Prof. N.P. Juffermans MD PhD publications

2021

• Diephuis Eva C., de Borgie Corianne A., Zwinderman A., Winkelman Jacobus A., van Boven Wim-Jan P., Henriques José P. S., Eberl Susanne, Juffermans Nicole P., Schultz Marcus J., Klautz Robert J. M., Koolbergen David R. Continuous postoperative pericardial flushing reduces postoperative bleeding after coronary artery bypass grafting: A randomized trial EClinicalMedicine 2021;31 [PubMed]
• Vincent Jean-Louis, Wendon Julia, Martin Greg S., Juffermans Nicole P., Creteur Jacques, Cecconi Maurizio COVID-19: What we’ve done well and what we could or should have done better—the 4 Ps Critical care (London, England) 2021;25 (1) [PubMed]
• Simonis Fabienne D., Juffermans Nicole P., Schultz Marcus J. Mechanical ventilation of the healthy lungs: lessons learned from recent trials Current opinion in critical care 2021;27 (1):55-59 [PubMed]
• Baksaas-Aasen K., Gall L. S., Stensballe J., Juffermans N. P., Curry N., Maegele M., Brooks A., Rourke C., Gillespie S., Murphy J., Maroni R., Vulliamy P., Henriksen H. H., Pedersen K. Holst, Kolstadbraaten K. M., Wirtz M. R., Kleinveld D. J. B., Schäfer N., Chinna S., Davenport R. A., Naess P. A., Goslings J. C., Eaglestone S., Stanworth S., Johansson P. I., Gaarder C., Brohi K. Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial Intensive care medicine 2021;47 (1):49-59 [PubMed]

2020

• Carla Adrien, Pereira Bruno, Boukail Hanifa, Audard Jules, Pinol-Domenech Nathalie, de Carvalho Manuela, Blondonnet Raiko, Zhai Ruoyang, Morand Dominique, Lambert C. line, Sapin Vincent, Ware Lorraine B., Calfee Carolyn S., Bastarache Julie A., Laffey John G., Juffermans Nicole P., Bos Lieuwe D., Artigas Antonio, Rocco Patricia R. M., Matthay Michael A., McAuley Daniel F., Constantin Jean-Michel, Jabaudon Matthieu Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: Protocol for a systematic review and meta-analysis Respiratory research 2020;21 (1) [PubMed]
• Spaan I. T., van der Sluijs A. F., Boelens A. D., Binnekade J., van Lieshout E. J., Juffermans N. P., Mudde R., Bouter P., Dongelmans D. A., Vlaar A. P. J. A lean approach to improve the organisation of unplanned intensive care admissions: A before-after analysis Netherlands journal of critical care 2020;28 (3):134-138
• Juschten Jenny, Ingelse Sarah A, Bos Lieuwe D J, Girbes Armand R J, Juffermans Nicole P, van der Poll Tom, Schultz Marcus J, Tuinman Pieter Roel, Study group members AMC , Lagrand Wim K., Horn Johanna Alkaline phosphatase in pulmonary inflammation-a translational study in ventilated critically ill patients and rats Intensive Care Medicine Experimental 2020;8 (Suppl 1):46 [PubMed]
• Dujardin Romein W. G., Hilderink Bashar N., Haksteen Wolmet E., Middeldorp S., Vlaar Alexander P. J., Thachil J., Müller Marcella C. A., Juffermans Nicole P. Biomarkers for the prediction of venous thromboembolism in critically ill COVID-19 patients Thrombosis research 2020;196:308-312 [PubMed]
• Glas Gerie J., Horn Janneke, van der Hoeven Sophia M., Hollmann Markus W., Cleffken Berry, Colpaert Kirsten, Juffermans Nicole P., Knape Paul, Loef Bert G., Mackie David P., Malbrain Manu, Muller Jan, Reidinga Auke C., Preckel Benedikt, Schultz Marcus J. Changes in ventilator settings and ventilation–induced lung injury in burn patients—A systematic review Burns 2020;46 (4):762-770 [PubMed]
• Christiaans Clarissa A. M. Coagulopathy after adult and pediatric trauma 2020. 179p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Juffermans Nicole P., Pittet Jean-François; Co-supervisor: Goslings Johan C.)
• Diephuis Eva, de Borgie Corianne, Tomšič Anton, Winkelman Jacobus, van Boven Wim Jan, Bouma Berto, Eberl Susanne, Juffermans Nicole, Schultz Marcus, Henriques Jose P., Koolbergen David Continuous postoperative pericardial flushing method versus standard care for wound drainage after adult cardiac surgery: A randomized controlled trial EBioMedicine 2020;55 [PubMed]
• van Biesen Stefaan, Kwa David, Bosman Robert J., Juffermans Nicole P. Detection of invasive pulmonary aspergillosis in COVID-19 with Nondirected BAL American journal of respiratory and critical care medicine 2020;208 (8):1171-1173 [PubMed]
• van den Brink Daan P., Wirtz Mathijs R., Neto Ary Serpa, Schöchl Herbert, Viersen Victor, Binnekade Jan, Juffermans Nicole P. Effectiveness of prothrombin complex concentrate for the treatment of bleeding: A systematic review and meta-analysis Journal of thrombosis and haemostasis 2020;18 (10):2457-2467 [PubMed]
• van Hezel Maike E. Effect of red cell transfusion on the host immune response in critically ill patients 2020. 235p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Juffermans Nicole P., Schultz Marcus J.; Co-supervisor: van Bruggen R.)
• Vlaar Alexander P., Oczkowski Simon, Murphy Gavin J., Perner Anders, Guyatt Gordon, Dionne Joanna C., Cecconi Maurizio, de Bruin Sanne, Wijnberge Marije, Antonelli Massimo, Aubron Cecile, Aries Philippe, Duranteau Jacques, Juffermans Nicole P., Meier Jens, Abbasciano Riccardo, Muller Marcella, Shah Akshay, Rygaard Sofie, Walsh Timothy S. Guidelines seek unbiased recommendations Intensive care medicine 2020;46 (5):1065-1069 [PubMed]
• Thachil Jecko, Juffermans Nicole P., Ranucci Marco, Connors Jean M., Warkentin Theodore E., Ortel Thomas L., Levi Marcel, Iba Toshiaki, Levy Jerrold H. ISTH DIC subcommittee communication on anticoagulation in COVID-19 Journal of thrombosis and haemostasis 2020;18 (9):2138-2144 [PubMed]
• Robba Chiara, Poole Daniele, McNett Molly, Asehnoune Karim, Bösel Julian, Bruder Nicolas, Chieregato Arturo, Cinotti Raphael, Duranteau Jacques, Einav Sharon, Ercole Ari, Ferguson Niall, Guerin Claude, Siempos Ilias I., Kurtz Pedro, Juffermans Nicole P., Mancebo Jordi, Mascia Luciana, McCredie Victoria, Nin Nicolas, Oddo Mauro, Pelosi Paolo, Rabinstein Alejandro A., Neto Ary Serpa, Seder David B., Skrifvars Markus B., Suarez Jose I., Taccone Fabio Silvio, van der Jagt Mathieu, Citerio Giuseppe, Stevens Robert D. Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus Intensive care medicine 2020;46 (12):2397-2410 [PubMed]
• Harmon Matthew B. A., Hodiamont C. J., Dankiewicz Josef, Nielsen Niklas, Schultz Marcus J., Horn Janneke, Friberg Hans, Juffermans Nicole P. Microbiological profile of nosocomial infections following cardiac arrest: Insights from the targeted temperature management (TTM) trial Resuscitation 2020;148:227-233 [PubMed]
• Cherpanath Thomas G. V., Simonis Fabienne D., Bouma Berto J., de Bruin-Bon Rianne H., Determann Rogier M., Juffermans Nicole P., Abreu Marcelo Gama De, Pelosi Paolo, Neto Ary Serpa, Groeneveld Johan A. B., Schultz Marcus J., Lagrand Wim K. Myocardial Function during Low versus Intermediate Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome Anesthesiology 2020:1102-1113 [PubMed]
• Glas Gerie J, Horn Janneke, Binnekade Jan M, Hollmann Markus W, Muller Jan, Cleffken Berry, Colpaert Kirsten, Dixon Barry, Juffermans Nicole P, Knape Paul, Levi Marcel M, Loef Bert G, Mackie David P, Malbrain Manu L N G, Preckel Benedikt, Reidinga Auke C, van der Sluijs K F, Schultz Marcus J Nebulized Heparin in Burn Patients with Inhalation Trauma-Safety and Feasibility Journal of clinical medicine 2020;9 (4) [PubMed]
• Harmon Matthew B. A., Pelleboer Ineke, Steiner Alexandre A., Wiewel Maryse, Schultz Marcus J., Horn Janneke, Juffermans Nicole P. Opinions and Management of Hypothermic Sepsis: Results from an Online Survey Therapeutic hypothermia and temperature management 2020;10 (2):102-105 [PubMed]
• Krens Stefanie D., Hodiamont Caspar J., Juffermans Nicole P., Mathôt Ron A. A., van Hest Reinier M. Population Pharmacokinetics of Ganciclovir in Critically Ill Patients Therapeutic drug monitoring 2020;42 (2):295-301 [PubMed]
• Boshuizen Margit, Binnekade Jan M., Nota Benjamin, van de Groep Kirsten, Cremer Olaf L., Horn Janneke, Schultz Marcus J., van Bruggen Robin, Juffermans Nicole P. Potential of Parameters of Iron Metabolism for the Diagnosis of Anemia of Inflammation in the Critically Ill Transfusion medicine and hemotherapy 2020;47 (1):61-67 [PubMed]
• Wirtz Mathijs R., Almizraq Ruqayyah J., Weber Nina C., Norris Philip J., Pandey Suchitra, Spinella Philip C., Muszynski Jennifer A., P. Acker Jason, Juffermans Nicole P. Red-blood-cell manufacturing methods and storage solutions differentially induce pulmonary cell activation Vox sanguinis 2020;115 (5):395-404 [PubMed]
• van Hezel Maike E., Boshuizen Margit, Peters Anna L., Straat M., Vlaar Alexander P., Spoelstra - de Man Angelique M. E., Tanck Michael W. T., Tool Anton T. J., Beuger Boukje M., Kuijpers Taco W., Juffermans Nicole P., van Bruggen Robin Red blood cell transfusion results in adhesion of neutrophils in human endotoxemia and in critically ill patients with sepsis Transfusion 2020;60 (2):294-302 [PubMed]
• Nieuwenhuis Marieke B., van Biesen Stefaan, Juffermans Nicole P. Response to "co-infections in COVID-19 critically ill and antibiotic management: A prospective cohort analysis" Critical care (London, England) 2020;24 (1) [PubMed]
• van Manen Lisa, Deurvorst Jessica M., van Hezel Maike E., Boshuizen Margit, van Bruggen Robin, Juffermans Nicole P. Severity of illness influences the microcirculatory response to red blood cell transfusion in the critically ill: an observational cohort study Critical care (London, England) 2020;24 (1):498 [PubMed]
• Baysan Meryem, Arbous Mendi S., Mik Egbert G., Juffermans Nicole P., van der Bom Johanna G. Study protocol and pilot results of an observational cohort study evaluating effect of red blood cell transfusion on oxygenation and mitochondrial oxygen tension in critically ill patients with anaemia: The INsufficient Oxygenation in the Intensive Care Unit (INOX ICU-2) study BMJ open 2020;10 (5) [PubMed]
• Juffermans Nicole P., van den Brom Charissa E., Kleinveld Derek J. B. Targeting Endothelial Dysfunction in Acute Critical Illness to Reduce Organ Failure Anesthesia and analgesia 2020:1708-1720 [PubMed]
• van Manen Lisa, Maas Adrie, Roelofs Joris J. T. H., Vlaar Alexander P. J., van Bruggen Robin, Juffermans Nicole P. The Effect of Washing of Stored Red Blood Cell Transfusion Units on Post Transfusion Recovery and Outcome in a Pneumosepsis Animal Model Shock (Augusta, Ga.) 2020;54 (6):794-801 [PubMed]
• de Beer Friso M, Wieske Luuk, van Mierlo Gerard, Wouters Diana, Zeerleder Sacha, Bos Lieuwe D, Juffermans Nicole P, Schultz Marcus J, van der Poll Tom, Lagrand Wim K, Horn Janneke The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients Intensive Care Medicine Experimental 2020;8 (Suppl 1):74 [PubMed]
• Wirtz Mathijs R., Schalkers Daisy V., Goslings J. Carel, Juffermans Nicole P. The impact of blood product ratio and procoagulant therapy on the development of thromboembolic events in severely injured hemorrhaging trauma patients Transfusion 2020;60 (8):1873-1882 [PubMed]
• Juffermans Nicole P., Rademacher Peter, Laffey John G. The importance of discovery science in the development of therapies for the critically ill. Intensive Care Medicine Experimental 2020;8 (1)
• van Meenen David M P, Serpa Neto Ary, Paulus Frederique, Merkies Coen, Schouten Laura R, Bos Lieuwe D, Horn Janneke, Juffermans Nicole P, Cremer Olaf L, van der Poll Tom, Schultz Marcus J The predictive validity for mortality of the driving pressure and the mechanical power of ventilation Intensive Care Medicine Experimental 2020;8 (Suppl 1):60 [PubMed]
• Kleinveld Derek J. B., Sloos Pieter H., Noorman Femke, Maas M. Adrie W., Kers Jesper, Rijnhout Tim W. H., Zoodsma Margreet, Hoencamp Rigo, Hollmann Markus W., Juffermans Nicole P. The use of cryopreserved platelets in a trauma-induced hemorrhage model Transfusion 2020;60 (9):2079-2089 [PubMed]
• Juffermans Nicole P., Aubron C. cile, Duranteau Jacques, Vlaar Alexander P. J., Kor Daryl J., Muszynski Jennifer A., Spinella Philip C., Vincent Jean-Louis Transfusion in the mechanically ventilated patient Intensive care medicine 2020;46 (12):2450-2457 [PubMed]
• Vlaar Alexander P., Oczkowski Simon, de Bruin Sanne, Wijnberge Marije, Antonelli Massimo, Aubron Cecile, Aries Philippe, Duranteau Jacques, Juffermans Nicole P., Meier Jens, Murphy Gavin J., Abbasciano Riccardo, Muller Marcella, Shah Akshay, Perner Anders, Rygaard Sofie, Walsh Timothy S., Guyatt Gordon, Dionne J. C., Cecconi Maurizio Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine Intensive care medicine 2020;46 (4):673-696 [PubMed]
• Oczkowski Simon, Shah Akshay, Aubron C. cile, Wijnberge Marije, Vlaar Alexander P. J., de Bruin Sanne, Antonelli Massimo, Aries Philippe, Duranteau Jacques, Juffermans Nicole P., Meier Jens, Murphy Gavin J., Abbasciano Riccardo, Muller Marcella, Perner Anders, Rygaard Sofie, Walsh Timothy S., Dionne Joanna C., Guyatt Gordon, Cecconi Maurizio Treating critically ill anemic patients with erythropoietin: less is more Intensive care medicine 2020 [PubMed]
• Botta Michela, Tsonas Anissa M., Pillay Janesh, Boers Leonoor S., Algera Anna Geke, Bos Lieuwe D. J., Dongelmans Dave A., Hollmann Marcus W., Horn Janneke, Vlaar Alexander P. J., Schultz Marcus J., Neto Ary Serpa, Paulus Frederique, van Akkeren Jesse P., Algoe Cheetel K., van Amstel Rombout B., Baur Onno L., van de Berg Pablo, van den Berg Alida E., Bergmans Dennis C. J. J., van den Bersselaar Dido I., Bertens Freke A., Bindels Alexander J. G. H., de Boer Milou M., den Boer Sylvia, Boers Leonoor S., Bogerd Margriet, Bos Lieuwe D. J., Breel Jennifer S., de Bruin Hendrik, de Bruin Sanne, Bruna Caro L., Buiteman-Kruizinga Laura A., Cremer Olaf L., Determann Rogier M., Dieperink Willem, Dongelmans Dave A., Franke Hildegard S., Galek-Aldridge Michal S., de Graaff Mart J., Hagens Laura A., Haringman Jasper J., van der Heide Sebastiaan T., van der Heiden Pim L. J., Heijnen Nanon F. L., Hiel Stephan J. P., Hoeijmakers Lotte L., Hol Liselotte, Hollmann Markus W., Hoogendoorn Marga E., van der Horst Robrecht, Ie Evy L. K., Ivanov Dimitri P., Juffermans Nicole, Kho Eline, Koopman-van Gemert Ankie W. M. M., Koopmans Matty, Kucukcelebi Songul, Kuiper Michael A., de Lange Dylan W., van Mourik Niels, Nijbroek Sunny G. L. H., Onrust Marisa, Oostdijk Evelien A. N., Pennartz Charlotte J., Pisani Luigi, Purmer Ilse M., Rettig Thijs C. D., Roozeman Jan-Paul, Schuijt Michiel T. U., Schultz Marcus J., Serpa Neto Ary, Sleeswijk Mengalvio E., Smit Marry R., Spronk Peter E., Stilma Willemke, Strang Aart C., Tsonas Anissa M., Tuinman Pieter R., Valk Christel M. A., Veen-Schra Felicia L., Veldhuis Lars I., van Velzen Patricia, van der Ven Ward H., Vlaar Alexander P. J., van Vliet Peter, van der Voort Peter H. J., van Welie Louis, Wesselink Henrico J. F. T., van der Wier-Lubbers Hermien H., van Wijk Bas, Winters Tineke, Wong Wing Yi, van Zanten Arthur R. H. Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study lancet. Respiratory medicine 2020 [PubMed]

2019

• Vlaar Alexander P. J., Toy Pearl, Fung Mark, Looney Mark R., Juffermans Nicole P., Bux Juergen, Bolton-Maggs Paula, Peters Anna L., Silliman Christopher C., Kor Daryl J., Kleinman Steve A consensus redefinition of transfusion-related acute lung injury Transfusion 2019;59 (7):2465-2476 [PubMed]
• Juschten Jenny, Ingelse Sarah Anne, Maas Martinus Adrianus Wilhelmus, Girbes Armand Roelof Johan, Juffermans Nicole Petra, Schultz Marcus Josephus, Tuinman Pieter Roel Antithrombin plus alpha-1 protease inhibitor does not affect coagulation and inflammation in two murine models of acute lung injury Intensive Care Medicine Experimental 2019;7 (Suppl 1):36 [PubMed]
• Vlaar Alexander P. J., Toy Pearl, Fung Mark, Looney Mark R., Juffermans Nicole P., Bux Juergen, Bolton-Maggs P., Peters Anna L., Silliman Christopher C., Kor Daryl J., Kleinman Steve An update of the transfusion-related acute lung injury (TRALI) definition Transfusion clinique et biologique 2019;26 (4):354-356 [PubMed]
• Alshalani Abdulrahman, Li Wenhui, Juffermans Nicole P., Seghatchian Jerard, Acker Jason P. Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Transfusion and apheresis science : official journal of the World Apheresis Association 2019;58 (3):351-356 [PubMed]
• van Manen Lisa, Peters Anna L., van der Sluijs P. Matthijs, Nieuwland Rienk, van Bruggen Robin, Juffermans Nicole P. Clearance and phenotype of extracellular vesicles after red blood cell transfusion in a human endotoxemia model Transfusion and apheresis science : official journal of the World Apheresis Association 2019;58 (4):508-511 [PubMed]
• Rocha Leonardo L., Neto Ary S., Pessoa Camila M. S., Almeida M. rcio D., Juffermans Nicole P., Crochemore Tomaz, Rodrigues Roseny R., Filho Roberto R., Chaves Renato C. F., Cavalheiro Ana M., Prado Rogério R., Assunção Murillo S. C., Guardia Bianca D., Silva Eliézer, Corrêa Thiago D. Comparison of three transfusion protocols prior to central venous catheterization in patients with cirrhosis: A randomized controlled trial Journal of thrombosis and haemostasis 2019 [PubMed]
• Baksaas-Aasen Kjersti, van Dieren Susan, Balvers Kirsten, Juffermans Nicole P., Næss P. l A., Rourke Claire, Eaglestone Simon, Ostrowski Sisse R., Stensballe Jakob, Stanworth Simon, Maegele Marc, Goslings J. C., Johansson P. r I., Brohi Karim, Gaarder Christine Data-driven Development of ROTEM and TEG Algorithms for the Management of Trauma Hemorrhage: A Prospective Observational Multicenter Study Annals of surgery 2019;270 (6):1178-1185 [PubMed]
• Boshuizen Margit, van Bruggen Robin, Zaat Sebastian A, Schultz Marcus J, Aguilera Eli, Motos Ana, Senussi Tarek, Idone Francesco Antonio, Pelosi Paolo, Torres Antonio, Bassi Gianluigi Li, Juffermans Nicole P Development of a model for anemia of inflammation that is relevant to critical care Intensive Care Medicine Experimental 2019;7 (Suppl 1):47 [PubMed]
• Peters A. L., van de Weerdt E. K., Prinsze F., de Korte D., Juffermans N. P., Vlaar A. P. J. Donor characteristics do not influence transfusion-related acute lung injury incidence in a secondary analysis of two case-control studies Transfusion clinique et biologique 2019;26 (1):10-17 [PubMed]
• Kleinveld Derek J. B., Tuip-de Boer Anita M., Hollmann Markus W., Juffermans Nicole P. Early increase in anti-inflammatory biomarkers is associated with the development of multiple organ dysfunction syndrome in severely injured trauma patients Trauma Surgery and Acute Care Open 2019;4 (1) [PubMed]
• Ingelse Sarah A., Juschten Jenny, Maas Martinus A. W., Matute-Bello Gustavo, Juffermans Nicole P., van Woensel Job B. M., Bem Reinout A. Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats PLoS ONE 2019;14 (1) [PubMed]
• van de Groep Kirsten, Bos Martine P., Varkila Meri R. J., Savelkoul Paul H. M., Ong David S. Y., Derde Lennie P. G., Juffermans Nicole P., van der Poll Tom, Bonten Marc J. M., Cremer Olaf L., Schultz Marcus Moderate positive predictive value of a multiplex real-time PCR on whole blood for pathogen detection in critically ill patients with sepsis European journal of clinical microbiology & infectious diseases 2019;38 (10):1829-1836 [PubMed]
• Boshuizen Margit Modulating iron metabolism in anemia of inflammation in the critically ill 2019. 191p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Juffermans N. P. , Schultz M. J.; Co-supervisor: van Bruggen R.)
• van Paassen Judith, van Dissel Jaap T., Hiemstra Pieter S., Zwaginga Jaap Jan, Cobbaert Christa M., Juffermans Nicole P., de Wilde Rob B., Stijnen Theo, de Jonge Evert, Klautz Robert J., Sesmu Arbous M. Perioperative proADM-change is associated with the development of acute respiratory distress syndrome in critically ill cardiac surgery patients: A prospective cohort study Biomarkers in medicine 2019;13 (13):1081-1091 [PubMed]
• Weiss Bjoern, Weiss B., Prisco L., Boulanger C., Einav S., Gruber P., Laake J. H., Mehta S., Ostermann M., Antonelli M., Ben Nun M., Bollen Pinto B., Borkowska M., Borthwick M., Cecconi M., Costa-Pinto R., Derde L. P. G., Forni L. G., Galazzi A., Girbes A., Herridge M., Hofsø K., Juffermans N. P., Kesecioglu J., Lobo-Valbuena B., Machado F. R., Mekontso Dessap A., Metaxa V., Myatra S. N., Olusanya O., Rosenthal M., Rygård S. L., Schaller S. J., Underman K., Wade D. M. Statement paper on diversity for the European Society of Intensive Care Medicine (ESICM) Intensive care medicine 2019;45 (7):1002-1005 [PubMed]
• Scarlatescu Ecaterina, Juffermans Nicole P., Thachil Jecko The current status of viscoelastic testing in septic coagulopathy Thrombosis research 2019;183:146-152 [PubMed]
• Boshuizen Margit, van Hezel Maike E, van Manen Lisa, Straat Marleen, Somsen Yvemarie B O, Spoelstra-de Man Angelique M E, Blumberg Neil, van Bruggen Robin, Juffermans Nicole P The effect of red blood cell transfusion on iron metabolism in critically ill patients Transfusion 2019;59 (4):1196-1201 [PubMed]
• van Hezel Maike E., van Manen Lisa, Boshuizen Margit, Straat Marleen, de Cuyper Iris M., Beuger Boukje, Nieuwland Rienk, Tanck Michael W. T., de Korte Dirk, Zwaginga Jaap Jan, van Bruggen Robin, Juffermans Nicole P. The effect of red blood cell transfusion on platelet function in critically ill patients Thrombosis research 2019;184:115-121 [PubMed]
• Gall Lewis S., Vulliamy Paul, Gillespie Scarlett, Jones Timothy F., Pierre Rochelle S. J., Breukers Sabine E., Gaarder Christine, Juffermans Nicole P., Maegele Marc, Stensballe Jakob, Johansson P. r I., Davenport Ross A., Brohi Karim The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients Annals of surgery 2019;269 (6):1184-1191 [PubMed]
• Müller Marcella C. A., Meijers Joost C., van Meenen David M., Thachil Jecko, Juffermans Nicole P. Thromboelastometry in critically ill patients with disseminated intravascular coagulation Blood coagulation & fibrinolysis 2019;30 (5):181-187 [PubMed]
• Juffermans N. P., Wirtz M. R., Balvers K., Baksaas-Aasen K., van Dieren S., Gaarder C., Naess P. A., Stanworth S., Johansson P. I., Stensballe J., Maegele M., Goslings J. C., Brohi K. Towards patient-specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry Journal of thrombosis and haemostasis 2019;17 (3):441-448 [PubMed]
• de Bruin Sanne, Scheeren Thomas W. L., Bakker Jan, van Bruggen Robin, Vlaar Alexander P. J., Antonelli Massimo, Aubron Cecile, Cecconi Maurizio, Dionne Joanna C., Duranteau Jacques, Juffermans Nicole P., de Korte Dirk, Meier Jens, Murphy Gavin, Oczkowski Simon, Perner Anders, Walsh Timothy Transfusion practice in the non-bleeding critically ill: an international online survey-the TRACE survey Critical care (London, England) 2019;23 (1):309 [PubMed]
• Kleinveld Derek J B, Wirtz Mathijs R, van den Brink Daan P, Maas M Adrie W, Roelofs Joris J T H, Goslings J Carel, Hollmann Markus W, Juffermans Nicole P Use of a high platelet-to-RBC ratio of 2:1 is more effective in correcting trauma-induced coagulopathy than a ratio of 1:1 in a rat multiple trauma transfusion model Intensive Care Medicine Experimental 2019;7 (Suppl 1):42 [PubMed]
• Klanderman Robert B., Bosboom Joachim J., Maas Adrie A. W., Roelofs Joris J. T. H., de Korte Dirk, van Bruggen Robin, van Buul Jaap D., Zuurbier Coert J., Veelo Denise P., Hollmann Markus W., Vroom Margreeth B., Juffermans Nicole P., Geerts Bart F., Vlaar Alexander P. J. Volume incompliance and transfusion are essential for transfusion-associated circulatory overload: a novel animal model Transfusion 2019;59 (12):3617-3627 [PubMed]
• Wirtz Mathijs R., Jurgens Jordy, Zuurbier Coert J., Roelofs Joris J. T. H., Spinella Philip C., Muszynski Jennifer A., Carel Goslings J., Juffermans Nicole P. Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion Transfusion 2019;59 (1):134-145 [PubMed]
• Juffermans Nicole P, Schultz Marcus, Bos Lieuwe D, Penuelas Oscar, Laffey John, Lorente Jose A Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III) Intensive Care Medicine Experimental 2019;7 (Suppl 1):40 [PubMed]

2018

• Zamper Raffael P. C., Amorim Thiago C., Queiroz Veronica N. F., Lira Jordana D. O., Costa Luiz Guilherme V., Takaoka Flavio, Juffermans Nicole P., Neto Ary S. Association between viscoelastic tests-guided therapy with synthetic factor concentrates and allogenic blood transfusion in liver transplantation: A before-after study BMC anesthesiology 2018;18 (1) [PubMed]
• van Bree S. H. W., Prins M. M. C., Juffermans N. P. Auscultation for bowel sounds in patients with ileus: An outdated practice in the ICU? Netherlands journal of critical care 2018;26 (4):142-146
• Almizraq Ruqayyah J, Norris Philip J, Inglis Heather, Menocha Somaang, Wirtz Mathijs R, Juffermans Nicole, Pandey Suchitra, Spinella Philip C., Acker Jason P, Muszynski Jennifer A. Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity Blood advances 2018;2 (18):2296-2306 [PubMed]
• Ebner Florian, Harmon Matt B. A., Aneman Anders, Cronberg Tobias, Friberg Hans, Hassager Christian, Juffermans Nicole, Kjærgaard Jesper, Kuiper Michael, Mattsson Niklas, Pelosi Paolo, Ullén Susann, Undén Johan, Wise Matt P., Nielsen Niklas Carbon dioxide dynamics in relation to neurological outcome in resuscitated out-of-hospital cardiac arrest patients: An exploratory Target Temperature Management Trial substudy Critical care (London, England) 2018;22 (1) [PubMed]
• de Jonge E., de Wilde R. B. P., Juffermans N. P., Oostdijk E. A. N., Bernards A. T., van Essen E. H. R., Kuijper E. J., Visser C. E., Kesecioglu J., Bonten M. J. M. Carriage of antibiotic-resistant Gram-negative bacteria after discontinuation of selective decontamination of the digestive tract (SDD) or selective oropharyngeal decontamination (SOD) Critical care (London, England) 2018;22 (1) [PubMed]
• van de Groep Kirsten, Bos Martine P., Savelkoul Paul H. M., Rubenjan Anna, Gazenbeek Christel, Melchers Willem J. G., van der Poll Tom, Juffermans Nicole P., Ong David S. Y., Bonten Marc J. M., Cremer Olaf L. Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis European journal of clinical microbiology & infectious diseases 2018;37 (7):1333-1344 [PubMed]
• Simonis Fabienne D., Serpa Neto Ary, Binnekade Jan M., Braber Annemarije, Bruin Karina C. M., Determann Rogier M., Goekoop Geert-Jan, Heidt Jeroen, Horn Janneke, Innemee Gerard, de Jonge Evert, Juffermans Nicole P., Spronk Peter E., Steuten Lotte M., Tuinman Pieter Roel, de Wilde Rob B. P., Vriends Marijn, Gama de Abreu Marcelo, Pelosi Paolo, Schultz Marcus J. Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial JAMA 2018;320 (18):1872-1880 [PubMed]
• van Meenen David M. P., van der Hoeven Sophia M., Binnekade Jan M., de Borgie Corianne A. J. M., Merkus Maruschka P., Bosch Frank H., Endeman Henrik, Haringman Jasper J., van der Meer Nardo J. M., Moeniralam Hazra S., Slabbekoorn Mathilde, Muller Marcella C. A., Stilma Willemke, van Silfhout Bart, Serpa Neto Ary, ter Haar Hans F. M., van Vliet Jan, Wijnhoven Jan Willem, Horn Janneke, Juffermans Nicole P., Pelosi Paolo, Gama de Abreu Marcelo, Schultz Marcus J., Paulus Frederique Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial JAMA 2018;319 (10):993-1001 [PubMed]
• Soussi Sabri, Berger Mette M., Colpaert Kirsten, Dünser Martin W., Guttormsen Anne Berit, Juffermans Nicole P., Knape Paul, Koksal Guniz, Lavrentieva Athina, Leclerc Thomas, Lorente José A., Martin-Loeches Ignacio, Metnitz Philipp, Pantet Olivier, Pelosi Paolo, Rousseau Anne-Françoise, Sjöberg Folke, Legrand Matthieu Hemodynamic management of critically ill burn patients: An international survey Critical care (London, England) 2018;22 (1) [PubMed]
• Itenov Theis Skovsgaard, Johansen Maria Egede, Bestle Morten, Thormar Katrin, Hein Lars, Gyldensted Louise, Lindhardt Anne, Christensen Henrik, Estrup Stine, Pedersen Henrik Planck, Harmon Matthew, Soni Uday Kant, Perez-Protto Silvia, Wesche Nicolai, Skram Ulrik, Petersen John Asger, Mohr Thomas, Waldau Tina, Poulsen Lone Musaeus, Strange Ditte, Juffermans Nicole P., Sessler Daniel I., Tønnesen Else, Møller Kirsten, Kristensen Dennis Karsten, Cozzi-Lepri Alessandro, Lundgren Jens D., Jensen Jens-Ulrik, Jensen Jens-Ulrik Stæhr, Lundgren Jens, Planck Pedersen Henrik, Illkjær Susanne, Masur Henry, Torp-Pedersen Christian, Copas Andrew, Nielsen Birgit Riis, Grarup Jesper, Hansen Jette, Nielsen Kim, Valbjørn Lone, Lauritzen Sanne, Kold Tina, Grundahl Kathrine, Rasmussen Rikke Hein, Wesche Nikolaj, Blom Hasse, Jensen Peer Eske, Galle Tina, Thaarslund Bente, Skandov Camilla Induced hypothermia in patients with septic shock and respiratory failure (CASS): a randomised, controlled, open-label trial lancet. Respiratory medicine 2018;6 (3):183-192 [PubMed]
• Aslami Hamid, Beurskens Charlotte J. P., Tuip Anita M., Horn Janneke, Juffermans Nicole P. Induced hypothermia is associated with reduced circulating subunits of mitochondrial DNA in cardiac arrest patients Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis 2018;29 (4):525-528 [PubMed]
• Serpa Neto Ary, Juffermans Nicole P., Hemmes Sabrine N. T., Barbas Carmen S. V., Beiderlinden Martin, Biehl Michelle, Fernandez-Bustamante Ana, Futier Emmanuel, Gajic Ognjen, Jaber Samir, Kozian Alf, Licker Marc, Lin Wen-Qian, Memtsoudis Stavros G., Miranda Dinis Reis, Moine Pierre, Paparella Domenico, Ranieri Marco, Scavonetto Federica, Schilling Thomas, Selmo Gabriele, Severgnini Paolo, Sprung Juraj, Sundar Sugantha, Talmor Daniel, Treschan Tanja, Unzueta Carmen, Weingarten Toby N., Wolthuis Esther K., Wrigge Hermann, Gama de Abreu Marcelo, Pelosi Paolo, Schultz Marcus J. Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis Annals of translational medicine 2018;6 (2):23 [PubMed]
• Schauwvlieghe Alexander F. A. D., Rijnders Bart J. A., Philips Nele, Verwijs Rosanne, Vanderbeke Lore, van Tienen Carla, Lagrou Katrien, Verweij Paul E., van de Veerdonk Frank L., Gommers Diederik, Spronk Peter, Bergmans Dennis C. J. J., Hoedemaekers Astrid, Andrinopoulou Eleni-Rosalina, van den Berg Charlotte H. S. B., Juffermans Nicole P., Hodiamont Casper J., Vonk Alieke G., Depuydt Pieter, Boelens Jerina, Wauters Joost Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study lancet. Respiratory medicine 2018;6 (10):782-792 [PubMed]
• Boshuizen Margit, Binnekade Jan M., Nota Benjamin, van de Groep Kirsten, Cremer Olaf L., Tuinman Pieter R., Horn Janneke, Schultz Marcus J., van Bruggen Robin, Juffermans Nicole P., de Beer Friso M., Bos Lieuwe D. J., Glas Gerie J., van Hooijdonk Roosmarijn T. M., Schouten Laura R. A., Straat Marleen, Witteveen Esther, Wieske Luuk, Hoogendijk Arie J., Huson Mischa A., Scicluna Brendon P., van der Poll Tom, van Vught Lonneke A., Wiewel Maryse A., Bonten Marc J. M., Frencken Jos F., Klein Klouwenberg Peter M. C., Koster-Brouwer Maria E., Ong David S. Y., Verboom Diana M. Iron metabolism in critically ill patients developing anemia of inflammation: a case control study Annals of intensive care 2018;8 (1) [PubMed]
• Remy Kenneth E., Hall Mark W., Cholette Jill, Juffermans Nicole P., Nicol Kathleen, Doctor Allan, Blumberg Neil, Spinella Philip C., Norris Philip J., Dahmer Mary K., Muszynski Jennifer A. Mechanisms of red blood cell transfusion-related immunomodulation Transfusion 2018;58 (3):804-815 [PubMed]
• Jansen Marcel P. B., Pulskens Wilco P., Butter Loes M., Florquin Sandrine, Juffermans Nicole P., Roelofs Joris J. T. H., Leemans Jaklien C. Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction Shock (Augusta, Ga.) 2018;49 (3):301-310 [PubMed]
• Walsh Timothy S., Juffermans Nicole P. New blood for old? High quality evidence that fresh red blood cells confer no benefit for critically ill patients Intensive care medicine 2018;44 (4):506-508 [PubMed]
• Witteveen Esther, Wieske Luuk, de Beer Friso M, Juffermans Nicole P, Verhamme Camiel, Schultz Marcus J, van Schaik Ivo N, Horn Janneke No association between systemic complement activation and intensive care unit-acquired weakness Annals of translational medicine 2018;6 (7):115 [PubMed]
• Juffermans Nicole P. Outcome of red blood cell transfusion: Ladies first, but perhaps not in donation Journal of thoracic disease 2018;10 (2):641-643 [PubMed]
• Harmon Matthew B. A., van Meenen David. M. P., van der Veen Annelou L. I. P., Binnekade Jan M., Dankiewicz Josef, Ebner Florian, Nielsen Niklas, Pelosi Paolo, Schultz Marcus J., Horn Janneke, Friberg Hans, Juffermans Nicole P. Practice of mechanical ventilation in cardiac arrest patients and effects of targeted temperature management: A substudy of the targeted temperature management trial Resuscitation 2018;129:29-36 [PubMed]
• Bukkems Laura H., Roger Claire, Hodiamont Caspar J., Lefrant Jean-Yves, Juffermans Nicole P., Roberts Jason A., van Hest Reinier M. Predictive performance of a gentamicin population pharmacokinetic model in two western populations of critically ill patients International journal of antimicrobial agents 2018;52 (2):218-225 [PubMed]
• Algera Anna Geke, Pisani Luigi, Bergmans Dennis C. J., den Boer Sylvia, de Borgie Corianne A. J., Bosch Frank H., Bruin Karina, Cherpanath Thomas G., Determann Rogier M., Dondorp Arjen M., Dongelmans Dave A., Endeman Henrik, Haringman Jasper J., Horn Janneke, Juffermans Nicole P., van Meenen David M., van der Meer Nardo J., Merkus Maruschka P., Moeniralam Hazra S., Purmer Ilse, Tuinman Pieter Roel, Slabbekoorn Mathilde, Spronk Peter E., Vlaar Alexander P. J., Gama de Abreu Marcelo, Pelosi Paolo, Serpa Neto Ary, Schultz Marcus J., Paulus Frederique RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: Protocol for a randomized controlled trial Trials 2018;19 (1) [PubMed]
• Peters Anna L., van de Weerdt Emma K., Goudswaard Eline J., Binnekade Jan M., Zwaginga Jaap J., Beckers Erik A. M., Zeerleder Sacha S., van Kraaij Marian G. J., Juffermans Nicole P., Vlaar Alexander P. J. Reporting transfusion-related acute lung injury by clinical and preclinical disciplines Blood transfusion 2018;16 (3):227-234 [PubMed]
• Heunks L., Juffermans N. P., Pickkers P., Slooter A. J. C. Research collaboration critical care in the Netherlands: RCCCNet Netherlands journal of critical care 2018;26 (4):161-162
• van Someren Gréve Frank, Juffermans Nicole P., Bos Lieuwe D. J., Binnekade Jan M., Braber Annemarije, Cremer Olaf L., de Jonge Evert, Molenkamp Richard, Ong David S. Y., Rebers Sjoerd P. H., Spoelstra-de Man Angelique M. E., van der Sluijs Koenraad F., Spronk Peter E., Verheul Kirsten D., de Waard Monique C., de Wilde Rob B. P., Winters Tineke, de Jong Menno D., Schultz Marcus J. Respiratory Viruses in Invasively Ventilated Critically Ill Patients-A Prospective Multicenter Observational Study Critical care medicine 2018;46 (1):29-36 [PubMed]
• Peters Anna L., Vlaar Alexander P. J., van Bruggen Robin, de Korte Dirk, Meijers Joost C. M., Nieuwland Rienk, Juffermans Nicole P. Transfusion of autologous extracellular vesicles from stored red blood cells does not affect coagulation in a model of human endotoxemia Transfusion 2018;58 (6):1486-1493 [PubMed]
• van Someren Gréve Frank, van der Sluijs Koenraad F., Tuip Anita M., Schultz Marcus J., de Jong Menno D., Juffermans Nicole P. Treatment with broadly neutralizing influenza antibodies reduces severity of secondary pneumococcal pneumonia in mice Journal of medical virology 2018;90 (9):1431-1437 [PubMed]

2017

• Nederlof Rianne, Weber Nina C., Juffermans Nicole P., de Mol Bas A. M. J., Hollmann Markus W., Preckel Benedikt, Zuurbier Coert J. A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients BMC anesthesiology 2017;17 (1) [PubMed]
• Peters Anna-Linda Blood transfusion: Transfusion-related acute lung injury: back to basics 2017. 282p. ISBN 9789402805390. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Juffermans N. P.; Co-supervisor: Vlaar A. P. J.)
• Balvers K., van Dieren S., Baksaas-Aasen K., Gaarder C., Brohi K., Eaglestone S., Stanworth S., Johansson P. I., Ostrowski S. R., Stensballe J., Maegele M., Goslings J. C., Juffermans N. P., Bergman R., Naess P. A., Kolstadbråten K. M., Rourke C., Gall L., Curry N., Stürmer E. K., Schäfer N., Driessen A., Orr A., Schubert A., Görlinger K., Harrison M., Buchanan J., Char A., Neble S., Sayel H. Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy British journal of surgery 2017;104 (3):222-229 [PubMed]
• Hodiamont Caspar J., Juffermans Nicole P., Bouman Catherine S. C., de Jong Menno D., Mathôt Ron A. A., van Hest Reinier M. Determinants of gentamicin concentrations in critically ill patients: a population pharmacokinetic analysis International journal of antimicrobial agents 2017;49 (2):204-211 [PubMed]
• Straat Marleen, Tuip Anita, Klei Thomas R. L., Beuger Boukje M., Roelofs Joris J. T. H., van Bruggen Robin, Juffermans Nicole P. ENDOTOXEMIA RESULTS IN TRAPPING OF TRANSFUSED RED BLOOD CELLS IN LUNGS WITH ASSOCIATED LUNG INJURY Shock (Augusta, Ga.) 2017;48 (4):484-489 [PubMed]
• Helmerhorst Hendrik J. F., Schouten Laura R. A., Wagenaar Gerry T. M., Juffermans Nicole P., Roelofs Joris J. T. H., Schultz Marcus J., de Jonge Evert, van Westerloo David J. Hyperoxia provokes a time- and dose-dependent inflammatory response in mechanically ventilated mice, irrespective of tidal volumes Intensive Care Medicine Experimental 2017;5 (1) [PubMed]
• Bos L. D., Schouten L. R., van Vught L. A., Wiewel M. A., Ong D. S. Y., Cremer O., Artigas A., Martin-Loeches I., Hoogendijk A. J., van der Poll T., Horn J., Juffermans N., Calfee C. S., Schultz M. J., Frencken Jos F., Bonten Marc, Klein Klouwenberg Peter M. C., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Straat Marleen, Witteveen Esther, Glas Gerie J., Wieske Luuk, Scicluna Brendon P., Belkasim-Bohoudi H. Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis Thorax 2017;72 (10):876-883 [PubMed]
• Dankiewicz Josef, Nielsen Niklas, Linder Adam, Kuiper Michael, Wise Matthew P., Cronberg Tobias, Erlinge David, Gasche Yvan, Harmon Matthew B., Hassager Christian, Horn Janneke, Kjaergaard Jesper, Pellis Tommaso, Stammet Pascal, Undén Johan, Wanscher Michael, Wetterslev Jørn, Åneman Anders, Ullén Susann, Juffermans Nicole P., Friberg Hans Infectious complications after out-of-hospital cardiac arrest-A comparison between two target temperatures Resuscitation 2017;113:70-76 [PubMed]
• Boshuizen Margit, Binnekade Johannes M., Nota Benjamin, Juffermans Nicole P. Iron Metabolism in Critically Ill Patients Developing Anemia of Inflammation. Transfusion 2017;57 (3):53A-53A
• Baksaas-Aasen Kjersti, Gall Lewis, Eaglestone Simon, Rourke Claire, Juffermans Nicole P., Goslings J. Carel, Naess Paal Aksel, van Dieren Susan, Ostrowski Sisse Rye, Stensballe Jakob, Maegele Marc, Stanworth Simon J., Gaarder Christine, Brohi Karim, Johansson Per I. iTACTIC - implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial Trials 2017;18 (1):486 [PubMed]
• Juschten Jenny, Tuinman Pieter R., Juffermans Nicole P., Dixon Barry, Levi Marcel, Schultz Marcus J. Nebulized anticoagulants in lung injury in critically ill patients-an updated systematic review of preclinical and clinical studies Annals of translational medicine 2017;5 (22):444 [PubMed]
• Juffermans Nicole P., Vlaar Alexander P. Possible TRALI is a real entity Transfusion 2017;57 (10):2539-2541 [PubMed]
• Müller Marcella C. A., Stanworth Simon J., Coppens Michiel, Juffermans Nicole P. Recognition and Management of Hemostatic Disorders in Critically Ill Patients Needing to Undergo an Invasive Procedure Transfusion medicine reviews 2017;31 (4):223-229 [PubMed]
• Bos Lieuwe D., Stips Cheryl, Schouten Laura R., van Vught Lonneke A., Wiewel Maryse A., Wieske Luuk, van Hooijdonk Roosmarijn T., Straat Marleen, de Beer Friso M., Glas Gerie J., Visser Caroline E., de Jonge Evert, Juffermans Nicole P., Horn Janneke, Schultz Marcus J. Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination Intensive care medicine 2017;43 (10):1535-1537 [PubMed]
• Ong David S. Y., Frencken Jos F., Klein Klouwenberg Peter M. C., Juffermans Nicole, van der Poll Tom, Bonten Marc J. M., Cremer Olaf L. Short-Course Adjunctive Gentamicin as Empirical Therapy in Patients With Severe Sepsis and Septic Shock: A Prospective Observational Cohort Study Clinical infectious diseases 2017;64 (12):1731-1736 [PubMed]
• Harmon Matthew B. A., Wiewel Maryse A., Wiersinga W. Joost, Juffermans Nicole P. Should we assume that hypothermia is a dysfunction in sepsis? Authors' Response Critical care medicine 2017;21 [PubMed]
• van Hezel Maike E., Nieuwland Rienk, van Bruggen Robin, Juffermans Nicole P. The Ability of Extracellular Vesicles to Induce a Pro-Inflammatory Host Response International journal of molecular sciences 2017;18 (6):1285 [PubMed]
• Hodiamont C. J., Janssen J. M., de Jong M. D., Mathôt R. A., Juffermans N. P., van Hest R. M. Therapeutic Drug Monitoring of Gentamicin Peak Concentrations in Critically Ill Patients Therapeutic drug monitoring 2017;39 (5):522-530 [PubMed]
• Boshuizen M., van der Ploeg K., von Bonsdorff L., Biemond B. J., Zeerleder S. S., van Bruggen R., Juffermans N. P. Therapeutic use of transferrin to modulate anemia and conditions of iron toxicity Blood reviews 2017;31 (6):400-405 [PubMed]
• Asehnoune Karim, Balogh Zsolt, Citerio Giuseppe, Cap Andre, Billiar Timothy, Stocchetti Nino, Cohen Mitchell J., Pelosi Paolo, Curry Nicola, Gaarder Christine, Gruen Russell, Holcomb John, Hunt Beverley J., Juffermans Nicole P., Maegele Mark, Midwinter Mark, Moore Frederick A., O'Dwyer Michael, Pittet Jean-François, Schöchl Herbert, Schreiber Martin, Spinella Philip C., Stanworth Simon, Winfield Robert, Brohi Karim The research agenda for trauma critical care Intensive care medicine 2017;43 (9):1340-1351 [PubMed]
• Kor Daryl J., Juffermans Nicole P. Transfusion in Critical Care Transfusion medicine reviews 2017;31 (4):203-204 [PubMed]
• Peters Anna L., van Hezel Maike E., Klanderman Robert B., Tuip-de Boer Anita M., Wiersinga W. Joost, van der Spek Anne H., van Bruggen Robin, de Korte Dirk, Juffermans Nicole P., Vlaar Alexander P. J. Transfusion of 35-day-stored red blood cells does not alter lipopolysaccharide tolerance during human endotoxemia Transfusion 2017;57 (6):1359-1368 [PubMed]
• Peters Anna L., Kunanayagam Renoja K., van Bruggen Robin, de Korte Dirk, Juffermans Nicole P., Vlaar Alexander P. J. Transfusion of 35-day stored red blood cells does not result in increase of plasma non-transferrin bound iron in human endotoxemia Transfusion 2017;57 (1):53-59 [PubMed]
• Muszynski Jennifer A., Spinella Philip C., Cholette Jill M., Acker Jason P., Hall Mark W., Juffermans Nicole P., Kelly Daniel P., Blumberg Neil, Nicol Kathleen, Liedel Jennifer, Doctor Allan, Remy Kenneth E., Tucci Marisa, Lacroix Jacques, Norris Philip J. Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness Transfusion 2017;57 (1):195-206 [PubMed]
• Schopman J. E. , Bouman C. S., Canté C. M. , Kouwen S. , Holleman F. , Juffermans N. P. Use of two continuous venovenous haemofiltration devices in metformin-associated lactic acidosis Netherlands journal of critical care 2017;25 (1):15-17
• Wirtz Mathijs R., Baumann Holger M., Klinkspoor J. Henriëtte, Goslings J. Carel, Juffermans Nicole P. Viscoelastic Testing in Trauma Seminars in thrombosis and hemostasis 2017;43 (4):375-385 [PubMed]

2016

• Balvers Kirsten, Saleh Sarah, Zeerleder Sacha S., Klinkspoor J. Henriette, Goslings J. Carel, Juffermans Nicole P. Are there any alternatives for transfusion of AB plasma as universal donor in an emergency release setting? Transfusion 2016;56 (6):1469-1474 [PubMed]
• Peters Anna L., Beuger Boukje, Mock Donald M., Widness John A., de Korte Dirk, Juffermans Nicole P., Vlaar Alexander P. J., van Bruggen Robin Clearance of stored red blood cells is not increased compared with fresh red blood cells in a human endotoxemia model Transfusion 2016;56 (6):1362-1369 [PubMed]
• van Someren Gréve Frank, Ong David S. Y., Cremer Olaf L., Bonten Marc J. M., Bos Lieuwe D. J., de Jong Menno D., Schultz Marcus J., Juffermans Nicole P. Clinical practice of respiratory virus diagnostics in critically ill patients with a suspected pneumonia: A prospective observational study Journal of clinical virology 2016;83:37-42 [PubMed]
• Helmerhorst Hendrik J. F., Schultz Marcus J., van der Voort Peter H. J., Bosman Robert J., Juffermans Nicole P., de Wilde Rob B. P., van den Akker-van Marle M. Elske, van Bodegom-Vos Leti, de Vries Marieke, Eslami Saeid, de Keizer Nicolette F., Abu-Hanna Ameen, van Westerloo David J., de Jonge Evert Effectiveness and Clinical Outcomes of a Two-Step Implementation of Conservative Oxygenation Targets in Critically Ill Patients: A Before and After Trial Critical care medicine 2016;44 (3):554-563 [PubMed]
• Cherpanath Thomas G. V., Landburg Pearl P., Lagrand Wim K., Schultz Marcus J., Juffermans Nicole P. Effect of extracorporeal CO2 removal on right ventricular and hemodynamic parameters in a patient with acute respiratory distress syndrome Perfusion 2016;31 (6):525-529 [PubMed]
• Straat Marleen, Boing Anita N., Tuip-de Boer Anita, Nieuwland Rienk, Juffermans Nicole P. Extracellular Vesicles from Red Blood Cell Products Induce a Strong Pro-Inflammatory Host Response, Dependent on Both Numbers and Storage Duration Transfusion medicine and hemotherapy 2016;43 (4):302-305 [PubMed]
• Brevoord Daniel, Beurskens Charlotte J. P., van den Bergh Walter M., Lagrand Wim K., Juffermans Nicole P., Binnekade Jan M., Preckel Benedikt, Horn Janneke Helium ventilation for treatment of post-cardiac arrest syndrome: A safety and feasibility study Resuscitation 2016;107:145-149 [PubMed]
• Balvers Kirsten, van der Horst Marjolein, Graumans Maarten, Boer Christa, Binnekade Jan M., Goslings J. Carel, Juffermans Nicole P. Hypothermia as a predictor for mortality in trauma patients at admittance to the Intensive Care Unit Journal of emergencies, trauma, and shock 2016;9 (3):97-102 [PubMed]
• van Lieshout E. J., Juffermans N. P., Dongelmans D. A., de Haan R. J. Interhospital critical care transports: a safe trip indeed! Intensive care medicine 2016;42 (11):1837 [PubMed]
• Pham Huy P., Müller Marcella C., Williams Lance A., Juffermans Nicole P. Mathematical model and calculation to predict the effect of prophylactic plasma transfusion on change in international normalized ratio in critically ill patients with coagulopathy Transfusion 2016;56 (4):926-932 [PubMed]
• van Lieshout Erik-Jan Mobile intensive care unit 2016. 157p. ISBN 9789461699879. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Vroom M. B., de Haan R. J.; Co-supervisors: Juffermans N. P., Binnenkade J. M.)
• van Lieshout Erik Jan Mobile intensive care unit: Technical and clinical aspects of interhospital critical care transport 2016. 157p. ISBN 9789461699879. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Vroom M. B., de Haan R. J.; Co-supervisors: Juffermans N. P. , Binnekade J. M.)
• Straat Marleen, van Hezel Maike E., Böing Anita, Tuip-de Boer Anita, Weber Nina, Nieuwland Rienk, van Bruggen Robin, Juffermans Nicole P. Monocyte-mediated activation of endothelial cells occurs only after binding to extracellular vesicles from red blood cell products, a process mediated by β-integrin Transfusion 2016;56 (12):3012-3020 [PubMed]
• de Beer Friso, Lagrand Wim, Glas Gerie J., Beurskens Charlotte J. P., van Mierlo Gerard, Wouters Diana, Zeerleder Sacha, Roelofs Joris J. T. H., Juffermans Nicole P., Horn Janneke, Schultz Marcus J. Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia Cell biochemistry and biophysics 2016;74 (4):545-552 [PubMed]
• van Lieshout Erik Jan, Binnekade Jan, Reussien Elmer, Dongelmans Dave, Juffermans Nicole P., de Haan Rob J., Schultz Marcus J., Vroom Margreeth B. Nurses versus physician-led interhospital critical care transport: a randomized non-inferiority trial Intensive care medicine 2016;42 (7):1146-1154 [PubMed]
• Balvers Kirsten Optimising diagnosis and treatment of coagulopathy in severely injured trauma patients 2016. 237p. ISBN 9789402802023. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Goslings J. C.; Co-supervisor: Juffermans N. P.)
• Iba Toshiaki, Ito Takashi, Maruyama Ikuro, Jilma Bernd, Brenner Thorsten, Müller Marcella C. A., Juffermans Nicole P., Thachil Jecko Potential diagnostic markers for disseminated intravascular coagulation of sepsis Blood reviews 2016;30 (2):149-155 [PubMed]
• Muller M. A., Juffermans N. P. Risk estimation and management of coagulopathy in ICU patients in need of an invasive procedure. Netherlands journal of critical care 2016;24 (3):6-11
• Wiewel Maryse A., Harmon Matthew B., van Vught Lonneke A., Scicluna Brendon P., Hoogendijk Arie J., Horn Janneke, Zwinderman Aeilko H., Cremer Olaf L., Bonten Marc J., Schultz Marcus J., van der Poll Tom, Juffermans Nicole P., Wiersinga W. Joost Risk factors, host response and outcome of hypothermic sepsis Critical care (London, England) 2016;20 (1):328 [PubMed]
• Westhall Erik, Rossetti Andrea O., van Rootselaar Anne-Fleur, Wesenberg Kjaer Troels, Horn Janneke, Ullén Susann, Friberg Hans, Nielsen Niklas, Rosén Ingmar, Åneman Anders, Erlinge David, Gasche Yvan, Hassager Christian, Hovdenes Jan, Kjaergaard Jesper, Kuiper Michael, Pellis Tommaso, Stammet Pascal, Wanscher Michael, Wetterslev Jørn, Wise Matt P., Cronberg Tobias, Saxena Manoj, Miller Jennene, Inskip Deborah, Macken Lewis, Finfer Simon, Eatough Noel, Hammond Naomi, Bass Frances, Yarad Elizabeth, O'Connor Anne, Bird Simon, Jewell Timothy, Davies Gareth, Ng Karl, Coward Sharon, Stewart Antony, Micallef Sharon, Parker Sharyn, Cortado Dennis, Gould Ann, Harward Meg, Thompson Kelly, Glass Parisa, Myburgh John, Smid Ondrej, Belholavek Jan, Juffermans Nicole P., Boerma EC Standardized EEG interpretation accurately predicts prognosis after cardiac arrest Neurology 2016;86 (16):1482-1490 [PubMed]
• Peters Anna L., van Hezel Maike E., Cortjens Bart, Tuip-de Boer Anita M., van Bruggen Robin, de Korte Dirk, Jonkers René E., Bonta Peter I., Zeerleder Sacha S., Lutter Rene, Juffermans Nicole P., Vlaar Alexander P. J. Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans Critical care medicine 2016;44 (6):e412-e419 [PubMed]
• Engele Leo J., Straat Marleen, van Rooijen Ingeborg H. M., de Vooght Karen M. K., Cremer Olaf L., Schultz Marcus J., Bos Lieuwe D. J., Juffermans Nicole P., de Beer Friso M., van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., Wieske Luuk, van der Poll Tom, Bonten Marc J. M., Frencken Jos F., Klein Klouwenberg Peter M. C., Ong DavidS Y. Transfusion of platelets, but not of red blood cells, is independently associated with nosocomial infections in the critically ill Annals of intensive care 2016;6 (1):67 [PubMed]
• Straat Marleen Unexpected effects of transfusion in the critically ill 2016. 236p. ISBN 9789461698902. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Vroom M. B.; Co-supervisors: Juffermans N. P., van Bruggen R.)

2015

• Spitalnik Steven L., Triulzi Darrell, Devine Dana V., Dzik Walter H., Eder Anne F., Gernsheimer Terry, Josephson Cassandra D., Kor Daryl J., Luban Naomi L. C., Roubinian Nareg H., Mondoro Traci, Welniak Lisbeth A., Zou Shimian, Glynn Simone, Hendrickson Jeanne, Zimring James C., Yazdanbakhsh Karina, Delaney Megan, Ware Russell E., Tinmouth Alan, Doctor Allan, Migliaccio Anna Rita, Fergusson Dean A., Widness John A., Carson Jeffrey L., Hess John, Roback John D., Waters Jonathan H., Cancelas Jose A., Gladwin Mark T., Rogers Mary A. M., Ness Paul M., Rao Sunil, Watkins Timothy R., Spinella Philip C., Kaufman Richard M., Slichter Sherrill J., McCullough Jeffrey, Blumberg Neil, Webert Kathryn E., Fitzpatrick Michael, Shander Aryeh, Corash Laurence M., Murphy Michael, Silberstein Leslie E., Dumont Larry J., Mitchell W. Beau, Juffermans Nicole P., Vlaar Alexander P. J., de Kort Wim 2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium Transfusion 2015;55 (9):2282-2290 [PubMed]
• Straat M., Klei Trl, de Korte D., van Bruggen R., Juffermans N. P. Accelerated clearance of human red blood cells in a rat transfusion model Intensive Care Medicine Experimental 2015;3 (1):27 [PubMed]
• Schouten Laura R. A., Schultz Marcus J., van Kaam Anton H., Juffermans Nicole P., Bos Albert P., Wösten-van Asperen Roelie M. Association between Maturation and Aging and Pulmonary Responses in Animal Models of Lung Injury A Systematic Review Anesthesiology 2015;123 (2):389-408 [PubMed]
• van Hooijdonk Roosmarijn T. M., Binnekade Jan M., Bos Lieuwe D. J., Horn Janneke, Juffermans Nicole P., Abu-Hanna Ameen, Schultz Marcus J. Associations between bolus infusion of hydrocortisone, glycemic variability and insulin infusion rate variability in critically Ill patients under moderate glycemic control Annals of intensive care 2015;5 (1):34 [PubMed]
• van Hooijdonk Roosmarijn T. M., Binnekade Jan M., Abu-Hanna Ameen, van Braam Houckgeest Floris, Hofstra Lieuwe S., Horn Janneke, Kuiper Michael A., Juffermans Nicole P., van den Oever Huub L. A., van der Sluijs Johannes P., Spronk Peter E., Schultz Marcus J. Associations between dynamics of the blood glucose level after hypoglycemia and intensive care unit mortality: a retrospective multicenter study Intensive care medicine 2015;41 (10):1864-1865 [PubMed]
• van den Hurk G. H. A. M., Janssen J. M., Juffermans N. P., van Hest R. M. De kwaliteit van doseringsadviezen bij therapeutic drug monitoring van aminoglycosiden op de intensive care Pharmaceutisch Weekblad 2015;150:160-164
• Schäfer Nadine, Driessen Arne, Fröhlich Matthias, Stürmer Ewa K., Maegele Marc, Johansson Pär I., Ostrowski Sisse R., Stensballe Jakob, Goslings J. Carel, Juffermans Nicole, Balvers Kirsten, Neble Sylvie, van Dieren Susan, Gaarder Christine, Naess Pål A., Kolstadbraten Knut Magne, Brohi Karim, Eaglestone Simon, Rourke Claire, Campbell Helen, Curry Nicola, Stanworth Simon, Harrison Michael, Buchanan James, Soyel Hamit, Gall Lewis, Orr Adrian, Char Ahmed, Görlinger Klaus, Schubert Axel Diversity in clinical management and protocols for the treatment of major bleeding trauma patients across European level I Trauma Centres Scandinavian journal of trauma, resuscitation and emergency medicine 2015;23:74 [PubMed]
• Straat Marleen, Müller Marcella C. A., Meijers Joost C. M., Arbous Mendi S., Spoelstra-de Man Angelique M. E., Beurskens Charlotte J. P., Vroom Margreeth B., Juffermans Nicole P. Effect of transfusion of fresh frozen plasma on parameters of endothelial condition and inflammatory status in non-bleeding critically ill patients: a prospective substudy of a randomized trial Critical care (London, England) 2015;19 (1):163 [PubMed]
• Balvers Kirsten, Coppens Michiel, van Dieren Susan, van Rooyen-Schreurs Ingeborg H. M., Klinkspoor Henriëtte J., Zeerleder Sacha S., Baumann Holger M., Goslings J. Carel, Juffermans Nicole P. Effects of a hospital-wide introduction of a massive transfusion protocol on blood product ratio and blood product waste Journal of emergencies, trauma, and shock 2015;8 (4):199-204 [PubMed]
• Balvers Kirsten, Curry Nicola, Kleinveld Derek J. B., Böing Anita N., Nieuwland Rienk, Goslings J. Carel, Juffermans Nicole P. Endogenous microparticles drive the proinflammatory host immune response in severely injured trauma patients Shock (Augusta, Ga.) 2015;43 (4):317-321 [PubMed]
• Juffermans Nicole P., Boermeester Marja A. Ernstige acute pancreatitisin: A. C. J. M. de Pont, M. J. Schultz, F. Paulus, M. B. Vroom, editors. Protocollen voor de intensive care. Utrecht: De Tijdstroom; 2015. p. 193-198, ISBN 9789058982599
• Müller M. C. A., Straat M., Meijers J. C. M., Klinkspoor J. H., de Jonge E., Arbous M. S., Schultz M. J., Vroom M. B., Juffermans N. P. Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy Journal of thrombosis and haemostasis 2015;13 (6):989-997 [PubMed]
• Müller M. C. A., Juffermans N. P. Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy: reply Journal of thrombosis and haemostasis 2015;13 (10):1943-1944 [PubMed]
• Mulder Hilde D., Augustijn Quinten J. J., van Woensel Job B., Bos Albert P., Juffermans Nicole P., Wösten-van Asperen Roelie M. Incidence, risk factors, and outcome of transfusion-related acute lung injury in critically ill children: a retrospective study Journal of critical care 2015;30 (1):55-59 [PubMed]
• van Someren Gréve Frank, Schultz Marcus J., de Jong Menno D., Juffermans Nicole P. Influenza and Other Respiratory Viruses Are Underdiagnosed in Critically Ill Patients Critical care medicine 2015;43 (4):E117 [PubMed]
• Driessen A., Schäfer N., Albrecht V., Schenk M., Fröhlich M., Stürmer E. K., Maegele M., Johansson Pär, Ostrowski Sisse Rye, Tuovinen Hannele, Stensballe Jakob, Goslings Johann Carel, Juffermans Nicole, Balvers Kirsten, Gaarder Christine, Brohi Karim, Eaglestone Simon, Rourke Claire, Campbell Helen, Curry Nicola, Stanworth Simon, Maegele Marc, Stürmer Ewa K., Schäfer Nadine, Driessen Arne, Orr Adrian, Schubert Axel Infrastructure and clinical practice for the detection and management of trauma-associated haemorrhage and coagulopathy European journal of trauma and emergency surgery 2015;41 (4):413-420 [PubMed]
• Juffermans Nicole P., Walsh Timothy S. Introductionin: Nicole P. Juffermans, Timothy S. Walsh, editors. Transfusion in the Intensive Care Unit. New York: Springer; 2015. p. 1-4, ISBN 9783319087344; 9783319087351
• Harmon Matthew B. A., Itenov Theis S., Jensen Jens U., Juffermans Nicole P. Is fever control or improved survival the 'risk factor' for ventilator-associated pneumonia? Critical care (London, England) 2015;19 (1):208 [PubMed]
• Boshuizen Margit, Leopold Jan Hendrik, Zakharkina Tetyana, Knobel Hugo H., Weda Hans, Nijsen Tamara M. E., Vink Teunis J., Sterk Peter J., Schultz Marcus J., Bos Lieuwe D. J., Cremer Olaf L., Klein Klouwenberg Peter M. C., Ong David S. Y., Frencken Jos F., Bonten Marc J. M., Horn Janneke, Juffermans Nicole, van Hooijdonk Roosmarijn T. M., Huson Mischa A., Schouten Laura R. A., Straat Marleen, van Vught Lonneke A., Wiewel Maryse A., Witteveen Esther, Glas Gerie J., de Beer Friso M., Wieske Luuk, van der Poll Tom Levels of cytokines in broncho-alveolar lavage fluid, but not in plasma, are associated with levels of markers of lipid peroxidation in breath of ventilated ICU patients Journal of breath research 2015;9 (3):036010 [PubMed]
• Juffermans Nicole P., Schultz Marcus J. Microparticles: Still Far From Being the Ideal Biomarker for Ventilator-Associated Lung Injury Critical care medicine 2015;43 (12):2700-2701 [PubMed]
• van Boven W.J., Hermanns H., Juffermans N. P. New insights for transfusion triggers in cardiac surgery: editorial Netherlands journal of critical care 2015;21 (3):4-5
• Peters Anna L., van Hezel Maike E., Juffermans Nicole P., Vlaar Alexander P. J. Pathogenesis of non-antibody mediated transfusion-related acute lung injury from bench to bedside Blood reviews 2015;29 (1):51-61 [PubMed]
• van Hooijdonk Roosmarijn T. M., Leopold Jan Hendrik, Winters Tineke, Binnekade Jan M., Juffermans Nicole P., Horn Janneke, Fischer Johan C., van Dongen-Lases Edmée C., Schultz Marcus J. Point accuracy and reliability of an interstitial continuous glucose-monitoring device in critically ill patients: a prospective study Critical care (London, England) 2015;19 (1):34 [PubMed]
• van der Hoeven Sophia M., Binnekade Jan M., de Borgie Corianne A. J. M., Bosch Frank H., Endeman Henrik, Horn Janneke, Juffermans Nicole P., van der Meer Nardo J. M., Merkus Maruschka P., Moeniralam Hazra S., van Silfhout Bart, Slabbekoorn Mathilde, Stilma Willemke, Wijnhoven Jan Willem, Schultz Marcus J., Paulus Frederique Preventive nebulization of mucolytic agents and bronchodilating drugs in invasively ventilated intensive care unit patients (NEBULAE): study protocol for a randomized controlled trial Trials 2015;16 (1):389 [PubMed]
• Simonis Fabienne D., Binnekade Jan M., Braber Annemarije, Gelissen Harry P., Heidt Jeroen, Horn Janneke, Innemee Gerard, de Jonge Evert, Juffermans Nicole P., Spronk Peter E., Steuten Lotte M., Tuinman Pieter Roel, Vriends Marijn, de Vreede Gwendolyn, de Wilde Rob B., Serpa Neto Ary, Gama de Abreu Marcelo, Pelosi Paolo, Schultz Marcus J. PReVENT--protective ventilation in patients without ARDS at start of ventilation: study protocol for a randomized controlled trial Trials 2015;16 (1):226 [PubMed]
• Oei Gezina Tanya Mei Ling, Aslami Hamid, Kerindongo Raphaela Priscilla, Steenstra Renske Johanna, Beurskens Charlotte Jacqueline Peter, Tuip-de Boer Anita Maria, Juffermans Nicole Petra, Hollmann Markus Werner, Preckel Benedikt, Weber Nina Claudia Prolonged helium postconditioning protocols during early reperfusion do not induce cardioprotection in the rat heart in vivo: role of inflammatory cytokines Journal of immunology research 2015;2015:216798 [PubMed]
• Balvers Kirsten, Wirtz Mathijs R., van Dieren Susan, Goslings J. Carel, Juffermans Nicole P. Risk factors for trauma-induced coagulopathy- and transfusion-associated multiple organ failure in severely injured trauma patients Frontiers in Medicine 2015;2:24 [PubMed]
• van Vessem Denise J., Juffermans Nicole P., Bouman Catherine S. C., van Hest Reinier M. The Area Under the Concentration-Time Curve Is a Better Estimate for Vancomycin Exposure Than Trough Levels Critical care medicine 2015;43 (9):E401 [PubMed]
• Beurskens Charlotte J. P., Wösten-van Asperen Roelie M., Preckel Benedikt, Juffermans Nicole P. The potential of heliox as a therapy for acute respiratory distress syndrome in adults and children: a descriptive review Respiration; international review of thoracic diseases 2015;89 (2):166-174 [PubMed]
• Juffermans Nicole P., Walsh Timothy S. Transfusion in the Intensive Care UnitNew York: Springer; 2015. ISBN 9783319087344; 9783319087351
• Müller Marcella C., Arbous M. Sesmu, Spoelstra-de Man Angelique M., Vink Roel, Karakus Atilla, Straat Marleen, Binnekade Jan M., de Jonge Evert, Vroom Margreeth B., Juffermans Nicole P. Transfusion of fresh-frozen plasma in critically ill patients with a coagulopathy before invasive procedures: a randomized clinical trial (CME) Transfusion 2015;55 (1):26-35; quiz 25 [PubMed]
• Vlaar Alexander P. J., Juffermans Nicole P. Transfusion-Related Acute Lung Injuryin: Nicole P. Juffermans, Timothy S. Walsh, editors. Transfusion in the Intensive Care Unit. New York: Springer; 2015. p. 161-169, ISBN 9783319087344; 9783319087351

2014

• Serpa Neto Ary, Simonis Fabienne D., Barbas Carmen S. V., Biehl Michelle, Determann Rogier M., Elmer Jonathan, Friedman Gilberto, Gajic Ognjen, Goldstein Joshua N., Horn Janneke, Juffermans Nicole P., Linko Rita, de Oliveira Roselaine Pinheiro, Sundar Sugantha, Talmor Daniel, Wolthuis Esther K., de Abreu Marcelo Gama, Pelosi Paolo, Schultz Marcus J. Association between tidal volume size, duration of ventilation, and sedation needs in patients without acute respiratory distress syndrome: an individual patient data meta-analysis Intensive care medicine 2014;40 (7):950-957 [PubMed]
• Beurskens Charlotte J., Horn Janneke, de Boer Anita M. Tuip, Schultz Marcus J., van Leeuwen Ester Mm, Vroom Margreeth B., Juffermans Nicole P. Cardiac arrest patients have an impaired immune response, which is not influenced by induced hypothermia Critical care (London, England) 2014;18 (4):R162 [PubMed]
• Müller Marcella C. A. Coagulopathy and plasma transfusion in critically ill patients 2014. 342p. ISBN 9789461087263. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Vroom M. B.; Co-supervisor: Juffermans N. P.)
• Müller Marcella C. A., Tuinman Pieter R., Vlaar Alexander P., Tuip Anita M., Maijoor Kelly, Achouiti Achmed, van T Veer Cornelis, Vroom Margreeth B., Juffermans Nicole P. Contribution of damage-associated molecular patterns to transfusion-related acute lung injury in cardiac surgery Blood transfusion 2014;12 (3):368-375 [PubMed]
• van den Bosch Caroline M. A., Hulscher Marlies E. J. L., Natsch Stephanie, Gyssens Inge C., Prins Jan M., Geerlings Suzanne E., Bax H. I., Schippers E. F., van Assen S., Ang C. W., Sturm P., van der Meer Y. G., Boermeester M. A., Schouten J. A., Pickkers P., Janssen J. J. W. M., Blijlevens N. M. A., Juffermans N. P. Development of quality indicators for antimicrobial treatment in adults with sepsis BMC infectious diseases 2014;14 (1):345 [PubMed]
• Müller M. C. A., de Haan R. J., Vroom M. B., Juffermans N. P. Evaluation of a multi-center randomised clinical trial on prophylactic transfusion of fresh frozen plasma: implications for future trials Transfusion medicine (Oxford, England) 2014;24 (5):292-296 [PubMed]
• Beurskens Charlotte J., Brevoord Daniel, Lagrand Wim K., van den Bergh Walter M., Vroom Margreeth B., Preckel Benedikt, Horn Janneke, Juffermans Nicole P. Heliox Improves Carbon Dioxide Removal during Lung Protective Mechanical Ventilation Critical care research and practice 2014;2014:954814 [PubMed]
• Glas Gerie J., Muller Johannes, Binnekade Jan M., Cleffken Berry, Colpaert Kirsten, Dixon Barry, Juffermans Nicole P., Knape Paul, Levi Marcel M., Loef Bert G., Mackie David P., Malbrain Manu, Schultz Marcus J., van der Sluijs Koenraad F. HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial Trials 2014;15 (1):91 [PubMed]
• Beurskens Charlotte J., Aslami Hamid, de Beer Friso M., Roelofs Joris J. T. H., Vroom Margreeth B., Juffermans Nicole P. Mechanical ventilation with heliox in an animal model of acute respiratory distress syndrome Intensive Care Medicine Experimental 2014;2 (1):13 [PubMed]
• Müller Marcella C. A., Tuinman Pieter R., van der Sluijs Koenraad F., Boon Louis, Roelofs Joris J., Vroom Margreeth B., Juffermans Nicole P. Methylprednisolone fails to attenuate lung injury in a mouse model of transfusion related acute lung injury Transfusion 2014;54 (4):996-1001 [PubMed]
• Jong Willeke M. C., Leemans Jaklien C., Weber Nina C., Juffermans Nicole P., Schultz Marcus J., Hollmann Markus W., Zuurbier Coert J. Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression International journal of cardiology 2014;177 (1):41-43 [PubMed]
• de Beer F. M., Aslami H., Hoeksma J., van Mierlo G., Wouters D., Zeerleder S., Roelofs J. J. T. H., Juffermans N. P., Schultz M. J., Lagrand W. K. Plasma-derived human C1-esterase inhibitor does not prevent mechanical ventilation-induced pulmonary complement activation in a rat model of Streptococcus pneumoniae pneumonia Cell biochemistry and biophysics 2014;70 (2):795-803 [PubMed]
• Beurskens Charlotte J. P. Potential therapeutic strategies aimed at reducing the intensity of mechanical ventilation in ARDS 2014. 187p. ISBN 9789088918797. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schultz M. J., Vroom M. B.; Co-supervisor: Juffermans N. P.)
• Hagemo Jostein S., Stanworth Simon, Juffermans Nicole P., Brohi Karim, Cohen Mitchell, Johansson Pär I., Røislien Jo, Eken Torsten, Næss Paal A., Gaarder Christine Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study Critical care (London, England) 2014;18 (2):R52 [PubMed]
• Helmerhorst Hendrik J. F., Schultz Marcus J., van der Voort Peter H. J., Bosman Robert J., Juffermans Nicole P., de Jonge Evert, van Westerloo David J. Self-reported attitudes versus actual practice of oxygen therapy by ICU physicians and nurses Annals of intensive care 2014;4:23 [PubMed]
• van der Vaart Thomas W., van Thiel Pieter P. A. M., Juffermans Nicole P., van Vugt Michèle, Geerlings Suzanne E., Grobusch Martin P., Goorhuis Abraham Severe murine typhus with pulmonary system involvement Emerging infectious diseases 2014;20 (8):1375-1377 [PubMed]
• Müller M. C. A., Stroo I., Wouters D., Zeerleder S. S., Roelofs J. J. T. H., Boon L., Vroom M. B., Juffermans N. P. The effect of C1-inhibitor in a murine model of transfusion-related acute lung injury Vox sanguinis 2014;107 (1):71-75 [PubMed]
• Balvers Kirsten, Muller Marcella C. A., Juffermans Nicole P. The utility of ROTEM to detect coagulation disorders in non-bleeding ICU patients Annual Update in Intensive Care and Emergency Medicine 2014;2014
• Müller Marcella C. A., Balvers Kirsten, Binnekade Jan M., Curry Nicola, Stanworth Simon, Gaarder Christine, Kolstadbraaten Knut M., Rourke Claire, Brohi Karim, Goslings J. Carel, Juffermans Nicole P. Thromboelastometry and organ failure in trauma patients: a prospective cohort study Critical care (London, England) 2014;18 (6):687 [PubMed]
• Müller Marcella C., Meijers Joost C. M., Vroom Margreeth B., Juffermans Nicole P. Utility of thromboelastography and/or thromboelastometry in adults with sepsis: a systematic review Critical care (London, England) 2014;18 (1):R30 [PubMed]

2013

• Tuinman Pieter R., Binnekade Jan M., Juffermans Nicole P. Antiplatelet Therapy in Bleeding Trauma Patients: Tales of the Unexpected Critical care medicine 2013;41 (8):E187-E188 [PubMed]
• Aslami Hamid, Beurskens Charlotte J. P., de Beer Friso M., Kuipers Maria T., Roelofs Joris J. T. H., Hegeman Maria A., van der Sluijs Koen F., Schultz Marcus J., Juffermans Nicole P. A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion Cytokine 2013;61 (2):614-621 [PubMed]
• Mooij C.M., Beurskens Charlotte J., Juffermans Nicole P. Energy expenditure in different patient populations on intensive care Netherlands journal of critical care 2013;17 (3):3-9
• Tuinman Pieter R. Experimental strategies directed at inflammation and coagulation in ARDS and TRALI 2013. 171p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schultz M. J.; Co-supervisor: Juffermans N. P.)
• Aslami Hamid Explorations of the therapeutic potential of influencing metabolism during critical illness 2013. 317p. ISBN 9789461083951. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schultz M. J.; Co-supervisor: Juffermans N. P.)
• Schultz Marcus J., Juffermans Nicole P., Matthay Michael A. From protective ventilation to super-protective ventilation for acute respiratory distress syndrome Intensive care medicine 2013;39 (5):963-965 [PubMed]
• Beurskens Charlotte J., Aslami Hamid, de Beer Friso M., Vroom Margreeth B., Preckel Benedikt, Horn Janneke, Juffermans Nicole P. Heliox allows for lower minute volume ventilation in an animal model of ventilator-induced lung injury PLoS ONE 2013;8 (10):e78159 [PubMed]
• Tuinman Pieter R., Müller Marcella C., Jongsma Geartsje, Hegeman Maria A., Juffermans Nicole P. High-dose acetylsalicylic acid is superior to low-dose as well as to clopidogrel in preventing lipopolysaccharide-induced lung injury in mice Shock (Augusta, Ga.) 2013;40 (4):334-338 [PubMed]
• Kuipers Maria T., Vogl Thomas, Aslami Hamid, Jongsma Geartsje, van den Berg Elske, Vlaar Alexander P. J., Roelofs Joris J. T. H., Juffermans Nicole P., Schultz Marcus J., van der Poll Tom, Roth Johannes, Wieland Catharina W. High levels of S100A8/A9 proteins aggravate ventilator-induced lung injury via TLR4 signaling PLoS ONE 2013;8 (7):e68694 [PubMed]
• Aslami Hamid, Pulskens Wilco P., Kuipers Maria T., Bos Aafkeline P., van Kuilenburg André B. P., Wanders Ronald J. A., Roelofsen Jeroen, Roelofs Joris J. T. H., Kerindongo Raphaela P., Beurskens Charlotte J. P., Schultz Marcus J., Kulik Wim, Weber Nina C., Juffermans Nicole P. Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status PLoS ONE 2013;8 (5):e63497 [PubMed]
• Juffermans N. P. Predicting mortality in the critically ill: a tricky enterprise Netherlands journal of medicine 2013;71 (9):447 [PubMed]
• Müller Marcella C. A., Juffermans N. P. Risk factors for Transfusion Related Lung Injury in ICU patientsHeidelberg, Germany: Springer; 2013. (Annual Update in Intensive Care and Emergency Medicine)
• Tuinman Pieter R., Cornet Alexander D., Kuipers Maria T., Vlaar Alexander P., Schultz Marcus J., Beishuizen Albertus, Groeneveld A. B. Johan, Juffermans Nicole P. Soluble receptor for advanced glycation end products as an indicator of pulmonary vascular injury after cardiac surgery BMC pulmonary medicine 2013;13 (1):76 [PubMed]
• Nielsen Niklas, Wetterslev Jørn, Cronberg Tobias, Erlinge David, Gasche Yvan, Hassager Christian, Horn Janneke, Hovdenes Jan, Kjaergaard Jesper, Kuiper Michael, Pellis Tommaso, Stammet Pascal, Wanscher Michael, Wise Matt P., Åneman Anders, al-Subaie Nawaf, Boesgaard Søren, Bro-Jeppesen John, Brunetti Iole, Bugge Jan Frederik, Hingston Christopher D., Juffermans Nicole P., Koopmans Matty, Køber Lars, Langørgen Jørund, Lilja Gisela, Møller Jacob Eifer, Rundgren Malin, Rylander Christian, Smid Ondrej, Werer Christophe, Winkel Per, Friberg Hans, Pellis Thomas, Køber Lars V., Annane Djillali, Wernerman Jan, Lange Theis, Karlsson Ulla-Britt, Jergle-Almqvist Liz, Grevstad Berit, Whitfield Kate, Micallef Sharon, Glass Parisa, Myburgh John, Saxena Manoj, Stewart Antony, Finfer Simon, Bishop Gillian, Rajbhandari Dorrilyn Targeted temperature management at 33°C versus 36°C after cardiac arrest New England journal of medicine 2013;369 (23):2197-2206 [PubMed]
• Hegeman Maria A., Hemmes Sabrine N. T., Kuipers Maria T., Bos Lieuwe D. J., Jongsma Geartsje, Roelofs Joris J. T. H., van der Sluijs Koenraad F., Juffermans Nicole P., Vroom Margreeth B., Schultz Marcus J. The Extent of Ventilator-Induced Lung Injury in Mice Partly Depends on Duration of Mechanical Ventilation Critical care research and practice 2013;2013:435236 [PubMed]
• Vlaar Alexander P. J., Juffermans Nicole P. Transfusiegerelateerde acute longschade Nederlands tijdschrift voor geneeskunde 2013;157 (11):A5524 [PubMed]
• Tuinman Pieter R., Muller Marcella C., Juffermans Nicole P. Transfusion in myocardial infarction: bloodcurdling? JAMA internal medicine 2013;173 (12):1156-1157 [PubMed]
• Vlaar Alexander P. J., Juffermans Nicole P. Transfusion-related acute lung injury: a clinical review Lancet 2013;382 (9896):984-994 [PubMed]
• Vermeij Jan-Dirk, Aslami Hamid, Fluiter Kees, Roelofs Joris J., van den Bergh Walter M., Juffermans Nicole P., Schultz Marcus J., van der Sluijs Koen, van de Beek Diederik, van Westerloo David J. Traumatic brain injury in rats induces lung injury and systemic immune suppression Journal of neurotrauma 2013;30 (24):2073-2079 [PubMed]

2012

• Vlaar Alexander P. J., Juffermans Nicole P., de Korte Dirk Bioactive lipids from stored cellular blood components: in vitro method is crucial for proper interpretation In reply Transfusion 2012;52 (5):1157-1158 [PubMed]
• Beurskens Charlotte J. P., Juffermans Nicole P. Changes in the inflammatory response following cardiac arrest: A matter of ischemia/reperfusion or induced hypothermia? Critical care medicine 2012;40 (11):3105 [PubMed]
• Tuinman Pieter R., Schultz Marcus J., Juffermans Nicole P. Coagulopathy as a Therapeutic Target for TRALI: Rationale and Possible Sites of Action Current pharmaceutical design 2012;18 (22):3267-3272 [PubMed]
• Hofstra Jorrit J., Vlaar Alexander P. J., Prins David J., Koh Gavin, Levi Marcel, Schultz Marcus J., Binnekade Jan M., Juffermans Nicole P. Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome - a retrospective propensity matched cohort study BMC pulmonary medicine 2012;12 (1):43 [PubMed]
• Beurskens Charlotte J. P., Aslami Hamid, Kuipers Maria T., Horn Janneke, Vroom Margreeth B., van Kuilenburg André B. P., Roelofs Joris J. T. H., Schultz Marcus J., Juffermans Nicole P. Induced hypothermia is protective in a rat model of pneumococcal pneumonia associated with increased adenosine triphosphate availability and turnover Critical care medicine 2012;40 (3):919-926 [PubMed]
• Koh Gavin C. K. W., Vlaar Alexander P. J., Hofstra Jorrit J., de Jong H. Katrien, van Nierop Samuel, Peacock Sharon J., Wiersinga W. Joost, Schultz Marcus J., Juffermans Nicole P. In the critically ill patient, diabetes predicts mortality independent of statin therapy but is not associated with acute lung injury: A cohort study Critical care medicine 2012;40 (6):1835-1843 [PubMed]
• Vlaar A. P. J., Kuipers M. T., Hofstra J. J., Wolthuis E. K., Wieland C. W., Roelofs J. J. T. H., Boon L., Schultz M. J., Lutter R., Juffermans N. P. Mechanical ventilation and the titer of antibodies as risk factors for the development of transfusion-related lung injury Critical care research and practice 2012;2012:720950 [PubMed]
• Aslami Hamid, Kuipers Maria T., Beurskens Charlotte J. P., Roelofs Joris J. T. H., Schultz Marcus J., Juffermans Nicole P. Mild hypothermia reduces ventilator-induced lung injury, irrespective of reducing respiratory rate Translational research 2012;159 (2):110-117 [PubMed]
• Tuinman Pieter R., Dixon Barry, Levi Marcel, Juffermans Nicole P., Schultz Marcus J. Nebulized anticoagulants for acute lung injury - a systematic review of preclinical and clinical investigations Critical care (London, England) 2012;16 (2):R70 [PubMed]
• Kuipers Maria T., Aslami Hamid, Vlaar Alexander P. J., Juffermans Nicole P., Tuip-de Boer Anita M., Hegeman Maria A., Jongsma Geartsje, Roelofs Joris J. T. H., van der Poll Tom, Schultz Marcus J., Wieland Catharina W. Pre-Treatment with Allopurinol or Uricase Attenuates Barrier Dysfunction but Not Inflammation during Murine Ventilator-Induced Lung Injury PLoS ONE 2012;7 (11):e50559 [PubMed]
• Straat Marleen, van Bruggen Robin, de Korte Dirk, Juffermans Nicole P. Red Blood Cell Clearance in Inflammation Transfusion medicine and hemotherapy 2012;39 (5):353-360 [PubMed]
• Wolthuis Esther K., Vlaar Alexander P. J., Choi Goda, Roelofs Joris J. T. H., Levi Marcel, Juffermans Nicole P., Schultz Marcus J. Relative Tissue Factor Deficiency Attenuates Ventilator-Induced Coagulopathy but Does Not Protect against Ventilator-Induced Lung Injury in Mice Critical care research and practice 2012;2012:130410 [PubMed]
• Hofstra J.-J. H. Systemic and local and local anticoagulant strategies for pulmonary inflammation and coagulopathy 2012. 287p. ISBN 9789088914065. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schultz M. J., Levi M. M.; Co-supervisors: Vroom M. B., Juffermans N. P.)
• Aslami Hamid, Juffermans Nicole P. Targetting mitochondrial function in sepsis Netherlands journal of critical care 2012;16 (14):117
• Juffermans Nicole P., Vlaar Alexander P. J., Prins David J., Goslings J. Carel, Binnekade Jan M. The age of red blood cells is associated with bacterial infections in critically ill trauma patients Blood transfusion 2012;10 (3):290-295 [PubMed]
• Tuinman P. R., Vlaar A. P., Binnenkade J. M., Juffermans N. P. The effect of aspirin in transfusion-related acute lung injury in critically ill patients Anaesthesia 2012;67 (6):594-599 [PubMed]
• Vlaar Alexander P. J., Cornet Alexander D., Hofstra Jorrit J., Porcelijn Leendert, Beishuizen Albertus, Kulik Willem, Vroom Margreeth B., Schultz Marcus J., Groeneveld A. B. Johan, Juffermans Nicole P. The effect of blood transfusion on pulmonary permeability in cardiac surgery patients: a prospective multicenter cohort study Transfusion 2012;52 (1):82-90 [PubMed]
• Müller Marcella C. A., Juffermans Nicole P. Transfusion-related acute lung injury: a preventable syndrome? Expert review of hematology 2012;5 (1):97-106 [PubMed]
• Vlaar Alexander P. J., Hofstra Jorrit J., Determann Rogier M., Veelo Denise P., Paulus Frederique, Levi Marcel, Zeerleder Sacha, Vroom Margreeth B., Schultz Marcus J., Juffermans Nicole P. Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: A prospective nested case-control study Critical care medicine 2012;40 (10):2813-2820 [PubMed]

2011

• Vlaar Alexander P. J., Kulik Wim, Nieuwland Rienk, Peters Charlotte P., Tool Anton T. J., van Bruggen Robin, Juffermans Nicole P., de Korte Dirk Accumulation of bioactive lipids during storage of blood products is not cell but plasma derived and temperature dependent Transfusion 2011;51 (11):2358-2366 [PubMed]
• Tuinman Pieter R., Vlaar Alexander P., Cornet Alexander D., Hofstra Jorrit J., Levi Marcel, Meijers Joost C. M., Beishuizen Albertus, Schultz Marcus J., Groeneveld Ab Johan, Juffermans Nicole P. Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study Critical care (London, England) 2011;15 (1):R59 [PubMed]
• Aslami Hamid, Schultz Marcus J., Juffermans Nicole P. Hydrogen sulfide: a hot molecule Anesthesiology 2011;115 (5):921-922 [PubMed]
• Tuinman P. R., Gerards M. C., Jongsma G., Vlaar A. P., Boon L., Juffermans N. P. Lack of evidence of CD40 ligand involvement in transfusion-related acute lung injury Clinical and experimental immunology 2011;165 (2):278-284 [PubMed]
• Wolthuis Esther K., Vlaar Alexander P. J., Hofstra Jorrit-Jan H., Roelofs Joris J. T. H., de Waard Vivian, Juffermans Nicole P., Schultz Marcus J. Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury Critical care research and practice 2011;2011:217896 [PubMed]
• Tuinman Pieter R., Juffermans Nicole P. Soluble CD40 ligand, a mediator of sepsis or of transfusion-related adverse effects? Critical care (London, England) 2011;15 (3):429 [PubMed]
• Vlaar Alexander P. J., Binnekade Jan M., Juffermans Nicole P. The authors reply: Risk factors for transfusion-related acute lung injury: Improper analysis of matched data Critical care medicine 2011;39 (3):611 [PubMed]
• Vlaar Alexander P. J., Hofstra Jorrit J., Determann Rogier M., Veelo Denise P., Paulus Frederique, Kulik Wim, Korevaar Johanna, de Mol Bas A., Koopman Marianne M. W., Porcelijn Leendert, Binnekade Jan M., Vroom Margreeth B., Schultz Marcus J., Juffermans Nicole P. The incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of cardiac surgery patients: a prospective nested case-control study Blood 2011;117 (16):4218-4225 [PubMed]
• Vlaar A. P., Straat M., Juffermans N. P. The relation between aged blood products and onset of transfusion-related acute lung injury. A review of pre-clinical data Clinical laboratory 2011;57 (3-4):267-272 [PubMed]
• Müller Marcella C. A., de Jonge Evert, Arbous M. Sesmu, Spoelstra-de Man Angelique M. E., Karakus Atilla, Vroom Margreeth B., Juffermans Nicole P. Transfusion of fresh frozen plasma in non-bleeding ICU patients--TOPIC trial: study protocol for a randomized controlled trial Trials 2011;12 (1):266 [PubMed]
• Juffermans Nicole P., Prins David J., Vlaar Alexander P. J., Nieuwland Rienk, Binnekade Jan M. TRANSFUSION-RELATED RISK OF SECONDARY BACTERIAL INFECTIONS IN SEPSIS PATIENTS: A RETROSPECTIVE COHORT STUDY Shock (Augusta, Ga.) 2011;35 (4):355-359 [PubMed]

2010

• Juffermans Nicole P., Vervloet Marc G., Daemen-Gubbels Catharina Rg, Binnekade Jan M., Jong Martin de, Groeneveld Ab Johan A dose-finding study of methylene blue to inhibit nitric oxide actions in the hemodynamics of human septic shock Nitric oxide 2010;22 (4):275-280 [PubMed]
• Müller Marcella C. A., Juffermans Nicole P. Anemia and blood transfusion and outcome on the intensive care unit Critical care (London, England) 2010;14 (1):438 [PubMed]
• van der Sluijs Koenraad F., van der Poll Tom, Lutter René, Juffermans Nicole P., Schultz Marcus J. Bench-to-bedside review: Bacterial pneumonia with influenza - pathogenesis and clinical implications Critical care (London, England) 2010;14 (2):219 [PubMed]
• Müller Marcella C. A., Lagarde Sjoerd M., Germans Menno R., Juffermans Nicole P. Cerebral air embolism after arthrography of the ankle Medical science monitor 2010;16 (7):CS92-CS94 [PubMed]
• Aslami H., Juffermans N. P. Induction of a hypometabolic state during critical illness - a new concept in the ICU? Netherlands journal of medicine 2010;68 (5):190-198 [PubMed]
• Vlaar A. P. J., Wolthuis E. K., Hofstra J. J., Roelofs J. J. T. H., Boon L., Schultz M. J., Lutter R., Juffermans N. P. Mechanical ventilation aggravates transfusion-related acute lung injury induced by MHC-I class antibodies Intensive care medicine 2010;36 (5):879-887 [PubMed]
• Schultz Marcus J., Juffermans Nicole P. Prevention of VAP: "WHAP" should we do? Critical care medicine 2010;38 (2):706-707 [PubMed]
• van Westerloo D. J., Juffermans N. P. Red and wet Netherlands journal of medicine 2010;68 (5):228-+ [PubMed]
• Vlaar Alexander P. J., Binnekade Jan M., Prins David, van Stein Danielle, Hofstra Jorrit J., Schultz Marcus J., Juffermans Nicole P. Risk factors and outcome of transfusion-related acute lung injury in the critically ill: A nested case-control study Critical care medicine 2010;38 (3):771-778 [PubMed]
• Cornet Alexander D., Hofstra Jorrit J., Swart Eleonora L., Girbes Armand R. J., Juffermans Nicole P. Sildenafil attenuates pulmonary arterial pressure but does not improve oxygenation during ARDS Intensive care medicine 2010;36 (5):758-764 [PubMed]
• Vlaar Alexander P. J., Hofstra Jorrit J., Levi Marcel, Kulik Willem, Nieuwland Rienk, Tool Anton T. J., Schultz Marcus J., de Korte Dirk, Juffermans Nicole P. Supernatant of Aged Erythrocytes Causes Lung Inflammation and Coagulopathy in a "Two-Hit" In Vivo Syngeneic Transfusion Model Anesthesiology 2010;113 (1):92-103 [PubMed]
• Vlaar Alexander P. J., Hofstra Jorrit J., Kulik Wim, van Lenthe Henk, Nieuwland Rienk, Schultz Marcus J., Levi Marcel M., Roelofs Joris J. T. H., Tool Anton T. J., de Korte Dirk, Juffermans Nicole P. Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model Blood 2010;116 (8):1360-1368 [PubMed]
• Aslami Hamid, Heinen André, Roelofs Joris J. T. H., Zuurbier Coert J., Schultz Marcus J., Juffermans Nicole P. Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury Intensive care medicine 2010;36 (11):1946-1952 [PubMed]
• Vlaar Alexander P. J., Porcelijn Leendert, van Rooijen-Schreurs Ingeborgh H. M., Lardy Neubury Maxton, Kersten Marie Jose, Juffermans Nicole P. The divergent clinical presentations of transfusion-related acute lung injury illustrated by two case reports Medical science monitor 2010;16 (10):CS129-CS134 [PubMed]
• Aslami Hamid, Binnekade Jan M., Horn Janneke, Huissoon Sandra, Juffermans Nicole P. The effect of induced hypothermia on respiratory parameters in mechanically ventilated patients Resuscitation 2010;81 (12):1723-1725 [PubMed]
• Vlaar Alexander P., Wortel Kim, Binnekade Jan M., van Oers Marinus H. J., Beckers Erik, Gajic Ognjen, Schultz Marcus J., Juffermans Nicole P. The practice of reporting transfusion-related acute lung injury: a national survey among clinical and preclinical disciplines Transfusion 2010;50 (2):443-451 [PubMed]
• Cornet Alexander D., Juffermans Nicole P. There is no place (yet) for routine administration of sildenafil to patients with ARDS Intensive care medicine 2010;36 (6):1104-1105
• Juffermans Nicole P. Transfusion-related acute lung injury: emerging importance of host factors and implications for management Expert review of hematology 2010;3 (4):459-+ [PubMed]
• Vlaar Alexander P. J. Transfusion-related acute lung injury in the critically ill. A translational approach 2010. 371p. ISBN 9789090256550. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Vroom M. B., Schultz M. J.; Co-supervisor: Juffermans N. P.)

2009

• Schultz Marcus J., Juffermans Nicole P., van der Poll Tom A new twist on the legend of granulocyte colony-stimulating factor in acute lung injury? Critical care medicine 2009;37 (4):1506-1507 [PubMed]
• Vlaar A. P. J., in der Maur A. L., Binnekade J. M., Schultz M. J., Juffermans N. P. A survey of physicians' reasons to transfuse plasma and platelets in the critically ill: a prospective single-centre cohort study Transfusion medicine (Oxford, England) 2009;19 (4):207-212 [PubMed]
• Vlaar Alexander P. J., In der Maur Anne L., Binnekade Jan M., Schultz Marcus J., Juffermans Nicole P. Determinants of transfusion decisions in a mixed Medical-Surgical Intensive Care Unit: a prospective cohort study Blood transfusion 2009;7 (2):106-110 [PubMed]
• Vlaar A. P. J., Honselaar W. B., Binnekade J. M., Groeneveld A. B., Spronk P. E., Schultz M. J., Juffermans N. P. Diagnosing acute lung injury in the critically ill: a national survey among critical care physicians Acta anaesthesiologica Scandinavica 2009;53 (10):1293-1299 [PubMed]
• Wolthuis Esther K., Vlaar Alexander Pj, Choi Goda, Roelofs Joris J. T. H., Juffermans Nicole P., Schultz Marcus J. Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice Critical care (London, England) 2009;13 (1):R1 [PubMed]
• Aslami Hamid, Schultz Marcus J., Juffermans Nicole P. Potential Applications of Hydrogen Sulfide-Induced Suspended Animation Current medicinal chemistry 2009;16 (10):1295-1303 [PubMed]
• Wolthuis Esther K., Vlaar Alexander P. J., Choi Goda, Roelofs Joris J. T. H., Haitsma Jack J., van der Poll Tom, Juffermans Nicole P., Zweers Machteld M., Schultz Marcus J. Recombinant human soluble tumor necrosis factor-alpha receptor fusion protein partly attenuates ventilator-induced lung injury Shock (Augusta, Ga.) 2009;31 (3):262-266 [PubMed]
• Vlaar Alexander P. J., de Korte Dirk, Juffermans Nicole P. The Aged Erythrocyte: Key Player in Cancer Progression, but Also in Infectious and Respiratory Complications of Blood Transfusion? Anesthesiology 2009;111 (2):444 [PubMed]
• Vlaar A. P., Schultz M. J., Juffermans N. P. Transfusion-related acute lung injury: a change of perspective Netherlands journal of medicine 2009;67 (10):320-326 [PubMed]

2008

• Schultz Marcus J., Juffermans Nicole P. Maldistribution of interalveolar perfusion--one early step in the pathogenesis of lung injury? Critical care medicine 2008;36 (2):639-640 [PubMed]
• Vlaar Alexander P. J., Binnekade Jan M., Schultz Marcus J., Juffermans Nicole P., Koopman Maria M. W. Preventing TRALI: Ladies first, what follows? Critical care medicine 2008;36 (12):3283-3284 [PubMed]
• Hofstra Jorrit-Jan H., Juffermans Nicole P., Schultz Marcus J., Zweers Machteld M. Pulmonary coagulopathy as a new target in lung injury--a review of available pre-clinical models Current medicinal chemistry 2008;15 (6):588-595 [PubMed]
• Hofstra Jorrit-Jan H., Haitsma Jack J., Juffermans Nicole P., Levi Marcel, Schultz Marcus J. The Role of Bronchoalveolar Hemostasis in the Pathogenesis of Acute Lung Injury Seminars in thrombosis and hemostasis 2008;34 (5):475-484 [PubMed]
• Vlaar A. P. J., Schultz M. J., Juffermans N. P. Transfusiegerelateerde acute longbeschadiging (TRALI) in Nederland in 2002-2005 Nederlands tijdschrift voor geneeskunde 2008;152 (35):1945-1946 [PubMed]
• Schultz Marcus J., Determann Rogier M., Juffermans Nicole P. Ventilator-associated pneumonia prevention: WHAP, positive end-expiratory pressure, or both? Critical care medicine 2008;36 (8):2441-2442 [PubMed]

2007

• Vlaar Alexander P. J., Zweers Machteld M., Schultz Marcus J., Juffermans Nicole P. Developing specific therapeutic strategies for transfusion-related acute lung injury. An overview of potentially useful animal models Cardiovascular & hematological agents in medicinal chemistry 2007;5 (4):319-326 [PubMed]
• Juffermans Nicole P. Hypothermia in acute lung injury: reduction of barotrauma or biotrauma? Anesthesia and analgesia 2007;105 (5):1513-4; author reply 1514 [PubMed]
• Juffermans Nicole P. The pathogenesis of Tranfusion-Related Acute Lung Injury in Critically Ill patients Netherlands journal of critical care 2007;11:302-305

2006

• Juffermans N. P., Rijneveld A. W., Zweegman S., Spijkstra J. J. Twee patiënten met lactaatacidose en hypoglykemie als uiting van een lymfoom Nederlands tijdschrift voor geneeskunde 2006;150 (50):2770-2773 [PubMed]

2005

• Juffermans N. P., Jager A., Kersten M. J., van Oers M. H., Hommes D. W. Epstein-Barr-virus-gerelateerde lymfomen bij patiënten met inflammatoire darmziekte Nederlands tijdschrift voor geneeskunde 2005;149 (33):1859-1863 [PubMed]

2002

• Camoglio Luisa, Juffermans Nicole P., Peppelenbosch Maikel, te Velde Anje A., ten Kate Fibo J., van Deventer Sander J. H., Kopf Manfred Contrasting roles of IL-12p40 and IL-12p35 in the development of hapten-induced colitis European journal of immunology 2002;32 (1):261-269 [PubMed]
• Juffermans Nicole P., Leemans Jaklien C., Florquin Sandrine, Verbon Annelies, Kolk Arend H., Speelman Peter, van Deventer Sander J. H., van der Poll Tom CpG oligodeoxynucleotides enhance host defense during murine tuberculosis Infection and immunity 2002;70 (1):147-152 [PubMed]
• Juffermans Nicole P., Verbon Annelies, van der Poll Tom Diabetes insipidus as a complication of cryptococcal meningitis in an HIV-infected patient Scandinavian journal of infectious diseases 2002;34 (5):397-398 [PubMed]
• Juffermans Nicole P., Weijer Sebastiaan, Verbon Annelies, Speelman Peter, van der Poll Tom Expression of human immunodeficiency virus coreceptors CXC chemokine receptor 4 and CC chemokine receptor 5 on monocytes is down-regulated during human endotoxemia Journal of infectious diseases 2002;185 (7):986-989 [PubMed]

2001

• Juffermans N. P., Dekkers P. E., Verbon A., Speelman P., van Deventer S. J., van der Poll T. Concurrent upregulation of urokinase plasminogen activator receptor and CD11b during tuberculosis and experimental endotoxemia Infection and immunity 2001;69 (8):5182-5185 [PubMed]
• Leemans J. C., Juffermans N. P., Florquin S., van Rooijen N., Vervoordeldonk M. J., Verbon A., van Deventer S. J., van der Poll T. Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice Journal of immunology (Baltimore, Md. 2001;166 (7):4604-4611 [PubMed]
• van den Blink B., Juffermans N. P., ten Hove T., Schultz M. J., van Deventer S. J., van der Poll T., Peppelenbosch M. P. p38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivo Journal of immunology (Baltimore, Md. 2001;166 (1):582-587 [PubMed]
• Juffermans N. P., Speelman P., Verbon A., Veenstra J., Jie C., van Deventer S. J., van der Poll T. Patients with active tuberculosis have increased expression of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells Clinical infectious diseases 2001;32 (4):650-652 [PubMed]
• Juffermans N. P., Verbon A., Schultz M. J., Hack C. E., van Deventer S. J., Speelman P., van der Poll T. Thalidomide inhibits granulocyte responses in healthy humans after ex vivo stimulation with bacterial antigens Antimicrobial agents and chemotherapy 2001;45 (5):1547-1549 [PubMed]

2000

• Verbon A., Juffermans N. P., Speelman P., van Deventer S. J., ten Berge I. J., Guchelaar H. J., van der Poll T. A single oral dose of thalidomide enhances the capacity of lymphocytes to secrete gamma interferon in healthy humans Antimicrobial agents and chemotherapy 2000;44 (9):2286-2290 [PubMed]
• Dekkers P. E., Juffermans N. P., ten Hove T., de Jonge E., van Deventer S. J., van der Poll T. Endotoxin down-regulates monocyte and granulocyte interleukin-6 receptors without influencing gp130 expression in humans Journal of infectious diseases 2000;181 (3):1055-1061 [PubMed]
• Juffermans N. P., Dekkers P. E., Peppelenbosch M. P., Speelman P., van Deventer S. J., van der Poll T. Expression of the chemokine receptors CXCR1 and CXCR2 on granulocytes in human endotoxemia and tuberculosis: involvement of the p38 mitogen-activated protein kinase pathway Journal of infectious diseases 2000;182 (3):888-894 [PubMed]
• Dekkers P. E., Juffermans N. P., Hove T. t, de Jonge E., van Deventer S. J., van der Poll T. Granulocyte colony-stimulating factor receptors on granulocytes are down-regulated after endotoxin administration to healthy humans Journal of infectious diseases 2000;181 (6):2067-2070 [PubMed]
• Juffermans N. P., Florquin S., Camoglio L., Verbon A., Kolk A. H., Speelman P., van Deventer S. J., van der Poll T. Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis Journal of infectious diseases 2000;182 (3):902-908 [PubMed]
• Juffermans N. P., Verbon A., Belisle J. T., Hill P. J., Speelman P., van Deventer S. J., van der Poll T. Mycobacterial lipoarabinomannan induces an inflammatory response in the mouse lung. A role for interleukin-1 American journal of respiratory and critical care medicine 2000;162 (2 Part 1):486-489 [PubMed]
• Juffermans N. P., Verbon A., Olszyna D. P., van Deventer S. J., Speelman P., van der Poll T. Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans Journal of infectious diseases 2000;181 (5):1813-1816 [PubMed]
• Juffermans N. P., Paxton W. A., Dekkers P. E., Verbon A., de Jonge E., Speelman P., van Deventer S. J., van der Poll T. Up-regulation of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells during human endotoxemia and after stimulation with (myco)bacterial antigens: the role of cytokines Blood 2000;96 (8):2649-2654 [PubMed]

1999

• Juffermans N. P., Verbon A., van Deventer S. J., van Deutekom H., Belisle J. T., Ellis M. E., Speelman P., van der Poll T. Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan Infection and immunity 1999;67 (8):4295-4297 [PubMed]
• Verbon A., Juffermans N., van Deventer S. J., Speelman P., van Deutekom H., van der Poll T. Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment Clinical and experimental immunology 1999;115 (1):110-113 [PubMed]

1998

• Juffermans N., Verbon A., van der Meer J. T., Dankert J., van Steenwijk R. P., Speelman P. Karakterisering van 100 patiënten met tuberculose behandeld in het Academisch Medisch Centrum te Amsterdam Nederlands tijdschrift voor geneeskunde 1998;142 (4):180-184 [PubMed]
• Juffermans N. P., Verbon A., Danner S. A., Kuijper E. J., Speelman P. Mycobacterium xenopi in HIV-infected patients: an emerging pathogen AIDS (London, England) 1998;12 (13):1661-1666 [PubMed]
• Juffermans N. P., Verbon A., van Deventer S. J., Buurman W. A., van Deutekom H., Speelman P., van der Poll T. Serum concentrations of lipopolysaccharide activity-modulating proteins during tuberculosis Journal of infectious diseases 1998;178 (6):1839-1842 [PubMed]
• Juffermans N. P., Verbon A., Van Deventer S. J.H., Van Deutekom H., Speelman P., Van Der Poll T. Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis Pneumologie (Stuttgart, Germany) 1998;52 (11):625
• Juffermans N. P., Verbon A., van Deventer S. J., van Deutekom H., Speelman P., van der Poll T. Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis American journal of respiratory and critical care medicine 1998;157 (4 Part 1):1328-1331 [PubMed]