman Andy I. M., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M., Grijsen M. L., Wiersinga W. J., Schreij G., Lowe S., Oude Lashof A., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., van der Feltz M., Nouwen J. L., Gelinck L. B. S., Verbon A., Rijnders B. J. A., Slobbe L., van Gorp E. C. M., Hartwig N. G., Driessen G. J. A., Branger J., Schippers E. F., van Nieuwkoop C., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., ten Kate R. W., Soetekouw R. Long-term complications in patients with poor immunological recovery despite virological successful HAART in Dutch ATHENA cohort AIDS (London, England) 2012;26 (4):465-474 [PubMed]
  • Achouiti Ahmed, Vogl Thomas, Urban Constantin F., Röhm Marc, Hommes Tijmen J., van Zoelen Marieke A. D., Florquin Sandrine, Roth Johannes, van 't Veer Cornelis, de Vos Alex F., van der Poll Tom Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis PLoS pathogens 2012;8 (10):e1002987 [PubMed]
  • Levi M. [=Marcel M.], van der Poll T., Schultz M. New insights into pathways that determine the link between infection and thrombosis Netherlands journal of medicine 2012;70 (3):114-120 [PubMed]
  • Kager Liesbeth M., van der Windt Gerritje J. W., Wieland Catharina W., Florquin Sandrine, van 't Veer Cornelis, van der Poll Tom Plasminogen activator inhibitor type I may contribute to transient, non-specific changes in immunity in the subacute phase of murine tuberculosis Microbes and infection / Institut Pasteur 2012;14 (9):748-755 [PubMed]
  • van der Poll Tom Preclinical Sepsis Models Surgical infections 2012;13 (5):287-292 [PubMed]
  • Petoumenos Kathy, Worm Signe W., Fontas Eric, Weber Rainer, de Wit Stephane, Bruyand Mathias, Reiss Peter, El-Sadr Wafaa, D'Arminio Monforte Antonella, Friis-Møller Nina, Lundgren Jens D., Law Matthew G., Collins S., Shortman N., Butcher D., Rode R., Powderly W., Worm S. W., Sabin C. A., Kamara D., Ellefson M., Smith C., Tverland J., Nielsen J., Mocroft A., Lundgren J. D., Salbøl Brandt R., Rickenbach M., Fanti L., Krum E., Hillebregt M., Geffard S., Sundström A., Delforge M., Fontas E., Torres F., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., van der Valk M. Predicting the short-term risk of diabetes in HIV-positive patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study Journal of the International AIDS Society 2012;15 (2):17426 [PubMed]
  • Kuipers Maria T., Aslami Hamid, Vlaar Alexander P. J., Juffermans Nicole P., Tuip-de Boer Anita M., Hegeman Maria A., Jongsma Geartsje, Roelofs Joris J. T. H., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. Pre-Treatment with Allopurinol or Uricase Attenuates Barrier Dysfunction but Not Inflammation during Murine Ventilator-Induced Lung Injury PLoS ONE 2012;7 (11):e50559 [PubMed]
  • Schouten Marcel, van't Veer Cornelis, Roelofs Joris J. T. H., Levi Marcel, van der Poll Tom Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study Critical care (London, England) 2012;16 (6):R238 [PubMed]
  • Dessing Mark C., Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., van der Poll Tom, Yang Huan, Tracey Kevin J., Nawroth Peter P., Bierhaus Angelika, Florquin Sandrine, Leemans Jaklien C. RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury Journal of innate immunity 2012;4 (1):80-85 [PubMed]
  • van Zoelen Marieke A. D., Wieland Catharina W., van der Windt Gerritje J. W., Florquin Sandrine, Nawroth Peter P., Bierhaus Angelika, van der Poll Tom Receptor for advanced glycation end products is protective during murine tuberculosis Molecular immunology 2012;52 (3-4):183-189 [PubMed]
  • Hoogendijk Arie J., Roelofs Joris J. T. H., Duitman Janwillem, van Lieshout Miriam H. P., Blok Dana C., van der Poll Tom, Wieland Catharina W. R-roscovitine Reduces Lung Inflammation Induced by Lipoteichoic Acid and Streptococcus pneumoniae Molecular medicine (Cambridge, Mass.) 2012;18 (7):1086-1095 [PubMed]
  • Levi Marcel, van der Poll Tom, Schultz Marcus Systemic versus localized coagulation activation contributing to organ failure in critically ill patients Seminars in immunopathology 2012;34 (1):167-179 [PubMed]
  • Cain Lauren E., Phillips Andrew, Lodi Sara, Sabin Caroline, Bansi Loveleen, Justice Amy, Tate Janet, Logan Roger, Robins James M., Sterne Jonathan A. C., van Sighem Ard, de Wolf Frank, Bucher Heiner C., Elzi Luigia, Touloumi Giota, Vourli Georgia, Esteve Anna, Casabona Jordi, del Amo Julia, Moreno Santiago, Seng Rémonie, Meyer Laurence, Pérez-Hoyos Santiago, Muga Roberto, Abgrall Sophie, Costagliola Dominique, Hernán Miguel A., Ainsworth J., Anderson J., Babiker A., Chadwick D., Delpech V., Dunn D., Gras L. A. J., Prins J. M., Boer K., Bos J. C., Geerlings S. E., Godfried M. H., Kuijpers T. W., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., Pajkrt D., van der Poll T., Reiss P., Scherpbier H. J., van der Valk M., van Vugt M., Wit F. W. M. N. The effect of efavirenz versus nevirapine-containing regimens on immunologic, virologic and clinical outcomes in a prospective observational study AIDS (London, England) 2012;26 (13):1691-1705 [PubMed]
  • Koh G. C. K. W., Peacock S. J., van der Poll T., Wiersinga W. J. The impact of diabetes on the pathogenesis of sepsis European journal of clinical microbiology & infectious diseases 2012;31 (4):379-388 [PubMed]
  • de jager Cornelis P. C., Wever Peter C., Gemen Eugenie F. A., Kusters Ron, van Gageldonk-Lafeber Arianne B., van der Poll Tom, Laheij Robert J. F. The Neutrophil-Lymphocyte Count Ratio in Patients with Community-Acquired Pneumonia PLoS ONE 2012;7 (10):e46561 [PubMed]
  • Lammers Adriana J. J., de Porto Alexander P. N. A., de Boer Onno J., Florquin Sandrine, van der Poll Tom The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen BMC infectious diseases 2012;12 (1):139 [PubMed]
  • Kuipers Maria T., Aslami Hamid, Janczy John R., van der Sluijs Koenraad F., Vlaar Alexander P. J., Wolthuis Esther K., Choi Goda, Roelofs Joris J. T. H., Flavell Richard A., Sutterwala Fayyaz S., Bresser Paul, Leemans Jaklien C., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome Anesthesiology 2012;116 (5):1104-1115 [PubMed]

2011

  • Stephan Femke, Hazelzet Jan A., Bulder Ingrid, Boermeester Marja A., van Till Jw Olivier, van der Poll Tom, Wuillemin Walter A., Aarden Lucien A., Zeerleder Sacha Activation of factor VII-activating protease in human inflammation: a sensor for cell death Critical care (London, England) 2011;15 (2):R110 [PubMed]
  • van Westerloo David J., Choi Goda, Löwenberg Ester C., Truijen Jasper, de Vos Alex F., Endert Erik, Meijers Joost C. M., Zhou Lu, Pereira Manuel Pfl, Queiroz Karla C. S., Diks Sander H., Levi Marcel, Peppelenbosch Maikel P., van der Poll Tom Acute Stress Elicited by Bungee Jumping Suppresses Human Innate Immunity Molecular medicine (Cambridge, Mass.) 2011;17 (3-4):180-188 [PubMed]
  • Veninga Henrike, Hoek Robert M., de Vos Alex F., de Bruin Alex M., An Feng-Qi, van der Poll Tom, van Lier René A. W., Medof M. Edward, Hamann Jörg A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense PLoS ONE 2011;6 (10):e24431 [PubMed]
  • Schuijt Tim J., Coumou Jeroen, Narasimhan Sukanya, Dai Jianfeng, Deponte Kathleen, Wouters Diana, Brouwer Mieke, Oei Anneke, Roelofs Joris J. T. H., van Dam Alje P., van der Poll Tom, van't Veer Cornelis, Hovius Joppe W., Fikrig Erol A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent Cell host & microbe 2011;10 (2):136-146 [PubMed]
  • Truijen Jasper, Davis Shyrin C. A. T., Stok Wim J., Kim Yu-Sok, van Westerloo David J., Levi Marcel, van der Poll Tom, Westerhof Berend E., Karemaker John M., van Lieshout Johannes J. Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade Clinical science (London, England 2011;120 (4):161-167 [PubMed]
  • Kuipers Maria T., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. Bench-to-bedside review: Damage-associated molecular patterns in the onset of ventilator-induced lung injury Critical care (London, England) 2011;15 (6):235 [PubMed]
  • Agar Cetin, de Groot Philip G., Mörgelin Matthias, Monk Stephanie D. D. C., van Os Gwendolyn M. A., Levels Johannes H. M., de Laat Bas, Urbanus Rolf T., Herwald Heiko, van der Poll Tom, Meijers Joost C. M. beta(2)-Glycoprotein I: a novel component of innate immunity Blood 2011;117 (25):6939-6947 [PubMed]
  • van der Windt Gerritje J. W., Schouten Marcel, Zeerleder Sacha, Florquin Sandrine, van der Poll Tom CD44 Is Protective during Hyperoxia-Induced Lung Injury American journal of respiratory cell and molecular biology 2011;44 (3):377-383 [PubMed]
  • Levi Marcel, Schultz Marcus, van der Poll Tom Coagulation Biomarkers in Critically Ill Patients Critical care clinics 2011;27 (2):281-+ [PubMed]
  • Skattum Lillemor, van Deuren Marcel, van der Poll Tom, Truedsson Lennart Complement deficiency states and associated infections Molecular immunology 2011;48 (14):1643-1655 [PubMed]
  • van 't Veer Cornelis, van den Pangaart Petra S., Kruijswijk Daniëlle, Florquin Sandrine, de Vos Alex F., van der Poll Tom Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli Journal of biological chemistry 2011;286 (42):36603-36618 [PubMed]
  • Koh Gavin C. K. W., Meijers Joost C. M., Maude Rapeephan R., Limmathurotsakul Direk, Day Nicholas P. J., Peacock Sharon J., van der Poll Tom, Wiersinga Willem J. Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis) Thrombosis and haemostasis 2011;106 (6):1139-1148 [PubMed]
  • van Zoelen Marieke A. D., Verstege Marleen I., Draing Christian, de Beer Regina, Veer Cornelis Van't, Florquin Sandrine, Bresser Paul, van der Zee Jaring S., te Velde Anje A., von Aulock Sonja, van der Poll Tom Endogenous MCP-1 promotes lung inflammation induced by LPS and LTA Molecular immunology 2011;48 (12-13):1468-1476 [PubMed]
  • Schouten M., van't Veer C., Levi M. [=Marcel M.], Esmon C. T., van der Poll T. Endogenous protein C inhibits activation of coagulation and transiently lowers bacterial outgrowth in murine Escherichia coli peritonitis Journal of thrombosis and haemostasis 2011;9 (5):1072-1075 [PubMed]
  • Lammers Adriana J., de Porto Alexander P., Florquin Sandrine, de Boer Onno J., Bootsma Hester J., Hermans Peter W., van der Poll Tom Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule Immunobiology 2011;216 (8):863-870 [PubMed]
  • van der Crabben Saskia N., Stegenga Michiel E., Blümer Regje M. E., Ackermans Mariëtte T., Endert Erik, Tanck Michael W. T., Serlie Mireille J., van der Poll Tom, Sauerwein Hans P. Erythrocyte glutathione concentration and production during hyperinsulinemia, hyperglycemia, and endotoxemia in healthy humans Metabolism: clinical and experimental 2011;60 (1):99-106 [PubMed]
  • Schouten M., van der Sluijs K. F., Roelofs J. J. T. H., Levi M., van't Veer C., van der Poll T. Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza (vol 36, pg 1346, 2010) European respiratory journal 2011;37 (3):726
  • Levi Marcel, Schouten Marcel, van't Veer Cees, van der Poll Tom Factor v Leiden mutation in severe infection and sepsis Seminars in thrombosis and hemostasis 2011;37 (8):955-960 [PubMed]
  • Koh Gavin C. K. W., Maude Rapeephan R., Schreiber M. Fernanda, Limmathurotsakul Direk, Wiersinga W. Joost, Wuthiekanun Vanaporn, Lee Sue J., Mahavanakul Weera, Chaowagul Wipada, Chierakul Wirongrong, White Nicholas J., van der Poll Tom, Day Nicholas P. J., Dougan Gordon, Peacock Sharon J. Glyburide Is Anti-inflammatory and Associated with Reduced Mortality in Melioidosis Clinical infectious diseases 2011;52 (6):717-725 [PubMed]
  • Wieland C. W., van Lieshout M. H. P., Hoogendijk A. J., van der Poll T. Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2 European respiratory journal 2011;37 (4):848-857 [PubMed]
  • Schuijt Tim J., Narasimhan Sukanya, Daffre Sirlei, Deponte Kathleen, Hovius Joppe W. R., Veer Cornelis Van't, van der Poll Tom, Bakhtiari Kamran, Meijers Joost C. M., Boder Eric T., van Dam Alje P., Fikrig Erol Identification and Characterization of Ixodes scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display PLoS ONE 2011;6 (1):e15926 [PubMed]
  • Benard Antoine, van Sighem Ard, Taieb Audrey, Valadas Emilia, Ruelle Jean, Soriano Vicente, Calmy Alexandra, Balotta Claudia, Damond Florence, Brun-Vezinet Françoise, Chene Geneviève, Matheron Sophie, Tubiana Roland, Meyohas Marie-Caroline, Bernasconi Cornélia, Dupin Nicolas, Slama Laurence, Ponscarme Diane, Lascoux-Combe Caroline, Timsit Françoise-Julie, Khuong Marie-Aude, Rami Agathe, Teichner Elina, Semaille Caroline, Quertainmont Yann, Bloch Martine, Froguel Eric, Genet Philippe, Leprêtre Annie, Zucman David, Karmochkine Marina, Blum Laurent, Chevojon Pierre, Gras L. A. J., Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Wit F. W. M. N., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Pajkrt D., Bos J. C., van der Valk M. Immunovirological response to triple nucleotide reverse-transcriptase inhibitors and ritonavir-boosted protease inhibitors in treatment-naive HIV-2-infected patients: The ACHIEV2E Collaboration Study Group Clinical infectious diseases 2011;52 (10):1257-1266 [PubMed]
  • Schouten Marcel, de Boer J. Daan, van der Sluijs Koenraad F., Roelofs Joris J. T. H., van't Veer Cornelis, Levi Marcel, Esmon Charles T., van der Poll Tom Impact of Endogenous Protein C on Pulmonary Coagulation and Injury during Lethal H1N1 Influenza in Mice American journal of respiratory cell and molecular biology 2011;45 (4):789-794 [PubMed]
  • Hoogendijk Arie J., Diks Sander H., Peppelenbosch Maikel P., van der Poll Tom, Wieland Catharina W. Kinase activity profiling of gram-negative pneumonia Molecular medicine (Cambridge, Mass.) 2011;17 (7-8):741-747 [PubMed]
  • Hoogendijk Arie J., Diks Sander H., van der Poll Tom, Peppelenbosch Maikel P., Wieland Catharina W. Kinase Activity Profiling of Pneumococcal Pneumonia PLoS ONE 2011;6 (4):e18519 [PubMed]
  • Hoogerwerf Jacobien J., Leendertse Masja, Wieland Catharina W., de Vos Alex F., de Boer J. Daan, Florquin Sandrine, van der Poll Tom Loss of Suppression of Tumorigenicity 2 (ST2) Gene Reverses Sepsis-induced Inhibition of Lung Host Defense in Mice American journal of respiratory and critical care medicine 2011;183 (7):932-940 [PubMed]
  • Gras Luuk, van Sighem Ard, Bezemer Daniela, Smit Colette, Wit Ferdinand, de Wolf Frank, Prins J. M., Kuijpers T. W., Scherpbier H. J., Boer K., van der Meer J. T. M., Godfried M. H., Reiss P., van der Poll T., Nellen F. J. B., Lange J. M. A., Geerlings S. E., van Vugt M., Vrouenraets S. M. E., Pajkrt D., Bos J. C., van der Valk M., Schreij G., Lowe S., Oude Lashof A., Pronk M. J. H., Bravenboer B., van der Ende M. E., de Vries-Sluijs T. E. M. S., Schurink C. A. M., van der Feltz M., Nouwen J. L., Gelinck L. B. S., Verbon A., Rijnders B. J. A., Slobbe L., Hartwig N. G., Driessen G. J. A., Branger J., Kauffmann R. H., Schippers E. F., Groeneveld P. H. P., Alleman M. A., Bouwhuis J. W., ten Kate R. W., Soetekouw R., Kroon F. P., van den Broek P. J., van Dissel J. T., Arend S. M. Lower mortality and earlier start of combination antiretroviral therapy in patients tested repeatedly for HIV than in those with a positive first test AIDS (London, England) 2011;25 (6):813-818 [PubMed]
  • Schuijt T. J., Hovius J. W., van der Poll T., van Dam A. P., Fikrig E. Lyme borreliosis vaccination: the facts, the challenge and the future Trends in parasitology 2011;27 (1):40-47 [PubMed]
  • Van Der Poll T. Management of serious pneumococcal pneumonia - Pathogenesis Reanimation 2011;20 (SUPPL.2):418-421
  • Cornet Alexander D., Hofstra Jorrit J., Vlaar Alexander P., van den Boogaard Floor E., Roelofs Joris J., van der Poll Tom, Levi Marcel, Groeneveld A. B. Johan, Schultz Marcus J. Nebulized anticoagulants limit coagulopathy but not inflammation in pseudomonas aeruginosa-induced pneumonia in rats Shock (Augusta, Ga.) 2011;36 (4):417-423 [PubMed]
  • van der Windt Gerritje J. W., Hoogendijk Arie J., Schouten Marcel, Hommes Tijmen J., de Vos Alex F., Florquin Sandrine, van der Poll Tom Osteopontin Impairs Host Defense During Pneumococcal Pneumonia Journal of infectious diseases 2011;203 (12):1850-1858 [PubMed]
  • Mook-Kanamori Barry B., Geldhoff Madelijn, van der Poll Tom, van de Beek Diederik Pathogenesis and pathophysiology of pneumococcal meningitis Clinical microbiology reviews 2011;24 (3):557-591 [PubMed]
  • Kager L. M., Wiersinga W. J., Roelofs J. J. T. H., Meijers J. C. M., Levi M. [=Marcel M.], van't Veer C., van der Poll T. Plasminogen activator inhibitor type I contributes to protective immunity during experimental Gram-negative sepsis (melioidosis) Journal of thrombosis and haemostasis 2011;9 (10):2020-2028 [PubMed]
  • Goris Marga G. A., Wagenaar Jiri F. P., Hartskeerl Rudy A., van Gorp Eric C. M., Schuller Simone, Monahan Avril M., Nally Jarlath E., van der Poll Tom, van 't Veer Cornelis Potent Innate Immune Response to Pathogenic Leptospira in Human Whole Blood PLoS ONE 2011;6 (3):e18279 [PubMed]
  • Hofstra Jorrit J., Vlaar Alexander P., Knape Paul, Mackie Dave P., Determann Rogier M., Choi Goda, van der Poll Tom, Levi Marcel, Schultz Marcus J. Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma Journal of trauma 2011;70 (6):1389-1397 [PubMed]
  • van Zoelen Marieke A. D., Achouiti Ahmed, van der Poll Tom RAGE during infectious diseases Frontiers in bioscience (Scholar edition) 2011;3:1119-1132 [PubMed]
  • Schouten Marcel, van 't Veer Cornelis, Roelofs Joris J. T. H., Gerlitz Bruce, Grinnell Brian W., Levi Marcel, van der Poll Tom Recombinant activated protein C attenuates coagulopathy and inflammation when administered early in murine pneumococcal pneumonia Thrombosis and haemostasis 2011;106 (6):1189-1196 [PubMed]
  • van den Boogaard F. E., Brands X., Schultz M. J., Levi M. [=Marcel M.], Roelofs J. J. T. H., van 't Veer C., van der Poll T. Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia Journal of thrombosis and haemostasis 2011;9 (1):122-132 [PubMed]
  • van der Poll Tom, van Zoelen Marieke A. D., Wiersinga W. Joost Regulation of pro- and anti-inflammatory host responses Contributions to microbiology 2011;17:125-136 [PubMed]
  • Lammers Jolanda Splenic studies: prevention of pneumococcal disease on organisational, clinical and experimental level 2011. 160p. ISBN 9789085708599. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Speelman P., van der Poll T.; Co-supervisors: Hoekstra J. B. L., Lombarts M. J. M. H.)
  • Boer Kees, Smit Colette, van der Flier Michiel, de Wolf Frank, Bezemer D. O., Gras L. A. J., Kesselring A. M., van Sighem A. I., Smit C., Zhang S., Zaheri S., Bronsveld W., Hillebrand-Haverkort M. E., Prins J. M., Branger J., Eeftinck Schattenkerk J. K. M., Gisolf J., Godfried M. H., Lange J. M. A., Lettinga K. D., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Reiss P., Ruys Th A., Steingrover R., van Twillert G., Vermeulen J. N., Vrouenraets S. M. E., van Vugt M., Wit F. W. M. N., Kuijpers T. W., Pajkrt D., Scherpbier H. J., van Eeden A., Brinkman K., van den Berk G. E. L., Blok W. L., Frissen P. H. J., Roos J. C., Schouten W. E. M., Bekendam D. J., Weigel H. M., Mulder J. W., van Gorp E. C. M., Wagenaar J., Veenstra J., Danner S. A., van Agtmael M. A., Claessen F. A. P. The comparison of the performance of two screening strategies identifying newly-diagnosed HIV during pregnancy European journal of public health 2011;21 (5):632-637 [PubMed]
  • van der Poll Tom, Boer Johannes Daan de, Levi Marcel The effect of inflammation on coagulation and vice versa Current opinion in infectious diseases 2011;24 (3):273-278 [PubMed]
  • van der Windt Gerritje J. W., Hoogendijk Arie J., de Vos Alex F., Kerver Marjolein E., Florquin Sandrine, van der Poll Tom The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia Laboratory investigation; a journal of technical methods and pathology 2011;91 (4):588-597 [PubMed]
  • van Zoelen Marieke A. D., Achouiti Ahmed, van der Poll Tom The role of receptor for advanced glycation endproducts (RAGE) in infection Critical care (London, England) 2011;15 (2):208 [PubMed]
  • van der Poll Tom Thrombin and diabetic nephropathy Blood 2011;117 (19):5015-5016 [PubMed]
  • Schuijt Tim J. Tick proteins in Borrelia. Transmission and tick feeding <t(r)ick or treat? > 2011. 186p. ISBN 9789057762277. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Kroes A. C. M.; Co-supervisors: Fikrig E., Hovius J. W. H., van Dam A. P.)
  • Coumou J., van der Poll T., Speelman P., Hovius J. W. R. Tired of Lyme borreliosis Lyme borreliosis in the Netherlands Netherlands journal of medicine 2011;69 (3):101-111 [PubMed]
  • Cain Lauren E., Logan Roger, Robins James M., Sterne Jonathan A. C., Sabin Caroline, Bansi Loveleen, Justice Amy, Goulet Joseph, van Sighem Ard, de Wolf Frank, Bucher Heiner C., von Wyl Viktor, Esteve Anna, Casabona Jordi, del Amo Julia, Moreno Santiago, Seng Remonie, Meyer Laurence, Perez-Hoyos Santiago, Muga Roberto, Lodi Sara, Lanoy Emilie, Costagliola Dominique, Hernan Miguel A., Ainsworth J., Anderson J., Babiker A., Delpech V., Dunn D., Easterbrook P., Fisher M., Gazzard B., Gilson R., Gras L. A. J., Prins J. M., Boer K., Bos J. C., Geerlings S. E., Godfried M. H., Kuijpers T. W., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., Pajkrt D., van der Poll T., Reiss P., Scherpbier H. J., van der Valk M., van Vugt M., Wit F. W. M. N. When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study Annals of internal medicine 2011;154 (8):509-515 [PubMed]

2010

  • Schouten Marcel, van der Sluijs Koenraad F., Gerlitz Bruce, Grinnell Brian W., Roelofs Joris J. T. H., Levi Marcel M., van 't Veer Cornelis, van der Poll Tom Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study Critical care (London, England) 2010;14 (2):R65 [PubMed]
  • van der Sluijs Koenraad F., van der Poll Tom, Lutter René, Juffermans Nicole P., Schultz Marcus J. Bench-to-bedside review: Bacterial pneumonia with influenza - pathogenesis and clinical implications Critical care (London, England) 2010;14 (2):219 [PubMed]
  • van der Windt Gerritje J. W., van 't Veer Cornelis, Florquin Sandrine, van der Poll Tom CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages Infection and immunity 2010;78 (1):115-124 [PubMed]
  • van der Windt Gerritje J. W., Florquin Sandrine, de Vos Alex F., van't Veer Cornelis, Queiroz Karla C. S., Liang Jiurong, Jiang Dianhua, Noble Paul W., van der Poll Tom CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia American journal of pathology 2010;177 (5):2483-2494 [PubMed]
  • Stegenga Michiel E., Vincent Jean-Louis, Vail George M., Xie Jin, Haney Douglas J., Williams Mark D., Bernard Gordon R., van der Poll Tom Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis Critical care medicine 2010;38 (2):539-545 [PubMed]
  • Joosten Leo A. B., van de Veerdonk Frank L., Vonk Alieke G., Boerman Otto C., Keuter Monique, Fantuzzi Giamilla, Verschueren Ineke, van der Poll Tom, Dinarello Charles A., Kullberg Bart Jan, van der Meer Jos W. M., Netea Mihai G. Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I APMIS 2010;118 (12):1000-1007 [PubMed]
  • Levi Marcel, Schultz Marcus, van der Poll Tom Disseminated Intravascular Coagulation in Infectious Disease Seminars in thrombosis and hemostasis 2010;36 (4):367-377 [PubMed]
  • Wiersinga W. Joost, Calandra Thierry, Kager Liesbeth M., van der Windt Gerritje J. W., Roger Thierry, le Roy Didier, Florquin Sandrine, Peacock Sharon J., Sweep Fred C. G. J., van der Poll Tom Expression and Function of Macrophage Migration Inhibitory Factor (MIF) in Melioidosis PLoS neglected tropical diseases 2010;4 (2):e605 [PubMed]
  • Schouten M., van der Sluijs K. F., Roelofs J. J. T. H., Levi M. [=Marcel M.], van't Veer C., van der Poll T. Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza European respiratory journal 2010;36 (6):1346-1354 [PubMed]
  • Hoogerwerf Jacobien J., van Zoelen Marieke A., Wiersinga W. Joost, van 't Veer Cornelis, de Vos Alex F., de Boer Anita, Schultz Marcus J., Hooibrink Berend, de Jonge Evert, van der Poll Tom Gene Expression Profiling of Apoptosis Regulators in Patients with Sepsis Journal of innate immunity 2010;2 (5):461-468 [PubMed]
  • Worm Signe W., Friis-Møller Nina, Bruyand Mathias, D'Arminio Monforte Antonella, Rickenbach Martin, Reiss Peter, El-Sadr Wafaa, Phillips Andrew, Lundgren Jens, Sabin Caroline, de Wolf F., Zaheri S., Gras L., Bronsveld W., Hillebrand-Haverkort M. E., Prins J. M., Bos J. C., Eeftinck Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van Leth F. C., Lowe S. H., van der Meer J. T. M., Nellen F. J. B., Pogány K., van der Poll T., Ruys Th A., Steingrover R., van Twillert G., van der Valk M., van Vonderen M. G. A., Vrouenraets S. M. E., van Vugt M., Wit F. W. M. N., van Eeden A., ten Veen J. H., van Dam P. S., Roos J. C., Brinkman K., Frissen P. H. J., Weigel H. M., Mulder J. W., van Gorp E. C. M., Meenhorst P. L., Mairuhu A. T. A., Veenstra J., Danner S. A., van Agtmael M. A., Claessen F. A. P. High prevalence of the metabolic syndrome in HIV-infected patients: impact of different definitions of the metabolic syndrome AIDS (London, England) 2010;24 (3):427-435 [PubMed]
  • Hoogerwerf Jacobien J. Immunotolerance during bacterial pneumonia and sepsis 2010. 171p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: de Vos A. F., van 't Veer C.)
  • Schouten Marcel, van 't Veer Cornelis, Roelofs Joris Jth, Levi Marcel, van der Poll Tom Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study Critical care (London, England) 2010;14 (4):R145 [PubMed]
  • Marshall John C., Abraham Edward, Adikhari Neill, Aikawa Naoki, al Rahma Hussain Nasser, Amin Pravin, Angus Derek C., Annane Djillali, Argent Andrew, Bernard Gordon R., Bertolini Guido, Bhagwanjee Satish, Burns Karen A., Calandra Thierry, Ceraso Daniel, Chan Kenneth, Chiche Jean-Daniel, Cobb J. Perren, Cook Deborah J., Cuthbertson Brian H., da Silva Eliezer, de Backer Daniel, Dellinger R. Phillip, Divatia Jigeeshu V., Fedson David, Festa Marino, Ferguson Niall D., Finfer Simon, Fowler Robert, Gomersall Charles, Granton John, Hammer Beth, Hudson Leonard D., Jimenez Edgar, Kissoon Niranjan, Koh Younsuck, Kumar Anand, Langer Martin, Latronico Nicola, Levy Mitchell M., Lowry Stephen, Mamdani Muhammad, Marsh Brian, McAuley Daniel F., Meduri G. Umberto, Menon David, Mira Jean-Paul, Morales-Alava Freddy, Moreno Rui, van der Poll Tom InFACT: a global critical care research response to H1N1 Lancet 2010;375 (9708):11-13 [PubMed]
  • Levi Marcel, van der Poll Tom Inflammation and coagulation Critical care medicine 2010;38 (2 Suppl):S26-S34 [PubMed]
  • van Sighem Ard I., Gras Luuk A. J., Reiss Peter, Brinkman Kees, de Wolf Frank, Bezemer D. O., Kesselring A. M., Smit C., Zhang S., Zaheri S., Prin J. M., Bos J. C., Eeftinck-Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Sankatsing S. U. C., van der Valk M., Vermeulen J. N., Vrouenraets S. M. E., van Vugt M., Wit F. W. M. N., Schreij G., van der Geest S., Oude Lashof A., Lowe S., Verbon A., Bravenboer B., Pronk M. J. H., Kuijpers T. W., Pajkrt D., Scherpbier H. J., van der Ende M. E., Bax H., van der Feltz M., Gelinck L. B. S., Nouwen J. L., Rijnders B. J. A., de Ruiter E. D., Slobbe L., Schurink C. A. M., de Vries-Sluijs T. E. M. S., Driessen G., Hartwig N. G., Branger J., Hoogewerf M. H., Hoornenborg E. Life expectancy of recently diagnosed asymptomatic HIV-infected patients approaches that of uninfected individuals AIDS (London, England) 2010;24 (10):1527-1535 [PubMed]
  • van Zoelen Marieke A. D., Achouiti Ahmed, Schmidt Ann-Marie, Yang Huan, Florquin Sandrine, Tracey Kevin J., van der Poll Tom Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis Critical care medicine 2010;38 (6):1414-1422 [PubMed]
  • de jager Cornelis P. C., van Wijk Paul T. L., Mathoera Rejiv B., de Jongh-Leuvenink Jacqueline, van der Poll Tom, Wever Peter C. Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit Critical care (London, England) 2010;14 (5):R192 [PubMed]
  • Hofstra Jorrit J., Vlaar Alexander P., Cornet Alexander D., Dixon Barry, Roelofs Joris J., Choi Goda, van der Poll Tom, Levi Marcel, Schultz Marcus J. Nebulized Anticoagulants Limit Pulmonary Coagulopathy, But Not Inflammation, in a Model of Experimental Lung Injury Journal of aerosol medicine and pulmonary drug delivery 2010;23 (2):105-111 [PubMed]
  • van der Windt Gerritje J. W., Wiersinga W. Joost, Wieland Catharina W., Tjia Ivo C. S. I., Day Nicholas P., Peacock Sharon J., Florquin Sandrine, van der Poll Tom Osteopontin Impairs Host Defense during Established Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis) PLoS neglected tropical diseases 2010;4 (8):e806 [PubMed]
  • van der Windt G. J. W., Hoogerwerf J. J., de Vos A. F., Florquin S., van der Poll T. Osteopontin promotes host defense during Klebsiella pneumoniae-induced pneumonia European respiratory journal 2010;36 (6):1337-1345 [PubMed]
  • Friis-Møller Nina, Thiébaut Rodolphe, Reiss Peter, Weber Rainer, Monforte Antonella D.'Arminio, de Wit Stephane, El-Sadr Wafaa, Fontas Eric, Worm Signe, Kirk Ole, Phillips Andrew, Sabin Caroline A., Lundgren Jens D., Law Matthew G., Collins S., Pearce G., Storfer S., Rhode R., Worm S. W., Sabin C. A., Friis-Møller N., Tverland J., Kamara A., Sjøl S., Lundgren J. D., Sawitz A., Brandt R. S., Rickenbach M., Fanti L., Krum E., Gras L., Geffard S., Sundström A., Delforge M., Fontas E., Torres F., McManus H., Wright S., Kjaer J., Prins J. M., Bos J. C., Geerlings S. E., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., van der Valk M., van Vugt M., Wit F. W. M. N. Predicting the risk of cardiovascular disease in HIV-infected patients: the data collection on adverse effects of anti-HIV drugs study European journal of cardiovascular prevention and rehabilitation 2010;17 (5):491-501 [PubMed]
  • Hoogerwerf Jacobien J., de Vos Alex F., van't Veer Cornelis, Bresser Paul, de Boer Anita, Tanck Michael W. T., Draing Christian, van der Zee Jaring S., van der Poll Tom Priming of Alveolar Macrophages upon Instillation of Lipopolysaccharide in the Human Lung American journal of respiratory cell and molecular biology 2010;42 (3):349-356 [PubMed]
  • Anas A. A., Wiersinga W. J., de Vos A. F., van der Poll T. Recent insights into the pathogenesis of bacterial sepsis Netherlands journal of medicine 2010;68 (4):147-152 [PubMed]
  • Anas Adam A., Hovius Joppe W. R., van 't Veer Cornelis, van der Poll Tom, de Vos Alex F. Role of CD14 in a Mouse Model of Acute Lung Inflammation Induced by Different Lipopolysaccharide Chemotypes PLoS ONE 2010;5 (4):e10183 [PubMed]
  • Anas Adam, van der Poll Tom, de Vos Alex F. Role of CD14 in lung inflammation and infection Critical care (London, England) 2010;14 (2):209 [PubMed]
  • Anas Adam, van der Poll Tom, de Vos Alex F. Role of CD14 in lung inflammation and infection Yearbook of intensive care and emergency medicine 2010;2010:129-140
  • Dessing Mark C., Butter Loes M., Teske Gwendoline J., Claessen Nike, van der Loos Chris M., Vogl Thomas, Roth Johannes, van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. S100A8/A9 Is Not Involved in Host Defense against Murine Urinary Tract Infection PLoS ONE 2010;5 (10):e13394 [PubMed]
  • Wiersinga W. Joost, Van Der Poll Tom Sepsis: Nieuwe inzichten in de pathogenese en behandeling Nederlands tijdschrift voor geneeskunde 2010;154 (6):268-275
  • Wiersinga W. J., van der Poll T. Sepsis: nieuwe inzichten in de pathogenese en behandeling Nederlands tijdschrift voor geneeskunde 2010;154 (6):A1130 [PubMed]
  • Hoogerwerf Jacobien J., Tanck Michael W. T., van Zoelen Marieke A. D., Wittebole Xavier, Laterre Pierre-François, van der Poll Tom Soluble ST2 plasma concentrations predict mortality in severe sepsis Intensive care medicine 2010;36 (4):630-637 [PubMed]
  • Wagenaar Jiri F. P. Studies on leptospirosis - clinical aspects and pathophysiology - 2010. 207p. ISBN 9789461080141. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisors: van Gorp E. C. M., Hartskeerl R. A., Gasem M. H.)
  • van der Poll Tom, Meijers Joost C. M. Systemic Inflammatory Response Syndrome and Compensatory Anti-Inflammatory Response Syndrome in Sepsis Journal of innate immunity 2010;2 (5):379-380 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Flierman Roelof, de Vos Alex F., Bonten Marc J. M., van der Poll Tom The Complement System Facilitates Clearance of Enterococcus faecium during Murine Peritonitis Journal of infectious diseases 2010;201 (4):544-552 [PubMed]
  • Yende Sachin, van der Poll Tom, Lee Minjae, Huang David T., Newman Anne B., Kong Lan, Kellum John A., Harris Tamara B., Bauer Doug, Satterfield Suzanne, Angus Derek C. The influence of pre-existing diabetes mellitus on the host immune response and outcome of pneumonia: analysis of two multicentre cohort studies Thorax 2010;65 (10):870-877 [PubMed]
  • Schouten Marcel, van 't Veer Cornelis, van den Boogaard Florry E., Gerlitz Bruce, Grinnell Brian W., Roelofs Joris J. T. H., Levi Marcel, van der Poll Tom Therapeutic recombinant murine activated protein C attenuates pulmonary coagulopathy and improves survival in murine pneumococcal pneumonia Journal of infectious diseases 2010;202 (10):1600-1607 [PubMed]
  • van der Windt Gerritje J. W. The role of CD44 and osteopontin in infection and imflammation 2010. 224p. ISBN 9789090251981. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: de Vos A. F.)
  • de Jong Hanna Katrien, van der Poll Tom, Wiersinga Willem Joost The Systemic Pro-Inflammatory Response in Sepsis Journal of innate immunity 2010;2 (5):422-430 [PubMed]
  • Pulskens Wilco P., Rampanelli Elena, Teske Gwendoline J., Butter Loes M., Claessen Nike, Luirink Ilse K., Poll Tom van der, Florquin Sandrine, Leemans Jaklien C. TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury Journal of the American Society of Nephrology 2010;21 (8):1299-1308 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, van der Poll Tom Toll-like receptor 9 is not important for host defense against Haemophilus influenzae Immunobiology 2010;215 (11):910-914 [PubMed]
  • Bezemer Daniela, van Sighem Ard, Lukashov Vladimir V., van der Hoek Lia, Back Nicole, Schuurman Rob, Boucher Charles A. B., Claas Eric C. J., Boerlijst Maarten C., Coutinho Roel A., de Wolf Frank, Prins J. M., Bos J. C., Eeftinck-Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., Olszyna D. P., van der Poll T., Reiss P., Sankatsing S. U. C., Steingrover R., van der Valk M., Vermeulen J. N., Vrouenraets S. M. E., van Vugt M., Schrei G., van der Geest S., Oude Lashof A., Lowe S., Verbon A., Bravenboer B., Pronk M. J. H., Kuijpers T. W., Pajkrt D., Scherpbier H. J., van der Ende M. E., Bax H., van der Feltz M., Gelinck L. B. S., de Melo Mendoca, Nouwen J. L., Rijnders B. J. A., de Ruiter E. D., Zaaijer H. L., Berkhout B., Jurriaans S., van Kan H. J. M. Transmission networks of HIV-1 among men having sex with men in the Netherlands AIDS (London, England) 2010;24 (2):271-282 [PubMed]
  • Levi M. [=Marcel M.], van der Poll Tom Update on physiological anticoagulant factor concentrates in patients with sepsis Yearbook of intensive care and emergency medicine 2010;2010:297-309
  • Wiersinga W. Joost, Kager Liesbeth M., Hovius Joppe W. R., van der Windt Gerritje J. W., de Vos Alex F., Meijers Joost C. M., Roelofs Joris J., Dondorp Arjen, Levi Marcel, Day Nicholas P., Peacock Sharon J., van der Poll Tom Urokinase Receptor Is Necessary for Bacterial Defense against Pneumonia-Derived Septic Melioidosis by Facilitating Phagocytosis Journal of immunology (Baltimore, Md. 2010;184 (6):3079-3086 [PubMed]

2009

  • Hoogerwerf Jacobien J., de Vos Alex F., Levi Marcel, Bresser Paul, van der Zee Jaring S., Draing Christian, von Aulock Sonja, van der Poll Tom Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide Critical care medicine 2009;37 (2):619-625 [PubMed]
  • Schultz Marcus J., Juffermans Nicole P., van der Poll Tom A new twist on the legend of granulocyte colony-stimulating factor in acute lung injury? Critical care medicine 2009;37 (4):1506-1507 [PubMed]
  • Vergouwen Mervyn D. I., Meijers Joost C. M., Geskus Ronald B., Coert Bert A., Horn Janneke, Stroes Erik S. G., van der Poll Tom, Vermeulen Marinus, Roos Yvo B. W. E. M. Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled randomized trial Journal of cerebral blood flow and metabolism 2009;29 (8):1444-1453 [PubMed]
  • Wiersinga W. Joost, van der Poll Tom Burkholderia pseudomallei Tropism and the Melioidosis Road Map Journal of infectious diseases 2009;199 (12):1720-1722 [PubMed]
  • Leendertse Masja, Willems Rob J., Giebelen Ida A., Florquin Sandrine, van den Pangaart Petra S., Bonten Marc J., van der Poll Tom Cecal ligation and puncture induced sepsis impairs host defense against Enterococcus faecium peritonitis Intensive care medicine 2009;35 (5):924-932 [PubMed]
  • Schouten Marcel, Van Der Poll Tom Coagulation disorders in sepsisin: Management of Sepsis. Springer Berlin Heidelberg; 2009. p. 131-146, ISBN 9783642004780
  • Yende Sachin, van der Poll Tom Diabetes and sepsis outcomes - it is not all bad news Critical care (London, England) 2009;13 (1):117 [PubMed]
  • Schouten M., van de Pol M. A., Levi M. [=Marcel M.], van der Poll T., van der Zee J. S. Early activation of coagulation after allergen challenge in patients with allergic asthma Journal of thrombosis and haemostasis 2009;7 (9):1592-1594 [PubMed]
  • van der Crabben Saskia N., Blümer Regje M. E., Stegenga Michiel E., Ackermans Mariëtte T., Endert Erik, Tanck Michael W. T., Serlie Mireille J., van der Poll Tom, Sauerwein Hans P. Early endotoxemia increases peripheral and hepatic insulin sensitivity in healthy humans Journal of clinical endocrinology and metabolism 2009;94 (2):463-468 [PubMed]
  • Roelofs Joris J. T. H., Rouschop Kasper M. A., Teske Gwendoline J. D., Wagenaar Gerry T. M., Claessen Nike, Weening Jan J., van der Poll Tom, Florquin Sandrine Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection Nephrology, dialysis, transplantation 2009;24 (3):801-808 [PubMed]
  • Heikens Esther, Leendertse Masja, Wijnands Lucas M., van Luit-Asbroek Miranda, Bonten Marc J. M., van der Poll Tom, Willems Rob J. L. Enterococcal surface protein Esp is not essential for cell adhesion and intestinal colonization of Enterococcus faecium in mice BMC microbiology 2009;9 (1):19 [PubMed]
  • Leendertse Masja, Heikens Esther, Wijnands Lucas M., van Luit-Asbroek Miranda, Teske Gwendoline J. D., Roelofs Joris J. T. H., Bonten Marc J. M., van der Poll Tom, Willems Rob J. L. Enterococcal surface protein transiently aggravates Enterococcus faecium-induced urinary tract infection in mice Journal of infectious diseases 2009;200 (7):1162-1165 [PubMed]
  • Leendertse Masja Enterococcus faecium infections: where bacterial virulence meets innate immunity 2009. 235p. ISBN 9789490122201. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Bonten M. J. M.; Co-supervisor: Willems R. J. L.)
  • van Zoelen Marieke A. D., Vogl Thomas, Foell Dirk, van Veen Suzanne Q., van Till Jan W. O., Florquin Sandrine, Tanck Michael W., Wittebole Xavier, Laterre Pierre-François, Boermeester Marja A., Roth Johannes, van der Poll Tom Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis American journal of respiratory and critical care medicine 2009;180 (11):1098-1106 [PubMed]
  • Dessing Mark C., van der Sluijs Koenraad F., Spek C. Arnold, van der Poll Tom Gene expression profiles in murine influenza pneumonia Journal of innate immunity 2009;1 (4):366-375 [PubMed]
  • Brouwer Matthijs C., de Gans Jan, Heckenberg Sebastiaan G. B., Zwinderman Aeilko H., van der Poll Tom, van de Beek Diederik Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis Lancet infectious diseases 2009;9 (1):31-44 [PubMed]
  • Wiersinga Willem J., van der Poll Tom Immunity to Burkholderia pseudomallei Current opinion in infectious diseases 2009;22 (2):102-108 [PubMed]
  • Wiersinga Willem Joost, van't Veer Cornelis, van den Pangaart Petra S., Dondorp Arjen M., Day Nicholas P., Peacock Sharon J., van der Poll Tom Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis) Critical care medicine 2009;37 (2):569-576 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., Roelofs Joris J. T. H., Top Janetta, Bonten Marc J. M., van der Poll Tom Intestinal Colonization with Enterococcus faecium Does Not Influence Pulmonary Defense against Pseudomonas aeruginosa in Mice PLoS ONE 2009;4 (8):e6775 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Oei G. Anneke, Florquin Sandrine, Bonten Marc J. M., van der Poll Tom Intestinal Enterococcus faecium Colonization Improves Host Defense during Polymicrobial Peritonitis Journal of infectious diseases 2009;200 (5):735-744 [PubMed]
  • de Vos Alex F., Pater Jennie M., van den Pangaart Petra S., de Kruif Martijn D., van 't Veer Cornelis, van der Poll Tom In Vivo Lipopolysaccharide Exposure of Human Blood Leukocytes Induces Cross-Tolerance to Multiple TLR Ligands Journal of immunology (Baltimore, Md. 2009;183 (1):533-542 [PubMed]
  • Hofstra Jorrit J., Cornet Alexander D., de Rooy Bart F., Vlaar Alexander P., van der Poll Tom, Levi Marcel, Zaat Sebastian A. J., Schultz Marcus J. Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats Critical care (London, England) 2009;13 (5):R145 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., Roelofs Joris J. T. H., Bonten Marc J. M., van der Poll Tom Neutrophils Are Essential for Rapid Clearance of Enterococcus faecium in Mice Infection and immunity 2009;77 (1):485-491 [PubMed]
  • van der Windt Gerritje J. W., Wieland Catharina W., Wiersinga Willem J., Florquin Sandrine, van der Poll Tom Osteopontin is not crucial to protective immunity during murine tuberculosis Immunology 2009;128 (1 Suppl):e766-e776 [PubMed]
  • van der Poll Tom, Opal Steven M. Pathogenesis, treatment, and prevention of pneumococcal pneumonia Lancet 2009;374 (9700):1543-1556 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., Roelofs Joris J. T. H., van Rooijen Nico, Bonten Marc J. M., van der Poll Tom Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice Innate immunity 2009;15 (1):3-12 [PubMed]
  • Roelofs Joris J. T. H., Teske Gwendoline J. D., Bonta Peter I., de Vries Carlie J. M., Meijers Joost C. M., Weening Jan J., van der Poll Tom, Florquin Sandrine Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis Kidney international 2009;75 (1):52-59 [PubMed]
  • de Jager C. P. C., de Wit N. C. J., Weers-Pothoff G., van der Poll T., Wever P. C. Procalcitonin kinetics in Legionella pneumophila pneumonia Clinical microbiology and infection 2009;15 (11):1020-1025 [PubMed]
  • van Zoelen Marieke A. D. RAGE and the innate immune response in infection and inflammation 2009. 296p. ISBN 9789064643491. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.)
  • van Zoelen Marieke A. D., Schmidt Ann-Marie, Florquin Sandrine, Meijers Joost C., de Beer Regina, de Vos Alex F., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom Receptor for Advanced Glycation End Products Facilitates Host Defense during Escherichia coli-Induced Abdominal Sepsis in Mice Journal of infectious diseases 2009;200 (5):765-773 [PubMed]
  • van Zoelen Marieke A. D., van der Sluijs Koenraad F., Achouiti Achmed, Florquin Sandrine, Braun-Pater Jennie M., Yang Huan, Nawroth Peter P., Tracey Kevin J., Bierhaus Angelika, van der Poll Tom Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia Virology 2009;391 (2):265-273 [PubMed]
  • Wolthuis Esther K., Vlaar Alexander P. J., Choi Goda, Roelofs Joris J. T. H., Haitsma Jack J., van der Poll Tom, Juffermans Nicole P., Zweers Machteld M., Schultz Marcus J. Recombinant human soluble tumor necrosis factor-alpha receptor fusion protein partly attenuates ventilator-induced lung injury Shock (Augusta, Ga.) 2009;31 (3):262-266 [PubMed]
  • Kesselring Anouk M., Wit Ferdinand W., Sabin Caroline A., Lundgren Jens D., Gill M. John, Gatell Jose M., Rauch Andri, Montaner Julio S., de Wolf Frank, Reiss Peter, Mocroft Amanda, Bronsveld W., Hillebrand-Haverkort M. E., Prins J. M., Bos J. C., Eeftinck Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van Leth F. C., Lowe S. H., van der Meer J. T. M., Nellen F. J. B., Pogány K., van der Poll T., Ruys T. A., Sankatsing Raaj R., Steingrover R., vanTwillert G., van der Valk M., van Vonderen M. G. A., Vrouenraets S. M. E., van Vugt M., van Eeden A., ten Veen J. H., van Dam P. S., Roos J. C., Brinkman K., Frissen P. H. J., Weigel H. M., Mulder J. W., van Gorp E. C. M., Meenhorst P. L., Mairuhu A. T. A., Veenstra J., Danner S. A., van Agtmael M. A., Claessen F. A. P., Perenboom R. M., Rijkeboer A. Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy AIDS (London, England) 2009;23 (13):1689-1699 [PubMed]
  • van Zoelen Marieke A. D., Yang Huan, Florquin Sandrine, Meijers Joost C. M., Akira Shizuo, Arnold Bernd, Nawroth Peter P., Bierhaus Angelika, Tracey Kevin J., van der Poll Tom Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo Shock (Augusta, Ga.) 2009;31 (3):280-284 [PubMed]
  • Dessing Mark C., Hirst Robert A., de Vos Alex F., van der Poll Tom Role of Toll-Like Receptors 2 and 4 in Pulmonary Inflammation and Injury Induced by Pneumolysin in Mice PLoS ONE 2009;4 (11):e7993 [PubMed]
  • Wagenaar Jiri F. P., Gasem M. Hussein, Goris Marga G. A., Leeflang Mariska, Hartskeerl Rudy A., van der Poll Tom, van 't Veer Cornelis, van Gorp Eric C. M. Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis PLoS neglected tropical diseases 2009;3 (6):e453 [PubMed]
  • Wieland Catharina W., van der Windt Gerritje J. W., Florquin Sandrine, McKenzie Andrew N. J., van der Poll Tom ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis Microbes and infection / Institut Pasteur 2009;11 (4):524-530 [PubMed]
  • Giebelen I. A. J., Leendertse M., Florquin S., van der Poll T. Stimulation of acetylcholine receptors impairs host defence during pneumococcal pneumonia European respiratory journal 2009;33 (2):375-381 [PubMed]
  • van Maanen Marjolein A., Lebre Maria C., van der Poll Tom, Larosa Gregory J., Elbaum Daniel, Vervoordeldonk Margriet J., Tak Paul P. Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice Arthritis and rheumatism 2009;60 (1):114-122 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., van den Pangaart Petra S., Bonten Marc J. M., van der Poll Tom The acute-phase response impairs host defence against Enterococcus faecium peritonitis Immunology 2009;128 (1 Suppl):e335-e342 [PubMed]
  • van Zoelen Marieke A. D., Schouten Marcel, de Vos Alex F., Florquin Sandrine, Meijers Joost C. M., Nawroth Peter P., Bierhaus Angelika, van der Poll Tom The Receptor for Advanced Glycation End Products Impairs Host Defense in Pneumococcal Pneumonia Journal of immunology (Baltimore, Md. 2009;182 (7):4349-4356 [PubMed]
  • Leemans Jaklien C., Butter Loes M., Pulskens Wilco P. C., Teske Gwendoline J. D., Claessen Nike, van der Poll Tom, Florquin Sandrine The Role of Toll-Like Receptor 2 in Inflammation and Fibrosis during Progressive Renal Injury PLoS ONE 2009;4 (5):e5704 [PubMed]
  • Stegenga Michiel E., Florquin Sandrine, de Vos Alex F., van der Poll Tom The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice Critical care medicine 2009;37 (2):614-618 [PubMed]
  • Hovius Joppe W. R., Bijlsma Maarten F., van der Windt Gerritje J. W., Wiersinga W. Joost, Boukens Bastiaan J. D., Coumou Jeroen, Oei Anneke, de Beer Regina, de Vos Alex F., van 't Veer Cornelis, van Dam Alje P., Wang Penghua, Fikrig Erol, Levi Marcel M., Roelofs Joris J. T. H., van der Poll Tom The Urokinase Receptor (uPAR) Facilitates Clearance of Borrelia burgdorferi PLoS pathogens 2009;5 (5):e1000447 [PubMed]
  • Hovius Joppe W. R. Tick-host-pathogen interactions in Lyme borreliosis 2009. 270p. ISBN 9789064643224. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Speelman P.; Co-supervisors: van Dam A. P., Fikrig E.)
  • van Zoelen Marieke A. D., Florquin Sandrine, de Beer Regina, Pater Jennie M., Verstege Marleen I., Meijers Joost C. M., van der Poll Tom Urokinase Plasminogen Activator Receptor-Deficient Mice Demonstrate Reduced Hyperoxia-Induced Lung Injury American journal of pathology 2009;174 (6):2182-2189 [PubMed]
  • Mocroft Amanda, Sterne Jonathan A. C., Egger Matthias, May Margaret, Grabar Sophie, Furrer Hansjakob, Sabin Caroline, Fatkenheuer Gerd, Justice Amy, Reiss Peter, D'Arminio Monforte Antonella, Gill John, Hogg Robert, Bonnet Fabrice, Kitahata Mari, Staszewski Schlomo, Casabona Jordi, Harris Ross, Saag Michael, Chêne Geneviève, Costagliola Dominique, Dabis François, de Wolf Frank, Ledergerber Bruno, Phillips Andrew, Weller Ian, Sterne Jonathan, Abgrall S., Barin F., Bentata M., Billaud E., Boué F., Gras L. A., Prins J. M., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Vermeulen J. N., van Vugt M., Wit F. W. M. N., Kuijpers T. W., Pajkrt D., Scherpbier H. J., Back N. K. T., Berkhout B., Jurriaans S., Zaaijer H. L., van Kan H. J. M. Variable impact on mortality of AIDS-defining events diagnosed during combination antiretroviral therapy: not all AIDS-defining conditions are created equal Clinical infectious diseases 2009;48 (8):1138-1151 [PubMed]
  • Gras Luuk, Jurriaans Suzanne, Bakker Margreet, van Sighem Ard, Bezemer Daniela, Fraser Christophe, Lange Joep, Prins Jan M., Berkhout Ben, de Wolf Frank, Bos J. C., Eeftinck-Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., van der Meer J. T. M., Nellen F. J. B., Olszyna D. P., van der Poll T., Reiss P., Sankatsing S. U. C., Steingrover R., van der Valk M., Vermeulen J. N., Vrouenraets S. M. E., van Vugt M., Wit F. W. M. N., Schreij G., van der Geest S. Viral load levels measured at set-point have risen over the last decade of the HIV epidemic in the Netherlands PLoS ONE 2009;4 (10):e7365 [PubMed]

2008

  • Wiersinga W. J., Meijers J. C. M., Levi M. [=Marcel M.], van 't Veer C., Day N. P., Peacock S. J., van der Poll T. Activation of coagulation with concurrent impairment of anticoagulant mechanisms correlates with a poor outcome in severe melioidosis Journal of thrombosis and haemostasis 2008;6 (1):32-39 [PubMed]
  • Renckens Rosemarijn, van Westerloo David J., Roelofs Joris J. T. H., Pater Jennie M., Schultz Marcus J., Florquin Sandrine, van der Poll Tom Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice Critical care medicine 2008;36 (2):580-587 [PubMed]
  • Veninga Henrike, Becker Susann, Hoek Robert M., Wobus Manja, Wandel Elke, van der Kaa Jos, van der Valk Martin, de Vos Alex F., Haase Hannelore, Owens Bronwyn, van der Poll Tom, van Lier René A. W., Verbeek J. Sjef, Aust Gabriela, Hamann Jörg Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration Journal of immunology (Baltimore, Md. 2008;181 (9):6574-6583 [PubMed]
  • Choi Goda, Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., Rijneveld Anita W., Bresser Paul, van der Zee Jaring S., Florquin Sandrine, van der Poll Tom, Levi Marcel, Schultz Marcus J. Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats Critical care medicine 2008;36 (1):204-210 [PubMed]
  • Hardenberg Gijs, van der Sluijs Koen, van der Poll Tom, Medema Jan Paul APRIL affects antibody responses and early leukocyte infiltration, but not influenza A viral control Molecular immunology 2008;45 (11):3050-3058 [PubMed]
  • Wieland Catharina W., van der Windt Gerritje J. W., Wiersinga W. Joost, Florquin Sandrine, van der Poll Tom CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis Immunology 2008;125 (2):272-279 [PubMed]
  • Wiersinga W. Joost, de Vos Alex F., Wieland Catharina W., Leendertse Masja, Roelofs Joris J. T. H., van der Poll Tom CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice Journal of infectious diseases 2008;198 (9):1388-1397 [PubMed]
  • Sabin C. A., d'Arminio Monforte A., Friis-Moller N., Weber R., El-Sadr W. M., Reiss P., Kirk O., Mercie P., Law M. G., de Wit S., Pradier C., Phillips A. N., Lundgren J. D., Collins S., Loeliger E., Tressler R., Weller I., Friis-Møller N., Worm S. W., Sjøl A., Sawitz A., Rickenbach M., Pezzotti P., Krum E., Gras L., Balestre E., Sundström A., Poll B., Fontas E., Torres F., Petoumenos K., Kjaer J., de Wolf F., Zaheri S., Bronsveld W., Hillebrand-Haverkort M. E., Prins J. M., Bos J. C., Eeftinck Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van Leth F. C., Lowe S. H., van der Meer J. T. M., Nellen F. J. B., van der Poll T., van der Valk M., van Vugt M., Wit F. W. M. N. Changes over time in risk factors for cardiovascular disease and use of lipid-lowering drugs in HIV-infected individuals and impact on myocardial infarction Clinical infectious diseases 2008;46 (7):1101-1110 [PubMed]
  • Giebelen Ilona A. J., Le Moine Alain, van den Pangaart Petra S., Sadis Claude, Goldman Michel, Florquin Sandrine, van der Poll Tom Deficiency of alpha7 cholinergic receptors facilitates bacterial clearance in Escherichia coli peritonitis Journal of infectious diseases 2008;198 (5):750-757 [PubMed]
  • Lemaire Lucienne C., de Kruif Martijn D., Giebelen Ida A., van Zoelen Marieke A. D., Veer Cornelis Van't, van der Poll Tom Differential dose-dependent effects of prednisolone on shedding of endothelial adhesion molecules during human endotoxemia Immunology letters 2008;121 (2):93-96 [PubMed]
  • Mugavero Michael J., May Margaret, Harris Ross, Saag Michael S., Costagliola Dominique, Egger Matthias, Phillips Andrew, Günthard Huldrych F., Dabis Francois, Hogg Robert, de Wolf Frank, Fatkenheuer Gerd, Gill M. John, Justice Amy, D'Arminio Monforte Antonella, Lampe Fiona, Miró Jose M., Staszewski Schlomo, Sterne Jonathan A. C., Casabona Jordi, Geneviè Chêne, Dabis François, del Amo Julia, Fätkenheuer Gerd, Gill John, Guest Jodie, Kitahata Mari, Ledergerber Bruno, Mocroft Amanda, Reiss Peter, Saag Michael, Sterne Jonathan, Gras L. A., Prins J. M., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Vermeulen J. N., van Vugt M., Wit F. W. M. N., Kuijpers T. W., Pajkrt D., Scherpbier H. J., Back N. K. T., Berkhout B., Jurriaans S., Zaaijer H. L., van Kan H. J. M. Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice? AIDS (London, England) 2008;22 (18):2481-2492 [PubMed]
  • Stegenga M. E., van der Crabben S. N., Dessing M. C., Pater J. M., van den Pangaart P. S., de Vos A. F., Tanck M. W., Roos D., Sauerwein H. P., van der Poll T. Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans Diabetic medicine 2008;25 (2):157-164 [PubMed]
  • de Kruif Martijn D., Lemaire Lucienne C., Giebelen Ida A., Groot Angelique P., Pater Jennie M., van den Pangaart Petra S., Elliott Peter J., van der Poll Tom Effects of prednisolone on the systemic release of mediators of cell-mediated cytotoxicity during human endotoxemia Shock (Augusta, Ga.) 2008;29 (4):458-461 [PubMed]
  • Giebelen Ida A. J., Leendertse Masia, Dessing Mark C., Meijers Joost C. M., Levi Marcel, Draing Christian, von Aulock Sonja, van der Poll Tom Endogenous beta-adrenergic receptors inhibit lipopolysaccharide-induced pulmonary cytokine release and coagulation American journal of respiratory cell and molecular biology 2008;39 (3):373-379 [PubMed]
  • Wiersinga W. Joost, Dessing Mark C., van der Poll Tom Gene-expression profiles in murine melioidosis Microbes and infection / Institut Pasteur 2008;10 (8):868-877 [PubMed]
  • van der Crabben Saskia N. Glucose deregulation in health and disease: on inflammation and glutathione 2008. 128p. ISBN 9789090233574. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Sauerwein H. P., van der Poll T.; Co-supervisors: Serlie M. J., Ackermans M. T.)
  • Levi Marcel, Van Der Poll Tom Hemostasis and coagulationin: Surgery. Springer New York; 2008. p. 149-165, ISBN 9783540297338
  • D'Arminio Monforte Antonella, Abrams Donald, Pradier Christian, Weber Rainer, Reiss Peter, Bonnet Fabrice, Kirk Ole, Law Matthew, de Wit Stephane, Friis-Møller Nina, Phillips Andrew N., Sabin Caroline A., Lundgren Jens D., Collins S., Loeliger E., Tressler R., Weller I., Friis-Møller N., Worm S. W., Sabin C. A., Sjøl A., Lundgren J. D., Sawitz A., Rickenbach M., Pezzotti P., Krum E., Gras L., Balestre E., Sundström A., Poll B., Fontas E., Torres F., Petoumenos K., Kjaer J., de Wolf F., Zaheri S., Bronsveld W., Hillebrand-Haverkort M. E., Prins J. M., Bos J. C., Eeftinck Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., van der Valk M., van Vugt M., Wit F. W. M. N. HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignancies AIDS (London, England) 2008;22 (16):2143-2153 [PubMed]
  • van der Poll Tom, Opal Steven M. Host-pathogen interactions in sepsis Lancet infectious diseases 2008;8 (1):32-43 [PubMed]
  • Stegenga Michiel E., van der Crabben Saskia N., Blümer Regje M. E., Levi Marcel, Meijers Joost C. M., Serlie Mireille J., Tanck Michael W. T., Sauerwein Hans P., van der Poll Tom Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia Blood 2008;112 (1):82-89 [PubMed]
  • Blümer Regje M. E., van der Crabben Saskia N., Stegenga Michiel E., Tanck Michael W., Ackermans Mariette T., Endert Erik, van der Poll Tom, Sauerwein Hans P. Hyperglycemia prevents the suppressive effect of hyperinsulinemia on plasma adiponectin levels in healthy humans American journal of physiology. Endocrinology and metabolism 2008;295 (3):E613-E617 [PubMed]
  • Schouten Marcel, Wiersinga Willem Joost, Levi Marcel, van der Poll Tom Inflammation, endothelium, and coagulation in sepsis Journal of leukocyte biology 2008;83 (3):536-545 [PubMed]
  • Wiersinga W. Joost, de Vos Alex F., de Beer Regina, Wieland Catharina W., Roelofs Joris J. T. H., Woods Donald E., van der Poll Tom Inflammation patterns induced by different Burkholderia species in mice Cellular microbiology 2008;10 (1):81-87 [PubMed]
  • van't Veer Cornelis, van der Poll Tom Keeping blood clots at bay in sepsis Nature medicine 2008;14 (6):606-608 [PubMed]
  • Knapp Sylvia, von Aulock Sonja, Leendertse Masja, Haslinger Isabella, Draing Christian, Golenbock Douglas T., van der Poll Tom Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor Journal of immunology (Baltimore, Md. 2008;180 (5):3478-3484 [PubMed]
  • Hoogerwerf Jacobien J., de Vos Alex F., Bresser Paul, van der Zee Jaring S., Pater Jennie M., de Boer Anita, Tanck Michael, Lundell Daniel L., Her-Jenh Chung, Draing Christian, von Aulock Sonja, van der Poll Tom Lung inflammation induced by lipoteichoic acid or lipopolysaccharide in humans American journal of respiratory and critical care medicine 2008;178 (1):34-41 [PubMed]
  • Wolthuis Esther K., Choi Goda, Dessing Mark C., Bresser Paul, Lutter Rene, Dzoljic Misa, van der Poll Tom, Vroom Margreeth B., Hollmann Markus, Schultz Marcus J. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury Anesthesiology 2008;108 (1):46-54 [PubMed]
  • Levi Marcel, Nieuwdorp Max, Poll Tom van der, Stroes Erik Metabolic modulation of inflammation-induced activation of coagulation Seminars in thrombosis and hemostasis 2008;34 (1):26-32 [PubMed]
  • Wiersinga W. Joost, Wieland Catharina W., Roelofs Joris J. T. H., van der Poll Tom MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei PLoS ONE 2008;3 (10):e3494 [PubMed]
  • Wiersinga W. J. On Toll-like receptors and the innate immune response in sepsis caused by Burkholderia pseudomallei (melioidosis) 2008. 295p. ISBN 9789064642890. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.; Co-supervisor: Peacock S. J.)
  • van Zoelen Marieke A. D., Florquin Sandrine, Meijers Joost C. M., de Beer Regina, de Vos Alex F., de Boer Onno J., van der Poll Tom Platelet-activating factor receptor contributes to host defense against Pseudomonas aeruginosa pneumonia but is not essential for the accompanying inflammatory and procoagulant response Journal of immunology (Baltimore, Md. 2008;180 (5):3357-3365 [PubMed]
  • van Westerloo David J., Rauws Erik A., Hommes Daan, de Vos Alex F., van der Poll Tom, Powers Barbara L., Fockens Paul, Dijkgraaf Marcel G. W., Bruno Marco J. Pre-ERCP infusion of semapimod, a mitogen-activated protein kinases inhibitor, lowers post-ERCP hyperamylasemia but not pancreatitis incidence Gastrointestinal endoscopy 2008;68 (2):246-254 [PubMed]
  • Hovius J. W., Schuijt T. J., de Groot K. A., Roelofs J. J. T. H., Oei G. A., Marquart J. A., de Beer R., van 't Veer C., van der Poll T., Ramamoorthi N., Fikrig E., van Dam A. P. Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva Journal of infectious diseases 2008;198 (8):1189-1197 [PubMed]
  • van Zoelen Marieke A. D., Ishizaka Akitoshi, Wolthuls Esther K., Choi Goda, van der Poll Tom, Schultz Marcus J. Pulmonary levels of high-mobility group box 1 during mechanical ventilation and ventilator-associated pneumonia Shock (Augusta, Ga.) 2008;29 (4):441-445 [PubMed]
  • Dessing Mark C., Schouten Marcel, Draing Christian, Levi Marcel, von Aulock Sonja, van der Poll Tom Role played by Toll-like receptors 2 and 4 in lipoteichoic acid-induced lung inflammation and coagulation Journal of infectious diseases 2008;197 (2):245-252 [PubMed]
  • Hovius Joppe W. R., de Jong Marein A. W. P., den Dunnen Jeroen, Litjens Manja, Fikrig Erol, van der Poll Tom, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization PLoS pathogens 2008;4 (2):e31 [PubMed]
  • Levi Marcel, Schouten Marcel, van der Poll Tom Sepsis, coagulation, and antithrombin: old lessons and new insights Seminars in thrombosis and hemostasis 2008;34 (8):742-746 [PubMed]
  • Van Der Poll Tom SYM IX.2: Local activation of coagulation in severe infection Pathophysiology of haemostasis and thrombosis 2008;36 (SUPPL.):P109-P110
  • van Zoelen Marieke A. D., van der Poll Tom Targeting RAGE in sepsis Critical care (London, England) 2008;12 (1):103 [PubMed]
  • Giebelen Ida A. J. The effect of the central nervous system on infection and imflammation "It takes nerves" 2008. 199p. ISBN 9789064642005. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.)
  • de Kruif Martijn D., Lemaire Lucienne C., Giebelen Ida A., Struck Joachim, Morgenthaler Nils G., Papassotiriou Jana, Elliott Peter J., van der Poll Tom The influence of corticosteroids on the release of novel biomarkers in human endotoxemia Intensive care medicine 2008;34 (3):518-522 [PubMed]
  • Stegenga M. E. The influence of hyperglycemia and hyperinsulinemia on innate immune and coagulant responses 2008. 151p. ISBN 9789064642555. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Sauerwein H. P.)
  • Appelmelk B. J., den Dunnen J., Driessen N. N., Ummels R., Pak M., Nigou J., Larrouy-Maumus G., Gurcha S. S., Movahedzadeh F., Geurtsen J., Brown E. J., Eysink Smeets M. M., Besra G. S., Willemsen P. T. J., Lowary T. L., van Kooyk Y., Maaskant J. J., Stoker N. G., van der Ley P., Puzo G., Vandenbroucke-Grauls C. M. J. E., Wieland C. W., van der Poll T., Geijtenbeek T. B. H., van der Sar A. M., Bitter W. The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction Cellular microbiology 2008;10 (4):930-944 [PubMed]
  • Levi Marcel, van der Poll Tom The Role of Natural Anticoagulants in the Pathogenesis and Management of Systemic Activation of Coagulation and Inflammation in Critically Ill Patients Seminars in thrombosis and hemostasis 2008;34 (5):459-468 [PubMed]
  • van der Poll Tom Tissue factor as an initiator of coagulation and inflammation in the lung Critical care (London, England) 2008;12 (Suppl. 6):S3 [PubMed]
  • Leendertse Masja, Willems Rob J. L., Giebelen Ida A. J., van den Pangaart Petra S., Wiersinga W. Joost, de Vos Alex F., Florquin Sandrine, Bonten Marc J. M., van der Poll Tom TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis Journal of immunology (Baltimore, Md. 2008;180 (7):4865-4874 [PubMed]
  • Dessing Mark C., Florquin Sandrine, Paton James C., van der Poll Tom Toll-like receptor 2 contributes to antibacterial defence against pneumolysin-deficient pneumococci Cellular microbiology 2008;10 (1):237-246 [PubMed]
  • Pulskens Wilco P., Teske Gwendoline J., Butter Loes M., Roelofs Joris J., van der Poll Tom, Florquin Sandrine, Leemans Jaklien C. Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury PLoS ONE 2008;3 (10):e3596 [PubMed]
  • Renckens R., Roelofs J. J. T. H., Stegenga M. E., Florquin S., Levi M. [=Marcel M.], Carmeliet P., van't Veer C., van der Poll T. Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia Journal of thrombosis and haemostasis 2008;6 (4):660-668 [PubMed]
  • Sabin Caroline A., Worm Signe W., Weber Rainer, Reiss Peter, El-Sadr Wafaa, Dabis Francois, de Wit Stephane, Law Matthew, D'Arminio Monforte Antonella, Friis-Møller Nina, Kirk Ole, Pradier Christian, Weller Ian, Phillips Andrew N., Lundgren Jens D., Collins S., Dabis F., d'Arminio Monforte A., de Wit S., El-Sadr W. M., Kirk O., Law M., Pradier C., Phillips A., Rosseau F., Storfer S. P., Weber I., Lundgren J. D., Worm S. W., Friis-øller N., Sabin C. A., Sjøl A., Sawitz A., Rickenbach M., Pezzotti P., Krum E., Gras L., Balestre E., Sundström A., Prins J. M., Bos J. C., Geerlings S. E., Godfried M. H., Lange J. M. A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., van der Valk M., van Vugt M., Wit F. W. M. N. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration Lancet 2008;371 (9622):1417-1426 [PubMed]

2007

  • van Well Gijs Th. J., Wieland Catharina W., Florquin Sandrine, Roord John J., van der Poll Tom, van Furth A. Marceline A new murine model to study the pathogenesis of tuberculous meningitis Journal of infectious diseases 2007;195 (5):694-697 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Polfliet Machteld M. J., van den Berg Timo K., Dijkstra Christine D., Roord John J., Hack C. Erik, van Furth A. Marceline C1 inhibitor treatment improves host defense in pneumococcal meningitis in rats and mice Journal of infectious diseases 2007;196 (1):115-123 [PubMed]
  • Dessing Mark C., Knapp Sylvia, Florquin Sandrine, de Vos Alex F., van der Poll Tom CD14 facilitates invasive respiratory tract infection by Streptococcus pneumoniae American journal of respiratory and critical care medicine 2007;175 (6):604-611 [PubMed]
  • Dessing Mark C., van der Sluijs Koenraad F., Florquin Sandrine, van der Poll Tom CD14 plays a limited role during influenza A virus infection in vivo Immunology letters 2007;113 (1):47-51 [PubMed]
  • Choi G., Levi M. [=Marcel M.], van der Poll T. Coagulation and fibrinolysis in sepsis and pulmonary inflammationin: M. J. Schultz, P. E. Spronk, editors. Immunology in Intensive Care Medicine. S.l.: Research Signpost; 2007. p. 29-42, ISBN 9788130800448
  • Wiersinga W. J., Levi M. [=Marcel M.], van der Poll T. Coagulation in Sepsisin: E. Abraham, M. Singer, editors. Mechanisms of sepsis induced organ dysfunction and recovery. S.l.: Springer; 2007. p. 273-285, ISBN 9783540301585; 9783540301578
  • Hovius Joppe W. R., Li Xin, Ramamoorthi Nandhini, van Dam Alje P., Barthold Stephen W., van der Poll Tom, Speelman Peter, Fikrig Erol Coinfection with Borrelia burgdorferi sensu stricto and Borrelia garinii alters the course of murine Lyme borreliosis FEMS immunology and medical microbiology 2007;49 (2):224-234 [PubMed]
  • Wiersinga W. Joost, Wieland Catharina W., van der Windt Gerritje J. W., de Boer Anita, Florquin Sandrine, Dondorp Arjen, Day Nicholas P., Peacock Sharon J., van der Poll Tom Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis Infection and immunity 2007;75 (8):3739-3746 [PubMed]
  • Wiersinga W. Joost, Veer Cees van T., Wieland Catharina W., Gibot Sebastien, Hooibrink Berend, Day Nicholas P., Peacock Sharon J., van der Poll Tom Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis Journal of infectious diseases 2007;196 (11):1707-1716 [PubMed]
  • Birjmohun Rakesh S., van Leuven Sander I., Levels Johannes H. M., van 't Veer Cornelis, Kuivenhoven Jan Albert, Meijers Joost C. M., Levi Marcel, Kastelein John J. P., van der Poll Tom, Stroes Erik S. G. High-density lipoprotein attenuates inflammation and coagulation response on endotoxin challenge in humans Arteriosclerosis, thrombosis, and vascular biology 2007;27 (5):1153-1158 [PubMed]
  • Wiersinga W. Joost, Dessing Mark C., Kager Piet A., Cheng Allen C., Limmathurotsakul Direk, Day Nicholas P., Dondorp Arjen M., van der Poll Tom, Peacock Sharon J. High-throughput mRNA profiling characterizes the expression of inflammatory molecules in sepsis caused by Burkholderia pseudomallei Infection and immunity 2007;75 (6):3074-3079 [PubMed]
  • Lemaire L. C., van der Poll T. Immunomodulatory effects of general anestheticsin: Jean-Louis Vincent, editors. Yearbook of intensive Care and Emergency Medicine 2007. S.l.: Springer-Verlag; 2007. p. 208-216
  • van 't Veer Cornelis, van den Pangaart Petra S., van Zoelen Marieke A. D., de Kruif Martijn, Birjmohun Rakesh S., Stroes Eric S., de Vos Alex F., van der Poll Tom Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model Journal of immunology (Baltimore, Md. 2007;179 (10):7110-7120 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, van der Poll Tom Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae Infection and immunity 2007;75 (10):5068-5072 [PubMed]
  • van Zoelen Marieke A. D., de Vos Alex F., Larosa Gregory J., Draing Christian, von Aulock Sonja, van der Poll Tom Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo Shock (Augusta, Ga.) 2007;28 (5):570-575 [PubMed]
  • Wiersinga Willem Joost, van der Poll Tom Is the septic response good or bad? Current infectious disease reports 2007;9 (5):366-373 [PubMed]
  • Giebelen Ida A. J., van Westerloo David J., Larosa Gregory J., de Vos Alex F., van der Poll Tom Local stimulation of alpha 7 cholinergic receptors inhibits LPS-induced TNF-alpha release in the mouse lung Shock (Augusta, Ga.) 2007;28 (6):700-703 [PubMed]
  • Wieland Catharina W., Koppel Estella A., den Dunnen Jeroen, Florquin Sandrine, McKenzie Andrew N. J., van Kooyk Yvette, van der Poll Tom, Geijtenbeek Teunis B. H. Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis Microbes and infection / Institut Pasteur 2007;9 (2):134-141 [PubMed]
  • Dessing Mark C., van der Sluijs Koenraad F., Florquin Sandrine, van der Poll Tom Monocyte chemoattractant protein 1 contributes to an adequate immune response in influenza pneumonia Clinical immunology (Orlando, Fla.) 2007;125 (3):328-336 [PubMed]
  • Vogl Thomas, Tenbrock Klaus, Ludwig Stephan, Leukert Nadja, Ehrhardt Christina, van Zoelen Marieke A. D., Nacken Wolfgang, Foell Dirk, van der Poll Tom, Sorg Clemens, Roth Johannes Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock Nature medicine 2007;13 (9):1042-1049 [PubMed]
  • Choi G., Vlaar A. P. J., Schouten M., van't Veer C., van der Poll T. Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation European respiratory journal 2007;30 (3):423-428 [PubMed]
  • Wittkowski Helmut, Sturrock Anne, van Zoelen Marieke A. D., Viemann Dorothee, van der Poll Tom, Hoidal John R., Roth Johannes, Foell Dirk Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome Critical care medicine 2007;35 (5):1369-1375 [PubMed]
  • Knapp Sylvia, Matt Ulrich, Leitinger Norbert, van der Poll Tom Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo Journal of immunology (Baltimore, Md. 2007;178 (2):993-1001 [PubMed]
  • Opal Steven M., van der Poll T. Pathophysiology of sepsisin: P. Dellinger, J. Carlet, editors. Sepsis handbook Early Diagnosis of Sepsis. S.l.: bioMérieux; 2007. p. 75-89
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Bonta Peter I., Florquin Sandrine, de Vries Carlie J. M., Levi Marcel, Carmeliet Peter, van't Veer Cornelis, van der Poll Tom Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia Blood 2007;109 (4):1593-1601 [PubMed]
  • de Kruif Martijn D., Lemaire Lucienne C., Giebelen Ida A., van Zoelen Marieke A. D., Pater Jennie M., van den Pangaart Petra S., Groot Angelique P., de Vos Alex F., Elliott Peter J., Meijers Joost C. M., Levi Marcel, van der Poll Tom Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia Journal of immunology (Baltimore, Md. 2007;178 (3):1845-1851 [PubMed]
  • Radosevic Katarina, Wieland Catharina W., Rodriguez Ariane, Weverling Gerrit Jan, Mintardjo Ratna, Gillissen Gert, Vogels Ronald, Skeiky Yasir A. W., Hone David M., Sadoff Jerald C., van der Poll Tom, Havenga Menzo, Goudsmit Jaap Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon Infection and immunity 2007;75 (8):4105-4115 [PubMed]
  • Levi Marcel, van der Poll Tom Recombinant human activated protein C: current insights into its mechanism of action Critical care (London, England) 2007;11 Suppl 5 (Suppl. 5):S3 [PubMed]
  • Choi Goda, Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., Florquin Sandrine, Bresser Paul, Levi Marcel, van der Poll Tom, Schultz Marcus J. Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats Critical care medicine 2007;35 (5):1362-1368 [PubMed]
  • de Fost M., Chierakul W., Limpaiboon R., Dondorp A., White N. J., van der Poll T. Release of granzymes and chemokines in Thai patients with leptospirosis Clinical microbiology and infection 2007;13 (4):433-436 [PubMed]
  • Maris Nico A., de Vos Alex F., Bresser Paul, van der Zee Jaring S., Jansen Henk M., Levi Marcel, van der Poll Tom Salmeterol enhances pulmonary fibrinolysis in healthy volunteers Critical care medicine 2007;35 (1):57-63 [PubMed]
  • Giebelen Ida A. J., van Westerloo David J., Larosa Gregory J., de Vos Alex F., van der Poll Tom Stimulation of alpha 7 cholinergic receptors inhibits lipopolysaccharide-induced neutrophil recruitment by a tumor necrosis factor alpha-independent mechanism Shock (Augusta, Ga.) 2007;27 (4):443-447 [PubMed]
  • van Zoelen Marieke A. D., Laterre Pierre-Francois, van Veen Suzanne Q., van Till Jan W. O., Wiffebole Xavier, Bresser Paul, Tanck Michael W., Dugernier Thierry, Ishizaka Akitoshi, Boermeester Marja A., van der Poll Tom Systemic and local high mobility group box 1 concentrations during severe infection Critical care medicine 2007;35 (12):2799-2804 [PubMed]
  • Renckens Rosemarijn The fibrinolytic system in infection & inflammation 2007. 203p. ISBN 9789090216454. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll Tom; Co-supervisor: van 't Veer Cornelis)
  • Hommes T. J., Wiersinga W. J., Van Der Poll T. The host response to sepsisin: Yearbook of Intensive Care and Emergency Medicine 2009. Springer New York; 2007. p. 39-50, ISBN 9780387922775
  • van Westerloo D. J. The inflammatory response in critical illness 2007. 211p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll Tom; Co-supervisors: Bruno M. J., de Vos Alex F.)
  • Jacobs J. W. G., Creemers M. C. W., van Agtmael M. A., van de Laar M. A. F. J., van der Poll T., Tak P. P., Bijlsma J. W. J. TNF-blokkerende geneesmiddelen en infecties; adviezen voor de dagelijkse praktijk Nederlands tijdschrift voor geneeskunde 2007;151 (10):588-593 [PubMed]
  • Dessing Mark C., van der Sluijs Koenraad F., Florquin Sandrine, Akira Shizuo, van der Poll Tom Toll-like receptor 2 does not contribute to host response during postinfluenza pneumococcal pneumonia American journal of respiratory cell and molecular biology 2007;36 (5):609-614 [PubMed]
  • Wiersinga W. Joost, Wieland Catharina W., Dessing Mark C., Chantratita Narisara, Cheng Allen C., Limmathurotsakul Direk, Chierakul Wirongrong, Leendertse Masja, Florquin Sandrine, de Vos Alex F., White Nicholas, Dondorp Arjen M., Day Nicholas P., Peacock Sharon J., van der Poll Tom Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis) PLoS medicine 2007;4 (7):1268-1280 [PubMed]
  • Dessing Mark C. Toll-like receptors and innate immunity in pneumonia 2007. 191p. ISBN 9789090218649. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll Tom; Co-supervisor: de Vos Alex F.)
  • Wiersinga W. J., van der Poll T. Toll-like receptors and sepsisin: M. J. Schultz, P. E. Spronk, editors. Immunology in Intensive Care Medicine. S.l.: Research Signpost; 2007. p. 75-89, ISBN 9788130800448

2006

  • Wieland Catharina W., Kerver Marjolein E., Florquin Sandrine, Nolte Martijn A., Borst Jannie, van Lier Rene, van Oers Marinus H. J., van der Poll Tom CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome International immunology 2006;18 (11):1531-1539 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, Pater Jennie M., Weijer Sebastiaan, van der Poll Tom CD4+ cells play a limited role in murine lung infection with Mycobacterium kansasii American journal of respiratory cell and molecular biology 2006;34 (2):167-173 [PubMed]
  • Van Der Poll Tom, Schultz Marcus J. Cellular and molecular aspects of pneumoniain: Principles of Molecular Medicine. Humana Press; 2006. p. 912-919, ISBN 9781588292025
  • Zwijnenburg Petra J. G., van der Poll Tom, Roord John J., van Furth A. Marceline Chemotactic factors in cerebrospinal fluid during bacterial meningitis Infection and immunity 2006;74 (3):1445-1451 [PubMed]
  • Klazinga N., Prins M. [= Maria], Verhoeff A., Stronks K., van der Poll T. De academische werkkplaats GGD/AMC in Amsterdam Tijdschrift voor gezondheidswetenschappen (TSG) 2006;84 (4):199-200
  • Knapp Sylvia, Wieland Catharina W., Florquin Sandrine, Pantophlet Ralph, Dijkshoorn Lenie, Tshimbalanga Ntambua, Akira Shizuo, van der Poll Tom Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia American journal of respiratory and critical care medicine 2006;173 (1):122-129 [PubMed]
  • Lemaire Lucienne C., de Kruif Martijn D., Giebelen Ida A., Levi Marcel, van der Poll Tom, Heesen Michael Dobutamine does not influence inflammatory pathways during human endotoxemia Critical care medicine 2006;34 (5):1365-1371 [PubMed]
  • Keller Tymen T., van der Sluijs Koen F., de Kruif Martijn D., Gerdes Victor E. A., Meijers Joost C. M., Florquin Sandrine, van der Poll Tom, van Gorp Eric C. M., Brandjes Dees P. M., Büller Harry R., Levi Marcel Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1 Circulation research 2006;99 (11):1261-1269 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Lijnen H. Roger, Carmeliet Peter, van 't Veer Cornelis, van der Poll Tom Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice Journal of immunology (Baltimore, Md. 2006;177 (2):1189-1196 [PubMed]
  • van Zoelen Marieke A. D., Bakhtiari Kamran, Dessing Mark C., van't Veer Cornelis, Spek C. Arnold, Tanck Michael, Meijers Joost C., van der Poll Tom Ethyl pyruvate exerts combined anti-inflammatory and anticoagulant effects on human monocytic cells Thrombosis and haemostasis 2006;96 (6):789-793 [PubMed]
  • Wieland C. W. Host-pathogen interactions duri ng (myco)bacterial respiratory tract infections 2006. 256p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.)
  • Heesen Michael, Renckens Rosemarijn, de Vos Alex F., Kunz Dagmar, van der Poll Tom Human endotoxemia induces down-regulation of monocyte CC chemokine receptor 2 Clinical and vaccine immunology 2006;13 (1):156-159 [PubMed]
  • Stegenga Michiel E., van der Crabben Saskia N., Levi Marcel, de Vos Alex F., Tanck Michael W., Sauerwein Hans P., van der Poll Tom Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans Diabetes 2006;55 (6):1807-1812 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Xiao Yanling, Arens Ramon, Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Jansen Henk M., Lutter René, van der Poll Tom IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice Antiviral research 2006;70 (2):75-84 [PubMed]
  • Knapp S. Inflammatory response to severe bacterial infections 2006. 301p. ISBN 9789064640452. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.)
  • van der Sluijs Koenraad F., Nijhuis Monique, Levels Johannes H. M., Florquin Sandrine, Mellor Andrew L., Jansen Henk M., van der Poll Tom, Lutter René Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia Journal of infectious diseases 2006;193 (2):214-222 [PubMed]
  • Maris Nico A., Florquin Sandrine, van't Veer Cornelis, de Vos Alex F., Buurman Wim, Jansen Henk M., van der Poll Tom Inhalation of beta 2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract Respiratory research 2006;7:57 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, Pater Jennie M., Weijer Sebastiaan, van der Poll Tom Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract Microbes and infection / Institut Pasteur 2006;8 (9-10):2409-2413 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Shimizu Takao, Ishii Satoshi, Jansen Henk M., Lutter René, van der Poll Tom Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia American journal of physiology. Lung cellular and molecular physiology 2006;290 (1):L194-L199 [PubMed]
  • Wieland Catharina W., Stegenga Michiel E., Florquin Sandrine, Fantuzzi Giamila, van der Poll Tom Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice Shock (Augusta, Ga.) 2006;25 (4):414-419 [PubMed]
  • Rijneveld Anita W., Weijer Sebastiaan, Bresser Paul, Florquin Sandrine, Vlasuk George P., Rote William E., Spek C. Arnold, Reitsma Pieter H., van der Zee Jaring S., Levi Marcel, van der Poll Tom Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia Critical care medicine 2006;34 (6):1725-1730 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, de Vos Alex F., Lijnen H. Roger, van't Veer Cornelis, van der Poll Tom Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis Journal of immunology (Baltimore, Md. 2006;176 (6):3735-3741 [PubMed]
  • Choi Goda, Wolthuis Esther K., Bresser Paul, Levi Marcel, van der Poll Tom, Dzoljic Misa, Vroom Margreeth B., Schultz Marcus J. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury Anesthesiology 2006;105 (4):689-695 [PubMed]
  • Wiersinga W. Joost, van der Poll Tom, White Nicholas J., Day Nicholas P., Peacock Sharon J. Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei Nature reviews. Microbiology 2006;4 (4):272-282 [PubMed]
  • Leemans Jaklien C., Wieland Catharina W., Florquin Sandrine, van der Poll Tom, Vervoordeldonk Margriet J. B. M. Mice overexpressing p40 in lungs have reduced leucocyte influx and slightly impaired resistance during tuberculosis Immunology 2006;117 (3):409-418 [PubMed]
  • Maris N. A. Modulation of lung inflammation by salmeterol, a beta2 adrenergic receptor agonist 2006. 179p. ISBN 9789090198903. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Jansen H. M.; Co-supervisor: de Vos A. F.)
  • Dessing Mark C., de Vos Alex F., Florquin Sandrine, van der Poll Tom Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia Infection and immunity 2006;74 (12):7021-7023 [PubMed]
  • Bonta Peter I., van Tiel Claudia M., Vos Mariska, Pols Thijs W. H., van Thienen Johannes V., Ferreira Valérie, Arkenbout E. Karin, Seppen Jurgen, Spek C. Arnold, van der Poll Tom, Pannekoek Hans, de Vries Carlie J. M. Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses Arteriosclerosis, thrombosis, and vascular biology 2006;26 (10):2288-2294 [PubMed]
  • Levi Marcel, de Jonge Evert, van der Poll Tom Plasma and plasma components in the management of disseminated intravascular coagulation Best practice & research. Clinical haematology 2006;19 (1):127-142 [PubMed]
  • Renckens Rosemarijn, Pater Jennie M., van der Poll Tom Plasminogen activator inhibitor type-1-deficient mice have an enhanced IFN-gamma response to lipopolysaccharide and staphylococcal enterotoxin B Journal of immunology (Baltimore, Md. 2006;177 (11):8171-8176 [PubMed]
  • Weisfelt Martijn, de Gans Jan, van der Poll Tom, van de Beek Diederik Pneumococcal meningitis in adults: new approaches to management and prevention Lancet neurology 2006;5 (4):332-342 [PubMed]
  • Knapp Sylvia, Florquin Sandrine, Golenbock Douglas T., van der Poll Tom Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo Journal of immunology (Baltimore, Md. 2006;176 (5):3189-3195 [PubMed]
  • van Till J. W. O., Lamme B., van Esch T. J. H., van der Poll T., van Gulik T. M., Boermeester M. A. Surgical therapy attenuates abdominal and extra-abdominal inflammation in experimental peritonitis European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 2006;38 (2):76-82 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Knapp Sylvia, de Vos Alex F., Florquin Sandrine, van der Poll Tom The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia Journal of infectious diseases 2006;193 (2):187-195 [PubMed]
  • Choi Goda, Schultz Marcus J., Levi Marcel, van der Poll Tom The relationship between inflammation and the coagulation system Swiss medical weekly 2006;136 (9-10):139-144 [PubMed]
  • Wiersinga W. J., van der Poll T. The role of Toll-like receptors in sepsisin: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2006. S.l.: Springer-Verlag; 2006. p. 3-13
  • Roelofs J. J. T. H., Rouschop K. M. A., Teske G. J. D., Claessen N., Weening J. J., van der Poll T., Florquin S. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis Kidney international 2006;70 (11):1942-1947 [PubMed]
  • van Westerloo David J., Giebelen Ilona A., Florquin Sandrine, Bruno Marco J., Larosa Gregory J., Ulloa Luis, Tracey Kevin J., van der Poll T. The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice Gastroenterology 2006;130 (6):1822-1830 [PubMed]
  • Levi Marcel, van der Poll Tom, ten Cate Hugo Tissue factor in infection and severe inflammation Seminars in thrombosis and hemostasis 2006;32 (1):33-39 [PubMed]
  • Maris N. A., Dessing M. C., de Vos A. F., Bresser P., van der Zee J. S., Jansen H. M., Spek C. A., van der Poll T. Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin European respiratory journal 2006;28 (3):622-626 [PubMed]
  • Renckens Rosemarijn, Roelofs Joris J. T. H., Florquin Sandrine, van der Poll Tom Urokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis Journal of infectious diseases 2006;193 (4):522-530 [PubMed]
  • Rouschop Kasper M. A., Sylva Marc, Teske Gwendoline J. D., Hoedemaeker Inge, Pals Steven T., Weening Jan J., van der Poll Tom, Florquin Sandrine Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract Journal of immunology (Baltimore, Md. 2006;177 (10):7225-7232 [PubMed]
  • van Westerloo D. J., Giebelen I. A. J., Meijers J. C. M., Daalhuisen J., de Vos A. F., Levi M. [=Marcel M.], van der Poll T. Vagus nerve stimulation inhibits activation of coagulation and fibrinolysis during endotoxemia in rats Journal of thrombosis and haemostasis 2006;4 (9):1997-2002 [PubMed]

2005

  • Renckens Rosemarijn, Roelofs Joris J. T. H., ter Horst Simone A. J., van 't Veer Cornelis, Havik Stefan R., Florquin Sandrine, Wagenaar Gerry T. M., Meijers Joost C. M., van der Poll Tom Absence of thrombin-activatable fibrinolysis inhibitor protects against sepsis-induced liver injury in mice Journal of immunology (Baltimore, Md. 2005;175 (10):6764-6771 [PubMed]
  • van der Poll Tom, Levi Marcel, Nick Jerry A., Abraham Edward Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans American journal of respiratory and critical care medicine 2005;171 (10):1125-1128 [PubMed]
  • Maris Nico A., de Vos Alex F., Bresser Paul, van der Zee Jaring S., Meijers Joost C., Lijnen H. Roger, Levi Marcel, Jansen Henk M., van der Poll Tom Activation of coagulation and inhibition of fibrinolysis in the lung after inhalation of lipopolysaccharide by healthy volunteers Thrombosis and haemostasis 2005;93 (6):1036-1040 [PubMed]
  • de Fost Maaike, Chierakul Wirongrong, Pimda Kriangsak, Dondorp Arjen M., White Nicholas J., van der Poll Tom Activation of cytotoxic lymphocytes in patients with scrub typhus American journal of tropical medicine and hygiene 2005;72 (4):465-467 [PubMed]
  • van Westerloo David, van der Poll Tom Acute vagotomy activates the cholinergic anti-inflammatory pathway American journal of physiology. Heart and circulatory physiology 2005;288 (2):H977-H978 [PubMed]
  • Maris Nico A., de Vos Alex F., Dessing Mark C., Spek C. Arnold, Lutter Rene, Jansen Henk M., van der Zee Jaring S., Bresser Paul, van der Poll Tom Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers American journal of respiratory and critical care medicine 2005;172 (7):878-884 [PubMed]
  • van Westerloo David J., Knapp Sylvia, van't Veer Cornelis, Buurman Wim A., de Vos Alex F., Florquin Sandrine, van der Poll Tom Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia Critical care medicine 2005;33 (8):1770-1778 [PubMed]
  • Weijer Sebastiaan, Wieland Catharina W., Florquin Sandrine, van der Poll Tom A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis Blood 2005;106 (8):2761-2768 [PubMed]
  • Rijneveld Anita W., de Vos Alex F., Florquin Sandrine, Verbeek J. Sjef, van der Poll Tom CD11b limits bacterial outgrowth and dissemination during murine pneumococcal pneumonia Journal of infectious diseases 2005;191 (10):1755-1760 [PubMed]
  • Weijer Sebastiaan, Florquin Sandrine, van der Poll Tom Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis Shock (Augusta, Ga.) 2005;23 (1):54-58 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Arens Ramon, Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Kwakkel Joan, Akira Shizuo, Jansen Henk M., Lutter René, van der Polls Tom Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus Immunology 2005;114 (1):112-120 [PubMed]
  • Girardi Enrico, Sabin Caroline A., D'Arminio Monforte Antonella, Hogg Bob, Phillips Andrew N., Gill M. John, Dabis Francois, Reiss Peter, Kirk Ole, Bernasconi Enos, Grabar Sophie, Justice Amy, Staszewski Schlomo, Fätkenheuer Gerd, Sterne Jonathan A. C., Prins J. M., Bos J. C., Eeftinck Schattenkerk J. K. M., Geerlings S. E., Godfried M. H., Lange J. M. A., van Leth F. C., Lowe S. H., van der Meer J. T. M., Nellen F. J. B., Pogány K., van der Poll T., Ruys T. A., Sankatsing S., Steingrover R., van Twillert G., van der Valk M., van Vonderen M. G. A., Vrouenraets S. M. E., van Vugt M., Wit F. W. M. N., Kuijpers T. W., Pajkrt D., Scherpbier H. J., Veenstra J., Danner S. A., van Agtmael M. A., Claessen F. A. P., Perenboom R. M., Rijkeboer A., van Vonderen M., Back N. K. T., Bakker M. E. G., Berkhout B., Jurriaans S. Incidence of Tuberculosis among HIV-infected patients receiving highly active antiretroviral therapy in Europe and North America Clinical infectious diseases 2005;41 (12):1772-1782 [PubMed]
  • Branger Judith, Leemans Jaklien C., Florquin Sandrine, Speelman Peter, Golenbock Douglas T., van der Poll Tom Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection Clinical immunology (Orlando, Fla.) 2005;116 (2):174-181 [PubMed]
  • Leemans Jaklien C., Thepen Theo, Weijer Sebastiaan, Florquin Sandrine, van Rooijen Nico, van de Winkel Jan G., van der Poll Tom Macrophages play a dual role during pulmonary tuberculosis in mice Journal of infectious diseases 2005;191 (1):65-74 [PubMed]
  • Knapp Sylvia, Schultz Marcus J., van der Poll Tom Pneumonia models and innate immunity to respiratory bacterial pathogens Shock (Augusta, Ga.) 2005;24 (Suppl. 1):12-18 [PubMed]
  • Marshall John C., Deitch Edwin, Moldawer Lyle L., Opal Steven, Redl Heinz, van der Poll Tom Preclinical models of shock and sepsis: what can they tell us? Shock (Augusta, Ga.) 2005;24 (Suppl. 1):1-6 [PubMed]
  • Rouschop Kasper M. A., Roelofs Joris J. T. H., Rowshani Ajda T., Leemans Jaklien C., van der Poll Tom, ten Berge Ineke J. M., Weening Jan J., Florquin Sandrine Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection Nephrology, dialysis, transplantation 2005;20 (10):2248-2254 [PubMed]
  • Choi G., Schultz M. J., Levi M. [=Marcel M.], van der Poll T., Millo J. L., Garrard C. S. Protein C in pneumonia Thorax 2005;60 (8):705-706 [PubMed]
  • Choi G., Wolthuis E. K., Levi M. [=Marcel M.], van der Poll T., Schultz M. J. Pulmonary coagulation and fibrinolysis in acute lung injury and pneumonia CLIN INTENS CARE 2005;16 (1):3-10
  • Wieland Catharina W., Florquin Sandrine, Chan Edward D., Leemans Jaklien C., Weijer Sebastiaan, Verbon Annelies, Fantuzzi Giamila, van der Poll Tom Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice International immunology 2005;17 (11):1399-1408 [PubMed]
  • Leemans Jaklien C., Stokman Geurt, Claessen Nike, Rouschop Kasper M., Teske Gwendoline J. D., Kirschning Carsten J., Akira Shizuo, van der Poll Tom, Weening Jan J., Florquin Sandrine Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney Journal of clinical investigation 2005;115 (10):2894-2903 [PubMed]
  • Determann Rogier M., Millo Julian L., Gibot Sébastien, Korevaar Johanna C., Vroom Margreeth B., van der Poll Tom, Garrard Christopher S., Schultz Marcus J. Serial changes in soluble triggering receptor expressed on myeloid cells in the lung during development of ventilator-associated pneumonia Intensive care medicine 2005;31 (11):1495-1500 [PubMed]
  • Koppel Estella A., Wieland Catharina W., van den Berg Venice C. M., Litjens Manja, Florquin Sandrine, van Kooyk Yvette, van der Poll Tom, Geijtenbeek Teunis B. H. Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection European journal of immunology 2005;35 (10):2962-2969 [PubMed]
  • van Westerloo D. J., Giebelen I. A. J., van der Poll T. The central and autonomic systems: essential regulators of the immune responsein: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2005. S.l.: Springer-Verlag; 2005. p. 421-433
  • van Westerloo David J., Giebelen Ilona A. J., Florquin Sandrine, Daalhuisen Joost, Bruno Marco J., de Vos Alex F., Tracey Kevin J., van der Poll Tom The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis Journal of infectious diseases 2005;191 (12):2138-2148 [PubMed]
  • Wieland Catharina W., Florquin Sandrine, Maris Nico A., Hoebe Kasper, Beutler Bruce, Takeda Kiyoshi, Akira Shizuo, van der Poll Tom The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable Haemophilus influenzae from the mouse lung Journal of immunology (Baltimore, Md. 2005;175 (9):6042-6049 [PubMed]
  • van Westerloo David J., Florquin Sandrine, de Boer Anita M., Daalhuisen Joost, de Vos Alex F., Bruno Marco J., van der Poll Tom Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice American journal of pathology 2005;166 (3):721-728 [PubMed]
  • Renckens R., Roelofs J. J. T. H., de Waard V., Florquin S., Lijnen H. R., Carmeliet P., van der Poll T. The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury Journal of thrombosis and haemostasis 2005;3 (5):1018-1025 [PubMed]
  • van Westerloo David J., Weijer Sebastiaan, Bruno Marco J., de Vos Alex F., van't Veer Cornelis, van der Poll Tom Toll-like receptor 4 deficiency and acute pancreatitis act similarly in reducing host defense during murine Escherichia coli peritonitis Critical care medicine 2005;33 (5):1036-1043 [PubMed]
  • Wiersinga W. J., van der Poll T. 'Toll-like' receptoren en de betekenis voor de kliniek Nederlands tijdschrift voor geneeskunde 2005;149 (21):1150-1155 [PubMed]
  • Levi Marcel, van der Poll Tom Two-way interactions between inflammation and coagulation Trends in cardiovascular medicine 2005;15 (7):254-259 [PubMed]

2004

  • Knapp Sylvia, Hareng Lars, Rijneveld Anita W., Bresser Paul, van der Zee Jaring S., Florquin Sandrine, Hartung Thomas, van der Poll Tom Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia Journal of infectious diseases 2004;189 (8):1506-1514 [PubMed]
  • van Westerloo David J., Schultz Marcus J., Bruno Marco J., de Vos Alex F., Florquin Sandrine, van der Poll Tom Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis Critical care medicine 2004;32 (10):1997-2001 [PubMed]
  • Levi Marcel, Choi Goda, Schoots Ivo, Schultz Marcus, van der Poll Tom Beyond sepsis: Activated protein C and ischemia-reperfusion injury Critical care medicine 2004;32 (5 Suppl):S309-S312 [PubMed]
  • Levi Marcel, van der Poll Tom, Büller Harry R. Bidirectional relation between inflammation and coagulation Circulation 2004;109 (22):2698-2704 [PubMed]
  • Sewnath Miguel E., van der Poll Tom, van Noorden Cornelis J. F., ten Kate Fiebo J. W., Gouma Dirk J. Cholestatic interleukin-6-deficient mice succumb to endotoxin-induced liver injury and pulmonary inflammation American journal of respiratory and critical care medicine 2004;169 (3):413-420 [PubMed]
  • Levi Marcel, van der Poll Tom Coagulation in sepsis: all bugs bite equally Critical care (London, England) 2004;8 (2):99-101 [PubMed]
  • Millo Julian L., Schultz Marcus J., Williams Conrad, Weverling Gerrit J., Ringrose Timothy, Mackinlay Carolyn I., van der Poll Tom, Garrard Christopher S. Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia Intensive care medicine 2004;30 (1):68-74 [PubMed]
  • Knapp Sylvia, Gibot Sébastien, de Vos Alex, Versteeg Henri H., Colonna Marco, van der Poll Tom Cutting edge: Expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia Journal of immunology (Baltimore, Md. 2004;173 (12):7131-7134 [PubMed]
  • Chierakul Wirongrong, de Fost Maaike, Suputtamongkol Yupin, Limpaiboon Roongreung, Dondorp Arjen, White Nicholas J., van der Poll Tom Differential expression of interferon-gamma and interferon-gamma-inducing cytokines in Thai patients with scrub typhus or leptospirosis Clinical immunology (Orlando, Fla.) 2004;113 (2):140-144 [PubMed]
  • Choi G., Schultz M. J., van Till J. W. O., Bresser P., van der Zee J. S., Boermeester M. A., Levi M. [=Marcel M.], van der Poll T. Disturbed alveolar fibrin turnover during pneumonia is restricted to the site of infection European respiratory journal 2004;24 (5):786-789 [PubMed]
  • Hailu Asrat, van der Poll Tom, Berhe Nega, Kager Piet A. Elevated plasma levels of interferon (IFN)-gamma, IFN-gamma inducing cytokines, and IFN-gamma inducible CXC chemokines in visceral leishmaniasis American journal of tropical medicine and hygiene 2004;71 (5):561-567 [PubMed]
  • Schultz M. J., van der Poll T. IL-10-genpolymorfisme beinvloedt verloop van een pneumokokkeninfectie: referaat Nederlands tijdschrift voor geneeskunde 2004;147 (51):2555-2556
  • van der Sluijs Koenraad F., van Elden Leontine J. R., Nijhuis Monique, Schuurman Rob, Pater Jennie M., Florquin Sandrine, Goldman Michel, Jansen Henk M., Lutter René, van der Poll Tom IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection Journal of immunology (Baltimore, Md. 2004;172 (12):7603-7609 [PubMed]
  • Schultz M. J., Kesecioglu J., van der Poll T. Immunomodulating properties of macrolides: animal and human studies Current medicinal chemistry : Anti-infective agents 2004;3:101-107
  • Rijneveld Anita W., Weijer Sebastiaan, Florquin Sandrine, Speelman Peter, Shimizu Takao, Ishii Satosh, van der Poll Tom Improved host defense against pneumococcal pneumonia in platelet-activating factor receptor-deficient mice Journal of infectious diseases 2004;189 (4):711-716 [PubMed]
  • Hailu Asrat, Pater Jennie M., Kager Piet A., van der Poll Tom Increased expression of HIV co-receptor CXCR4 on CD4+ T-cells in patients with active visceral leishmaniasis Scandinavian journal of infectious diseases 2004;36 (1):56-58 [PubMed]
  • van der Sluijs K. F. Inflammatory response to viral airway infections and secondary bacterial complications 2004. 168p. ISBN 9789090187822. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Jansen H. M.; Co-supervisor: Lutter R.)
  • Renckens Rosemarijn, Weijer Sebastiaan, de Vos Alex F., Pater Jennie M., Meijers Joost C., Hack C. Erik, Levi Marcel, van der Poll Tom Inhibition of plasmin activity by tranexamic acid does not influence inflammatory pathways during human endotoxemia Arteriosclerosis, thrombosis, and vascular biology 2004;24 (3):483-488 [PubMed]
  • Weijer Sebastian, Schoenmakers Saskia H. H. F., Florquin Sandrine, Levi Marcel, Vlasuk George P., Rote William E., Reitsma Pieter H., Spek C. Arnold, van der Poll Tom Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice Journal of infectious diseases 2004;189 (12):2308-2317 [PubMed]
  • Moons A. H. M., Bijsterveld N. R., Koch K. T., Meijers J. C. M., Tijssen J. G. P., van der Poll T., Büller H. R., Peters R. J. G. Inhibition of the tissue factor pathway of coagulation by recombinant nematode anticoagulant protein c2 during elective coronary stent implantation Netherlands heart journal 2004;12 (2):48-54
  • Weijer S. Interaction between inflammation, coagulation and fibrinolysis during infection 2004. 194p. ISBN 9789090179285. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van der Poll T.)
  • Fontas E., van Leth F., Sabin C. A., Friis-Møller N., Rickenbach M., d'Arminio Monforte A., Kirk O., Dupon M., Morfeldt L., Mateu S., Petoumenos K., El-Sadr W., de Wit S., Lundgren J. D., Pradier C., Reiss P., de Wolf F., van der Ven E., Zaheri S., van Valkengoed I., Meester R., Weigel H., Brinkman K., Frissen P., ten Veen J., Hillebrand M., van Dam P., Schieveld S., Mulder J., van Gorp E., Meenhorst P., van Eeden A., Danner S., Claessen F., Perenboom R., Eeftinck Schattenkerk J. K., Godfried M., Lange J., Lowe S., van der Meer J., Nellen F., Pogany K., van der Poll T., Prins J., Ruys T., van Agtmael M., van der Valk M., Wit F. Lipid profiles in HIV-infected patients receiving combination antiretroviral therapy: Are different antiretroviral drugs associated with different lipid profiles? Journal of infectious diseases 2004;189 (6):1056-1074 [PubMed]
  • Schultz M. J., Millo J., Levi M. [=Marcel M.], Hack C. E., Weverling G. J., Garrard C. S., van der Poll T. Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia Thorax 2004;59 (2):130-135 [PubMed]
  • Zwijnenburg P. J. G. Local inflammatory response in bacterial meningitis 2004. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Roord J. J.; Co-supervisor: van Furth A. M.)
  • Branger Judith, Florquin Sandrine, Knapp Sylvia, Leemans Jaklien C., Pater Jennie M., Speelman Peter, Golenbock Douglas T., van der Poll Tom LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia International immunology 2004;16 (11):1605-1611 [PubMed]
  • van der Poll Tom, Levi Marcel Mechanisms of action of activated protein C: An evolving story Critical care medicine 2004;32 (4):1086-1087 [PubMed]
  • Branger J. Mechanisms of immune activation during infection 2004. 195p. ISBN 9789090179056. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Poll T., Speelman P.)
  • Schultz Marcus J., van der Poll Tom Modulation of innate immune responses in the treatment of sepsis and pneumonia Current drug targets. Inflammation and allergy 2004;3 (1):11-17 [PubMed]
  • Levi Marcel, de Jonge Evert, van der Poll Tom New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology Annals of medicine 2004;36 (1):41-49 [PubMed]
  • Wieland Catharina W., Knapp Sylvia, Florquin Sandrine, de Vos Alex F., Takeda Kiyoshi, Akira Shizuo, Golenbock Douglas T., Verbon Annelies, van der Poll Tom Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2 American journal of respiratory and critical care medicine 2004;170 (12):1367-1374 [PubMed]
  • van den Blink Bernt, Branger Judith, Weijer Sebastiaan, Gupta Abhya, van Deventer Sander J. H., Peppelenbosch Maikel P., van der Poll Tom P38 mitogen activated protein kinase is involved in the downregulation of granulocyte CXC chemokine receptors 1 and 2 during human endotoxemia Journal of clinical immunology 2004;24 (1):37-41 [PubMed]
  • Branger Judith, Wieland Catharina W., Florquin Sandrine, Maris Nico A., Pater Jennie M., Speelman Peter, Shimizu Takao, Ishii Satoshi, van der Poll Tom Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable Haemophilus influenzae from their respiratory tract Shock (Augusta, Ga.) 2004;22 (6):543-547 [PubMed]
  • Ledergerber Bruno, Lundgren Jens D., Walker A. Sarah, Sabin Caroline, Justice Amy, Reiss Peter, Mussini Cristina, Wit Ferdinand, D'Arminio Monforte Antonella, Weber Rainer, Fusco Gregory, Staszewski Schlomo, Law Matthew, Hogg Robert, Lampe Fiona, Gill M. John, Castelli Francesco, Phillips Andrew N., de Wolf F., van Sighem A. I., van Valkengoed I., Gras L., Prins J. M., Bos J. C., Eeftinck Schattenkerk J. K. M., Godfried M. H., Lange J. M. A., Lowe S. H., van der Meer J. T. M., Nellen F. J. B., Pogany K., van der Poll T., Ruys T. A., Sankatsing S., van der Valk M., van Vonderen M. G. A., van Eeden A., ten Veen J. H., van Dam P. S., Hillebrand-Haverkort M. E., Brinkman K., Frissen P. H. J., Weigel H. M., Mulder J. W., van Gorp E. C. M., Meenhorst P. L., Mairuhu A. T. A., Veenstra J., Danner S. A., Geerlings S. E. Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes Lancet 2004;364 (9428):51-62 [PubMed]
  • Heesen Michael, Kunz Dagmar, Wessiepe Martina, van der Poll Tom, Zwinderman Aeilko H., Blomeke Brunhilde Rapid genotyping for tumor necrosis factor-alpha (TNF-alpha)-863C/A promoter polymorphism that determines TNF-alpha response Clinical chemistry 2004;50 (1):226-228 [PubMed]
  • de Pont A. C. J. M., Moons A. H. M., de Jonge E., Meijers J. C. M., Vlasuk G. P., Rote W. E., Büller H. R., van der Poll T., Levi M. [=Marcel M.] Recombinant nematode anticoagulant protein c2, an inhibitor of tissue factor/factor VIIa, attenuates coagulation and the interleukin-10 response in human endotoxemia Journal of thrombosis and haemostasis 2004;2 (1):65-70 [PubMed]
  • Branger Judith, Knapp Sylvia, Weijer Sebastiaan, Leemans Jaklien C., Pater Jennie M., Speelman Peter, Florquin Sandrine, van der Poll Tom Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice Infection and immunity 2004;72 (2):788-794 [PubMed]
  • Maris Nico A., van der Sluijs Koenraad F., Florquin Sandrine, de Vos Alex F., Pater Jennie M., Jansen Henk M., van der Poll Tom Salmeterol, a beta(2)-receptor agonist, attenuates lipopolysaccharide-induced lung inflammation in mice American journal of physiology. Lung cellular and molecular physiology 2004;286 (6):L1122-L1128 [PubMed]
  • Levi M. [=Marcel M.], van der Poll T. The central role of the endothelium in the crosstalk between coagulation and inflammation in sepsis Advances in sepsis 2004;3 (3):91-97
  • Leemans Jaklien C., te Velde Anje A., Florquin Sandrine, Bennink Roelof J., de Bruin Kora, van Lier René A. W., van der Poll Tom, Hamann Jörg The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense Journal of immunology (Baltimore, Md. 2004;172 (2):1125-1131 [PubMed]
  • Rijneveld Anita W., Weijer Sebastiaan, Florquin Sandrine, Esmon Charles T., Meijers Joost C. M., Speelman Peter, Reitsma Pieter H., ten Cate Hugo, van der Poll Tom Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide Blood 2004;103 (5):1702-1709 [PubMed]
  • Knapp Sylvia, Wieland Catharina W., van 't Veer Cornelis, Takeuchi Osamu, Akira Shizuo, Florquin Sandrine, van der Poll Tom Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense Journal of immunology (Baltimore, Md. 2004;172 (5):3132-3138 [PubMed]
  • Branger Judith, Leemans Jaklien C., Florquin Sandrine, Weijer Sebastiaan, Speelman Peter, van der Poll Tom Toll-like receptor 4 plays a protective role in pulmonary tuberculosis in mice International immunology 2004;16 (3):509-516 [PubMed]
  • Knapp S., van der Poll T. Update on CD14, LBP and Toll-like receptors in acute infectionsin: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2004. Berlin: Springer-Verlag; 2004. p. 254-264

2003

  • de Jonge Evert, Friederich Philip W., Vlasuk George P., Rote William E., Vroom Margaretha B., Levi Marcel, van der Poll Tom Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects Clinical and diagnostic laboratory immunology 2003;10 (3):495-497 [PubMed]
  • Schultz M. J., van der Poll T. Acute lung injury and pneumonia in micein: C. Ince, editors. The physiological genomics of the critically ill mouse. S.l.: Luwer Academic Publishers; 2003. p. 275-287
  • Levi Marcel, Dörffler-Melly Janine, Reitsma Pieter, Buller Harry, Florquin Sandrine, van der Poll Tom, Carmeliet Peter Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice Blood 2003;101 (12):4823-4827 [PubMed]
  • Knapp Sylvia, Leemans Jaklien C., Florquin Sandrine, Branger Judith, Maris Nico A., Pater Jennie, van Rooijen Nico, van der Poll Tom Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia American journal of respiratory and critical care medicine 2003;167 (2):171-179 [PubMed]
  • Schultz Marcus J., Levi Marcel, van der Poll Tom Anticoagulant therapy for acute lung injury or pneumonia Current drug targets 2003;4 (4):315-321 [PubMed]
  • Rijneveld Anita W., Florquin Sandrine, Hartung Thomas, Speelman Peter, van der Poll Tom Anti-tumor necrosis factor antibody impairs the therapeutic effect of ceftriaxone in murine pneumococcal pneumonia Journal of infectious diseases 2003;188 (2):282-285 [PubMed]
  • Levi Marcel, Schultz Marcus J., Rijneveld Anita W., van der Poll Tom Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia Critical care medicine 2003;31 (4 Suppl):S238-S242 [PubMed]
  • van Westerloo D. J., Maris N. A., Bruno M. J., van der Poll T. Caerulein induced pancreatitis Gut 2003;52 (3):452-453 [PubMed]
  • Leemans Jaklien C., Florquin Sandrine, Heikens Mirjam, Pals Steven T., van der Neut Ronald, van der Poll Tom CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis Journal of clinical investigation 2003;111 (5):681-689 [PubMed]
  • Zwijnenburg Petra J. G., de Bie Henrica M. A., Roord John J., van der Poll Tom, van Furth A. Marceline Chemotactic activity of CXCL5 in cerebrospinal fluid of children with bacterial meningitis Journal of neuroimmunology 2003;145 (1-2):148-153 [PubMed]
  • Friis-Møller Nina, Sabin Caroline A., Weber Rainer, D'Arminio Monforte Antonella, El-Sadr Wafaa M., Reiss Peter, Thiébaut Rodolphe, Morfeldt Linda, de Wit Stephane, Pradier Christian, Calvo Gonzalo, Law Matthew G., Kirk Ole, Phillips Andrew N., Lundgren Jens D., de Wolf F., van der Ven E., Zaheri S., van Valkengoed I., Meester R., Weigel H., Brinkman K., Frissen P., ten Veen J., Hillebrand M., van Dam P., Schieveld S., Mulder J., van Gorp E., Meenhorst P., van Eeden A., Danner S., Claessen F., Perenboom R., Eeftinck Schattenkerk J. K., Godfried M., Lange J., Lowe S., van der Meer J., Nellen F., Pogany K., van der Poll T., Prins J., Ruys T., van Agtmael M., van der Valk M., Wit F. Combination antiretroviral therapy and the risk of myocardial infarction New England journal of medicine 2003;349 (21):1993-2003 [PubMed]
  • Zwijnenburg Petra J. G., Polfliet Machteld M. J., Florquin Sandrine, van den Berg Timo K., Dijkstra Christine D., van Deventer Sander J. H., Roord John J., van der Poll Tom, van Furth A. Marceline CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats Immunology letters 2003;85 (1):1-4 [PubMed]
  • van der Poll T., de Jonge E., ten Cate H., Levi M. M. Cytokines as regulators of coagulation and fibrinolysisin: H. ten Cate, M. M. Levi, editors. Molecular mechanisms of disseminated intravascular coagulation. Georgtown, Texas: Landes Bioscience Publishers; 2003. p. 120-134
  • Olszyna Dariusz P., Verbon Annelies, Pribble John P., Turner Terence, Axtelle Tim, van Deventer Sander J. H., van der Poll Tom Effect of IC14, an anti-CD14 antibody, on plasma and cell-associated chemokines during human endotoxemia European cytokine network 2003;14 (3):158-162 [PubMed]
  • Verbon Annelies, Meijers Joost C. M., Spek C. Arnold, Hack C. Erik, Pribble John P., Turner Terence, Dekkers Pascale E. P., Axtelle Tim, Levi Marcel, van Deventer Sander J. H., Reitsma Pieter H., van der Poll Tom Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans Journal of infectious diseases 2003;187 (1):55-61 [PubMed]
  • Weijer Sebastiaan, Leemans Jaklien C., Florquin Sandrine, Shimizu Takao, Ishii Satoshi, van der Poll Tom Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis Immunology 2003;109 (4):552-556 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Roord John J., van Furth A. Marceline IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis Journal of immunology (Baltimore, Md. 2003;170 (9):4724-4730 [PubMed]
  • Stordeur Patrick, Zhou Ling, Byl Baudouin, Brohet Fabian, Burny Wivine, de Groote Donat, van der Poll Tom, Goldman Michel Immune monitoring in whole blood using real-time PCR Journal of immunological methods 2003;276 (1-2):69-77 [PubMed]
  • Sewnath M. E. Inflammatory response in obstructive jaundice and peritonitis 2003. 204p. ISBN 9789090161952. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Gouma D. J.; Co-supervisor: van der Poll T.)
  • Branger Judith, van den Blink Bernt, Weijer Sebastiaan, Gupta Abhya, van Deventer Sander J. H., Hack C. Erik, Peppelenbosch Maikel P., van der Poll Tom Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia Blood 2003;101 (11):4446-4448 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Roord John J., van Furth A. Marceline Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis Infection and immunity 2003;71 (4):2276-2279 [PubMed]
  • de Fost Maaike, Hartskeerl Rudy A., Groenendijk Martijn R., van der Poll Tom Interleukin 12 in part regulates gamma interferon release in human whole blood stimulated with Leptospira interrogans Clinical and diagnostic laboratory immunology 2003;10 (2):332-335 [PubMed]
  • Weijer Sebastiaan, Sewnath Miguel E., de Vos Alex F., Florquin Sandrine, van der Sluis Koen, Gouma Dirk J., Takeda Kiyoshi, Akira Shizuo, van der Poll Tom Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis Infection and immunity 2003;71 (10):5488-5497 [PubMed]
  • Zwijnenburg Petra J. G., van der Poll Tom, Florquin Sandrine, Akira Shizuo, Takeda Kiyoshi, Roord John J., van Furth A. Marceline Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis Journal of neuroimmunology 2003;138 (1-2):31-37 [PubMed]
  • Schultz Marc J., Knapp Sylvia, Florquin Sandrine, Pater Jennie, Takeda Kiyoshi, Akira Shizuo, van der Poll Tom Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa Infection and immunity 2003;71 (4):1630-1634 [PubMed]
  • Rijneveld Anita W., Florquin Sandrine, Speelman Peter, Edwards Carl K., Dinarello Charles A., van der Poll Tom Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia European cytokine network 2003;14 (4):242-245 [PubMed]
  • Knapp Sylvia, de Vos Alex F., Florquin Sandrine, Golenbock Douglas T., van der Poll Tom Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice Infection and immunity 2003;71 (12):6747-6753 [PubMed]
  • Leemans Jaklien C., Heikens Mirjam, van Kessel Kok P. M., Florquin Sandrine, van der Poll Tom Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice Clinical and diagnostic laboratory immunology 2003;10 (5):950-953 [PubMed]
  • Schultz M. J., van der Poll T., Kesecioglu J. Modulation of the innate immune response during respiratory tract infectionsin: A. Gullo, editors. Anaesthesia pain intensive care and emergency medicine (A.P.I.C.E.). Millano: Springer-Verlag; 2003. p. 1231-1238
  • van Westerloo D. J., Bruno M. J., van der Poll T. New insights into pathophysiology and severity assessment of acute pancreatitisin: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2003. S.l.: Springer-Verlag; 2003. p. 823-837
  • Rijneveld Anita W., Florquin Sandrine, Bresser Paul, Levi Marcel, de Waard Vivian, Lijnen Roger, van der Zee Jaring S., Speelman Peter, Carmeliet Peter, van der Poll Tom Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia Blood 2003;102 (3):934-939 [PubMed]
  • Rijneveld A. W. Pneumomia: an investigation of host defence mechanisms 2003. 203p. ISBN 9789064645792. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Speelman P.; Co-supervisor: van der Poll T.)
  • Reitsma P. H., Branger J., van den Blink B., Weijer S., van der Poll T., Meijers J. C. M. Procoagulant protein levels are differentially increased during human endotoxemia Journal of thrombosis and haemostasis 2003;1 (5):1019-1023 [PubMed]
  • Lettinga K. D., Weijer S., Speelman P., Prins J. M., van der Poll T., Verbon A. Reduced interferon-gamma release in patients recovered from Legionnaires' disease Thorax 2003;58 (1):63-67 [PubMed]
  • Levi Marcel, de Jonge Evert, van der Poll Tom Sepsis and disseminated intravascular coagulation Journal of thrombosis and thrombolysis 2003;16 (1-2):43-47 [PubMed]
  • van der Sluijs Koenraad F., van Elden Leontine, Nijhuis Monique, Schuurman Rob, Florquin Sandrine, Jansen Henk M., Lutter René, van der Poll Tom Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus Immunology letters 2003;89 (2-3):201-206 [PubMed]
  • Spek C. Arnold, Verbon Annelies, Aberson Hella, Pribble John P., McElgunn Cathal J., Turner Terence, Axtelle Tim, Schouten Jan, van der Poll Tom, Reitsma Pieter H. Treatment with an anti-CD14 monoclonal antibody delays and inhibits lipopolysaccharide-induced gene expression in humans in vivo Journal of clinical immunology 2003;23 (2):132-140 [PubMed]

2002

  • Knapp Sylvia, Branger Judith, van der Poll T. Advances in research of the inflammatory response: the importance of toll-like receptors Wiener medizinische Wochenschrift (1946) 2002;152 (21-22):552-554 [PubMed]
  • Schultz Marc J., van der Poll Tom Animal and human models for sepsis Annals of medicine 2002;34 (7-8):573-581 [PubMed]
  • Branger Judith, van den Blink Bernt, Weijer Sebastiaan, Madwed Jeffrey, Bos Carina L., Gupta Abhya, Yong Chan-Loi, Polmar Stephen H., Olszyna Dariusz P., Hack C. Erik, van Deventer Sander J. H., Peppelenbosch Maikel P., van der Poll Tom Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia Journal of immunology (Baltimore, Md. 2002;168 (8):4070-4077 [PubMed]
  • Levi M. M., van der Poll T. Coagulation abnormalities in sepsisin: E. A. Deitch, J. L. Vincent, A. Windsor, editors. Sepsis and multiple organ dysfunction: A multidisciplinary approach. London etc: W.B.Saunders; 2002. p. 91-94
  • Juffermans Nicole P., Leemans Jaklien C., Florquin Sandrine, Verbon Annelies, Kolk Arend H., Speelman Peter, van Deventer Sander J. H., van der Poll Tom CpG oligodeoxynucleotides enhance host defense during murine tuberculosis Infection and immunity 2002;70 (1):147-152 [PubMed]
  • Juffermans Nicole P., Verbon Annelies, van der Poll Tom Diabetes insipidus as a complication of cryptococcal meningitis in an HIV-infected patient Scandinavian journal of infectious diseases 2002;34 (5):397-398 [PubMed]
  • Leemans Jaklien C., Vervoordeldonk Margriet J. B. M., Florquin Sandrine, van Kessel Kok P., van der Poll Tom Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus American journal of respiratory and critical care medicine 2002;165 (10):1445-1450 [PubMed]
  • Weijer Sebastiaan, Lauw Fanny N., Branger Judith, van den Blink Bernt, van der Poll Tom Diminished interferon-gamma production and responsiveness after endotoxin administration to healthy humans Journal of infectious diseases 2002;186 (12):1748-1753 [PubMed]
  • Sewnath Miguel E., van der Poll Tom, van Noorden Cornelis J. F., ten Kate Fiebo J. W., Gouma Dirk J. Endogenous interferon gamma protects against cholestatic liver injury in mice Hepatology (Baltimore, Md.) 2002;36 (6):1466-1477 [PubMed]
  • Levi Marcel, ten Cate Hugo, van der Poll Tom Endothelium: interface between coagulation and inflammation Critical care medicine 2002;30 (5 Suppl):S220-S224 [PubMed]
  • Juffermans Nicole P., Weijer Sebastiaan, Verbon Annelies, Speelman Peter, van der Poll Tom Expression of human immunodeficiency virus coreceptors CXC chemokine receptor 4 and CC chemokine receptor 5 on monocytes is down-regulated during human endotoxemia Journal of infectious diseases 2002;185 (7):986-989 [PubMed]
  • Lauw Fanny N., Branger Judith, Florquin Sandrine, Speelman Peter, van Deventer Sander J. H., Akira Shizuo, van der Poll Tom IL-18 improves the early antimicrobial host response to pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2002;168 (1):372-378 [PubMed]
  • Schultz M. J., van der Poll T. Immunomodulerende strategieën in de behandeling bij sepsis Nederlands tijdschrift voor geneeskunde 2002;146 (52):2530-2533 [PubMed]
  • Schultz M. J. Innate immunity against respiratory pathogens 2002. 224p. ISBN 9789090160344. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Deventer S. J. H., Speelman P.; Co-supervisor: van der Poll T.)
  • Sewnath Miguel E., van der Poll Tom, ten Kate Fiebo J. W., van Noorden Cornelis J. F., Gouma Dirk J. Interleukin-1 receptor type I gene-deficient bile duct-ligated mice are partially protected against endotoxin Hepatology (Baltimore, Md.) 2002;35 (1):149-158 [PubMed]
  • van den Blink B. In vivo signal transduction: mitogen activated protein kinases in inflammation 2002. 176p. ISBN 9789090160122. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Deventer S. J. H.; Co-supervisors: Peppelenbosch M. P., van der Poll T.)
  • Verbon A., Leemans J. C., Weijer S., Florquin S., van der Poll T. Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis Clinical and experimental immunology 2002;130 (1):32-36 [PubMed]
  • Schultz Marcus J., van der Poll Tom Modulation of pulmonary innate immunity during bacterial infection: Animal studies Archivum immunologiae et therapiae experimentalis 2002;50 (3):159-167 [PubMed]
  • Levi M. M., de Jonge E., van der Poll T. Pathogenesis and treatment of disseminated intravascular coagulation Advances in sepsis 2002;2:79-85
  • Leemans J. C. Pulmonary immune response during (myco)bacterial infection 2002. 205p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Deventer S. J. H.; Co-supervisor: van der Poll T.)
  • Levi M. [=Marcel M.], de Jonge E., van der Poll T. Recombinant human activated protein C (Xigris) International journal of clinical practice 2002;56 (7):542-545 [PubMed]
  • Schultz M. J., Knapp S., van der Poll T. Regulatory role of alveolar macrophages and cytokines in pulmonary host defensein: J. L. Vincent, editors. Yearbook of intensive care and emergency medicine 2002. Berlin: Springer-Verlag; 2002. p. 65-76
  • Schultz Marc J., Rijneveld Anita W., Florquin Sandrine, Edwards Carl K., Dinarello Charles A., van der Poll Tom Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia American journal of physiology. Lung cellular and molecular physiology 2002;282 (2):L285-L290 [PubMed]
  • Rijneveld Anita W., van den Dobbelsteen Germie P., Florquin Sandrine, Standiford Theodore J., Speelman Peter, van Alphen Loek, van der Poll Tom Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice Journal of infectious diseases 2002;185 (1):123-126 [PubMed]
  • Levi Marcel, de Jonge Evert, van der Poll Tom Therapeutic intervention in disseminated intravascular coagulation: have we made any progress in the last millennium? Blood reviews 2002;16 (Suppl. 1):S29-S34 [PubMed]
  • Lauw F. N., van Deventer S. J. H., van der Poll T. The role of IL-10 during systemic inflammation and bacterial infectionin: A. E. Baue, G. Berlot, J. L. Vincent, editors. Sepsis and organ dysfunction: from chaos to rationale. Berlin: Springer-Verlag; 2002. p. 95-102
  • Rijneveld Anita W., Lauw Fanny N., Schultz Marc J., Florquin Sandrine, te Velde Anje A., Speelman Peter, van Deventer Sander J. H., van der Poll Tom The role of interferon-gamma in murine pneumococcal pneumonia Journal of infectious diseases 2002;185 (1):91-97 [PubMed]
  • van der Poll T. The role of interleukin 6 in endotoxin-induced inflammatory responses Advances in sepsis 2002;2 (2):42-48
  • Lettinga Kamilla D., Florquin Sandrine, Speelman Peter, van Ketel Ruud, van der Poll Tom, Verbon Annelies Toll-like receptor 4 is not involved in host defense against pulmonary Legionella pneumophila infection in a mouse model Journal of infectious diseases 2002;186 (4):570-573 [PubMed]
  • Rijneveld Anita W., Levi Marcel, Florquin Sandrine, Speelman Peter, Carmeliet Peter, van der Poll Tom Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2002;168 (7):3507-3511 [PubMed]

2001

  • Levi M. [=Marcel M.], de Jonge E., van der Poll T., ten Cate H. Advances in the understanding of the pathogenetic pathways of disseminated intravascular coagulation result in more insight in the clinical picture and better management strategies Seminars in thrombosis and hemostasis 2001;27 (6):569-575 [PubMed]
  • de Jonge E., van der Poll T., Kesecioglu J., Levi M. [=Marcel M.] Anticoagulant factor concentrates in disseminated intravascular coagulation: rationale for use and clinical experience Seminars in thrombosis and hemostasis 2001;27 (6):667-674 [PubMed]
  • Burger D. M., Hugen P. W., Aarnoutse R. E., Dieleman J. P., Prins J. M., van der Poll T., ten Veen J. H., Mulder J. W., Meenhorst P. L., Blok W. L., van der Meer J. T., Reiss P., Lange J. M. A retrospective, cohort-based survey of patients using twice-daily indinavir + ritonavir combinations: pharmacokinetics, safety, and efficacy JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2001;26 (3):218-224 [PubMed]
  • van der Poll T. Coagulation and inflammation Journal of endotoxin research 2001;7 (4):301-304 [PubMed]
  • Juffermans N. P., Dekkers P. E., Verbon A., Speelman P., van Deventer S. J., van der Poll T. Concurrent upregulation of urokinase plasminogen activator receptor and CD11b during tuberculosis and experimental endotoxemia Infection and immunity 2001;69 (8):5182-5185 [PubMed]
  • Olszyna D. P., Florquin S., Sewnath M., Branger J., Speelman P., van Deventer S. J., Strieter R. M., van der Poll T. CXC chemokine receptor 2 contributes to host defense in murine urinary tract infection Journal of infectious diseases 2001;184 (3):301-307 [PubMed]
  • Leemans J. C., Juffermans N. P., Florquin S., van Rooijen N., Vervoordeldonk M. J., Verbon A., van Deventer S. J., van der Poll T. Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice Journal of immunology (Baltimore, Md. 2001;166 (7):4604-4611 [PubMed]
  • Olszyna D. P., Pajkrt D., van Deventer S. J., van der Poll T. Effect of interleukin 10 on the release of the CXC chemokines growth related oncogene GRO-alpha and epithelial cell-derived neutrophil activating peptide (ENA)-78 during human endotoxemia Immunology letters 2001;78 (1):41-44 [PubMed]
  • Van der Poll T. Effects of catecholamines on the inflammatory response Sepsis 2001;4 (2):159-167
  • Schultz M. J., Rijneveld A. W., Speelman P., van Deventer S. J., van der Poll T. Endogenous interferon-gamma impairs bacterial clearance from lungs during Pseudomonas aeruginosa pneumonia European cytokine network 2001;12 (1):39-44 [PubMed]
  • Schultz M. J., Speelman P., van der Poll T. Erythromycin inhibits Pseudomonas aeruginosa-induced tumour necrosis factor-alpha production in human whole blood Journal of antimicrobial chemotherapy 2001;48 (2):275-278 [PubMed]
  • Zwijnenburg P. J., van der Poll T., Florquin S., van Deventer S. J., Roord J. J., van Furth A. M. Experimental pneumococcal meningitis in mice: a model of intranasal infection Journal of infectious diseases 2001;183 (7):1143-1146 [PubMed]
  • van den Blink B., Branger J., Weijer S., Deventer S. H., van der Poll T., Peppelenbosch M. P. Human endotoxemia activates p38 MAP kinase and p42/44 MAP kinase, but not c-Jun N-terminal kinase Molecular medicine (Cambridge, Mass.) 2001;7 (11):755-760 [PubMed]
  • Verbon A., Dekkers P. E., ten Hove T., Hack C. E., Pribble J. P., Turner T., Souza S., Axtelle T., Hoek F. J., van Deventer S. J., van der Poll T. IC14, an anti-CD14 antibody, inhibits endotoxin-mediated symptoms and inflammatory responses in humans Journal of immunology (Baltimore, Md. 2001;166 (5):3599-3605 [PubMed]
  • Sewnath M. E., Olszyna D. P., Birjmohun R., ten Kate F. J., Gouma D. J., van der Poll T. IL-10-deficient mice demonstrate multiple organ failure and increased mortality during Escherichia coli peritonitis despite an accelerated bacterial clearance Journal of immunology (Baltimore, Md. 2001;166 (10):6323-6331 [PubMed]
  • Van Der Poll Tom Immunotherapy of sepsis Lancet infectious diseases 2001;1 (3):165-174 [PubMed]
  • Schultz M. J., Rijneveld A. W., Florquin S., Speelman P., van Deventer S. J., van der Poll T. Impairment of host defence by exotoxin A in Pseudomonas aeruginosa pneumonia in mice Journal of medical microbiology 2001;50 (9):822-827 [PubMed]
  • Olszyna D. P., de Jonge E., Dekkers P. E., van Deventer S. J., van der Poll T. Induction of cell-associated chemokines after endotoxin administration to healthy humans Infection and immunity 2001;69 (4):2736-2738 [PubMed]
  • Polfliet M. M., Zwijnenburg P. J., van Furth A. M., van der Poll T., Döpp E. A., Renardel de Lavalette C., van Kesteren-Hendrikx E. M., van Rooijen N., Dijkstra C. D., van den Berg T. K. Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis Journal of immunology (Baltimore, Md. 2001;167 (8):4644-4650 [PubMed]
  • Schultz M. J., Wijnholds J., Peppelenbosch M. P., Vervoordeldonk M. J., Speelman P., van Deventer S. J., Borst P., van der Poll T. Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia Journal of immunology (Baltimore, Md. 2001;166 (6):4059-4064 [PubMed]
  • Lauw F. N., van der Meer J. T., de Metz J., Danner S. A., van der Poll T. No beneficial effect of interferon-gamma treatment in 2 human immunodeficiency virus-infected patients with Mycobacterium avium complex infection Clinical infectious diseases 2001;32 (4):e81-e82 [PubMed]
  • van den Blink B., Juffermans N. P., ten Hove T., Schultz M. J., van Deventer S. J., van der Poll T., Peppelenbosch M. P. p38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivo Journal of immunology (Baltimore, Md. 2001;166 (1):582-587 [PubMed]
  • Juffermans N. P., Speelman P., Verbon A., Veenstra J., Jie C., van Deventer S. J., van der Poll T. Patients with active tuberculosis have increased expression of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells Clinical infectious diseases 2001;32 (4):650-652 [PubMed]
  • Guchelaar H. J., Schultz M. J., van der Poll T., Koopmans R. P. Pharmacokinetic-pharmacodynamic modeling of the inhibitory effect of erythromycin on tumour necrosis factor-alpha and interleukin-6 production Fundamental & clinical pharmacology 2001;15 (6):419-424 [PubMed]
  • Levi M. [=Marcel M.], de Jonge E., van der Poll T. Rationale for restoration of physiological anticoagulant pathways in patients with sepsis and disseminated intravascular coagulation Critical care medicine 2001;29 (7 Suppl):S90-S94 [PubMed]
  • van der Poll T., de Jonge E., Levi M. [=Marcel M.] Regulatory role of cytokines in disseminated intravascular coagulation Seminars in thrombosis and hemostasis 2001;27 (6):639-651 [PubMed]
  • Florquin S., van den Berg J. G., Olszyna D. P., Claessen N., Opal S. M., Weening J. J., van der Poll T. Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia Kidney international 2001;59 (6):2054-2061 [PubMed]
  • Lauw F. N., Florquin S., Speelman P., van Deventer S. J., van der Poll T. Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice Infection and immunity 2001;69 (9):5949-5952 [PubMed]
  • Juffermans N. P., Verbon A., Schultz M. J., Hack C. E., van Deventer S. J., Speelman P., van der Poll T. Thalidomide inhibits granulocyte responses in healthy humans after ex vivo stimulation with bacterial antigens Antimicrobial agents and chemotherapy 2001;45 (5):1547-1549 [PubMed]
  • de Jonge E., Dekkers P. E., Creasey A. A., Hack C. E., Paulson S. K., Karim A., Kesecioglu J., Levi M. [=Marcel M.], van Deventer S. J., van der Poll T. Tissue factor pathway inhibitor does not influence inflammatory pathways during human endotoxemia Journal of infectious diseases 2001;183 (12):1815-1818 [PubMed]
  • Rijneveld A. W., Florquin S., Branger J., Speelman P., van Deventer S. J., van der Poll T. TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia Journal of immunology (Baltimore, Md. 2001;167 (9):5240-5246 [PubMed]
  • Olszyna D. P., Vermeulen H., Baan A. H., Speelman P., van Deventer S. J., Gouma D. J., van der Poll T. Urine interleukin-8 is a marker for urinary tract infection in postoperative patients Infection 2001;29 (5):274-277 [PubMed]

2000

  • Verbon A., Juffermans N. P., Speelman P., van Deventer S. J., ten Berge I. J., Guchelaar H. J., van der Poll T. A single oral dose of thalidomide enhances the capacity of lymphocytes to secrete gamma interferon in healthy humans Antimicrobial agents and chemotherapy 2000;44 (9):2286-2290 [PubMed]
  • Boelens J. J., Dankert J., Murk J. L., Weening J. J., van der Poll T., Dingemans K. P., Koole L., Laman J. D., Zaat S. A. Biomaterial-associated persistence of Staphylococcus epidermidis in pericatheter macrophages Journal of infectious diseases 2000;181 (4):1337-1349 [PubMed]
  • Enting R. H., Foudraine N. A., Lange J. M., Jurriaans S., van der Poll T., Weverling G. J., Portegies P. Cerebrospinal fluid beta2-microglobulin, monocyte chemotactic protein-1, and soluble tumour necrosis factor alpha receptors before and after treatment with lamivudine plus zidovudine or stavudine Journal of neuroimmunology 2000;102 (2):216-221 [PubMed]
  • Wagenaar G. T., van Vuuren A. J., Girma M., Tiekstra M. J., Kwast L., Koster J. G., Rijneveld A. W., Elisen M. G., van der Poll T., Meijers J. C. Characterization of transgenic mice that secrete functional human protein C inhibitor into the circulation Thrombosis and haemostasis 2000;83 (1):93-101 [PubMed]
  • Olszyna D. P., Opal S. M., Prins J. M., Horn D. L., Speelman P., van Deventer S. J., van der Poll T. Chemotactic activity of CXC chemokines interleukin-8, growth-related oncogene-alpha, and epithelial cell-derived neutrophil-activating protein-78 in urine of patients with urosepsis Journal of infectious diseases 2000;182 (6):1731-1737 [PubMed]
  • De Jonge Evert, Levi Marcel, Van Der Poll Tom Coagulation abnormalities in sepsis: Relation with inflammatory responses Current opinion in critical care 2000;6 (5):317-322
  • Zwijnenburg P. J.G., Van Der Poll T., Florquin S., Van Deventer S. J.H., Roord J. J., Van Furth A. M. Een nieuw muizenmodel voor bacteriële meningitis; inzicht in de rol van cytokines Tijdschrift voor kindergeneeskunde 2000;68 (SUPPL. 1):116
  • Dekkers P. E., Juffermans N. P., ten Hove T., de Jonge E., van Deventer S. J., van der Poll T. Endotoxin down-regulates monocyte and granulocyte interleukin-6 receptors without influencing gp130 expression in humans Journal of infectious diseases 2000;181 (3):1055-1061 [PubMed]
  • Boelens J. J., Zaat S. A., Murk J. L., Weening J. J., van der Poll T., Dankert J. Enhanced susceptibility to subcutaneous abscess formation and persistent infection around catheters is associated with sustained interleukin-1beta levels Infection and immunity 2000;68 (3):1692-1695 [PubMed]
  • Juffermans N. P., Dekkers P. E., Peppelenbosch M. P., Speelman P., van Deventer S. J., van der Poll T. Expression of the chemokine receptors CXCR1 and CXCR2 on granulocytes in human endotoxemia and tuberculosis: involvement of the p38 mitogen-activated protein kinase pathway Journal of infectious diseases 2000;182 (3):888-894 [PubMed]
  • Dekkers P. E., Juffermans N. P., Hove T. t, de Jonge E., van Deventer S. J., van der Poll T. Granulocyte colony-stimulating factor receptors on granulocytes are down-regulated after endotoxin administration to healthy humans Journal of infectious diseases 2000;181 (6):2067-2070 [PubMed]
  • Boelens J. J., van der Poll T., Dankert J., Zaat S. A. Interferon-gamma protects against biomaterial-associated Staphylococcus epidermidis infection in mice Journal of infectious diseases 2000;181 (3):1167-1171 [PubMed]
  • Olszyna D. P., Pajkrt D., Lauw F. N., van Deventer S. J., van der Poll T. Interleukin 10 inhibits the release of CC chemokines during human endotoxemia Journal of infectious diseases 2000;181 (2):613-620 [PubMed]
  • Boelens J. J., van der Poll T., Zaat S. A., Murk J. L., Weening J. J., Dankert J. Interleukin-1 receptor type I gene-deficient mice are less susceptible to Staphylococcus epidermidis biomaterial-associated infection than are wild-type mice Infection and immunity 2000;68 (12):6924-6931 [PubMed]
  • Juffermans N. P., Florquin S., Camoglio L., Verbon A., Kolk A. H., Speelman P., van Deventer S. J., van der Poll T. Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis Journal of infectious diseases 2000;182 (3):902-908 [PubMed]
  • Schultz M. J., Speelman P., Hack C. E., Buurman W. A., van Deventer S. J., van der Poll T. Intravenous infusion of erythromycin inhibits CXC chemokine production, but augments neutrophil degranulation in whole blood stimulated with Streptococcus pneumoniae Journal of antimicrobial chemotherapy 2000;46 (2):235-240 [PubMed]
  • Juffermans N. P., Verbon A., Belisle J. T., Hill P. J., Speelman P., van Deventer S. J., van der Poll T. Mycobacterial lipoarabinomannan induces an inflammatory response in the mouse lung. A role for interleukin-1 American journal of respiratory and critical care medicine 2000;162 (2 Part 1):486-489 [PubMed]
  • Levi M. [=Marcel M.], de Jonge E., van der Poll T., ten Cate H. Novel approaches to the management of disseminated intravascular coagulation Critical care medicine 2000;28 (9 Suppl):S20-S24 [PubMed]
  • Lauw F. N., Pajkrt D., Hack C. E., Kurimoto M., van Deventer S. J., van der Poll T. Proinflammatory effects of IL-10 during human endotoxemia Journal of immunology (Baltimore, Md. 2000;165 (5):2783-2789 [PubMed]
  • Schultz M. J., Olszyna D. P., de Jonge E., Verbon A., van Deventer S. J., van der Poll T. Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin Journal of infectious diseases 2000;182 (4):1264-1267 [PubMed]
  • Lauw F. N., ten Hove T., Dekkers P. E., de Jonge E., van Deventer S. J., van der Poll T. Reduced Th1, but not Th2, cytokine production by lymphocytes after in vivo exposure of healthy subjects to endotoxin Infection and immunity 2000;68 (3):1014-1018 [PubMed]
  • Lauw F. N., Simpson A. J., Hack C. E., Prins J. M., Wolbink A. M., van Deventer S. J., Chaowagul W., White N. J., van der Poll T. Soluble granzymes are released during human endotoxemia and in patients with severe infection due to gram-negative bacteria Journal of infectious diseases 2000;182 (1):206-213 [PubMed]
  • Juffermans N. P., Verbon A., Olszyna D. P., van Deventer S. J., Speelman P., van der Poll T. Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans Journal of infectious diseases 2000;181 (5):1813-1816 [PubMed]
  • Lauw F. N., Simpson A. J., Prins J. M., van Deventer S. J., Chaowagul W., White N. J., van der Poll T. The CXC chemokines gamma interferon (IFN-gamma)-inducible protein 10 and monokine induced by IFN-gamma are released during severe melioidosis Infection and immunity 2000;68 (7):3888-3893 [PubMed]
  • Schultz M. J., Speelman P., Zaat S. A., Hack C. E., van Deventer S. J., van der Poll T. The effect of pseudomonas exotoxin A on cytokine production in whole blood exposed to Pseudomonas aeruginosa FEMS immunology and medical microbiology 2000;29 (3):227-232 [PubMed]
  • Franco R. F., de Jonge E., Dekkers P. E., Timmerman J. J., Spek C. A., van Deventer S. J., van Deursen P., van Kerkhoff L., van Gemen B., ten Cate H., van der Poll T., Reitsma P. H. The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation Blood 2000;96 (2):554-559 [PubMed]
  • Dekkers P. E., ten Hove T., Lauw F. N., Koene H. R., Lumley P., van Deventer S. J., van der Poll T. The metalloproteinase inhibitor GI5402 inhibits endotoxin-induced soluble CD27 and CD16 release in healthy humans Infection and immunity 2000;68 (5):3036-3039 [PubMed]
  • van der Poll T. The use of granulocyte colony-stimulating factor in critically ill patients Critical care medicine 2000;28 (11):3758-3759 [PubMed]
  • de Jonge E., Dekkers P. E., Creasey A. A., Hack C. E., Paulson S. K., Karim A., Kesecioglu J., Levi M. [=Marcel M.], van Deventer S. J., van der Poll T. Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia Blood 2000;95 (4):1124-1129 [PubMed]
  • Juffermans N. P., Paxton W. A., Dekkers P. E., Verbon A., de Jonge E., Speelman P., van Deventer S. J., van der Poll T. Up-regulation of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells during human endotoxemia and after stimulation with (myco)bacterial antigens: the role of cytokines Blood 2000;96 (8):2649-2654 [PubMed]
  • Dekkers P. E., ten Hove T., te Velde A. A., van Deventer S. J., van der Poll T. Upregulation of monocyte urokinase plasminogen activator receptor during human endotoxemia Infection and immunity 2000;68 (4):2156-2160 [PubMed]

1999

  • Lauw F. N., te Velde A. A., Dekkers P. E., Speelman P., Aerts J. M., Hack C. E., van Deventer S. J., van der Poll T. Activation of mononuclear cells by interleukin-12: an in vivo study in chimpanzees Journal of clinical immunology 1999;19 (4):231-238 [PubMed]
  • van der Poll T., van Deventer S. J. Cytokines and anticytokines in the pathogenesis of sepsis Infectious disease clinics of North America 1999;13 (2):413-26, ix [PubMed]
  • Schultz M. J., Rijneveld A. W., Van Deventer S. J.H., Van Der Poll T. Cytokines and host defense in pneumonia Intensivmedizin und Notfallmedizin 1999;36 (3):270-275
  • Levi M. [=Marcel M.], de Jonge E., van der Poll T., ten Cate H. Disseminated intravascular coagulation Thrombosis and haemostasis 1999;82 (2):695-705 [PubMed]
  • Dekkers P. E., Levi M. [=Marcel M.], van Deventer S. J., van der Poll T. Divergent roles of tumor necrosis factor and platelet-activating factor in endotoxin-induced release of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta in chimpanzees Infection and immunity 1999;67 (10):5480-5482 [PubMed]
  • Juffermans N. P., Verbon A., van Deventer S. J., van Deutekom H., Belisle J. T., Ellis M. E., Speelman P., van der Poll T. Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan Infection and immunity 1999;67 (8):4295-4297 [PubMed]
  • Lauw F. N., Simpson A. J., Prins J. M., Smith M. D., Kurimoto M., van Deventer S. J., Speelman P., Chaowagul W., White N. J., van der Poll T. Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis Journal of infectious diseases 1999;180 (6):1878-1885 [PubMed]
  • Lauw F. N., Dekkers P. E., te Velde A. A., Speelman P., Levi M. [=Marcel M.], Kurimoto M., Hack C. E., van Deventer S. J., van der Poll T. Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees Journal of infectious diseases 1999;179 (3):646-652 [PubMed]
  • van Helvoort A., de Brouwer A., Ottenhoff R., Brouwers J. F., Wijnholds J., Beijnen J. H., Rijneveld A., van der Poll T., van der Valk M. A., Majoor D., Voorhout W., Wirtz K. W., Elferink R. P., Borst P. Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces Proceedings of the National Academy of Sciences of the United States of America 1999;96 (20):11501-11506 [PubMed]
  • van der Poll T., Endert E., Coyle S. M., Agosti J. M., Lowry S. F. Neutralization of TNF does not influence endotoxininduced changes in thyroid hormone metabolism in humans American journal of physiology 1999;276 (2 Part 2):R357-R362 [PubMed]
  • Van Der Poll Tom, De Jonge Evert, Levi Marcel, Van Deventer Sander J.H. Pathogenesis of DIC in sepsis Sepsis 1999;3 (2):103-109
  • Levi Marcel, Van Der Poll Tom, De Jonge Evert, Ten Cate Hugo Relative insufficiency of the fibrinolytic system in disseminated intravascular coagulation Sepsis 1999;3 (2):119-124
  • Hack C. E., Van der Poll T., Thijs L. G. Sepsis and coagulation Sepsis 1999;3 (2):85
  • Olszyna D. P., Prins J. M., Dekkers P. E., de Jonge E., Speelman P., van Deventer S. J., van der Poll T. Sequential measurements of chemokines in urosepsis and experimental endotoxemia Journal of clinical immunology 1999;19 (6):399-405 [PubMed]
  • Verbon A., Juffermans N., van Deventer S. J., Speelman P., van Deutekom H., van der Poll T. Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment Clinical and experimental immunology 1999;115 (1):110-113 [PubMed]
  • Dekkers P. E., Lauw F. N., ten Hove T., te Velde A. A., Lumley P., Becherer D., van Deventer S. J., van der Poll T. The effect of a metalloproteinase inhibitor (GI5402) on tumor necrosis factor-alpha (TNF-alpha) and TNF-alpha receptors during human endotoxemia Blood 1999;94 (7):2252-2258 [PubMed]

1998

  • Levi M. [=Marcel M.], van der Poll T., ten Cate H., Kuipers B., Biemond B. J., Jansen H. M., ten Cate J. W. Differential effects of anti-cytokine treatment on bronchoalveolar hemostasis in endotoxemic chimpanzees American journal of respiratory and critical care medicine 1998;158 (1):92-98 [PubMed]
  • Schultz M. J., Speelman P., Zaat S., van Deventer S. J., van der Poll T. Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood Antimicrobial agents and chemotherapy 1998;42 (7):1605-1609 [PubMed]
  • van der Poll T., Speelman P., van Deventer S. J. Immunologie in de medische praktijk. VIII. De rol van cytokinen in de pathogenese van bacteriële infectieziekten Nederlands tijdschrift voor geneeskunde 1998;142 (1):14-17 [PubMed]
  • Olszyna D. P., Prins J. M., Buis B., van Deventer S. J., Speelman P., van der Poll T. Levels of inhibitors of tumor necrosis factor alpha and interleukin 1beta in urine and sera of patients with urosepsis Infection and immunity 1998;66 (8):3527-3534 [PubMed]
  • Lemaire L. C., van Lanschot J. J., van der Poll T., Buurman W. A., van Deventer S. J., Gouma D. J. Lymph of patients with a systemic inflammatory response syndrome inhibits lipopolysaccharide-induced cytokine production Journal of infectious diseases 1998;178 (3):883-886 [PubMed]
  • Lemaire L. C., van der Poll T., van Lanschot J. J., Endert E., Buurman W. A., van Deventer S. J., Gouma D. J. Minimally invasive surgery induces endotoxin-tolerance in the absence of detectable endotoxemia Journal of clinical immunology 1998;18 (6):414-420 [PubMed]
  • van der Poll T., Levi M. [=Marcel M.], Braxton C. C., Coyle S. M., Roth M., ten Cate J. W., Lowry S. F. Parenteral nutrition facilitates activation of coagulation but not of fibrinolysis during human endotoxemia Journal of infectious diseases 1998;177 (3):793-795 [PubMed]
  • van Berge Henegouwen M. I., van der Poll T., van Deventer S. J., Gouma D. J. Peritoneal cytokine release after elective gastrointestinal surgery and postoperative complications American journal of surgery 1998;175 (4):311-316 [PubMed]
  • van Dullemen H. M., Wolbink G. J., Wever P. C., van der Poll T., Hack C. E., Tytgat G. N., van Deventer S. J. Reduction of circulating secretory phospholipase A2 levels by anti-tumor necrosis factor chimeric monoclonal antibody in patients with severe Crohn's disease. Relation between tumor necrosis factor and secretory phospholipase A2 in healthy humans and in active Crohn's disease Scandinavian journal of gastroenterology 1998;33 (10):1094-1098 [PubMed]
  • Juffermans N. P., Verbon A., van Deventer S. J., Buurman W. A., van Deutekom H., Speelman P., van der Poll T. Serum concentrations of lipopolysaccharide activity-modulating proteins during tuberculosis Journal of infectious diseases 1998;178 (6):1839-1842 [PubMed]
  • van der Poll T., van Deventer S. J. The role of interleukin 6 in endotoxin-induced inflammatory responses Progress in clinical and biological research 1998;397:365-377 [PubMed]
  • Juffermans N. P., Verbon A., Van Deventer S. J.H., Van Deutekom H., Speelman P., Van Der Poll T. Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis Pneumologie (Stuttgart, Germany) 1998;52 (11):625
  • Juffermans N. P., Verbon A., van Deventer S. J., van Deutekom H., Speelman P., van der Poll T. Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis American journal of respiratory and critical care medicine 1998;157 (4 Part 1):1328-1331 [PubMed]

1997

  • van der Poll T., de Waal Malefyt R., Coyle S. M., Lowry S. F. Antiinflammatory cytokine responses during clinical sepsis and experimental endotoxemia: sequential measurements of plasma soluble interleukin (IL)-1 receptor type II, IL-10, and IL-13 Journal of infectious diseases 1997;175 (1):118-122 [PubMed]
  • Pajkrt D., Camoglio L., Tiel-van Buul M. C., de Bruin K., Cutler D. L., Affrime M. B., Rikken G., van der Poll T., ten Cate J. W., van Deventer S. J. Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration Journal of immunology (Baltimore, Md. 1997;158 (8):3971-3977 [PubMed]
  • ten Cate J. W., van der Poll T., Levi M. [=Marcel M.], ten Cate H., van Deventer S. J. Cytokines: triggers of clinical thrombotic disease Thrombosis and haemostasis 1997;78 (1):415-419 [PubMed]
  • Pajkrt D., Lerch P. G., van der Poll T., Levi M. [=Marcel M.], Illi M., Doran J. E., Arnet B., van den Ende A., ten Cate J. W., van Deventer S. J. Differential effects of reconstituted high-density lipoprotein on coagulation, fibrinolysis and platelet activation during human endotoxemia Thrombosis and haemostasis 1997;77 (2):303-307 [PubMed]
  • van der Poll T., Coyle S. M., Kumar A., Barbosa K., Agosti J. M., Lowry S. F. Down-regulation of surface receptors for TNF and IL-1 on circulating monocytes and granulocytes during human endotoxemia: effect of neutralization of endotoxin-induced TNF activity by infusion of a recombinant dimeric TNF receptor Journal of immunology (Baltimore, Md. 1997;158 (3):1490-1497 [PubMed]
  • van der Poll T., Coyle S. M., Levi M. [=Marcel M.], Jansen P. M., Dentener M., Barbosa K., Buurman W. A., Hack C. E., ten Cate J. W., Agosti J. M., Lowry S. F. Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans Blood 1997;89 (10):3727-3734 [PubMed]
  • van der Poll T., Jansen P. M., Montegut W. J., Braxton C. C., Calvano S. E., Stackpole S. A., Smith S. R., Swanson S. W., Hack C. E., Lowry S. F., Moldawer L. L. Effects of IL-10 on systemic inflammatory responses during sublethal primate endotoxemia Journal of immunology (Baltimore, Md. 1997;158 (4):1971-1975 [PubMed]
  • van der Poll T., Calvano S. E., Kumar A., Coyle S. M., Lowry S. F. Epinephrine attenuates down-regulation of monocyte tumor necrosis factor receptors during human endotoxemia Journal of leukocyte biology 1997;61 (2):156-160 [PubMed]
  • van der Poll T., Levi M. [=Marcel M.], Dentener M., Jansen P. M., Coyle S. M., Braxton C. C., Buurman W. A., Hack C. E., ten Cate J. W., Lowry S. F. Epinephrine exerts anticoagulant effects during human endotoxemia Journal of experimental medicine 1997;185 (6):1143-1148 [PubMed]
  • van der Poll T., Lowry S. F. Epinephrine inhibits endotoxin-induced IL-1 beta production: roles of tumor necrosis factor-alpha and IL-10 American journal of physiology 1997;273 (6 Part 2):R1885-R1890 [PubMed]
  • Lemaire L. C.J.M., Van Der Poll T., Van Lanschot J. J.B., Levels H. M., Van Der Ende B., Van Deventer S. J.H., Gouma D. J. Human thoracic duct lymph inhibits lipopolysaccharide-induced release of cytokines Innate immunity 1997;4 (5):331-338
  • Pajkrt D., van der Poll T., Levi M. [=Marcel M.], Cutler D. L., Affrime M. B., van den Ende A., ten Cate J. W., van Deventer S. J. Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia Blood 1997;89 (8):2701-2705 [PubMed]
  • van der Poll T., Keogh C. V., Guirao X., Buurman W. A., Kopf M., Lowry S. F. Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia Journal of infectious diseases 1997;176 (2):439-444 [PubMed]
  • van der Poll T., Lowry S. F. Lipopolysaccharide-induced interleukin 8 production by human whole blood is enhanced by epinephrine and inhibited by hydrocortisone Infection and immunity 1997;65 (6):2378-2381 [PubMed]
  • Pajkrt D., Manten A., van der Poll T., Tiel-van Buul M. M., Jansen J., ten Cate J. Wouter, van Deventer S. J. Modulation of cytokine release and neutrophil function by granulocyte colony-stimulating factor during endotoxemia in humans Blood 1997;90 (4):1415-1424 [PubMed]
  • van der Poll T., Keogh C. V., Buurman W. A., Lowry S. F. Passive immunization against tumor necrosis factor-alpha impairs host defense during pneumococcal pneumonia in mice American journal of respiratory and critical care medicine 1997;155 (2):603-608 [PubMed]
  • van der Poll T., Jansen P. M., van Zee K. J., Hack C. E., Oldenburg H. A., Loetscher H., Lesslauer W., Lowry S. F., Moldawer L. L. Pretreatment with a 55-kDa tumor necrosis factor receptor-immunoglobulin fusion protein attenuates activation of coagulation, but not of fibrinolysis, during lethal bacteremia in baboons Journal of infectious diseases 1997;176 (1):296-299 [PubMed]
  • Levi M. [=Marcel M.], van der Poll T., ten Cate H., van Deventer S. J. The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia European journal of clinical investigation 1997;27 (1):3-9 [PubMed]
  • Van der Poll T., Marchant A., Van Deventer S. J.H. The role of interleukin-10 in the pathogenesis of bacterial infection Clinical microbiology and infection 1997;3 (6):605-607

1996

  • Pajkrt D., Doran J. E., Koster F., Lerch P. G., Arnet B., van der Poll T., ten Cate J. W., van Deventer S. J. Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia Journal of experimental medicine 1996;184 (5):1601-1608 [PubMed]
  • van der Poll T., Coyle S. M., Moldawer L. L., Lowry S. F. Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin Journal of infectious diseases 1996;174 (6):1356-1360 [PubMed]
  • Van Der Poll Tom, Van Deventer Sander J.h. Editorial Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: The role of tumour necrosis factor-α in sepsis revisited: From good, to bad, to worse Expert opinion on investigational drugs 1996;5 (7):805-807
  • van der Poll T., Keogh C. V., Helfgott D., Berman L., Buurman W. A., Lowry S. F. Effects of anti-interleukin 6 on inflammatory responses during murine septic peritonitis Innate immunity 1996;3 (6):463-470
  • Van Der Poll T., Keogh C. V., Helfgott D., Berman L., Buurman W. A., Lowry S. F. Effects of anti-interleukin 6 on inflammatory responses during murine septic peritonitis Journal of endotoxin research 1996;3 (6):463-470
  • van der Poll T., Coyle S. M., Barbosa K., Braxton C. C., Lowry S. F. Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia Journal of clinical investigation 1996;97 (3):713-719 [PubMed]
  • van der Poll T., Coyle S. M., Levi M. [=Marcel M.], Boermeester M. A., Braxton C. C., Jansen P. M., Hack C. E., Lowry S. F. Fat emulsion infusion potentiates coagulation activation during human endotoxemia Thrombosis and haemostasis 1996;75 (1):83-86 [PubMed]
  • van der Poll T., Barber A. E., Coyle S. M., Lowry S. F. Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia--a clinical research center study Journal of clinical endocrinology and metabolism 1996;81 (10):3604-3606 [PubMed]
  • van der Poll T., Marchant A., Keogh C. V., Goldman M., Lowry S. F. Interleukin-10 impairs host defense in murine pneumococcal pneumonia Journal of infectious diseases 1996;174 (5):994-1000 [PubMed]
  • van der Poll T., Jansen J., Levi M. [=Marcel M.], ten Cate H., Hack C. E., Aarden L. A., ten Cate J. W., van Deventer S. J. Interleukin 10 release during endotoxaemia in chimpanzees: role of platelet-activating factor and interleukin 6 Scandinavian journal of immunology 1996;43 (1):122-125 [PubMed]
  • Stouthard J. M., Levi M. [=Marcel M.], Hack C. E., Veenhof C. H., Romijn H. A., Sauerwein H. P., van der Poll T. Interleukin-6 stimulates coagulation, not fibrinolysis, in humans Thrombosis and haemostasis 1996;76 (5):738-742 [PubMed]
  • Calvano S. E., van der Poll T., Coyle S. M., Barie P. S., Moldawer L. L., Lowry S. F. Monocyte tumor necrosis factor receptor levels as a predictor of risk in human sepsis Archives of surgery (Chicago, Ill. 1996;131 (4):434-437 [PubMed]
  • von der Möhlen M. A., van der Poll T., Jansen J., Levi M. [=Marcel M.], van Deventer S. J. Release of bactericidal/permeability-increasing protein in experimental endotoxemia and clinical sepsis. Role of tumor necrosis factor Journal of immunology (Baltimore, Md. 1996;156 (12):4969-4973 [PubMed]
  • Levi M., Van Der Poll T., Btemond B. J., Ten Gate H., Kuipers B., Ten Gate J. W. Tnf-dependkm depression of bronchoalveolar fibrinolysis as pathogknetic mechanism of ards in experimental endotoxemia in chimpanzees FIBRINOLYSIS & PROTEOLYSIS 1996;10 (SUPPL. 3):71
  • van der Poll T., Jansen P. M., van Zee K. J., Welborn M. B., de Jong I., Hack C. E., Loetscher H., Lesslauer W., Lowry S. F., Moldawer L. L. Tumor necrosis factor-alpha induces activation of coagulation and fibrinolysis in baboons through an exclusive effect on the p55 receptor Blood 1996;88 (3):922-927 [PubMed]

1995

  • Biemond B. J., Levi M. [=Marcel M.], ten Cate H., Soule H. R., Morris L. D., Foster D. L., Bogowitz C. A., van der Poll T., Büller H. R., ten Cate J. W. Complete inhibition of endotoxin-induced coagulation activation in chimpanzees with a monoclonal Fab fragment against factor VII/VIIa Thrombosis and haemostasis 1995;73 (2):223-230 [PubMed]
  • Jansen P. M., Boermeester M. A., Fischer E., de Jong I. W., van der Poll T., Moldawer L. L., Hack C. E., Lowry S. F. Contribution of interleukin-1 to activation of coagulation and fibrinolysis, neutrophil degranulation, and the release of secretory-type phospholipase A2 in sepsis: studies in nonhuman primates after interleukin-1 alpha administration and during lethal bacteremia Blood 1995;86 (3):1027-1034 [PubMed]
  • van der Poll T., Braxton C. C., Coyle S. M., Boermeester M. A., Wang J. C., Jansen P. M., Montegut W. J., Calvano S. E., Hack C. E., Lowry S. F. Effect of hypertriglyceridemia on endotoxin responsiveness in humans Infection and immunity 1995;63 (9):3396-3400 [PubMed]
  • van der Poll T., Levi M. [=Marcel M.], ten Cate H., Jansen J., Biemond B. J., Haagmans B. L., Eerenberg A., van Deventer S. J., Hack C. E., ten Cate J. W. Effect of postponed treatment with an anti-tumour necrosis factor (TNF) F(ab')2 fragment on endotoxin-induced cytokine and neutrophil responses in chimpanzees Clinical and experimental immunology 1995;100 (1):21-25 [PubMed]
  • Stouthard J. M., Romijn J. A., van der Poll T., Endert E., Klein S., Bakker P. J., Veenhof C. H., Sauerwein H. P. Endocrinologic and metabolic effects of interleukin-6 in humans American journal of physiology 1995;268 (5 Part 1):E813-E819 [PubMed]
  • van der Poll T., Marchant A., Buurman W. A., Berman L., Keogh C. V., Lazarus D. D., Nguyen L., Goldman M., Moldawer L. L., Lowry S. F. Endogenous IL-10 protects mice from death during septic peritonitis Journal of immunology (Baltimore, Md. 1995;155 (11):5397-5401 [PubMed]
  • van der Poll T., Calvano S. E., Kumar A., Braxton C. C., Coyle S. M., Barbosa K., Moldawer L. L., Lowry S. F. Endotoxin induces downregulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans Blood 1995;86 (7):2754-2759 [PubMed]
  • Barber A. E., Coyle S. M., Fischer E., Smith C., van der Poll T., Shires G. T., Lowry S. F. Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings Surgery 1995;118 (2):406-10; discussion 410-1 [PubMed]
  • Jansen J., van der Poll T., Levi M. [=Marcel M.], ten Cate H., Gallati H., ten Cate J. W., van Deventer S. J. Inhibition of the release of soluble tumor necrosis factor receptors in experimental endotoxemia by an anti-tumor necrosis factor-alpha antibody Journal of clinical immunology 1995;15 (1):45-50 [PubMed]
  • van der Poll T., Fischer E., Coyle S. M., van Zee K. J., Pribble J. P., Stiles D. M., Barie P. S., Buurman W. A., Moldawer L. L., Lowry S. F. Interleukin-1 contributes to increased concentrations of soluble tumor necrosis factor receptor type I in sepsis Journal of infectious diseases 1995;172 (2):577-580 [PubMed]
  • van der Poll T., van Zee K. J., Endert E., Coyle S. M., Stiles D. M., Pribble J. P., Catalano M. A., Moldawer L. L., Lowry S. F. Interleukin-1 receptor blockade does not affect endotoxin-induced changes in plasma thyroid hormone and thyrotropin concentrations in man Journal of clinical endocrinology and metabolism 1995;80 (4):1341-1346 [PubMed]
  • van der Poll T., Zijlstra E. E., Mevissen M. Interleukin 6 during active visceral leishmaniasis and after treatment Clinical immunology and immunopathology 1995;77 (1):111-114 [PubMed]
  • Braxton C. C., Coyle S. M., Montegut W. J., van der Poll T., Roth M., Calvano S. E., Lowry S. F. Parenteral nutrition alters monocyte TNF receptor activity Journal of surgical research 1995;59 (1):23-28 [PubMed]
  • Biemond B. J., Levi M. [=Marcel M.], ten Cate H., van der Poll T., Büller H. R., Hack C. E., ten Cate J. W. Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of interventions in the cytokine and coagulation cascades Clinical science (London, England 1995;88 (5):587-594 [PubMed]
  • Godfried M. H., Romijn J. A., van der Poll T., Weverling G. J., Corssmit E. P., Endert E., Eeftinck Schattenkerk J. K., Sauerwein H. P. Soluble receptors for tumor necrosis factor are markers for clinical course but not for major metabolic changes in human immunodeficiency virus infection Metabolism: clinical and experimental 1995;44 (12):1564-1569 [PubMed]
  • Zijlstra E. E., van der Poll T., Mevissen M. Soluble receptors for tumor necrosis factor as markers of disease activity in visceral leishmaniasis Journal of infectious diseases 1995;171 (2):498-501 [PubMed]
  • Godfried M. H., van der Poll T., Mulder J. W., Weverling G. J., Endert E., Lange J. M., Sauerwein H. P. Soluble tumor necrosis factor receptors as surrogate markers for the assessment of zidovudine treatment in asymptomatic HIV-1 infection Journal of acquired immune deficiency syndromes and human retrovirology 1995;10 (5):531-539 [PubMed]
  • van der Poll T., Lowry S. F. Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense? Shock (Augusta, Ga.) 1995;3 (1):1-12 [PubMed]

1994

  • Dondorp A. M., Veenstra J., van der Poll T., Mulder J. W., Reiss P. Activation of the cytokine network in a patient with AIDS and the recalcitrant erythematous desquamating disorder Clinical infectious diseases 1994;18 (6):942-945 [PubMed]
  • ten Cate H., Schenk B. E., Biemond B. J., Levi M. [=Marcel M.], van der Poll T., Buller H. R., ten Cate J. W. A review of studies of the activation of the blood coagulation mechanism in chimpanzees (Pan troglodytes) Journal of medical primatology 1994;23 (5):280-284 [PubMed]
  • van der Poll T., Levi M. [=Marcel M.], van Deventer S. J., ten Cate H., Haagmans B. L., Biemond B. J., Büller H. R., Hack C. E., ten Cate J. W. Differential effects of anti-tumor necrosis factor monoclonal antibodies on systemic inflammatory responses in experimental endotoxemia in chimpanzees Blood 1994;83 (2):446-451 [PubMed]
  • Stouthard J. M., van der Poll T., Endert E., Bakker P. J., Veenhof C. H., Sauerwein H. P., Romijn J. A. Effects of acute and chronic interleukin-6 administration on thyroid hormone metabolism in humans Journal of clinical endocrinology and metabolism 1994;79 (5):1342-1346 [PubMed]
  • van der Poll T., Levi M. [=Marcel M.], Hack C. E., ten Cate H., van Deventer S. J., Eerenberg A. J., de Groot E. R., Jansen J., Gallati H., Büller H. R. Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees Journal of experimental medicine 1994;179 (4):1253-1259 [PubMed]
  • Jansen J., van der Poll T., van Deventer S. J. Endotoxin and the release of tumor necrosis factor receptors. Progress in clinical and biological research 1994;388:383-397 [PubMed]
  • Bemelman F. J., Jansen J., van der Poll T., Hack C. E., van Deventer S. J., ten Berge R. J. Increased levels of sTNF receptors following OKT3 treatment Transplantation proceedings 1994;26 (6):3094-3095 [PubMed]
  • Bemelman F. J., Jansen J., van der Poll T., van Deventer S. J., ten Berge R. J. Increase of sTNF receptor levels in acute renal allograft rejection after treatment with OKT3 Nephrology, dialysis, transplantation 1994;9 (12):1786-1790 [PubMed]
  • Levi M. [=Marcel M.], ten Cate H., Bauer K. A., van der Poll T., Edgington T. S., Büller H. R., van Deventer S. J., Hack C. E., ten Cate J. W., Rosenberg R. D. Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees Journal of clinical investigation 1994;93 (1):114-120 [PubMed]
  • ten Cate H., Levi M. [=Marcel M.], van der Poll T., Biemond B. J., van Deventer S. J., Buller H. R., ten Cate J. W. Inhibition of extrinsic coagulation activation in endotoxemia; therapeutic implications Progress in clinical and biological research 1994;388:215-219 [PubMed]
  • Koopmans R., Hoek F. J., van Deventer S. J., van der Poll T. Model for whole body production of tumour necrosis factor-alpha in experimental endotoxaemia in healthy subjects Clinical science (London, England 1994;87 (4):459-465 [PubMed]
  • van der Poll T., Jansen J., Endert E., Sauerwein H. P., van Deventer S. J. Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood Infection and immunity 1994;62 (5):2046-2050 [PubMed]
  • Kuipers B., van der Poll T., Levi M. [=Marcel M.], van Deventer S. J., ten Cate H., Imai Y., Hack C. E., ten Cate J. W. Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees Journal of immunology (Baltimore, Md. 1994;152 (5):2438-2446 [PubMed]
  • van der Poll T., Jansen J., Levi M. [=Marcel M.], ten Cate H., ten Cate J. W., van Deventer S. J. Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees Journal of experimental medicine 1994;180 (5):1985-1988 [PubMed]
  • Godfried M. H., van der Poll T., Weverling G. J., Mulder J. W., Jansen J., van Deventer S. J., Sauerwein H. P. Soluble receptors for tumor necrosis factor as predictors of progression to AIDS in asymptomatic human immunodeficiency virus type 1 infection Journal of infectious diseases 1994;169 (4):739-745 [PubMed]
  • van der Poll T., Levi M., ten Cate H., van Deventer S. J. The role of tumor necrosis factor in systemic inflammatory responses in primate endotoxemia. Progress in clinical and biological research 1994;388:425-433 [PubMed]
  • van der Poll T., van Deventer S. J., ten Cate H., Levi M. [=Marcel M.], ten Cate J. W. Tumor necrosis factor is involved in the appearance of interleukin-1 receptor antagonist in endotoxemia Journal of infectious diseases 1994;169 (3):665-667 [PubMed]

1993

  • van der Poll T., Romijn J. A., Endert E., Sauerwein H. P. Effects of tumor necrosis factor on the hypothalamic-pituitary-testicular axis in healthy men Metabolism: clinical and experimental 1993;42 (3):303-307 [PubMed]
  • van Deventer S. J., Hart M., van der Poll T., Hack C. E., Aarden L. A. Endotoxin and tumor necrosis factor-alpha-induced interleukin-8 release in humans Journal of infectious diseases 1993;167 (2):461-454 [PubMed]
  • Portegies P., Godfried M. H., Hintzen R. Q., Stam J., van der Poll T., Bakker M., van Deventer S. J., van Lier R. A., Goudsmit J. Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex Journal of neuroimmunology 1993;48 (2):241-247 [PubMed]
  • Levi M. [=Marcel M.], ten Cate H., van der Poll T., van Deventer S. J. Pathogenesis of disseminated intravascular coagulation in sepsis JAMA 1993;270 (8):975-979 [PubMed]
  • van Leenen D., van der Poll T., Levi M. [=Marcel M.], ten Cate H., van Deventer S. J., Hack C. E., Aarden L. A., ten Cate J. W. Pentoxifylline attenuates neutrophil activation in experimental endotoxemia in chimpanzees Journal of immunology (Baltimore, Md. 1993;151 (4):2318-2325 [PubMed]
  • van der Poll T., Jansen J., van Leenen D., von der Möhlen M., Levi M. [=Marcel M.], ten Cate H., Gallati H., ten Cate J. W., van Deventer S. J. Release of soluble receptors for tumor necrosis factor in clinical sepsis and experimental endotoxemia Journal of infectious diseases 1993;168 (4):955-960 [PubMed]
  • Godfried M. H., van der Poll T., Jansen J., Romijin J. A., Schattenkerk J. K., Endert E., van Deventer S. J., Sauerwein H. P. Soluble receptors for tumour necrosis factor: a putative marker of disease progression in HIV infection AIDS (London, England) 1993;7 (1):33-36 [PubMed]
  • van der Poll T., Sauerwein H. P. Tumour necrosis factor-alpha: its role in the metabolic response to sepsis Clinical science (London, England 1993;84 (3):247-256 [PubMed]

1992

  • Van der Poll T. Cytokines and their inhibition in septicaemia: The role of three major cytokines in the pathogenesis of septicaemia British Journal of Intensive Care 1992;2 (2):99-100+102+104
  • van der Poll T., van Deventer S. J., Hack C. E., Wolbink G. J., Aarden L. A., Büller H. R., ten Cate J. W. Effects on leukocytes after injection of tumor necrosis factor into healthy humans Blood 1992;79 (3):693-698 [PubMed]
  • van der Poll T., van Deventer S. J., Pasterkamp G., van Mourik J. A., Büller H. R., ten Cate J. W. Tumor necrosis factor induces von Willebrand factor release in healthy humans Thrombosis and haemostasis 1992;67 (6):623-626 [PubMed]

1991

  • van der Poll T., van Deventer S. J., Büller H. R., Sturk A., ten Cate J. W. Comparison of the early dynamics of coagulation activation after injection of endotoxin and tumor necrosis factor in healthy humans Progress in clinical and biological research 1991;367:55-60 [PubMed]
  • van der Poll T., van Deventer S. J., Büller H. R., Sturk A., ten Cate J. W. Comparison of the early dynamics of systemic prostacyclin release after administration of tumor necrosis factor and endotoxin to healthy humans Journal of infectious diseases 1991;164 (3):599-601 [PubMed]
  • van der Poll T., Levi M. [=Marcel M.], Büller H. R., van Deventer S. J., de Boer J. P., Hack C. E., ten Cate J. W. Fibrinolytic response to tumor necrosis factor in healthy subjects Journal of experimental medicine 1991;174 (3):729-732 [PubMed]
  • van der Poll T., Romijn J. A., Endert E., Borm J. J., Büller H. R., Sauerwein H. P. Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans American journal of physiology 1991;261 (4 Part 1):E457-E465 [PubMed]

1990

  • van der Poll T., Büller H. R., ten Cate H., Wortel C. H., Bauer K. A., van Deventer S. J., Hack C. E., Sauerwein H. P., Rosenberg R. D., ten Cate J. W. Activation of coagulation after administration of tumor necrosis factor to normal subjects New England journal of medicine 1990;322 (23):1622-1627 [PubMed]
  • Colman Robert W., Rosner Fred, Van Der Poll Tom, Büller Harry R., Ten Cate Jan W., Hack C. Erik Effect of tumor necrosis factor in normal subjects New England journal of medicine 1990;323 (19):1350-1352 [PubMed]
  • Van der Poll T., Buller H. R., Ten Cate J. W., Hack C. E. Effect of tumor necrosis factor in normal subjects (Reply) New England journal of medicine 1990;323 (19):1351-1352
  • van der Poll T., Romijn J. A., Wiersinga W. M., Sauerwein H. P. Tumor necrosis factor: a putative mediator of the sick euthyroid syndrome in man Journal of clinical endocrinology and metabolism 1990;71 (6):1567-1572 [PubMed]
back to Prof. PhD T. van der Poll